All Outputs (4)

Characterization of miR-200 family members as blood biomarkers for human and laying hen ovarian cancer (2020)
Journal Article
Choi, P., Bahrampour, A., Ng, S., Liu, S. K., Qiu, W., Xie, F., …Ng, S. (in press). Characterization of miR-200 family members as blood biomarkers for human and laying hen ovarian cancer. Scientific reports, 10(1), https://doi.org/10.1038/s41598-020-77068-0

MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. We evaluated the levels of family members relative to the internal control miR-103a in ovarian cancer and control blood specimens collected from American and Hong Kong Chinese insti... Read More about Characterization of miR-200 family members as blood biomarkers for human and laying hen ovarian cancer.

Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer (2020)
Journal Article
kwong, J. (2020). Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer. BMC Cancer, https://doi.org/10.1186/s12885-020-07455-3

Abstract Background Previous studies have shown a major green tea polyphenol (-)-epigallocatechin-3-gallate ((-)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have... Read More about Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer.

Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis (2020)
Journal Article
Lau, T. S., Chan, L. K. Y., Man, G. C. W., Wong, C. H., Lee, J. H. S., Yim, S. F., …Kwong, J. (2020). Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis. Cancer Immunology Research, 8(8), 1099-1111. https://doi.org/10.1158/2326-6066.CIR-19-0616

Emerging evidence shows that the efficacy of chemotherapeutic drugs is reliant on their capability to induce immunogenic cell death (ICD), thus transforming dying tumor cells into antitumor vaccines. We wanted to uncover potential therapeutic strateg... Read More about Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis.

The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertile controls (2020)
Journal Article
Zhao, Y., Chen, X., Zhang, T., Chan, L. K. Y., Liu, Y., Chung, J. P., …Li, T. (2020). The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertile controls. Journal of Molecular Histology, 51(5), 593-603. https://doi.org/10.1007/s10735-020-09908-2