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Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method

Paskins, Zoe; Farmer, Clare E; Manning, Fay; Andersson, David A; Barlow, Tim; Bishop, Felicity L; Brown, Christopher A; Clark, Amanda; Clark, Emma M; Dulake, Debra; Gulati, Malvika; Le Maitre, Christine L; Jones, Richard K; Loughlin, John; Mason, Deborah J; McCarron, Maura; Millar, Neil L; Pandit, Hemant; Peat, George; Richardson, Stephen M; Salt, Emma J; Taylor, E Jane; Troeberg, Linda; Wilcox, Prof Ruth K; Wise, Elspeth; Wilkinson, Colin; Watt, Fiona E


Clare E Farmer

Fay Manning

David A Andersson

Tim Barlow

Felicity L Bishop

Christopher A Brown

Amanda Clark

Emma M Clark

Debra Dulake

Malvika Gulati

Christine L Le Maitre

Richard K Jones

John Loughlin

Deborah J Mason

Maura McCarron

Neil L Millar

Hemant Pandit

George Peat

Stephen M Richardson

Emma J Salt

E Jane Taylor

Linda Troeberg

Prof Ruth K Wilcox

Elspeth Wise

Colin Wilkinson

Fiona E Watt


Involving research users in setting priorities for research is essential to ensure research outcomes are patient-centred and to maximise research value and impact. The Musculoskeletal (MSK) Disorders Research Advisory Group Versus Arthritis led a research priority setting exercise across MSK disorders. The Child Health and Nutrition Research Initiative (CHRNI) method of setting research priorities with a range of stakeholders was utilised, involving four stages and two surveys, to: 1) gather research uncertainties; 2) consolidate these; 3) score uncertainties against importance and impact; and 4) analyse scoring, for prioritisation. 213 and 285 people responded to the first and second surveys respectively, representing clinicians, researchers and people with MSK disorders. Key priorities included developing and testing new treatments, better treatment targeting , early diagnosis, prevention and better understanding and management of pain, with an emphasis on understanding underpinning mechanisms. We present a call to action to researchers and funders to target these priorities.


Paskins, Z., Farmer, C. E., Manning, F., Andersson, D. A., Barlow, T., Bishop, F. L., …Watt, F. E. (2022). Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method. The Lancet Rheumatology, 4(9), E635-E645.

Journal Article Type Article
Acceptance Date May 6, 2022
Online Publication Date Jul 27, 2022
Publication Date 2022-09
Journal The Lancet Rheumatology
Print ISSN 2665-9913
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 4
Issue 9
Pages E635-E645
Publisher URL


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