All Outputs (4)

The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins (2016)
Journal Article
Ball, M., Baron, A., Bradshaw, B., Dumeunier, R., O'Brien, M., & Thomas, E. J. The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins. Organic and Biomolecular Chemistry, 14(40), 9650-9681. https://doi.org/10.1039/c6ob01804a

The development of a synthesis of the C1–C16 fragment of bryostatins in which the key step is a stereoselective oxy-Michael reaction used to assemble the cis-2,6-disubstituted tetrahydropyran with the exocyclic alkene already installed, is described.... Read More about The evolution of a stereoselective synthesis of the C1–C16 fragment of bryostatins.

The continuous-flow synthesis of carbazate hydrazones using a simplified computer-vision controlled liquid-liquid extraction system (2016)
Journal Article
Mhembere, P., O'Brien, M., & Cooper, D. (2016). The continuous-flow synthesis of carbazate hydrazones using a simplified computer-vision controlled liquid-liquid extraction system. Tetrahedron Letters, 5188-5191. https://doi.org/10.1016/j.tetlet.2016.10.018

A computer-vision controlled liquid-liquid extraction system was used in the continuous-flow synthesis of a series of carbazate hydrazones. The system uses open-source software components (Python, OpenCV) and is simpler and potentially more economica... Read More about The continuous-flow synthesis of carbazate hydrazones using a simplified computer-vision controlled liquid-liquid extraction system.

Creating 3-Dimensional Molecular Models to Help Students Visualize Stereoselective Reaction Pathways (2016)
Journal Article
O'Brien. (2016). Creating 3-Dimensional Molecular Models to Help Students Visualize Stereoselective Reaction Pathways. Journal of Chemical Education, 1663 - 1666. https://doi.org/10.1021/acs.jchemed.6b00250

An approach to the creation of learning materials that aid the visualization of stereoselective reaction pathways is presented. Molecular editing software can be used to create models of various transition-state geometries. These 3-dimensional models... Read More about Creating 3-Dimensional Molecular Models to Help Students Visualize Stereoselective Reaction Pathways.

Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide (2016)
Journal Article
Cooper, D., & O'Brien, M. (2016). Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide. SYNLETT, 164 - 168. https://doi.org/10.1055/s-0035-1560975

Incorporating open-source software components (Python, OpenCV), a computer-vision system was used to control the interface level in a gravity-based inline liquid–liquid separation device. This was used in the continuous flow bromination of a series o... Read More about Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide.