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Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer (2024)
Journal Article
Ajabnoor, A. M., Zghebi, S. S., Parisi, R., Ashcroft, D. M., Faivre-Finn, C., Mamas, M. A., & Kontopantelis, E. (2024). Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer. European Heart Journal Open, 4(4), Article oeae053. https://doi.org/10.1093/ehjopen/oeae053

Aims: To compare the predictive performance of CHA2DS2-VASc and HAS-BLED scores in atrial fibrillation (AF) patients with and without cancer. Methods and results: Using data from the Clinical Practice Research Datalink in England, we performed a retr... Read More about Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer.

Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences (2024)
Journal Article
Zaheer, A., Qiu, F., Manoragavan, R., Madan, M., Sud, M., Mamas, M. A., & Wijeysundera, H. C. (2024). Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences. Journal of the American Heart Association, 13(12), https://doi.org/10.1161/jaha.123.032450

Background Transcatheter aortic valve replacement (TAVR) has become the standard of care for severe aortic stenosis treatment. Exponential growth in demand has led to prolonged wait times and adverse patient outcomes. Social marginalization may contr... Read More about Impact of Neighborhood Social Deprivation on Delays to Access for Transcatheter Aortic Valve Replacement: Wait‐Times and Clinical Consequences.

Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy (2024)
Journal Article
Diaz-Arocutipa, C., Moreno, G., Giráldez, M., Hernandez, A. V., Mamas, M. A., & Vicent, L. (2024). Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy. CJC Open, https://doi.org/10.1016/j.cjco.2024.05.013

Background There is limited data examining potential sex-based disparities in the utilization and complications of septal reduction therapy (SRT) in patients with obstructive hypertrophic cardiomyopathy (HCM). Our aim was t... Read More about Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy.

The prognostic value of metabolic dysfunction-associated steatotic liver disease in acute myocardial infarction: A propensity score-matched analysis. (2024)
Journal Article
Kong, G., Cao, G., Koh, J., Chan, S. P., Zhang, A., Wong, E., …Loh, P. (in press). The prognostic value of metabolic dysfunction-associated steatotic liver disease in acute myocardial infarction: A propensity score-matched analysis. Diabetes, Obesity and Metabolism, https://doi.org/10.1111/dom.15660

Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) are at increased risk of incident cardiovascular disease. However, the clinical characteristics and prognostic importance of MASLD in patients presenting with acute myocar... Read More about The prognostic value of metabolic dysfunction-associated steatotic liver disease in acute myocardial infarction: A propensity score-matched analysis..

Sex differences in transcatheter aortic valve replacement outcomes among patients with bicuspid aortic stenosis. (2024)
Journal Article
Rivera, F. B., Cha, S. W., Redula, S. C., Liston, M. B. O., Ong, E. P., Bantayan, N. R. B., …Mamas, M. A. (2024). Sex differences in transcatheter aortic valve replacement outcomes among patients with bicuspid aortic stenosis. Heart and Lung, 67, 144-151. https://doi.org/10.1016/j.hrtlng.2024.05.003

Despite comprising almost half of all patients undergoing valvular repair, data on transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic stenosis (BAS) are limited. We aimed to evaluate whether there are any sex differences i... Read More about Sex differences in transcatheter aortic valve replacement outcomes among patients with bicuspid aortic stenosis..

Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis (2024)
Journal Article
Thuemmler, R. J., Pana, T. A., Carter, B., Mahmood, R., Bettencourt-Silva, J. H., Metcalf, A. K., …Myint, P. K. (in press). Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis. Nutrients, 16(10), Article 1486. https://doi.org/10.3390/nu16101486

Hypoalbuminemia associates with poor acute ischemic stroke (AIS) outcomes. We hypothesised a non-linear relationship and aimed to systematically assess this association using prospective stroke data from the Norfolk and Norwich Stroke and TIA Registe... Read More about Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis.

Calibration plots for multistate risk predictions models (2024)
Journal Article
Pate, A., Sperrin, M., Riley, R. D., Peek, N., Van Staa, T., Sergeant, J. C., …Martin, G. P. (in press). Calibration plots for multistate risk predictions models. Statistics in Medicine, https://doi.org/10.1002/sim.10094

Introduction There is currently no guidance on how to assess the calibration of multistate models used for risk prediction. We introduce several techniques that can be used to produce calibration plots for the transition probabilities of a multistat... Read More about Calibration plots for multistate risk predictions models.

Rural-Urban Stroke Mortality Gaps in the United States. (2024)
Journal Article
Chang, D., Ibrahim, R., Pham, H. N., Sainbayar, E., Shahid, M., Makkieh, M., …Lee, K. (in press). Rural-Urban Stroke Mortality Gaps in the United States. Journal of Stroke and Cerebrovascular Diseases, 33(8), Article 107762. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107762

Disparities in stroke outcomes, influenced by the use of systemic thrombolysis, endovascular therapies, and rehabilitation services, have been identified. Our study assesses these disparities in mortality after stroke between rural and urban areas ac... Read More about Rural-Urban Stroke Mortality Gaps in the United States..

Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (2024)
Journal Article
Mohamed, M. O., Kontopantelis, E., Alasnag, M., Abid, L., Banerjee, A., Sharp, A. S. P., …Mamas, M. A. (2024). Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention. Journal of the American Heart Association, 13(9), Article e034414. https://doi.org/10.1161/JAHA.124.034414

Over the past decade, major society guidelines have recommended the use of newer P2Y inhibitors over clopidogrel for those undergoing percutaneous coronary intervention for acute coronary syndrome. It is unclear what impact these recommendations had... Read More about Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention.

E-40 | Transcatheter Aortic Valve Replacement versus Surgical Aortic Valve Replacement in Patients with Bicuspid Aortic Stenosis: A Propensity Score Matching Analysis (2024)
Presentation / Conference
Rivera, F. B., Cha, S. W., Shiza, S., Redula, S., Liston, M., Carado, G., …Mamas, M. A. (2024, May). E-40 | Transcatheter Aortic Valve Replacement versus Surgical Aortic Valve Replacement in Patients with Bicuspid Aortic Stenosis: A Propensity Score Matching Analysis. Poster presented at Society for Cardiovascular Angiography & Interventions 47th Annual Scientific Sessions, Long Beach, California

Indirect impact of the war in Ukraine on primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in Poland (2024)
Journal Article
Mamas, M. A., Martin, G. P., Grygier, M., Wadhera, R. K., Mallen, C., Curzen, N., …Siudak, Z. (2024). Indirect impact of the war in Ukraine on primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in Poland. Polish Archives of Internal Medicine, 134(6), https://doi.org/10.20452/pamw.16737

Introduction: The Russian invasion of Ukraine in February 2022 resulted in displacement of approximately 12.5 million refugees to adjacent countries, including Poland, which may have strained health care service delivery. Objectives: Using the ST-... Read More about Indirect impact of the war in Ukraine on primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in Poland.

Clinical Significance of Coronary Arterial Dominance: A Review of the Literature. (2024)
Journal Article
Wu, B., Kheiwa, A., Swamy, P., Mamas, M. A., Tedford, R. J., Alasnag, M., …Abramov, D. (in press). Clinical Significance of Coronary Arterial Dominance: A Review of the Literature. Journal of the American Heart Association, 13(9), Article e032851. https://doi.org/10.1161/JAHA.123.032851

Coronary dominance describes the anatomic variation of coronary arterial supply, notably as it relates to perfusion of the inferior cardiac territories. Differences in the development and outcome in select disease states between coronary dominance pa... Read More about Clinical Significance of Coronary Arterial Dominance: A Review of the Literature..

Intravascular Imaging-Guided Versus Coronary Angiography-Guided Complex PCI: A Meta-analysis of Randomized Controlled Trials. (2024)
Journal Article
Hamed, M., Mohamed, S., Mahmoud, M., Kahan, J., Mohsen, A., Rahman, F., …Elbadawi, A. (in press). Intravascular Imaging-Guided Versus Coronary Angiography-Guided Complex PCI: A Meta-analysis of Randomized Controlled Trials. Cardiology and Therapy, 13(2), 379-399. https://doi.org/10.1007/s40119-024-00364-7

Trials evaluating the role of intravascular imaging in percutaneous coronary intervention (PCI) for complex coronary artery disease have yielded mixed results. This study aimed to compare the outcomes of intravascular imaging specifically intravascul... Read More about Intravascular Imaging-Guided Versus Coronary Angiography-Guided Complex PCI: A Meta-analysis of Randomized Controlled Trials..

Influence of Social Vulnerability Index on Medicare Beneficiaries’ Expenditures upon Discharge (2024)
Journal Article
Ibrahim, R., Lin, L., Sainbayar, E., Pham, H. N., Shahid, M., Le Cam, E., …Mamas, M. A. (in press). Influence of Social Vulnerability Index on Medicare Beneficiaries’ Expenditures upon Discharge. Journal of Investigative Medicine, https://doi.org/10.1177/10815589241247791

Medicare beneficiaries’ healthcare spending varies across geographical regions, influenced by availability of medical resources and institutional efficiency. We aimed to evaluate whether social vulnerability influences healthcare costs among Medicare... Read More about Influence of Social Vulnerability Index on Medicare Beneficiaries’ Expenditures upon Discharge.

Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome (2024)
Journal Article
Mohamed, M., Ghosh, A. K., Banerjee, A., & Mamas, M. (in press). Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome. Canadian Journal of Cardiology, 40(6), 1146-1153. https://doi.org/10.1016/j.cjca.2024.03.012

Cancer and acute coronary syndrome (ACS) are the leading causes of morbidity and mortality globally, with many shared risk factors between both conditions. There are several challenges to the management of patients with cancer prese... Read More about Socioeconomic and ethnic disparities in the process of care and outcomes among cancer patients with acute coronary syndrome.