All Outputs (19)

Correlates of early child development among children with stunting: A cross‐sectional study in Uganda (2024)
Journal Article
Mbabazi, J., Pesu, H., Mutumba, R., Bromley, K., Ritz, C., Filteau, S., …Olsen, M. F. (in press). Correlates of early child development among children with stunting: A cross‐sectional study in Uganda. Maternal and Child Nutrition, Article e13619. https://doi.org/10.1111/mcn.13619

Many children in low‐ and middle‐income countries are not attaining their developmental potential. Stunting is associated with poor child development, but it is not known which correlates of stunting are impairing child development. We explored poten... Read More about Correlates of early child development among children with stunting: A cross‐sectional study in Uganda.

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis (2023)
Journal Article
Kigozi, J., Oppong, R., Paskins, Z., Bromley, K., Lewis, M., Hughes, G., …Roddy, E. (2023). The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis. Rheumatology, https://doi.org/10.1093/rheumatology/kead659

Objectives. Evidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT) comprising... Read More about The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Neurodevelopment among children born after obstructed labour in Eastern Uganda (2023)
Presentation / Conference
Chebet, M., Musaba, M., Mukunya, D., Auma, P., Makoko, B., Napyo, A., …Kiguli, S. (2023, November). Neurodevelopment among children born after obstructed labour in Eastern Uganda. Presented at 13th European Congress on Tropical Medicine and International Health (ECTMIH 2023), Shaping the future of equitable and sustainable planetary health, Utrecht, The Netherlands

Supplement: Abstracts of the , 20–, November 2023

Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article
Hawarden, A., Holden, M. A., Paskins, Z., Roddy, E., Mallen, C. D., Liddle, J., …Jinks, C. (2023). Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study. Musculoskeletal Care, https://doi.org/10.1002/msc.1830

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic, or local anaesthetic alone, to advice and education among people with... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study.

Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs (2023)
Report
E Foster, N., M Dunn, K., Protheroe, J., C Hill, J., Lewis, M., Saunders, B., …Chudyk, A. (2023). Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs. NIHR

Background Usual primary care for patients with musculoskeletal pain varies widely and treatment outcomes are suboptimal. Stratified care involves targeting treatments according to patient subgroups, in the hope of maximising treatment benefit and re... Read More about Stratified primary care for adults with musculoskeletal pain: the STarT MSK research programme including RCTs.

High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study. (2023)
Journal Article
Bromley. (2023). High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph20043470

Over 250 million infants in low and middle-income countries do not fulfill their neurodevelopment potential. In this study, we assessed the incidence and risk factors for neurodevelopmental delay (NDD) among children born following obstructed labor i... Read More about High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study..

The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data (2023)
Journal Article
McCray, G., McCoy, D., Kariger, P., Janus, M., Black, M. M., Chang, S. M., …Gladstone, M. (2023). The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data. BMJ Global Health, 8(1), https://doi.org/10.1136/bmjgh-2022-009827

INTRODUCTION: With the ratification of the Sustainable Development Goals, there is an increased emphasis on early childhood development (ECD) and well-being. The WHO led Global Scales for Early Development (GSED) project aims to provide population an... Read More about The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data.

Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial (2022)
Journal Article
Hill, J. C., Garvin, S., Bromley, K., Saunders, B., Kigozi, J., Cooper, V., …Foster, N. E. (2022). Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial. The Lancet Rheumatology, 4(9), e591 - e602. https://doi.org/10.1016/S2665-9913%2822%2900159-X

Background Risk-based stratified care shows clinical effectiveness and cost-effectiveness versus usual primary care for non-specific low back pain but is untested for other common musculoskeletal disorders. We aimed to test the clinical effectiveness... Read More about Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial.

Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial (2022)
Journal Article
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Hennings, S., …Mallen, C. D. (2022). Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial. BMJ, 377, Article ARTN e068446. https://doi.org/10.1136/bmj-2021-068446

Objectives: to compare the clinical effectiveness of best current treatment (BCT) plus single ultrasound-guided intra-articular hip injection (USGI) of 40mg triamcinolone acetonide and 4ml 1% lidocaine hydrochloride [BCT+US-Triamcinolone-Lidocaine] w... Read More about Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.

