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Impact of Intracoronary Imaging‐Guided Percutaneous Coronary Intervention on Procedural Outcomes Among Complex Patient Groups (2022)
Journal Article
Mohamed, M. O., Kinnaird, T., Wijeysundera, H. C., Johnson, T. W., Zaman, S., Rashid, M., …Mamas, M. A. (2022). Impact of Intracoronary Imaging‐Guided Percutaneous Coronary Intervention on Procedural Outcomes Among Complex Patient Groups. Journal of the American Heart Association, 11(19), 1-17. https://doi.org/10.1161/jaha.122.026500

Background Intracoronary imaging (ICI) has been shown to improve survival after percutaneous coronary intervention (PCI). Whether this prognostic benefit is sustained across different indications remains unclear. Methods and Results All PCI procedure... Read More about Impact of Intracoronary Imaging‐Guided Percutaneous Coronary Intervention on Procedural Outcomes Among Complex Patient Groups.

Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management (2022)
Journal Article
Masiero, G., Paradies, V., Franzone, A., Bellini, B., De Biase, C., Karam, N., …Chieffo, A. (2022). Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management. Journal of the American Heart Association, 11(19), 1-15. https://doi.org/10.1161/jaha.121.025944

The impact of sex on pathophysiological processes, clinical presentation, treatment options, as well as outcomes of degenerative aortic stenosis remain poorly understood. Female patients are well represented in transfemoral aortic valve implantation... Read More about Sex-Specific Considerations in Degenerative Aortic Stenosis for Female-Tailored Transfemoral Aortic Valve Implantation Management.

Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs. (2022)
Journal Article
Mamas. (2022). Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs. Journal of Cardiovascular Computed Tomography, https://doi.org/10.1016/j.jcct.2022.09.005

BACKGROUND: FFRCT assesses the functional significance of lesions seen on CTCA, and may be a more efficient approach to chest pain evaluation. The FORECAST randomized trial found no significant difference in costs within the UK National Health Servic... Read More about Randomized comparison of chest pain evaluation with FFRCT or standard care: Factors determining US costs..

The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism. (2022)
Journal Article
Mamas. (2022). The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism. International Journal of Cardiology, 354-362. https://doi.org/10.1016/j.ijcard.2022.09.049

OBJECTIVES: To evaluate the clinical care provided to cancer patients hospitalized for acute pulmonary embolism (PE), as well as the association between type of cancer, in-hospital care, and clinical outcomes. METHODS: This study examined the in-... Read More about The Association Between Cancer Diagnosis, Care, and Outcomes in 1 Million Patients Hospitalized for Acute Pulmonary Embolism..

Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling (2022)
Journal Article
Sumaya, W., Mamas, M. A., & Bagur, R. (2022). Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling. Journal of the American Heart Association, 11(19), https://doi.org/10.1161/JAHA.122.027165

Objectives To evaluate the clinical care provided to cancer patients hospitalized for acute pulmonary embolism (PE), as well as the association between type of cancer, in-hospital care, and clinical outcomes. Methods This study examined the in-hos... Read More about Quantitative Flow Ratio and Virtual Percutaneous Coronary Intervention for Serial Coronary Stenoses: Attractive Technology, But Still Crawling.

Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention. (2022)
Journal Article
Bashar, H., Matetić, A., Curzen, N., & Mamas, M. A. (2022). Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention. Catheterization and Cardiovascular Interventions, 100(5), 737-746. https://doi.org/10.1002/ccd.30404

OBJECTIVES: Extracardiac vascular disease (ECVD) is increasingly recognized as a cardiovascular risk factor, but its association with outcomes after percutaneous coronary intervention (PCI) has not been well characterized. METHODS: Using the National... Read More about Impact of extracardiac vascular disease on outcomes of 1.4 million patients undergoing percutaneous coronary intervention..

Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study. (2022)
Journal Article
Mamas. (2022). Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study. Journal of Clinical Epidemiology, 176 - 184. https://doi.org/10.1016/j.jclinepi.2022.09.009

OBJECTIVES: In observational studies, researchers must select a method to control for confounding. Options include propensity score (PS) methods and regression. It remains unclear how dataset characteristics (size, overlap in PSs, and exposure preval... Read More about Logistic regression frequently outperformed propensity score methods, especially for large datasets: a simulation study..

Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS). (2022)
Journal Article
Mamas. (2022). Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS). Journal of Cardiovascular Computed Tomography, 17(1), 66 - 83. https://doi.org/10.1016/j.jcct.2022.09.002

Cardio-Oncology is a rapidly growing sub-specialty of medicine, however, there is very limited guidance on the use of cardiac CT (CCT) in the care of Cardio-Oncology patients. In order to fill in the existing gaps, this Expert Consensus statement com... Read More about Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT). Endorsed by the International Cardio-Oncology Society (ICOS)..

Emergency department cardiovascular disease encounters and associated mortality in patients with cancer: A study of 20.6 million records from the USA. (2022)
Journal Article
Mamas. (2022). Emergency department cardiovascular disease encounters and associated mortality in patients with cancer: A study of 20.6 million records from the USA. International Journal of Cardiology, 210 - 217. https://doi.org/10.1016/j.ijcard.2022.06.053

BACKGROUND: there is limited data on Emergency department (ED) cardiovascular disease (CVD) presentations and outcomes amongst cancer patients. OBJECTIVES: The present study aimed to describe the clinical characteristics, prevalence, and clinical out... Read More about Emergency department cardiovascular disease encounters and associated mortality in patients with cancer: A study of 20.6 million records from the USA..

