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All Outputs (94)

An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain (2016)
Journal Article
Jowett, S., Nicholls, E., Al-Janabi, H., Keeley, T., Coast, J., & Foster, N. (2016). An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain. Health and Quality of Life Outcomes, 36 -?. https://doi.org/10.1186/s12955-016-0430-x

BACKGROUND: The ICECAP measures potentially offer a broader assessment of quality of life and well-being, in comparison to measures routinely used in economic evaluation, such as the EQ-5D-3 L. This broader assessment may allow measurement of the ful... Read More about An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain.

Improving the care of people with long-term conditions in primary care: (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care:. Journal of Comorbidity, 2015(5), 135-149. https://doi.org/10.15256/joc.2015.5.60

Background Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused on... Read More about Improving the care of people with long-term conditions in primary care:.

A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention (2015)
Journal Article
Keeley, T., Al-Janabi, H., Nicholls, E., Foster, N., Jowett, S., & Coast, J. (2015). A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention. Quality of Life Research, 2319 - 2331. https://doi.org/10.1007/s11136-015-0980-0

PURPOSE: The ICECAP-A is a simple measure of capability well-being for use with the adult population. The descriptive system is made up of five key attributes: Stability, Attachment, Autonomy, Achievement and Enjoyment. Studies have begun to assess t... Read More about A longitudinal assessment of the responsiveness of the ICECAP-A in a randomised controlled trial of a knee pain intervention.

OP0105 Improving the Effectiveness of Exercise Therapy for Older Adults with Knee Osteoarthritis: A Pragmatic Randomised Controlled Trial (The Beep Trial) (2015)
Journal Article
Foster, N., Nicholls, E., Holden, M., Healey, E., Kigozi, J., Jowett, S., …Hay, E. (2015). OP0105 Improving the Effectiveness of Exercise Therapy for Older Adults with Knee Osteoarthritis: A Pragmatic Randomised Controlled Trial (The Beep Trial). Annals of the Rheumatic Diseases, 74(Suppl 2), 108.2-108. https://doi.org/10.1136/annrheumdis-2015-eular.1454

Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial (2015)
Journal Article
Healey, E. L., Jinks, C., Tan, V. A., Chew-Graham, C. A., Lawton, S. A., Nicholls, E., …Mallen, C. D. (2015). Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial. Journal of Comorbidity, 5(1), 135 -149. https://doi.org/10.15256/joc.2015.5.60

Background: Long-term conditions (LTCs) are important determinants of quality of life and healthcare expenditure worldwide. Whilst multimorbidity is increasingly the norm in primary care, clinical guidelines and the delivery of care remain focused o... Read More about Improving the care of people with long-term conditions in primary care: protocol for the ENHANCE pilot trial.

Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial. (2015)
Journal Article
Dziedzic, K., Nicholls, E., Hill, S., Hammond, A., Handy, J., Thomas, E., & Hay, E. (2015). Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial. Annals of the Rheumatic Diseases, 74(1), 108 - 118. https://doi.org/10.1136/annrheumdis-2013-203938

BACKGROUND: Osteoarthritis is the leading cause of disability in older adults. Evidence of effectiveness for self-management of hand osteoarthritis is lacking. METHODS: In this randomised, factorial trial, we evaluated the effectiveness of joint prot... Read More about Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial..

Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity? (2014)
Journal Article
Marshall, M., Nicholls, E., Kwok, W., Peat, G., Kloppenburg, M., Van Der Windt, D., …Dziedzic, K. (2014). Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?. Annals of the Rheumatic Diseases, 74(1), 136 - 141. https://doi.org/10.1136/annrheumdis-2013-203948

OBJECTIVES: To determine whether erosive osteoarthritis shares the same pattern of joint involvement and risk profile as increasing grades of non-erosive hand osteoarthritis. METHODS: Participants were from two population-based cohorts, aged =50 year... Read More about Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?.

Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials (2014)
Journal Article
Oppong, R., Jowett, S., Nicholls, E., Whitehurst, D., Hill, S., Hammond, A., …Dziedzic, K. (2015). Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials. Rheumatology, 54(5), 876 - 883. https://doi.org/10.1093/rheumatology/keu389

OBJECTIVES: Evidence regarding the cost-effectiveness of joint protection and hand exercises for the management of hand OA is not well established. The primary aim of this study is to assess the cost-effectiveness (cost-utility) of these management o... Read More about Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials.

Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative (2014)
Journal Article
Nicholls, E., Thomas, E., van der Windt, D., Croft, P., & Peat, G. (2014). Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 22(12), 2041 - 2050. https://doi.org/10.1016/j.joca.2014.09.026

OBJECTIVE: The authors aimed to characterize distinct trajectories of knee pain in adults who had, or were at high risk of, knee osteoarthritis using data from two population-based cohorts. METHOD: Latent class growth analysis was applied to measures... Read More about Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative.

A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563). (2014)
Journal Article
Healey, E. L., Holden, M. A., Nicholls, E., Whitehurst, D. G., Foster, N. E., Jowett, S., …Hay, E. M. (2014). A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563). BMC Musculoskeletal Disorders, 15, Article 254

BACKGROUND: Exercise is consistently recommended for older adults with knee pain related to osteoarthritis. However, the effects from exercise are typically small and short-term, likely linked to insufficient individualisation of the exercise program... Read More about A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three physiotherapy-led exercise interventions for knee osteoarthritis in older adults: the BEEP trial protocol (ISRCTN: 93634563)..

Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings. (2013)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., Van Der Windt, D., Myers, H., & Dziedzic, K. (2014). Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings. Arthritis Care & Research, 66(6), 828 - 836. https://doi.org/10.1002/acr.22225

OBJECTIVE: To investigate the reliability and construct validity of an atlas for grading hand osteoarthritis (OA) on photographs in a separate younger community-dwelling population than the development cohort. METHODS: Participants were community-dwe... Read More about Reliability of Assessing Hand Osteoarthritis on Digital Photographs and Associations With Radiographic and Clinical Findings..

Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies. (2013)
Journal Article
Kwok, W., Kloppenburg, M., Marshall, M., Nicholls, E., Rosendaal, F. R., Van Der Windt, D. A., & Peat, G. (2013). Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies. Rheumatology, 52(12), 2260 - 2267. https://doi.org/10.1093/rheumatology/ket267

OBJECTIVE: To investigate in the general population the clinical impact of erosive OA in interphalangeal joints (IPJs) compared with symptomatic radiographic hand OA and inflammatory arthritis. METHODS: Standardized assessments with hand radiographs... Read More about Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies..

Subsets of symptomatic hand osteoarthritis in community-dwelling older adults in the United Kingdom: prevalence, inter-relationships, risk factor profiles and clinical characteristics at baseline and 3-years. (2013)
Journal Article
Marshall, M., Peat, G., Nicholls, E., van der Windt, D., Myers, H., & Dziedzic, K. (2013). Subsets of symptomatic hand osteoarthritis in community-dwelling older adults in the United Kingdom: prevalence, inter-relationships, risk factor profiles and clinical characteristics at baseline and 3-years. Osteoarthritis and Cartilage, 21(11), 1674-1684. https://doi.org/10.1016/j.joca.2013.08.004

The long-term course of knee pain severity in middle and old age: distinct trajectories from latent class growth modelling in population cohort data (the CAS-K study and the osteoarthritis initiative (OAI)) (2013)
Journal Article
Nicholls, E., Thomas, E., Van der Windt, D., & Peat, G. (2013). The long-term course of knee pain severity in middle and old age: distinct trajectories from latent class growth modelling in population cohort data (the CAS-K study and the osteoarthritis initiative (OAI)). Osteoarthritis and Cartilage, 21, S39-S40. https://doi.org/10.1016/j.joca.2013.02.101

COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS (2013)
Journal Article
Oppong, R., Jowett, S., Nicholls, E., Whitehurst, D., Hill, S., Hammond, A., …Dziedzic, K. (2013). COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS. Rheumatology, 52(S1),

Background: European guidelines have proposed that joint protection and hand exercise should be used in the management of hand OA. However, the evidence regarding the cost-effectiveness of these interventions has not been well established. A 2x2 fact... Read More about COST-EFFECTIVENESS OF JOINT PROTECTION AND HAND EXERCISE FOR HAND OSTEOARTHRITIS.