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All Outputs (44)

Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method (2022)
Journal Article
Paskins, Z., Farmer, C. E., Manning, F., Andersson, D. A., Barlow, T., Bishop, F. L., Brown, C. A., Clark, A., Clark, E. M., Dulake, D., Gulati, M., Le Maitre, C. L., Jones, R. K., Loughlin, J., Mason, D. J., McCarron, M., Millar, N. L., Pandit, H., Peat, G., Richardson, S. M., …Watt, F. E. (2022). Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method. The Lancet Rheumatology, 4(9), E635-E645. https://doi.org/10.1016/S2665-9913%2822%2900136-9

Involving research users in setting priorities for research is essential to ensure research outcomes are patient-centred and to maximise research value and impact. The Musculoskeletal (MSK) Disorders Research Advisory Group Versus Arthritis led a res... Read More about Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method.

How do people with knee osteoarthritis perceive and manage flares? A qualitative study (2021)
Journal Article
Parry, E., Dikomitis, L., Peat, G., & Chew-Graham, C. (2022). How do people with knee osteoarthritis perceive and manage flares? A qualitative study. British Journal of General Practice Open (BJGP Open), 6(2), BJGPO.2021.0086 - BJGPO.2021.0086. https://doi.org/10.3399/BJGPO.2021.0086

Background Acute flares in people with osteoarthritis (OA) are poorly understood. There is uncertainty around the nature of flares, their impact, and how these are managed.

Aim To explore understandings and experiences of flares in people with kne... Read More about How do people with knee osteoarthritis perceive and manage flares? A qualitative study.

Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults. (2021)
Journal Article
Thomas, M., Rathod-Mistry, T., Parry, E., Pope, C., Neogi, T., & Peat, G. (2021). Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults. Osteoarthritis and Cartilage, 29(7), 956-964. https://doi.org/10.1016/j.joca.2021.04.007

OBJECTIVE: To identify proximate causes ('triggers') of flares in adults with, or at risk of, knee osteoarthritis (OA), estimate their course and consequences, and determine higher risk individuals. METHODS: In this 13-week web-based case-crossover s... Read More about Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults..

Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults (2020)
Journal Article
Clarke, G. R., Thomas, M. J., Rathod-Mistry, T., Marshall, M., Menz, H. B., Peat, G., & Roddy, E. (2020). Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults. Musculoskeletal Care, 18(3), 383-390. https://doi.org/10.1002/msc.1472

BACKGROUND: Hallux valgus (HV) is a common disabling condition affecting 36% of adults aged 65 years and over. Identifying whether the severity of the deformity alters weight-bearing patterns during walking may assist clinicians optimize offloading i... Read More about Hallux valgus severity, great toe pain, and plantar pressures during gait: A cross-sectional study of community-dwelling adults.

Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care (2019)
Journal Article
Appleyard, T., Ashworth, J., Bedson, J., Yu, D., & Peat, G. (2019). Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care. Osteoarthritis and Cartilage, 1437-1444. https://doi.org/10.1016/j.joca.2019.06.008

Summary Objective
To investigate trends in gabapentinoid prescribing in patients with osteoarthritis (OA).

Methods
Patients aged 40 years and over with a new OA diagnosis recorded between 1995 and 2015 were identified in the Clinical Practice Re... Read More about Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care.

Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study. (2019)
Journal Article
Blagojevic-Bucknall, M., Thomas, M. J., Wulff, J., Porcheret, M., Dziedzic, K. S., Peat, G. M., Foster, N. E., Jowett, S., & Van Der Windt, D. A. (2019). Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study. Musculoskeletal Care, 231-240. https://doi.org/10.1002/msc.1406

INTRODUCTION: There is little research on identifying modifiable risk factors that predict future interference of pain with daily activity in people with joint pain, and the estimation of the corresponding population attributable risk (PAR). The pres... Read More about Predictors of pain interference and potential gain from intervention in community dwelling adults with joint pain: A prospective cohort study..

Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study (2018)
Journal Article
Marshall, M., Peat, G., Nicholls, E., Myers, H. L., Mamas, M. A., & Van Der Windt, D. A. (in press). Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study. Scandinavian Journal of Rheumatology, 48(1), 52-63. https://doi.org/10.1080/03009742.2018.1459831

OBJECTIVE: To determine whether selected metabolic factors are associated with greater amounts of radiographic hand osteoarthritis (OA) incidence and progression. METHODS: The study identified 706 adults, aged 50-69 years, with hand pain and hand rad... Read More about Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study.

The natural history of flare-ups: a daily diary study of patients with, or at high risk of, knee osteoarthritis (2018)
Presentation / Conference Contribution
Parry, E., Ogollah, R., & Peat, G. (2018, April). The natural history of flare-ups: a daily diary study of patients with, or at high risk of, knee osteoarthritis. Presented at 2018 OARSI World Congress on Osteoarthritis, ACC Congress Center Liverpool, United Kingdom

Purpose: To determine, in a sample of community dwelling adults, the natural history of flare-ups in knee osteoarthritis (OA).

Methods: 330 adults aged 45 years and over with a recent primary care consultation for knee OA/arthralgia and no existin... Read More about The natural history of flare-ups: a daily diary study of patients with, or at high risk of, knee osteoarthritis.