Rehabilitation following rotator cuff repair: Multi-centre pilot and feasibility randomised controlled trial (RaCeR) (2021)
Journal Article
Littlewood, C., Bateman, M., Butler-Walley, S., Bathers, S., Cookson, T., Bromley, K., …Foster, N. (2021). Rehabilitation following rotator cuff repair: Multi-centre pilot and feasibility randomised controlled trial (RaCeR). Physiotherapy, 113(S1), e13-e14. https://doi.org/10.1016/j.physio.2021.10.238

Purpose: Shoulder pain is a highly prevalent complaint and disorders of the rotator cuff, including tears, are thought to be the most common cause. The number of operations to repair the torn rotator cuff has risen significantly in recent years. Whil... Read More about Rehabilitation following rotator cuff repair: Multi-centre pilot and feasibility randomised controlled trial (RaCeR).

Determining sample size for progression criteria for pragmatic pilot RCTs: the hypothesis test strikes back! (2021)
Journal Article
Lewis, M., Bromley, K., Sutton, C., McCray, G., Myers, H., & Lancaster, G. (2021). Determining sample size for progression criteria for pragmatic pilot RCTs: the hypothesis test strikes back!. Pilot and Feasibility Studies, 7, Article 40. https://doi.org/10.1186/s40814-021-00770-x

BACKGROUND: The current CONSORT guidelines for reporting pilot trials do not recommend hypothesis testing of clinical outcomes on the basis that a pilot trial is under-powered to detect such differences and this is the aim of the main trial. It state... Read More about Determining sample size for progression criteria for pragmatic pilot RCTs: the hypothesis test strikes back!.

Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR) (2020)
Journal Article
Littlewood, C., Bateman, M., Butler-Walley, S., Bathers, S., Bromley, K., Lewis, M., …Foster, N. E. (2020). Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR). Clinical Rehabilitation, 35(6), 829-839. https://doi.org/10.1177/0269215520978859

OBJECTIVE: To evaluate the feasibility of a multi-centre randomised controlled trial to compare the clinical and cost-effectiveness of early patient-directed rehabilitation versus standard rehabilitation following surgical repair of the rotator cuff... Read More about Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR).

O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT) (2020)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2020, April). O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT). Presented at British Society for Rheumatology Annual Conference 2020, Glasgow, Scotland, UK

Background Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared the clinical and cost-effectiveness of an ultrasound-guided intra-articular hip injection (USGI) of 4... Read More about O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT).

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., …Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs (2019)
Conference Proceeding
Lewis, M., Bromley, K., McCray, G., Sutton, C., & Lancaster, G. (2019). Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs.

Introduction: The current CONSORT guidelines for reporting of pilot trials do not recommend hypothesis testing of clinical outcomes on the basis of a pilot trial being under-powered to detect such differences and this being the aim of the main tria... Read More about Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs.

Effect-based traffic light progression criteria for pilot studies (2019)
Presentation / Conference
McCray, G., Lewis, M., Bromley, K., & Lancaster, G. (2019, October). Effect-based traffic light progression criteria for pilot studies. Paper presented at 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK

Meeting abstract, from the 5th International Clinical Trials Methodology Conference (ICTMC 2019).

The global scale for early development (GSED) (2019)
Journal Article
Black, M., Bromley, K., Cavallera, V., Cuartas, J., Dua, T., Eekhout, I., …Weber, A. (2019). The global scale for early development (GSED). Early childhood matters,

Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study) (2019)
Journal Article
Littlewood, C., Bateman, M., Cooke, K., Hennnings, S., Cookson, T., Bromley, K., …Foster, N. E. (2019). Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study). Trials, 20, Article 328. https://doi.org/10.1186/s13063-019-3407-3

Background Shoulder pain is a highly prevalent complaint and disorders of the rotator cuff, including tears, are thought to be the most common cause. The number of operations repair the torn rotator cuff has risen significantly in recent years. Whil... Read More about Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study).

A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol (2018)
Journal Article
Paskins, Z., Hughes, G., Myers, H., Hughes, E., Hennings, S., Cherrington, A., …Roddy, E. (2018). A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol. BMC Musculoskeletal Disorders, 19, Article 218. https://doi.org/10.1186/s12891-018-2153-0

BACKGROUND: Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity over 6 months, in people with... Read More about A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.