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Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer (2023)
Journal Article
Mamas, M. A., Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., …Petersen, S. E. (2023). Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer. Heart, heartjnl-2022-321888. https://doi.org/10.1136/heartjnl-2022-321888

Objectives: To evaluate incident cardiovascular outcomes and imaging phenotypes in UK Biobank participants with previous cancer. Methods: Cancer and cardiovascular disease (CVD) diagnoses were ascertained using health record linkage. Participants wit... Read More about Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer.

Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study (2023)
Journal Article
Mason, K. J., Jordan, K. P., Heron, N., Edwards, J. J., Bailey, J., Achana, F. A., …Marshall, M. (2023). Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study. Musculoskeletal Care, 21(3), 749-762. https://doi.org/10.1002/msc.1748

OBJECTIVE: Musculoskeletal painful conditions are a risk factor for cardiovascular disease (CVD), but less is known about whether musculoskeletal pain also worsens prognosis from CVD. The objective was to determine whether patients with musculoskelet... Read More about Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study.

Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction (2023)
Journal Article
Sethupathi, P., Matetic, A., Bang, V., Myint, P. K., Rendon, I., Bagur, R., …Mamas, M. A. (2023). Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction. Cardiovascular Revascularization Medicine, 52, 16-22. https://doi.org/10.1016/j.carrev.2023.02.008

Background: Diabetes mellitus (DM) is an important risk factor for adverse outcomes following acute myocardial infarction (AMI), but large-scale studies investigating the differential impact of Type 1 DM (T1DM) and Type 2 DM (T2DM) on AMI outcomes ar... Read More about Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction.

Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet? (2023)
Journal Article
Averbuch, T., Mamas, M. A., & Van Spall, H. G. C. (in press). Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?. Jama Network Open, 6(2), e230577. https://doi.org/10.1001/jamanetworkopen.2023.0577

People with breast cancer are at increased risk of cardiovascular disease, myocardial injury, and heart failure (HF) due to underlying risk factors, a proinflammatory milieu, and cancer therapy–related cardiovascular toxic effects (CTR-CVT).1 Of the... Read More about Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?.

Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis (2023)
Journal Article
Sedhom, R., Dang, A. T., Elwagdy, A., Megaly, M., Elgendy, I. Y., Zahr, F., …Mamas, M. (2023). Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis. Catheterization and Cardiovascular Interventions, 101(4), 817-827. https://doi.org/10.1002/ccd.30597

AbstractBackgroundStudies comparing plug‐based (i.e., MANTA) with suture‐based (i.e., ProStar XL and ProGlide) vascular closure devices (VCDs) for large‐bore access closure after transcatheter aortic valve replacement (TAVR) have yielded mixed result... Read More about Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis.

Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019 (2023)
Journal Article
Chong, B., Jayabaskaran, J., Kong, G., Huak Chan, Y., Han Chin, Y., Goh, R., …Chew, N. W. (2023). Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019. EClinicalMedicine, 57, 3164-3178. https://doi.org/10.1016/j.eclinm.2023.101850

Aims The effect of the COVID-19 pandemic on care and outcomes across non-COVID-19 cardiovascular (CV) diseases is unknown. A systematic review and meta-analysis was performed to quantify the effect and investigate for variation by CV disease, geogra... Read More about Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019.

Coronary Physiologic Assessment Based on Angiography and Intracoronary Imaging (2023)
Journal Article
Reddy, M. S. H., Maddury, J., Mamas, M. A., Assa, H. V., & Kornowski, R. (2023). Coronary Physiologic Assessment Based on Angiography and Intracoronary Imaging. Indian Journal of Cardiovascular Disease in Women, 8(3), 200-210. https://doi.org/10.25259/ijcdw_15_2022

Intracoronary physiology testing has evolved as a promising diagnostic approach in the management of patients with coronary artery disease. The value of hyperemic translesional pressure ratios to estimate the functional relevance of coronary stenoses... Read More about Coronary Physiologic Assessment Based on Angiography and Intracoronary Imaging.

Meta-analysis of the effect of colchicine on C-reactive protein in patients with acute and chronic coronary syndromes (2023)
Journal Article
Alam, M., Kontopantelis, E., Mamas, M. A., Savinova, O. V., Jhaveri, A., Siddiqui, E., & Jhamnani, S. (2023). Meta-analysis of the effect of colchicine on C-reactive protein in patients with acute and chronic coronary syndromes. Coronary Artery Disease, 34(3), 210-215. https://doi.org/10.1097/mca.0000000000001220

Objective The anti-inflammatory drug colchicine has recently shown benefits in the prevention of major adverse cardiovascular events (MACE) in patients with the acute coronary syndrome (ACS) and chronic coronary syndromes (CCS). This meta-analysis... Read More about Meta-analysis of the effect of colchicine on C-reactive protein in patients with acute and chronic coronary syndromes.

