All Outputs (3)

Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies (2021)
Journal Article
Unsworth-White, S. R., Kitchen, M. O., & Bryan, R. T. (2022). Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies. Future Oncology, 18(1), 105-115. https://doi.org/10.2217/fon-2021-0781

Supplies of intravesical Bacillus Calmette-Guérin (BCG), the first-line treatment for most intermediate- and high-risk non-muscle-invasive bladder cancers (NMIBC), have proven unreliable over the past decade. This review considers the evolution of BC... Read More about Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies.

93 Sexually Transmitted Infections Remain Under-Diagnosed and Under-Treated in Young Men Presenting with Acute Scrotal Pain (2021)
Journal Article
Thomas, M., Thursby, H., Kitchen, M., & Liu, S. (2021). 93 Sexually Transmitted Infections Remain Under-Diagnosed and Under-Treated in Young Men Presenting with Acute Scrotal Pain. British Journal of Surgery, 108(Supplement_2), Article ARTN znab134.364. https://doi.org/10.1093/bjs/znab134.364

Introduction Epididymitis or epididymo-orchitis causing acute scrotal pain in men ≤35 years is a common presentation to primary and secondary care.Most are caused by sexually-transmitted-infections in this age group. Failure to identify or treat STIs... Read More about 93 Sexually Transmitted Infections Remain Under-Diagnosed and Under-Treated in Young Men Presenting with Acute Scrotal Pain.

DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells (2021)
Journal Article
Kitchen. (2021). DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells. Cells, 1032 - 1032. https://doi.org/10.3390/cells10051032

The application of physiological oxygen (physoxia) concentrations is becoming increasingly commonplace within a mammalian stem cell culture. Human mesenchymal stem cells (hMSCs) attract widespread interest for clinical application due to their unique... Read More about DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells.