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Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population. (2021)
Journal Article
Sattar, Y., Mukuntharaj, P., Zghouzi, M., Suleiman, A. M., Attique, H., Ullah, W., …Alraies, M. C. (2021). Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population. High Blood Pressure and Cardiovascular Prevention, 405 - 416. https://doi.org/10.1007/s40292-021-00462-w

INTRODUCTION: The safety of renin-angiotensin-aldosterone system inhibitors (RAASi) among COVID-19 patients has been controversial since the onset of the pandemic. METHODS: Digital databases were queried to study the safety of RAASi in COVID-19. The... Read More about Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population..

Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction. (2021)
Journal Article
Mamas. (2021). Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction. https://doi.org/10.1016/j.amjcard.2021.03.057

Chronic kidney disease (CKD) in patients with ST-elevation myocardial infarction (STEMI) is associated with worse outcomes. We assessed the impact of CKD on guideline directed coronary revascularization and outcomes among STEMI patients. The Nationwi... Read More about Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction..

In‐hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease (2021)
Journal Article
Zghouzi, M., Moussa Pacha, H., Ullah, W., Sattar, Y., Ahmad, B., Osman, H., …Alraies, M. C. (in press). In‐hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease. Catheterization and Cardiovascular Interventions, 98(4), https://doi.org/10.1002/ccd.29827

Background The outcome of endovascular intervention (EVI) compared vs. surgical revascularization in patients with peripheral artery disease (PAD) due to chronic total occlusion (CTO) is unknown. Methods Using the National Inpatient Sample datab... Read More about In‐hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease.

Coronary revascularisation outcomes in patients with cancer. (2021)
Journal Article
Mamas. (2021). Coronary revascularisation outcomes in patients with cancer. Heart, 507 - 516. https://doi.org/10.1136/heartjnl-2020-318531

Cancer and coronary artery disease (CAD) overlap in traditional risk factors as well as molecular mechanisms underpinning the development of these two disease states. Patients with cancer are at increased risk of developing CAD, representing a high-r... Read More about Coronary revascularisation outcomes in patients with cancer..

Effect of Location on Treatment and Outcomes of Cardiac Arrest Complicating Acute Myocardial Infarction in England & Wales. (2021)
Journal Article
Dafaalla, M., Rashid, M., Weston, C., Kinnaird, T., Gurm, H., Appleby, C., …Mamas, M. (2021). Effect of Location on Treatment and Outcomes of Cardiac Arrest Complicating Acute Myocardial Infarction in England & Wales. American Journal of Cardiology, 152, 1 - 10. https://doi.org/10.1016/j.amjcard.2021.04.032

We investigated the incidence, management, and outcomes of acute myocardial infarction (AMI) patients according to cardiac arrest location. Patients admitted with a diagnosis of AMI between January 1, 2010 to March 31, 2017 from the Myocardial Ischae... Read More about Effect of Location on Treatment and Outcomes of Cardiac Arrest Complicating Acute Myocardial Infarction in England & Wales..

Higher anticholinergic burden from medications is associated with significant increase in markers of inflammation in the EPIC-Norfolk prospective population-based cohort study (2021)
Journal Article
Mamas. (2021). Higher anticholinergic burden from medications is associated with significant increase in markers of inflammation in the EPIC-Norfolk prospective population-based cohort study. https://doi.org/10.22541/au.162273979.95865645/v1

Background: Higher anticholinergic burden from medications is associated with increased risk of cardiovascular disease and cognitive function decline. A mechanistic pathway has never been established. We aimed to determine whether chronic inflammati... Read More about Higher anticholinergic burden from medications is associated with significant increase in markers of inflammation in the EPIC-Norfolk prospective population-based cohort study.

Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study. (2021)
Journal Article
Mamas, & Rashid. (2021). Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study. Thrombosis Research, 17 - 23. https://doi.org/10.1016/j.thromres.2021.03.006

BACKGROUND: Evidence supports an excess of deaths during the COVID-19 pandemic. We report the incidence and mortality of thrombo-embolic events (TE) during the COVID-19 pandemic. METHODS: Multi-sourced nationwide cohort study of adults (age =18 years... Read More about Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study..

Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England. (2021)
Journal Article
Mamas, & Nolan. (2021). Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England. Circulation: Cardiovascular Interventions, 532-543. https://doi.org/10.1161/CIRCINTERVENTIONS.120.010413

Background: Aortic stenosis requires timely treatment with either surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). This study aimed to investigate the indirect impact of coronavirus disease 2019 (COVID-19) o... Read More about Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England..

