All Outputs (7)

Erratum (2014)
Journal Article
Di Leva, G. (2014). Erratum. JNCI: Journal of the National Cancer Institute, 106(11), dju373-dju373. https://doi.org/10.1093/jnci/dju373

This is a correction to: JNCI: Journal of the National Cancer Institute, Volume 106, Issue 12, December 2014, dju324, https://doi.org/10.1093/jnci/dju324 Erratum: “Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer,” Stefano Vol... Read More about Erratum.

Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer (2014)
Journal Article
Volinia, S., Nuovo, G., Drusco, A., Costinean, S., Abujarour, R., Desponts, C., …Croce, C. M. (2014). Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer. JNCI: Journal of the National Cancer Institute, 106(12), https://doi.org/10.1093/jnci/dju324

Background The purpose of this study is to determine whether microRNA for pluripotent stem cells are also expressed in breast cancer and are associated with metastasis and outcome. Methods We studied global microRNA profiles during differentiati... Read More about Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer.

Correction for Romano et al., MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation (2014)
Journal Article
Romano, G., Acunzo, M., Garofalo, M., Di Leva, G., Cascione, L., Zanca, C., …Croce, C. M. (2014). Correction for Romano et al., MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation. Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10389-10389. https://doi.org/10.1073/pnas.1410423111

CELL BIOLOGY Correction for “MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation,” by Giulia Romano, Mario Acunzo, Michela Garofalo, Gianpiero Di Leva, Luciano Cascione, Ciro... Read More about Correction for Romano et al., MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation.

MicroRNA Profiles Discriminate among Colon Cancer Metastasis (2014)
Journal Article
Drusco, A., Nuovo, G. J., Zanesi, N., Di Leva, G., Pichiorri, F., Volinia, S., …Croce, C. M. (in press). MicroRNA Profiles Discriminate among Colon Cancer Metastasis. PloS one, 9(6), Article e96670. https://doi.org/10.1371/journal.pone.0096670

MicroRNAs are being exploited for diagnosis, prognosis and monitoring of cancer and other diseases. Their high tissue specificity and critical role in oncogenesis provide new biomarkers for the diagnosis and classification of cancer as well as predic... Read More about MicroRNA Profiles Discriminate among Colon Cancer Metastasis.

microRNAs as Anti-Cancer Therapy (2014)
Journal Article
Garofalo, M., Di Leva, G., & Croce, C. (2014). microRNAs as Anti-Cancer Therapy. Current Pharmaceutical Design, 20(33), 5328-5335. https://doi.org/10.2174/1381612820666140128211346

MicroRNAs (miRNAs) are endogenously expressed and evolutionarily conserved small non-coding RNAs, which regulate gene expression. Several studies have shown that they are involved in fundamental biological processes, such as proliferation and apoptos... Read More about microRNAs as Anti-Cancer Therapy.

MicroRNAs in Cancer (2014)
Journal Article
Di Leva, G., Garofalo, M., & Croce, C. M. (2014). MicroRNAs in Cancer. Annual Review of Pathology: Mechanisms of Disease, 9(1), 287-314. https://doi.org/10.1146/annurev-pathol-012513-104715

MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such as inflammation, cell-cycle regulation, stress response, differentiation... Read More about MicroRNAs in Cancer.

Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri (2014)
Journal Article
Folcik, V. A., Garofalo, M., Coleman, J., Donegan, J. J., Rabbani, E., Suster, S., …Nuovo, G. J. (2014). Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri. Modern Pathology, 27(6), 851-862. https://doi.org/10.1038/modpathol.2013.198

Idiopathic pulmonary fibrosis is a fatal disease without effective therapy or diagnostic test. To investigate a potential role for ?-herpesviruses in this disease, 21 paraffin-embedded lung biopsies from patients diagnosed with idiopathic pulmonary f... Read More about Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri.