All Outputs (757)

Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study) (2022)
Journal Article
Mamas. (2022). Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study). American Journal of Cardiology, 186, 71 - 79. https://doi.org/10.1016/j.amjcard.2022.10.023

Female gender has been shown to be associated with worse clinical outcomes after percutaneous coronary intervention (PCI). However, the impact of gender on the clinical outcomes of complex PCI is still poorly understood. This study examined the diffe... Read More about Impact of Sex on Clinical Outcomes in Patients undergoing Complex Percutaneous Coronary Angioplasty (from the e-ULTIMASTER Study).

The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies. (2022)
Journal Article
Mamas, M. (2022). The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies. Nutrition Reviews, 2275 - 2287. https://doi.org/10.1093/nutrit/nuac034

CONTEXT AND OBJECTIVE: The impact of existing malnutrition on stroke outcomes is poorly recognised and treated. Evidence was systematically reviewed and quantified by meta-analysis. METHODS: MEDLINE, EMBASE and Web of Science were searched from incep... Read More about The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies..

Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. (2022)
Journal Article
Elbadawi, A., Sedhom, R., Gad, M., Hamed, M., Elwagdy, A., Barakat, A. F., …Jneid, H. (2022). Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. European Journal of Internal Medicine, 105, 38 - 45. https://doi.org/10.1016/j.ejim.2022.07.015

BACKGROUND: Randomized controlled trials (RCTs) investigating the optimal screening strategy for atrial fibrillation (AF) have yielded conflicting results. OBJECTIVE: To examine the comparative efficacy of different AF screening strategies in old... Read More about Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials..

Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry) (2022)
Journal Article
Mamas. (2022). Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry). American Journal of Cardiology, 1 - 7. https://doi.org/10.1016/j.amjcard.2022.07.039

QRS duration (QRSd) is ill-defined and under-researched as a prognosticator in patients with non–ST-segment myocardial infarction (NSTEMI). We analyzed 240,866 adult (=18 years) hospitalizations with non–ST-segment elevation myocardial infarction usi... Read More about Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry).

Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes (2022)
Journal Article
Mamas. (2022). Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes. Diabetes Care, 2737-2745. https://doi.org/10.2337/dc22-0894

OBJECTIVE Heart failure (HF) often develops in patients with diabetes and is recognized for its role in increased cardiovascular morbidity and mortality in this population. Most existing models predict risk in patients with prevalent rather than i... Read More about Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes.

Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. (2022)
Journal Article
Mamas. (2022). Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. https://doi.org/10.1080/14779072.2022.2138858

BACKGROUND: A significant proportion of the world's population lives with physical disability (PD) requiring healthcare services. Risk factors for cardiovascular disease (CVD) such as hypertension and diabetes are more prevalent among patients with P... Read More about Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States..

Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions (2022)
Journal Article
Bullock-Palmer, R. P., Bravo-Jaimes, K., Mamas, M. A., & Grines, C. L. (2022). Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions. European Cardiology Review, 17, https://doi.org/10.15420/ecr.2022.23

In the past few decades, the accelerated improvement in technology has allowed the development of new and effective coronary and structural heart disease interventions. There has been inequitable patient access to these advanced therapies and signifi... Read More about Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions.

Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model. (2022)
Journal Article
Moledina, S. M., Kontopantelis, E., & Mamas, M. (2022). Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model. European Heart Journal, 4212 - ?. https://doi.org/10.1093/eurheartj/ehac477

This commentary refers to ‘Ethnicity-dependent performance of the Global Registry of Acute Coronary Events risk score for prediction of non-ST-segment elevation myocardial infarction in-hospital mortality: nationwide cohort study’, by S.M. Moledina e... Read More about Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model..

Indirect effects of the first two years of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries (2022)
Journal Article
Mamas. (2022). Indirect effects of the first two years of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. https://doi.org/10.1101/2022.10.13.22281031

Background Although morbidity and mortality from COVID-19 have been widely reported, the indirect effects of the pandemic beyond 2020 on other major diseases and health service activity have not been well described. Methods Analyses used national adm... Read More about Indirect effects of the first two years of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries.

Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve Replacement: A Population-Level Study. (2022)
Journal Article
Marcus, G., Dahir, M., Qiu, F., Manoragavan, R., Austin, P. C., Roifman, I., …Wijeysundera, H. C. (2022). Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve Replacement: A Population-Level Study. https://doi.org/10.1016/j.cjca.2022.10.002

BACKGROUND: Wide geographic variation in access to transcatheter (TAVR) and surgical (SAVR) aortic valve replacement exists, but the impact of socioethnic factors on the geographic variation of AS management in Ontario, Canada, is unknown. METHODS: N... Read More about Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve Replacement: A Population-Level Study..

Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve A (2022)
Journal Article
Marcus, G., Dahir, M., Qiu, F., Manoragavan, R., Austin, P. C., Roifman, I., …Wijeysundera, H. C. (2023). Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve A. Canadian Journal of Cardiology, 39(1), 22-31. https://doi.org/10.1016/j.cjca.2022.10.0020828-282X

Background Wide geographic variation in access to transcatheter (TAVR) and surgical (SAVR) aortic valve replacement exists, but the impact of socioethnic factors on the geographic variation of AS management in Ontario, Canada, is unknown. Methods... Read More about Relationship of Neighbourhood Social Deprivation and Ethnicity on Access to Transcatheter and Surgical Aortic Valve A.

Impact of Left Ventricular End-Diastolic Pressure on the Outcomes of Patients Undergoing Percutaneous Coronary Intervention. (2022)
Journal Article
Mamas. (2022). Impact of Left Ventricular End-Diastolic Pressure on the Outcomes of Patients Undergoing Percutaneous Coronary Intervention. The American Journal of Cardiology, 107 - 114. https://doi.org/10.1016/j.amjcard.2022.09.007

Left ventricular end-diastolic pressure (LVEDP) is an important hemodynamic marker of left ventricular performance and affects coronary perfusion. We evaluated the association of LVEDP with patient outcomes after elective or urgent percutaneous coron... Read More about Impact of Left Ventricular End-Diastolic Pressure on the Outcomes of Patients Undergoing Percutaneous Coronary Intervention..

Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) (2022)
Journal Article
Aktaa, S., Batra, G., James, S. K., Blackman, D. J., Ludman, P. F., Mamas, M., …Gale, C. P. (2023). Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart). European Heart Journal - Quality of Care and Clinical Outcomes, 9(5), 529-536. https://doi.org/10.1093/ehjqcco/qcac063

Aims Standardized data definitions are necessary for the quantification of quality of care and patient outcomes in observational studies and randomised controlled trials (RCTs). The European Unified Registries for Heart Care Evaluation and Randomised... Read More about Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart).

Ethnic disparities in ST-segment myocardial infarction outcomes and processes of care in patients with and without standard modifiable cardiovascular risk factors: a nationwide cohort study (2022)
Journal Article
Mamas. (2022). Ethnic disparities in ST-segment myocardial infarction outcomes and processes of care in patients with and without standard modifiable cardiovascular risk factors: a nationwide cohort study. European Heart Journal, https://doi.org/10.1093/eurheartj/ehac544.1179

Background There is growing interest in patients presenting with ST-elevation myocardial infarction (STEMI) in the absence of `standard modifiable cardiovascular risk factors' (SMuRFs), which include current smoking, hypertension, diabetes and hyperc... Read More about Ethnic disparities in ST-segment myocardial infarction outcomes and processes of care in patients with and without standard modifiable cardiovascular risk factors: a nationwide cohort study.