Sex-Based Differences in Prevalence and Outcomes of Common Acute Conditions Associated With Type 2 Myocardial Infarction. (2021)
Journal Article
Mohamed, M. O., Contractor, T., Abramov, D., Parwani, P., Michos, E. D., Fischman, D., …Mamas, M. (2021). Sex-Based Differences in Prevalence and Outcomes of Common Acute Conditions Associated With Type 2 Myocardial Infarction. https://doi.org/10.1016/j.amjcard.2021.02.011

Little is known about the association between acute prevalent conditions in patients with type 2 Myocardial Infarction (T2MI) and clinical outcomes, particularly between genders. Using the Nationwide Inpatient Sample (2017), we examined outcomes of T... Read More about Sex-Based Differences in Prevalence and Outcomes of Common Acute Conditions Associated With Type 2 Myocardial Infarction..

Association of admitting physician specialty and care quality and outcomes in non-ST-segment elevation myocardial infarction (NSTEMI): insights from a national registry. (2021)
Journal Article
Moledina, S. M., Shoaib, A., Graham, M. M., Biondi-Zoccai, G., Van Spall, H. G. C., Kontopantelis, E., …Mamas, M. A. (2022). Association of admitting physician specialty and care quality and outcomes in non-ST-segment elevation myocardial infarction (NSTEMI): insights from a national registry. European Heart Journal - Quality of Care and Clinical Outcomes, 8(5), 557–567. https://doi.org/10.1093/ehjqcco/qcab038

BACKGROUND: Little is known about the association between admitting physician specialty and care quality and outcomes for non-ST-segment elevation myocardial infarction (NSTEMI). METHODS & RESULTS: We identified 288,420 patients hospitalised with NST... Read More about Association of admitting physician specialty and care quality and outcomes in non-ST-segment elevation myocardial infarction (NSTEMI): insights from a national registry..

Prognostic impact of comorbidity measures on outcomes following acute coronary syndrome: a systematic review. (2021)
Journal Article
Mamas. (2021). Prognostic impact of comorbidity measures on outcomes following acute coronary syndrome: a systematic review. International Journal of Clinical Practice, e14345 - ?. https://doi.org/10.1111/ijcp.14345

AIM: To identify existing comorbidity measures and summarise their association with acute coronary syndrome (ACS) outcomes. METHODS: We searched published studies from MEDLINE (OVIDSP) and EMBASE from inception to March 2021, studies of the pre-speci... Read More about Prognostic impact of comorbidity measures on outcomes following acute coronary syndrome: a systematic review..

Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique (2021)
Journal Article
Mamas, Rashid, & Rashid. (2021). Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique. EuroIntervention, https://doi.org/10.4244/EIJ-D-20-01393

Background: Optimal deployment of coronary stents in a bifurcation lesion remains a matter of debate. Aims: We sought to capture the daily practice of bifurcation stenting by means of a worldwide registry and to investigate how the post-implantati... Read More about Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique.

Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients (2021)
Journal Article
Rashid, M., Shoaib, A., Mohamed, M., Curzen, N., Ludman, P., Zaman, A., …Mamas, M. A. (2021). Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients. Catheterization and Cardiovascular Interventions, 99(1), 74-84. https://doi.org/10.1002/ccd.29691

OBJECTIVE: To compare the clinical characteristics and outcomes in patients with stable angina who have undergone chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in native arteries with or without prior coronary artery bypass g... Read More about Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients.

Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study (2021)
Journal Article
Mamas. (2021). Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study. Cancers, 2193 - 2193. https://doi.org/10.3390/cancers13092193

Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis (IVT) and endovascular... Read More about Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study.

HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS (2021)
Journal Article
Zghouzi, M., Ullah, W., Sandhyavenu, H., Pacha, H. M., Al-Khadra, Y., Ahmad, B., …Alraies, M. C. (2021). HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS. Journal of the American College of Cardiology, 77(18), 1042. https://doi.org/10.1016/s0735-1097%2821%2902401-3

Background Hybrid coronary artery revascularization (HCR) refers to complete or near complete revascularization using the combination of single vessel CABG and PCI of other significant coronary lesions. The short-term outcomes of HCR compared to CAB... Read More about HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS.

META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION (2021)
Journal Article
Sattar, Y., Mukuntharaj, P., Attique, H., Ullah, W., Sana, M. K., Zaher, N., …Alraies, M. C. (2021). META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION. Journal of the American College of Cardiology, 77(18 S1), 3158. https://doi.org/10.1016/s0735-1097%2821%2904513-7

Background The safety and efficacy of Renin Angiotensin Aldosterone System Inhibitors(RAASi) in COVID 19 patients has been controversial. Methods Digital databases were queried for relevant articles. A random-effect model was used to compute an... Read More about META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION.

THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY (2021)
Journal Article
Averbuch, T., Mohamed, M., Islam, S., Martin, G., Thabane, L., Mamas, M., & Van Spall, H. G. (2021). THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY. Journal of the American College of Cardiology, 77(18), 794. https://doi.org/10.1016/s0735-1097%2821%2902153-7

Background Heart failure (HF) hospitalization is associated with high mortality. We aimed to assess the role of race, sex, and socioeconomic status (SES) in the risk of in-hospital mortality among patients hospitalized for HF. Methods We used th... Read More about THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY.