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Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis (2023)
Journal Article
Sedhom, R., Elbadawi, A., Megaly, M., Athar, A., Bharadwaj, A. S., Prasad, V., …Elgendy, I. Y. (2023). Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis. European Heart Journal: Acute Cardiovascular Care, 12(4), 224-231. https://doi.org/10.1093/ehjacc/zuad004

Aims To examine the shot-term outcomes with catheter-directed thrombolysis (CDT) vs. catheter-directed embolectomy (CDE) for high-risk pulmonary embolism (PE). Methods and results The Nationwide Readmissions Database was utilized to identify hospital... Read More about Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis.

Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan. (2023)
Journal Article
Rashid, Mamas, & Dafaalla. (2023). Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan. ESC Heart Failure, https://doi.org/10.1002/ehf2.14290

AIMS: Prognosis for ST-segment elevation myocardial infarction (STEMI) is worse when heart failure is present on admission. Understanding clinical practice in different health systems can identify areas for quality improvement initiatives to improve... Read More about Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan..

Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases (2023)
Journal Article
Wanamaker, B. L., Shoaib, A., Seth, M., Sukul, D., Mamas, M. A., & Gurm, H. S. (2023). Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases. Catheterization and Cardiovascular Interventions, 101(3), 495-504. https://doi.org/10.1002/ccd.30567

BACKGROUND: International registry comparisons provide insight into regional differences in clinical practice patterns, procedural outcomes, and general trends in population health and resource utilization in percutaneous coronary intervention (PCI).... Read More about Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases.

The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome (2023)
Journal Article
Fu, C. E., Yong, J. N., Ng, C. H., Nah, B., Chew, N. W. S., Chin, Y. H., …Muthiah, M. (2023). The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome. Alimentary pharmacology & therapeutics, 57(9), 979-987. https://doi.org/10.1111/apt.17397

Background/Aims Metabolic syndrome (MetS) affects over one third of the US adult population. Despite its close association with non-alcoholic fatty liver disease (NAFLD), the traditional definition of MetS does not account for the presence of NAFLD.... Read More about The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome.

The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019 (2023)
Journal Article
Mamas. (2023). The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019. Metabolism, 141, Article 155402. https://doi.org/10.1016/j.metabol.2023.155402

Background: A significant proportion of premature deaths globally are related to metabolic diseases in young adults. We examined the global trends and mortality of metabolic diseases in individuals aged below 40 years using data from the Global Burde... Read More about The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019.

The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. (2023)
Journal Article
Mamas, M., Scourfield, A., Dale, C., Takhar, R., Carragher, R., Katsoulis, M., …Thygesen, J. (2023). The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nature Medicine, 219 - 225. https://doi.org/10.1038/s41591-022-02158-7

How the Coronavirus Disease 2019 (COVID-19) pandemic has affected prevention and management of cardiovascular disease (CVD) is not fully understood. In this study, we used medication data as a proxy for CVD management using routinely collected, de-id... Read More about The impact of the COVID-19 pandemic on cardiovascular disease prevention and management..

Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017 (2023)
Journal Article
Kinnaird, T., Gallagher, S., Farooq, V., Protty, M., Back, L., Devlin, P., …Curzen, N. (2023). Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017. Circulation: Cardiovascular Interventions, 16(1), Article e012350. https://doi.org/10.1161/CIRCINTERVENTIONS.122.012350

Background: Percutaneous coronary intervention (PCI) is increasingly used as a treatment option for unprotected left main stem artery (unprotected left main stem percutaneous intervention) disease. However, whether patient outcomes have improved over... Read More about Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017.

Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study. (2023)
Journal Article
Carter, B., Jesenakova, S., Pana, T., Mohamed, M., Mamas, M., Myint, P., & Hollick, R. (2023). Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study. Journal of Clinical Medicine, https://doi.org/10.3390/jcm12020462

Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder associated with increased stroke risk. Its association with stroke outcomes remains poorly understood. In this study, we aimed to compare the sex-specific SLE-associated acute s... Read More about Sex-Specific Outcomes of Acute Stroke in Patients with Systemic Lupus Erythematosus: A National Inpatient Sample Study..

