The risk of keratinocyte carcinoma (KC) in psoriasis patients receiving biologic therapy compared with conventional systemic therapy: Results from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

Mason, Kayleigh J.

P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Poster presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

There are long-standing concerns that the use of biologic therapies to treat patients with psoriasis could confer an increased risk of developing cancer due to their immunomodulatory effects. We aimed to assess the risk of any incident cancer (exclud... Read More about P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

Previous literature suggests an association between the use of biologics and the development of keratinocyte carcinoma in psoriasis. Our aim was to evaluate the risks of developing basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC... Read More about O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study (2024)
Presentation / Conference
Mason, K. J., Jordan, K. P., Bailey, J., Jöud, A., Jowett, S., Protheroe, J., …Dunn, K. M. (2024, April). P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Musculoskeletal pain in childhood increases the risk of such pain in adulthood but there is an absence of management guidance for this group, not helped by a lack of evidence on the extent and nature of pain in children. The aim was... Read More about P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study.

P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data (2024)
Presentation / Conference
Akthar, M., Mason, K. J., & Scott, I. C. (2024, April). P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Inflammatory arthritis (IA) care involves a paradox. Rheumatologists focus on reducing disease activity through treat-to-target (T2T). But surveys/qualitative studies show patients’ main concern is pain. As these studies include a min... Read More about P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data.

POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY (2023)
Presentation / Conference
Bajpai, R., Burton, C., Mason, K., Bailey, J., Frisher, M., Jordan, K., …Welsh, V. (2023, May). POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY. Poster presented at EULAR 2023 European Congress of Rheumatology, Milan, Italy

Background Inflammatory rheumatic and musculoskeletal diseases (iRMDs), including rheumatoid arthritis (RA) and juveneille inflammatory arthritsi (JIA), are common and cause a high disease burden globally. Early diagnosis of iRMDs and subsequent time... Read More about POS0999-HPR THE IMPACT OF THE COVID-19 PANDEMIC ON REFERRALS TO MUSCULOSKELETAL SERVICES FROM PRIMARY CARE AND SUBSEQUENT INCIDENCE OF INFLAMMATORY RHEUMATIC MUSCULOSKELETAL DISEASE: AN OBSERVATIONAL STUDY.

P103 The impact of the COVID-19 pandemic on primary care referrals and new diagnoses of inflammatory arthritis (2023)
Presentation / Conference
Bajpai, R., Burton, C., Mason, K. J., Bailey, J., Jordan, K. P., Mallen, C. D., & Welsh, V. (2023, April). P103 The impact of the COVID-19 pandemic on primary care referrals and new diagnoses of inflammatory arthritis. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Real-world effectiveness and persistence of methotrexate versus adalimumab: A comparative study from the British association of dermatologists biologics and immunomodulators register (BADBIR) (2022)
Presentation / Conference
Alabas, O., Mason, K., Yiu, Z., Warren, R., Lunt, M., Smith, C., & Griffiths, C. (2022, August). Real-world effectiveness and persistence of methotrexate versus adalimumab: A comparative study from the British association of dermatologists biologics and immunomodulators register (BADBIR). Presented at 38th International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE), Copenhagen, Denmark

Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM) (2022)
Presentation / Conference
Mason, K., Bailey, J., Heron, N., Marshall, M., Achana, F., Chen, Y., …Jordan, K. (2022, July). Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM). Paper presented at SAPC ASM 2022 - UCLan 50th Annual Scientific Meeting, University of Central Lancashire, UK

Background: Patients with painful musculoskeletal conditions have an increased risk of developing cancer, but less is known about whether this impacts on the longer-term cancer prognosis. This study aims to determine whether patients with painful mus... Read More about Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM).

Psoriasis and COVID-19: findings from PsoProtectMe. (2021)
Presentation / Conference
McGrath, C., Yates, M., Yiu, Z., Langan, S., Tsakok, T., Dand, N., …Mahil, S. (2021, December). Psoriasis and COVID-19: findings from PsoProtectMe

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mallen, Mason, Frisher, Mamas, Jordan, Marshall, …White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

The impact of the COVID-19 pandemic on people with psoriasis: findings from a global patient-reported registry (2021)
Presentation / Conference
Mahil, S., Yates, M., Yiu, Z., Langan, S., Tsakok, T., Dand, N., …Smith, C. (2021, July). The impact of the COVID-19 pandemic on people with psoriasis: findings from a global patient-reported registry. Presented at British Association of Dermatologists 101st Annual Meeting, Virtual Meeting