Artificial intelligence-augmented analysis of contemporary procedural, mortality, and cost trends in carcinoid heart disease in a large national cohort with a focus on the “forgotten pulmonic valve” (2023)
Journal Article
Mamas. (2023). Artificial intelligence-augmented analysis of contemporary procedural, mortality, and cost trends in carcinoid heart disease in a large national cohort with a focus on the “forgotten pulmonic valve”. Frontiers in Cardiovascular Medicine, https://doi.org/10.3389/fcvm.2022.1071138

BackgroundCarcinoid heart disease is increasingly recognized and challenging to manage due to limited outcomes data. This is the largest known cohort study of valvular pathology, treatment (including pulmonary and tricuspid valve replacements [PVR an... Read More about Artificial intelligence-augmented analysis of contemporary procedural, mortality, and cost trends in carcinoid heart disease in a large national cohort with a focus on the “forgotten pulmonic valve”.

Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States. (2023)
Journal Article
Mamas, M. A., Kwapong, Y. A., Boakye, E., Khan, S. S., Honigberg, M. C., Martin, S. S., …Sharma, G. (2023). Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States. Journal of the American Heart Association, 12(3), Article e028332. https://doi.org/10.1161/jaha.122.028332

Background Depression is a nontraditional risk factor for cardiovascular disease (CVD). Data on the association of depression and poor mental health with CVD and suboptimal cardiovascular health (CVH) among young adults are limited. Methods and Resul... Read More about Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States..

Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis (2023)
Journal Article
Sedhom, R., Elbadawi, A., Megaly, M., Athar, A., Bharadwaj, A. S., Prasad, V., …Elgendy, I. Y. (2023). Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis. European Heart Journal: Acute Cardiovascular Care, 12(4), 224-231. https://doi.org/10.1093/ehjacc/zuad004

Aims To examine the shot-term outcomes with catheter-directed thrombolysis (CDT) vs. catheter-directed embolectomy (CDE) for high-risk pulmonary embolism (PE). Methods and results The Nationwide Readmissions Database was utilized to identify hospital... Read More about Outcomes with catheter-directed thrombolysis vs. catheter-directed embolectomy among patients with high-risk pulmonary embolism: a nationwide analysis.

Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan. (2023)
Journal Article
Rashid, Mamas, & Dafaalla. (2023). Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan. ESC Heart Failure, https://doi.org/10.1002/ehf2.14290

AIMS: Prognosis for ST-segment elevation myocardial infarction (STEMI) is worse when heart failure is present on admission. Understanding clinical practice in different health systems can identify areas for quality improvement initiatives to improve... Read More about Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan..

Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases (2023)
Journal Article
Wanamaker, B. L., Shoaib, A., Seth, M., Sukul, D., Mamas, M. A., & Gurm, H. S. (2023). Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases. Catheterization and Cardiovascular Interventions, 101(3), 495-504. https://doi.org/10.1002/ccd.30567

BACKGROUND: International registry comparisons provide insight into regional differences in clinical practice patterns, procedural outcomes, and general trends in population health and resource utilization in percutaneous coronary intervention (PCI).... Read More about Comparative analysis of percutaneous revascularization practice in the United States and the United Kingdom: Insights from the BMC2 and BCIS databases.

The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome (2023)
Journal Article
Fu, C. E., Yong, J. N., Ng, C. H., Nah, B., Chew, N. W. S., Chin, Y. H., …Muthiah, M. (2023). The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome. Alimentary pharmacology & therapeutics, 57(9), 979-987. https://doi.org/10.1111/apt.17397

Background/Aims Metabolic syndrome (MetS) affects over one third of the US adult population. Despite its close association with non-alcoholic fatty liver disease (NAFLD), the traditional definition of MetS does not account for the presence of NAFLD.... Read More about The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome.

The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019 (2023)
Journal Article
Mamas. (2023). The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019. Metabolism, 141, Article 155402. https://doi.org/10.1016/j.metabol.2023.155402

Background: A significant proportion of premature deaths globally are related to metabolic diseases in young adults. We examined the global trends and mortality of metabolic diseases in individuals aged below 40 years using data from the Global Burde... Read More about The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019.

The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. (2023)
Journal Article
Mamas, M., Scourfield, A., Dale, C., Takhar, R., Carragher, R., Katsoulis, M., …Thygesen, J. (2023). The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nature Medicine, 219 - 225. https://doi.org/10.1038/s41591-022-02158-7

How the Coronavirus Disease 2019 (COVID-19) pandemic has affected prevention and management of cardiovascular disease (CVD) is not fully understood. In this study, we used medication data as a proxy for CVD management using routinely collected, de-id... Read More about The impact of the COVID-19 pandemic on cardiovascular disease prevention and management..