Sex-based differences of the impact of aortic valve calcium score on mortality and post-procedural outcomes after trans-catheter aortic valve replacement (2022)
Journal Article
Mamas. (2022). Sex-based differences of the impact of aortic valve calcium score on mortality and post-procedural outcomes after trans-catheter aortic valve replacement. European Heart Journal, https://doi.org/10.1093/eurheartj/ehac544.134

Abstract Introduction Sex based differences exist in the presentation, outcomes, and management of cardiovascular diseases. Although aortic valve calcium (AVC) score has been postulated to be associated with post-procedural outcomes after transcathe... Read More about Sex-based differences of the impact of aortic valve calcium score on mortality and post-procedural outcomes after trans-catheter aortic valve replacement.

Comparing direct oral anticoagulants versus vitamin K antagonist in patients with atrial fibrillation after transcatheter aortic valve replacement: an updated meta-analysis (2022)
Journal Article
Mamas. (2022). Comparing direct oral anticoagulants versus vitamin K antagonist in patients with atrial fibrillation after transcatheter aortic valve replacement: an updated meta-analysis. European Heart Journal, https://doi.org/10.1093/eurheartj/ehac544.1631

Abstract Background Oral anticoagulation therapy is indicated for patients undergoing transcatheter aortic valve replacement (TAVR) with concomitant or new onset atrial fibrillation (AF). However the data on optimal anticoagulation regimen in this p... Read More about Comparing direct oral anticoagulants versus vitamin K antagonist in patients with atrial fibrillation after transcatheter aortic valve replacement: an updated meta-analysis.

Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3.4 million individuals (2022)
Journal Article
Mamas. (2022). Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3.4 million individuals. European Heart Journal, https://doi.org/10.1093/eurheartj/ehac544.528

Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide; confers an increased risk of adverse outcomes and once diagnosed most patients will require lifelong-treatment. Population-based studies of AF incidence ar... Read More about Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3.4 million individuals.

To compare efficacy and safety of direct oral anticoagulants in patients with concurrent atrial fibrillation and bioprosthetic heart valve repair or replacement: a systematic review and meta-analysis (2022)
Journal Article
Mamas. (2022). To compare efficacy and safety of direct oral anticoagulants in patients with concurrent atrial fibrillation and bioprosthetic heart valve repair or replacement: a systematic review and meta-analysis. European Heart Journal, https://doi.org/10.1093/eurheartj/ehac544.1630

Abstract Background Use of direct oral anticoagulants (DOACs) is contraindicated in patients with mechanical valves. However data on their use in patients with atrial fibrillation (AF) and bioprosthetic valves (BV) is still limited. Purpose To ass... Read More about To compare efficacy and safety of direct oral anticoagulants in patients with concurrent atrial fibrillation and bioprosthetic heart valve repair or replacement: a systematic review and meta-analysis.

Cardiovascular outcomes and trends of Transcatheter vs. Surgical aortic valve replacement among octogenarians with heart failure: A Propensity Matched national cohort analysis. (2022)
Journal Article
Mamas, & Rashid. (2022). Cardiovascular outcomes and trends of Transcatheter vs. Surgical aortic valve replacement among octogenarians with heart failure: A Propensity Matched national cohort analysis

Background: Heart failure (HF) is a complex clinical syndrome with symptoms and signs that result from any structural or functional impairment of ventricular filling or ejection of blood. Limited data is available regarding the in-hospital outcomes o... Read More about Cardiovascular outcomes and trends of Transcatheter vs. Surgical aortic valve replacement among octogenarians with heart failure: A Propensity Matched national cohort analysis..

Saphenous Vein Graft Intervention. (2022)
Journal Article
Bharadwaj, A. S., & Mamas, M. (2022). Saphenous Vein Graft Intervention. Interventional Cardiology Clinics, 383 - 391. https://doi.org/10.1016/j.iccl.2022.05.001

Even though saphenous vein grafts (SVGs) are the most commonly used surgical conduits, their long-term patency is limited by accelerated atherosclerosis often resulting in acute coronary syndrome or asymptomatic occlusion. SVG intervention is associa... Read More about Saphenous Vein Graft Intervention..