Skip to main content

Research Repository

Advanced Search

All Outputs (757)

Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis. (2022)
Journal Article
Zghouzi, M., Osman, H., Ullah, W., Suleiman, A., Razvi, P., Abdalrazzak, M., …Chadi Alraies, M. (2022). Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis. Expert Review of Cardiovascular Therapy, 581 - 588. https://doi.org/10.1080/14779072.2022.2094368

BACKGROUND: Transcatheter aortic valve implantation (TAVI) has emerged as a safe and effective alternative to surgical replacement for tricuspid aortic valve (TAV) stenosis. However, utilization of TAVI for aortic stenosis in bicuspid aortic valve (B... Read More about Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis..

Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM) (2022)
Presentation / Conference
Mason, K., Bailey, J., Heron, N., Marshall, M., Achana, F., Chen, Y., …Jordan, K. (2022, July). Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM). Paper presented at SAPC ASM 2022 - UCLan 50th Annual Scientific Meeting, University of Central Lancashire, UK

Background: Patients with painful musculoskeletal conditions have an increased risk of developing cancer, but less is known about whether this impacts on the longer-term cancer prognosis. This study aims to determine whether patients with painful mus... Read More about Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM).

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records. (2022)
Journal Article
Mamas. (2022). COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records. The Lancet Digital Health, e542 - e557. https://doi.org/10.1016/S2589-7500%2822%2900091-7

BACKGROUND: Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes from nationwide linked e... Read More about COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records..

Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink. (2022)
Journal Article
Abhishek, A., Cipolletta, E., Nakafero, G., Avery, A. J., Mamas, M., & Tata, L. J. (2022). Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink. https://doi.org/10.1136/ard-2022-222668

Effect of Pneumococcal Vaccine on Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis (2022)
Journal Article
Mamas. (2022). Effect of Pneumococcal Vaccine on Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 3799 - 3799. https://doi.org/10.3390/jcm11133799

Various studies have suggested the possible cardiovascular (CV) protective effects of the pneumococcal vaccine (PV). Therefore, we conducted a meta-analysis to assess the association between recipients of PV with mortality and CV outcomes among patie... Read More about Effect of Pneumococcal Vaccine on Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis.

Variation in practice for out-of-hospital cardiac arrest treated with percutaneous coronary intervention in England and Wales. (2022)
Journal Article
Rashid, M., Kinnaird, T., Ludman, P., Keeble, T. R., Mamas, M., & Curzen, N. (2022). Variation in practice for out-of-hospital cardiac arrest treated with percutaneous coronary intervention in England and Wales. Catheterization and Cardiovascular Interventions, 100(3), 306-316. https://doi.org/10.1002/ccd.30316

Objectives We assessed the association between total center volume, operator volume, and out-of-hospital cardiac arrest (OHCA) percutaneous coronary intervention (PCI) volume. Background Variations between OHCA PCI volume, hospital total PCI, an... Read More about Variation in practice for out-of-hospital cardiac arrest treated with percutaneous coronary intervention in England and Wales..

IGFBP7 as a preoperative predictor of congestive acute kidney injury after cardiac surgery. (2022)
Journal Article
Mamas. (2022). IGFBP7 as a preoperative predictor of congestive acute kidney injury after cardiac surgery. Open Heart, https://doi.org/10.1136/openhrt-2022-002027

OBJECTIVE: Congestive acute kidney injury (c-AKI) refers to AKI in the presence of right ventricular failure (RVF) and is a highly morbid complication of cardiac surgery. However, treatment has traditionally been reactive rather than proactive due to... Read More about IGFBP7 as a preoperative predictor of congestive acute kidney injury after cardiac surgery..

A retrospective cohort study predicting and validating impact of the COVID-19 pandemic in individuals with chronic kidney disease (2022)
Journal Article
Dashtban, A., Mizani, M. A., Denaxas, S., Nitsch, D., Quint, J., Corbett, R., …Banerjee, A. (2022). A retrospective cohort study predicting and validating impact of the COVID-19 pandemic in individuals with chronic kidney disease. Kidney International, 102(3), 652-660. https://doi.org/10.1016/j.kint.2022.05.015

Chronic kidney disease (CKD) is associated with increased risk of baseline mortality and severe COVID-19, but analyses across CKD stages, and comorbidities are lacking. In prevalent and incident CKD, we investigated comorbidities, baseline risk, COVI... Read More about A retrospective cohort study predicting and validating impact of the COVID-19 pandemic in individuals with chronic kidney disease.

Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis (2022)
Journal Article
Mamas, M., Kastora, S. L., Pana, T. A., Sarwar, Y., & Myint, P. K. (2022). Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis. Molecular Diagnosis and Therapy, 26, 369-382. https://doi.org/10.1007/s40291-022-00597-z

BACKGROUND AND OBJECTIVE: Breast cancer is the leading cause of cancer-related mortality amongst women. One of the most common chemotherapeutic agents used to treat breast cancer, anthracyclines, are associated with anthracycline-induced cardiotoxici... Read More about Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis.

Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality (2022)
Journal Article
Mamas, Stickels, C. P., Nadarajah, R., Gale, C. P., Jiang, H., Sharkey, K. J., …Erhun, F. (2022). Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality. BMJ Open, 12(6), Article ARTN e059309. https://doi.org/10.1136/bmjopen-2021-059309

OBJECTIVES: To provide estimates for how different treatment pathways for the management of severe aortic stenosis (AS) may affect National Health Service (NHS) England waiting list duration and associated mortality. DESIGN: We constructed a mathemat... Read More about Aortic stenosis post-COVID-19: a mathematical model on waiting lists and mortality.

Transcatheter Aortic Valve Implantation With and Without Resheathing and Repositioning: A Systematic Review and Meta-analysis (2022)
Journal Article
Moroni, F., Azzalini, L., Sondergaard, L., Attizzani, G. F., Garcia, S., Jneid, H., …Bagur, R. (2022). Transcatheter Aortic Valve Implantation With and Without Resheathing and Repositioning: A Systematic Review and Meta-analysis. Journal of the American Heart Association, 11(12), e024707 - ?. https://doi.org/10.1161/JAHA.121.024707

Background There is a concern that resheathing/repositioning of transcatheter heart valves during transcatheter aortic valve implantation (TAVI) may lead to an increased risk of periprocedural complications. We aimed to evaluate the short- and long-t... Read More about Transcatheter Aortic Valve Implantation With and Without Resheathing and Repositioning: A Systematic Review and Meta-analysis.

Real-world management and outcomes of 7 million patients with acute coronary syndrome according to clinical research trial enrolment status: a propensity matched analysis. (2022)
Journal Article
Matetic, A., Mohamed, M. O., Roberts, D. J., Rana, J. S., Chadi Alraies, M., Patel, B., …Mamas, M. A. (2022). Real-world management and outcomes of 7 million patients with acute coronary syndrome according to clinical research trial enrolment status: a propensity matched analysis. European Heart Journal - Quality of Care and Clinical Outcomes, 409 - 419. https://doi.org/10.1093/ehjqcco/qcab098

AIMS: We aimed to determine whether clinical outcomes and invasive care of acute coronary syndrome (ACS) patients participating in trials differed from those of non-participants, particularly including those who were trial eligible. METHODS AND RESUL... Read More about Real-world management and outcomes of 7 million patients with acute coronary syndrome according to clinical research trial enrolment status: a propensity matched analysis..

Turnpike Catheter failure, causes and mechanisms: Insights from the MAUDE database. (2022)
Journal Article
Mamas, Alhusain, R., Dayco, J., Awadelkarim, A., Almas, T., Halboni, A., …Alraies, M. C. (2022). Turnpike Catheter failure, causes and mechanisms: Insights from the MAUDE database. https://doi.org/10.1016/j.amsu.2022.103923

Background: The Turnpike catheters (Teleflex, Wayne, PA, USA) is a microcatheter that was approved by the Food and Drug Administration in November 2014 to be used to access discrete regions of the coronary and peripheral vasculature. Methods: The Man... Read More about Turnpike Catheter failure, causes and mechanisms: Insights from the MAUDE database..

Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort (2022)
Journal Article
Wu, Mamas, Kwapong, Y. A., Boakye, E., Wang, G., Hong, X., …Sharma, G. (2022). Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort. Journal of Cardiovascular Development and Disease, 9(6), Article ARTN 179. https://doi.org/10.3390/jcdd9060179

Diabetes mellitus (pregestational (PDM) and gestational (GDM)) is associated with adverse pregnancy outcomes (APOs). However, studies exploring the association of APOs with maternal glycemia among women without PDM/GDM are limited. We utilized data f... Read More about Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort.

Design and evaluation of an interactive quality dashboard for national clinical audit data: a realist evaluation (2022)
Journal Article
Randell, R., Alvarado, N., Elshehaly, M., McVey, L., West, R. M., Doherty, P., …Ruddle, R. A. (2022). Design and evaluation of an interactive quality dashboard for national clinical audit data: a realist evaluation. Health and Social Care Delivery Research, 10(12), 1-156. https://doi.org/10.3310/WBKW4927

Background National audits aim to reduce variations in quality by stimulating quality improvement. However, varying provider engagement with audit data means that this is not being realised. Aim The aim of the study was to develop and evaluate a qual... Read More about Design and evaluation of an interactive quality dashboard for national clinical audit data: a realist evaluation.

A systematic review and meta-analysis of the impact of the left atrial appendage closure on left atrial function. (2022)
Journal Article
Mamas. (2022). A systematic review and meta-analysis of the impact of the left atrial appendage closure on left atrial function. Clinical Cardiology, 614 - 621. https://doi.org/10.1002/clc.23824

BACKGROUND: Left atrial (LA) appendage closure (LAAC) is effective in patients with atrial fibrillation who are not candidates for long-term anticoagulation. However, the impact of LAAC on LA function is unknown. The aim of this study is to evaluate... Read More about A systematic review and meta-analysis of the impact of the left atrial appendage closure on left atrial function..