All Outputs (143)

Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis (2016)
Journal Article
Mamas, Rashid, M., & Nolan, J. (2016). Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis. Heart, https://doi.org/10.1136/heartjnl-2015-308956

Abstract Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcome... Read More about Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis.

Habitual chocolate consumption and the risk of incident heart failure among healthy men and women (2016)
Journal Article
Mamas. (2016). Habitual chocolate consumption and the risk of incident heart failure among healthy men and women. Nutrition, Metabolism and Cardiovascular Diseases, 722-734. https://doi.org/10.1016/j.numecd.2016.01.003

Background: We aimed to examine the association between chocolate intake and the risk of incident heart failure in a UK general population. We conducted a systematic review and meta-analysis to quantify this association. Methods and results: We used... Read More about Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Habitual chocolate consumption and the risk of incident heart failure among healthy men and women (2016)
Journal Article
Mamas. (2016). Habitual chocolate consumption and the risk of incident heart failure among healthy men and women. Nutrition, Metabolism and Cardiovascular Diseases, 722 -734. https://doi.org/10.1016/j.numecd.2016.01.003

BACKGROUND: We aimed to examine the association between chocolate intake and the risk of incident heart failure in a UK general population. We conducted a systematic review and meta-analysis to quantify this association. METHODS AND RESULTS: We used... Read More about Habitual chocolate consumption and the risk of incident heart failure among healthy men and women.

Revascularization for Left Anterior Descending Artery Stenosis: A Review of the Evidence That Supports Practice (2016)
Journal Article
Mamas. (2016). Revascularization for Left Anterior Descending Artery Stenosis: A Review of the Evidence That Supports Practice. Cardiology in Review, https://doi.org/10.1097/CRD.0000000000000097

Disease of the proximal left anterior descending (LAD) artery is a common pathological finding often combined with disease in other coronary arteries. In this article we review specifically the evidence (and the guidelines arising from the data) for... Read More about Revascularization for Left Anterior Descending Artery Stenosis: A Review of the Evidence That Supports Practice.

Impact of operator volume for percutaneous coronary intervention (PCI) on clinical outcomes: what do the numbers say? (2016)
Journal Article
Mamas, M., & Rashid, M. (2016). Impact of operator volume for percutaneous coronary intervention (PCI) on clinical outcomes: what do the numbers say?. European Heart Journal, 16-22. https://doi.org/10.1093/ehjqcco/qcv030

The impact of operator and centre volume on clinical outcomes and quality of care has been of considerable debate in recent years in a number of surgical- and procedural-based specialities. A relationship between higher volumes at both the institutio... Read More about Impact of operator volume for percutaneous coronary intervention (PCI) on clinical outcomes: what do the numbers say?.

Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom (2015)
Journal Article
Mamas. (2015). Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom. European Heart Journal, 1312-1320. https://doi.org/10.1093/eurheartj/ehv631

The HORIZONS trial reported a survival advantage for bivalirudin over heparin-with-glycoprotein inhibitors (GPIs) in primary PCI for ST elevation myocardial infarction. This drove an international shift in clinical practice. Subsequent studies have p... Read More about Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom.

Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study (2015)
Journal Article
Mamas. (2015). Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study. European Heart Journal: Acute Cardiovascular Care, 191-198. https://doi.org/10.1177/2048872615623038

Objective: This study aims to study the prognostic impact of LV function on mortality and examine the effect of age on the prognostic value of left ventricular function. Methods: We examined the Myocardial Ischaemia National Audit Project (MINAP) reg... Read More about Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study.

Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis (2015)
Journal Article
Mamas. (2015). Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis. Diabetes Care, 2354-2369. https://doi.org/10.2337/dc15-1188

OBJECTIVE Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular... Read More about Long-term glycaemic variability and risk of adverse outcomes: a systematic review and meta-analysis.

Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues (2015)
Journal Article
Mamas, M., & Nolan, J. (2015). Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues. JACC: Cardiovascular Interventions, 1405-1409. https://doi.org/10.1016/j.jcin.2015.06.016

In the recently published MATRIX (Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX) trial, the use of transradial access (TRA) compared to transfemoral access (TFA) during percutaneous coronary i... Read More about Letter to the Editor Regarding “Efficacy of Radial Versus Femoral Access in the Acute Coronary Syndrome: Is it the operator or the operation that matters?” by Michel LeMay MD and colleagues.

Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database (2015)
Journal Article
Mamas. (2015). Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/CIRCINTERVENTIONS.117.005581

Background: The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients with a history of bypass surgery (PCI-CABG) is limited and the long-term effects unclear. Using a national PCI database, the i... Read More about Coronary perforation complicating percutaneous coronary intervention in patients with a history of coronary artery bypass surgery: an analysis of 309 perforation cases from the British Cardiovascular Intervention Society database.

Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies (2015)
Journal Article
Nolan, Rashid, & Mamas. (2015). Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies. Cardiovascular Revascularization Medicine, 484-490. https://doi.org/10.1016/j.carrev.2015.08.008

Objectives The aim of this study is to review the available literature on the efficacy and safety of agents used for prevention of RAS. Background Different vasodilator agents have been used to prevent radial artery spasm (RAS) in patients under... Read More about Intra-arterial vasodilators to prevent radial artery spasm: a systematic review and pooled analysis of clinical studies.

Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS) (2015)
Journal Article
Mamas, & Nolan. (2015). Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS). American Heart Journal, 164-172. https://doi.org/10.1016/j.ahj.2015.04.018

Background Gender is a strong predictor of periprocedural major bleeding complications after percutaneous coronary intervention (PCI). The access site represents an important site of such bleeding complications, which has driven adoption of the tran... Read More about Effect of access site, gender, and indication on clinical outcomes after percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society (BCIS).

Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). (2015)
Journal Article
Mamas. (2015). Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). American Journal of Cardiology, 364-371. https://doi.org/10.1016/j.amjcard.2015.04.047

Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT (2015)
Journal Article
Mamas. (2015). Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT. European Heart Journal - Cardiovascular Imaging, 521 - 530. https://doi.org/10.1093/ehjci/jeu295

AIMS: To examine the utility of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in the early diagnosis of cardiac implantable electronic device (CIED) generator pocket infection. METHODS AND RESULTS: A tot... Read More about Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT.

A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function (2015)
Book Chapter
Mamas. (2015). A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function. In Medinfo 2015: Proceedings of the 15th World Congress on Health and Biomedical Informatics (696-700). https://doi.org/10.3233/978-1-61499-564-7-696

We demonstrate the use of electronic records and repeated measures of risk factors therein, to enable deeper understanding of the relationship between the full longitudinal trajectory of risk factors and outcomes. To illustrate, dynamic mixed effect... Read More about A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function.

Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis (2014)
Journal Article
Mamas. (2014). Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis. Open Heart, e000092 -?. https://doi.org/10.1136/openhrt-2014-000092

OBJECTIVE: The objective of this study is to evaluate the efficacy and safety of renal denervation in patients with resistant hypertension. METHODS: We searched MEDLINE and EMBASE for studies that evaluated the use of catheter-based renal sympathetic... Read More about Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis.

Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study (2014)
Journal Article
Mamas. (2014). Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study. PloS one, e88577 -?. https://doi.org/10.1371/journal.pone.0088577

BACKGROUND: Contemporary data remains limited regarding mortality and major adverse cardiac events (MACE) outcomes in patients undergoing PCI for different manifestations of coronary artery disease. OBJECTIVES: We evaluated mortality and MACE outcome... Read More about Outcomes in patients with acute and stable coronary syndromes: insights from the prospective NOBORI-2 study.

Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis. (2014)
Journal Article
Mamas, M., & Nolan, J. (2014). Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis. Open Heart, e000021 -?. https://doi.org/10.1136/openhrt-2013-000021

OBJECTIVES: To examine the relationship between periprocedural bleeding complications and major adverse cardiovascular events (MACEs) and mortality outcomes following percutaneous coronary intervention (PCI) and study differences in the prognostic im... Read More about Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis..

Serum sphingolipids level as a novel potential marker for early detection of human myocardial ischaemic injury (2013)
Journal Article
Mamas. (2013). Serum sphingolipids level as a novel potential marker for early detection of human myocardial ischaemic injury. Frontiers in Physiology, 130 - ?. https://doi.org/10.3389/fphys.2013.00130

BACKGROUND: Ventricular tachyarrhythmias are the most common and often the first manifestation of coronary heart disease and lead to sudden cardiac death (SCD). Early detection/identification of acute myocardial ischaemic injury at risk for malignant... Read More about Serum sphingolipids level as a novel potential marker for early detection of human myocardial ischaemic injury.

Atrial fibrillation in heart failure: an innocent bystander? (2012)
Journal Article
Mamas. (2012). Atrial fibrillation in heart failure: an innocent bystander?. Current Cardiology Reviews, 273 - 280. https://doi.org/10.2174/157340312803760839

Heart failure (HF) and atrial fibrillation (AF) frequently coexist and each complicates the course of the other. The purpose of this review is to analyse the prognostic impact of AF in patients with HF and assess whether there is an advantage in targ... Read More about Atrial fibrillation in heart failure: an innocent bystander?.