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care (2017)
Journal Article
Mallen, C. D., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., Jowett, S., Kigozi, J., Belcher, J., Clarkson, K., Lingard, Z., Pope, C., Chew-Graham, C. A., Croft, P., Hay, E. M., & Peat, G. (2017). The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, e1002273 -?. https://doi.org/10.1371/journal.pmed.1002273

BACKGROUND: This study aimed to evaluate whether prompting general practitioners (GPs) to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis (OA) improves pain outcomes. METHODS AND FINDINGS: We conducted a... Read More about The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

Social gradient and regional variation and in general practice consultation prevalence for osteoarthritis in England 1998–2013: Descriptive epidemiological study using data from the Clinical Practice Research Datalink (2016)
Journal Article
Dutta, A., Wilkie, R., Yu, D., & Peat, G. (2016). Social gradient and regional variation and in general practice consultation prevalence for osteoarthritis in England 1998–2013: Descriptive epidemiological study using data from the Clinical Practice Research Datalink. Osteoarthritis and Cartilage, 24, S197-S198. https://doi.org/10.1016/j.joca.2016.01.389

Impairment-targeted exercises for older adults with knee pain: protocol for a proof-of-principle study. (2016)
Journal Article
Wood, L. R., Blagojevic-Bucknall, M., Stynes, S., D’Cruz, D., Mullis, R., Whittle, R., Peat, G., & Foster, N. E. (2016). Impairment-targeted exercises for older adults with knee pain: protocol for a proof-of-principle study. BMC Musculoskeletal Disorders, 17, Article 47. https://doi.org/10.1186/s12891-016-0899-9

BACKGROUND: Exercise therapy for knee pain and osteoarthritis remains a key element of conservative treatment, recommended in clinical guidelines. Yet systematic reviews point to only modest benefits from exercise interventions.One reason for this mi... Read More about Impairment-targeted exercises for older adults with knee pain: protocol for a proof-of-principle study..

The epidemiology of symptomatic midfoot osteoarthritis in community-dwelling older adults: cross-sectional findings from the Clinical Assessment Study of the Foot (2015)
Journal Article
Thomas, M. J., Peat, G., Rathod, T., Marshall, M., Moore, A., Menz, H. B., & Roddy, E. (2015). The epidemiology of symptomatic midfoot osteoarthritis in community-dwelling older adults: cross-sectional findings from the Clinical Assessment Study of the Foot. Arthritis Research and Therapy, 17, Article 178. https://doi.org/10.1186/s13075-015-0693-3

Introduction
The foot is largely overlooked in calls for better characterisation of clinical phenotypes in osteoarthritis (OA). Yet the midfoot complex in particular has the potential to provide important insights into OA pathogenesis given its cent... Read More about The epidemiology of symptomatic midfoot osteoarthritis in community-dwelling older adults: cross-sectional findings from the Clinical Assessment Study of the Foot.

Prodromal symptoms in knee osteoarthritis: a nested case-control study using data from the Osteoarthritis Initiative (2015)
Journal Article
Case, R., Thomas, E., Clarke, E., & Peat, G. (2015). Prodromal symptoms in knee osteoarthritis: a nested case-control study using data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 23(7), 1083-1089

Objective
In order to gain a better understanding of the timing of emergent symptoms of osteoarthritis, we sought to investigate the existence, duration and nature of a prodromal symptomatic phase preceding incident radiographic knee osteoarthritis... Read More about Prodromal symptoms in knee osteoarthritis: a nested case-control study using data from the Osteoarthritis Initiative.

Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative (2015)
Journal Article
Case, R., Thomas, E., Clarke, E., & Peat, G. (2015). Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 23(7), 1083-1089. https://doi.org/10.1016/j.joca.2014.12.026

Objective
In order to gain a better understanding of the timing of emergent symptoms of osteoarthritis, we sought to investigate the existence, duration and nature of a prodromal symptomatic phase preceding incident radiographic knee osteoarthritis... Read More about Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative.

The science of clinical practice: disease diagnosis or patient prognosis? Evidence about "what is likely to happen" should shape clinical practice (2015)
Journal Article
Croft, P., Altman, D. G., Deeks, J. J., Dunn, K. M., Hay, A. D., Hemingway, H., LeResche, L., Peat, G., Perel, P., Petersen, S. E., Riley, R. D., Roberts, I., Sharpe, M., Stevens, R. J., Van Der Windt, D. A., Von Korff, M., & Timmis, A. (2015). The science of clinical practice: disease diagnosis or patient prognosis? Evidence about "what is likely to happen" should shape clinical practice. BMC Medicine, 20. https://doi.org/10.1186/s12916-014-0265-4

BACKGROUND: Diagnosis is the traditional basis for decision-making in clinical practice. Evidence is often lacking about future benefits and harms of these decisions for patients diagnosed with and without disease. We propose that a model of clinical... Read More about The science of clinical practice: disease diagnosis or patient prognosis? Evidence about "what is likely to happen" should shape clinical practice.

Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative (2014)
Journal Article
Nicholls, E., Thomas, E., van der Windt, D., Croft, P., & Peat, G. (2014). Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 22(12), 2041 - 2050. https://doi.org/10.1016/j.joca.2014.09.026

OBJECTIVE: The authors aimed to characterize distinct trajectories of knee pain in adults who had, or were at high risk of, knee osteoarthritis using data from two population-based cohorts. METHOD: Latent class growth analysis was applied to measures... Read More about Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis Initiative.

Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols (2014)
Journal Article
Peat, G., Riley, R. D., Croft, P., Morley, K. I., Kyzas, P. A., Moons, K. G., Perel, P., Steyerberg, E. W., Schroter, S., Altman, D. G., Hemingway, H., & van der Windt, D. (2014). Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols. PLoS Medicine, e1001671 -?. https://doi.org/10.1371/journal.pmed.1001671

Prognosis research is concerned with predicting outcomes to make health care more effective. It has a crucial role to play in clinical and policy decision-making. The quality of much prognosis research is poor, evidenced by incomplete reporting, poor... Read More about Improving the transparency of prognosis research: the role of reporting, data sharing, registration, and protocols.