Rates of Elective Percutaneous Coronary Intervention in England and Wales: Impact of COURAGE and ORBITA Trials (2022)
Journal Article
Rashid, M., Stevens, C., Wijeysundera, H. C., Curzen, N., Wah Khoo, C., Osama Mohamed, M., …Mamas, M. A. (2022). Rates of Elective Percutaneous Coronary Intervention in England and Wales: Impact of COURAGE and ORBITA Trials. Journal of the American Heart Association, 11(18), Article e025426. https://doi.org/10.1161/jaha.122.025426

Background There are limited data about how COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) and ORBITA (Objective Randomized Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina) tr... Read More about Rates of Elective Percutaneous Coronary Intervention in England and Wales: Impact of COURAGE and ORBITA Trials.

Paclitaxel drug-coated balloon-only angioplasty for de novo coronary artery disease in elective clinical practice (2022)
Journal Article
Merinopoulos, I., Gunawardena, T., Corballis, N., Bhalraam, U., Gilbert, T., Maart, C., …Eccleshall, S. C. (2023). Paclitaxel drug-coated balloon-only angioplasty for de novo coronary artery disease in elective clinical practice. Clinical Research in Cardiology, 112(9), 1186-1193. https://doi.org/10.1007/s00392-022-02106-y

Objective: We aimed to investigate the safety of drug-coated balloon (DCB)-only angioplasty compared to drug-eluting stent (DES), as part of routine clinical practice. Background: The recent BASKETSMALL2 trial demonstrated the safety and efficacy of... Read More about Paclitaxel drug-coated balloon-only angioplasty for de novo coronary artery disease in elective clinical practice.

Urban-rural disparities in diabetes-related mortality in the USA 1999-2019. (2022)
Journal Article
Mamas. (2022). Urban-rural disparities in diabetes-related mortality in the USA 1999-2019. Diabetologia, https://doi.org/10.1007/s00125-022-05785-4

AIMS/HYPOTHESIS: Our study aimed to examine the trends in diabetes-related mortality in urban and rural areas in the USA over the past two decades. METHODS: We examined the trends in diabetes-related mortality (as the underlying or a contributing cau... Read More about Urban-rural disparities in diabetes-related mortality in the USA 1999-2019..

Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States (2022)
Journal Article
Raisi‐Estabragh, Z., Kobo, O., Elbadawi, A., Velagapudi, P., Sharma, G., Bullock‐Palmer, R. P., …Mamas, M. A. (2022). Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States. Journal of the American Heart Association, 11(19), 1-19. https://doi.org/10.1161/JAHA.122.026432

Background We describe sex‐differential disease patterns and outcomes of >20.6 million cardiovascular emergency department encounters in the United States. Methods and Results We analyzed primary cardiovascular encounters from the Nationwide Emerg... Read More about Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States.

Ischemic Heart Disease in Young Women (2022)
Journal Article
Mamas. (2022). Ischemic Heart Disease in Young Women. Journal of the American College of Cardiology, 1014 - 1022. https://doi.org/10.1016/j.jacc.2022.01.057

The Cardiovascular Disease in Women Committee of the American College of Cardiology convened a working group to develop a consensus regarding the continuing rise of mortality rates in young women aged 35 to 54 years. Heart disease mortality rates in... Read More about Ischemic Heart Disease in Young Women.

Complex, high-risk percutaneous coronary intervention types, trends, and in-hospital outcomes among different age groups: An insight from a national registry. (2022)
Journal Article
Rashid, M., Shamkhani, W., & Mamas, M. (2022). Complex, high-risk percutaneous coronary intervention types, trends, and in-hospital outcomes among different age groups: An insight from a national registry. Catheterization & Cardiovascular Interventions, 100(5), 711-720. https://doi.org/10.1002/ccd.30366

BACKGROUND: Complex, high-risk percutaneous coronary intervention (PCI) (CHiP) is increasingly being undertaken in octogenarians. However, limited data exist on CHiP types, trends, and outcomes in the octogenarian. METHODS: This is a retrospective co... Read More about Complex, high-risk percutaneous coronary intervention types, trends, and in-hospital outcomes among different age groups: An insight from a national registry..

Gender differences in mortality of hospitalised stroke patients. Systematic review and meta-analysis. (2022)
Journal Article
Mamas. (2022). Gender differences in mortality of hospitalised stroke patients. Systematic review and meta-analysis. Clinical Neurology and Neurosurgery, -. https://doi.org/10.1016/j.clineuro.2022.107359

OBJECTIVE: Gender differences in mortality after stroke remains unclear in the current literature. We therefore aimed to systematically review the gender differences in mortality up to five years after ischaemic (IS) or haemorrhagic stroke (HS) to ad... Read More about Gender differences in mortality of hospitalised stroke patients. Systematic review and meta-analysis..

Women Are Less Likely to Survive AMI Presenting With Out-of-Hospital Cardiac Arrest: A Nationwide Study. (2022)
Journal Article
Dafaalla, M., Rashid, M., Van Spall, H. G., Mehta, L., Parwani, P., Sharma, G., …Mamas, M. (2022). Women Are Less Likely to Survive AMI Presenting With Out-of-Hospital Cardiac Arrest: A Nationwide Study. Mayo Clinic Proceedings, 97(9), 1608 - 1618. https://doi.org/10.1016/j.mayocp.2022.06.011

OBJECTIVE: To assess the impact of patient's sex on outcomes and management of acute myocardial infarction (AMI) patients presenting with out-of-hospital cardiac arrest (OHCA). PATIENTS AND METHODS: We conducted a population-based retrospective cohor... Read More about Women Are Less Likely to Survive AMI Presenting With Out-of-Hospital Cardiac Arrest: A Nationwide Study..