189 Prevalence of comorbidities and the incidence of cardiovascular disease in those with non-cardiac chest pain (2021)
Presentation / Conference
Ramesh, S., Mason, K., Bailey, J., Mamas, M., & Jordan, K. (2021, June). 189 Prevalence of comorbidities and the incidence of cardiovascular disease in those with non-cardiac chest pain. Paper presented at British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021

Factors associated with hospitalization due to COVID‐19 in patients with psoriasis: insights from a global registry (2020)
Presentation / Conference
Mahil, S., Dand, N., Mason, K., Yiu, Z., Tsakok, T., Meynell, F., …Smith, C. (2020, July). Factors associated with hospitalization due to COVID‐19 in patients with psoriasis: insights from a global registry. Paper presented at British Association of Dermatologists 100th Annual Meeting, Virtual

Psoriasis is a common immune‐mediated inflammatory skin disease with frequent multimorbidity, and immunosuppressants are the mainstay of treatment in moderate‐to‐severe disease. An understanding of the impact of COVID‐19 on individuals with psoriasis... Read More about Factors associated with hospitalization due to COVID‐19 in patients with psoriasis: insights from a global registry.

Real-world effectiveness of methotrexate, ciclosporin, acitretin and fumaric acid esters for psoriasis: Does treatment history matter? (2019)
Presentation / Conference
Mason, K. J. (2019, August). Real-world effectiveness of methotrexate, ciclosporin, acitretin and fumaric acid esters for psoriasis: Does treatment history matter?. Poster presented at 35th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Pennsylvania Convention Center, Philadelphia, PA, USA

Background: Real-world effectiveness of the systemic therapies methotrexate (MTX), ciclosporin (CsA), acitretin (ACI) and fumaric acid esters (FAE) prescribed to patients with moderate–severe psoriasis is poorly characterized. Objectives: To deter... Read More about Real-world effectiveness of methotrexate, ciclosporin, acitretin and fumaric acid esters for psoriasis: Does treatment history matter?.

The risk of melanoma in patients with immune-mediated inflammatory diseases exposed to biological therapies: systematic review and meta-analysis (2019)
Presentation / Conference
Esse, S., Mason, K. J., Green, A. C., & Warren, R. B. (2019, July). The risk of melanoma in patients with immune-mediated inflammatory diseases exposed to biological therapies: systematic review and meta-analysis. Poster presented at BRITISH ASSOCIATION OF DERMATOLOGISTS 99TH ANNUAL MEETING, LIVERPOOL, U.K

Biological therapies are used in the treatment of immunemediated inflammatory diseases (IMIDs), including moderateto-severe psoriasis, rheumatoid arthritis (RA), psoriatic arthritis (PsA) and inflammatory bowel disease (IBD). Melanoma is a highly i... Read More about The risk of melanoma in patients with immune-mediated inflammatory diseases exposed to biological therapies: systematic review and meta-analysis.

Real-world persistence and effectiveness of conventional systemic therapies in the treatment of psoriasis: A systematic review (2018)
Presentation / Conference
Williams, S., Mason, K. J., Yiu, Z., McElhone, K., Warren, R. B., & Griffiths, C. E. (2018, August). Real-world persistence and effectiveness of conventional systemic therapies in the treatment of psoriasis: A systematic review. Paper presented at 34th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Prague Congress Centre, Prague, Czech Republic

Background: The effectiveness and persistence of biologic therapies is better understood than more commonly prescribed conventional systemic therapies in clinical practice. Objectives: To evaluate large-scale observational studies investigating th... Read More about Real-world persistence and effectiveness of conventional systemic therapies in the treatment of psoriasis: A systematic review.

The risk of keratinocyte carcinoma (KC) in psoriasis patients receiving biologic therapy compared with conventional systemic therapy: Results from the British Association of Dermatologists Biologic Interventions Register (BADBIR) (2018)
Presentation / Conference
Mason, K. J. (2018, August). The risk of keratinocyte carcinoma (KC) in psoriasis patients receiving biologic therapy compared with conventional systemic therapy: Results from the British Association of Dermatologists Biologic Interventions Register (BADBIR). Poster presented at 34th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Prague Congress Centre, Prague, Czech Republic

Background: Whether psoriasis patients exposed to biologic therapies have an elevated risk of KC (basal cell carcinoma [BCC] or cutaneous squamous cell carcinoma [cSCC]) remains uncertain. Objectives: To determine whether such patients were at hig... Read More about The risk of keratinocyte carcinoma (KC) in psoriasis patients receiving biologic therapy compared with conventional systemic therapy: Results from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

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