All Outputs (9)

Cell Therapies for Cartilage Repair and Osteoarthritis (2025)
Book Chapter
Jones, A., Hulme, C., Link, T., McCarthy, H., Maniar, Z., Perry, J., & Wright, K. (2025). Cell Therapies for Cartilage Repair and Osteoarthritis. In Cell Therapy - Stem Cells and Regenerative Medicine (323-341). Springer Nature [academic journals on nature.com]. https://doi.org/10.1007/978-981-96-1261-1_19

Osteoarthritis (OA) is a degenerative joint disease which results in dysfunction and pain. Articular cartilage is a specialised connective tissue which is structurally important to the healthy functioning of articulated joints, and damage to this tis... Read More about Cell Therapies for Cartilage Repair and Osteoarthritis.

028 Infrapatellar Fat Pad Synovitis and Macrophage Phenotypes in Early and End-Stage Osteoarthritis Cohorts (2025)
Presentation / Conference Contribution
Hopkins, T., Wright, K. T., Garcia, J., Hulme, C. H., Tins, B., Perry, J., Jermin, P., Gallacher, P., & Roberts, S. (2025, April). 028 Infrapatellar Fat Pad Synovitis and Macrophage Phenotypes in Early and End-Stage Osteoarthritis Cohorts. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

210 Intra-articular Arthrosamid® injection for knee osteoarthritis: A synovial fluid biomarker study (2025)
Presentation / Conference Contribution
Wright, K. T., Owen, S., Rix, L., Tins, B., Barnett, A., Glover, A., Roach, R., Jermin, P., & Snow, M. (2025, April). 210 Intra-articular Arthrosamid® injection for knee osteoarthritis: A synovial fluid biomarker study. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

758 A SINGLE INJECTION OF INTRA-ARTICULAR ARTHROSAMID FOR KNEE OSTEOARTHRITIS - A STUDY OF CLINICAL EFFICACY AND MECHANISM (2025)
Presentation / Conference Contribution
Snow, M., Tins, B., Owen, S., Roach, R., Rix, L., Glover, A., Barnett, A., Jermin, P., & Wright, K. T. (2025, April). 758 A SINGLE INJECTION OF INTRA-ARTICULAR ARTHROSAMID FOR KNEE OSTEOARTHRITIS - A STUDY OF CLINICAL EFFICACY AND MECHANISM. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

Clinical and Cellular Predictors of Outcomes in Autologous Conditioned Plasma Therapy for Knee Osteoarthritis: A Prospective Cohort Study (2025)
Journal Article
Selim, A., Lan, T., Hulme, C., Williams, M., Perry, J., Gallacher, P., Jermin, P., & Wright, K. (2025). Clinical and Cellular Predictors of Outcomes in Autologous Conditioned Plasma Therapy for Knee Osteoarthritis: A Prospective Cohort Study. Cartilage, https://doi.org/10.1177/19476035251323376

Introduction Autologous conditioned plasma (ACP) is a single-spin, leukocyte-poor platelet-rich plasma (PRP) that provides a plasma with a platelet concentration 2 to 3 times the blood platelet concentration. The objective of this study was to invest... Read More about Clinical and Cellular Predictors of Outcomes in Autologous Conditioned Plasma Therapy for Knee Osteoarthritis: A Prospective Cohort Study.

Characterisation of Bone Marrow Aspirate Concentrate with Thrombin Used for Repairing Osteochondral Lesions of the Talus (2025)
Journal Article
Lan, T., Wright, K. T., Makwana, N., Bing, A., Hulme, C. H., & McCarthy, H. S. (2025). Characterisation of Bone Marrow Aspirate Concentrate with Thrombin Used for Repairing Osteochondral Lesions of the Talus. The Journal of Cartilage & Joint Preservation, Article 100237. https://doi.org/10.1016/j.jcjp.2025.100237

A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome (2025)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Stokes-Fisher, J., Peffers, M., El Masri, W., Osman, A., Chowdhury, J. R., Kumar, N., Budithi, S., & Wright, K. (2025). A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome. Journal of Neurotrauma, 42(3-4), https://doi.org/10.1101/2022.07.12.499696

Spinal cord injury (SCI) is a major cause of disability, with complications postinjury often leading to lifelong health issues with the need for extensive treatment. Neurological outcome post-SCI can be variable and difficult to predict, particularly... Read More about A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome.

A Comprehensive Proteomic and Bioinformatic Analysis of Human Spinal Cord Injury Plasma Identifies Proteins Associated with the Complement Cascade and Liver Function as Potential Prognostic Indicators of Neurological Outcome (2025)
Journal Article
Mateus Bernardo Harrington, G., Cool, P., Hulme, C., Fisher-Stokes, J., Peffers, M., El Masri, W., Osman, A., Roy Chowdhury, J., Kumar, N., Budithi, S., & Wright, K. (2025). A Comprehensive Proteomic and Bioinformatic Analysis of Human Spinal Cord Injury Plasma Identifies Proteins Associated with the Complement Cascade and Liver Function as Potential Prognostic Indicators of Neurological Outcome. Journal of Neurotrauma, 42(3-4), 292-306. https://doi.org/10.1089/neu.2023.0064

Spinal cord injury (SCI) is a major cause of disability, with complications postinjury often leading to lifelong health issues with the need for extensive treatment. Neurological outcome post-SCI can be variable and difficult to predict, particularly... Read More about A Comprehensive Proteomic and Bioinformatic Analysis of Human Spinal Cord Injury Plasma Identifies Proteins Associated with the Complement Cascade and Liver Function as Potential Prognostic Indicators of Neurological Outcome.

Assessing SPECT/CT for the Identification of Cartilage Lesions in The Knee Joint: A Systematic Review (2025)
Journal Article
Rix, L., Tushingham, S., Wright, K., & Snow, M. (in press). Assessing SPECT/CT for the Identification of Cartilage Lesions in The Knee Joint: A Systematic Review. Osteoarthritis and Cartilage Open, 7(1), Article 100577. https://doi.org/10.1016/j.ocarto.2025.100577

Background
Single-photon emission computerised tomography with conventional computer tomography (SPECT/CT) is an emerging technology which may hold clinical value for the identification of cartilage lesions in the... Read More about Assessing SPECT/CT for the Identification of Cartilage Lesions in The Knee Joint: A Systematic Review.