Association between cancer, CHA2DS2VASc risk, and in-hospital ischaemic stroke in patients hospitalized for atrial fibrillation (2023)
Journal Article
Matetic, A., Mohamed, M. O., Essien, U. R., Guha, A., Elkaryoni, A., Elbadawi, A., …Mamas, M. A. (2023). Association between cancer, CHA2DS2VASc risk, and in-hospital ischaemic stroke in patients hospitalized for atrial fibrillation. European Heart Journal - Quality of Care and Clinical Outcomes, 9(8), 749-757. https://doi.org/10.1093/ehjqcco/qcac090

Background Atrial fibrillation (AF) is commonly encountered in cancer patients. We investigated the CHA2DS2VASc score, and its association with in-hospital ischaemic stroke in patients with cancer who were hospitalized for AF. Methods and results Usi... Read More about Association between cancer, CHA2DS2VASc risk, and in-hospital ischaemic stroke in patients hospitalized for atrial fibrillation.

Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019 (2022)
Journal Article
Wei, S., Miranda, J. J., Mamas, M. A., Zühlke, L. J., Kontopantelis, E., Thabane, L., & Van Spall, H. G. C. (2023). Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019. European Heart Journal - Quality of Care and Clinical Outcomes, 9(7), 662-672. https://doi.org/10.1093/ehjqcco/qcac088

Background Heart failure (HF) is a global epidemic. Objective To assess global sex differences in HF epidemiology across country income levels. Methods and results Using Global Burden of Disease (GBD) data from 204 countries and territories 1990–2019... Read More about Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019.

Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study. (2022)
Journal Article
Patel, R. V., Ravindran, M., Qiu, F., Manoragavan, R., Sud, M., Tam, D. Y., …Wijeysundera, H. C. (2023). Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study. Journal of the American Heart Association, 12(1), Article e028144. https://doi.org/10.1161/JAHA.122.028144

Background Transcatheter aortic valve replacement (TAVR)/intervention has become the standard of care for treatment of severe aortic stenosis across the spectrum of risk. There are socioeconomic disparities in access to TAVR. The impact of these disp... Read More about Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study..

Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes (2022)
Journal Article
Mamas. (2022). Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes. International Journal of Cardiology, 374, 12 - 19. https://doi.org/10.1016/j.ijcard.2022.12.035

Introduction Percutaneous coronary interventions (PCI) are often performed in multimorbid patients with heterogeneous characteristics and variable clinical outcomes. We aimed to identify distinct clinical phenotypes utilizing machine learning and exp... Read More about Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes.

Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry (2022)
Journal Article
Mamas. (2022). Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry. European Heart Journal, 5020-5032. https://doi.org/10.1093/eurheartj/ehac511

Background and Aims Postinfarction ventricular septal defect (PIVSD) is a mechanical complication of myocardial infarction (MI) with a poor prognosis. Surgical repair is the mainstay of treatment, although percutaneous closure is increasingly underta... Read More about Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry.

Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion. (2022)
Journal Article
Mamas, & Rashid. (2022). Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion. Cardiovascular Revascularization Medicine, 49, 34-41. https://doi.org/10.1016/j.carrev.2022.12.005

BACKGROUND: There are limited data around sex differences in the risk profile, treatments and outcomes of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) lesions in contemporary interventional practice. We investigated the i... Read More about Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion..

Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. (2022)
Journal Article
Mamas. (2022). Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. PloS one, e0276731 - ?. https://doi.org/10.1371/journal.pone.0276731

BACKGROUND: Asthma is a prevalent chronic respiratory condition and remains a common cause for hospitalization. However, contemporary data on asthma hospitalization rates, comorbidity burden, and in-hospital outcomes are lacking. METHODS: Survey-... Read More about Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study..