All Outputs (2)

RACK-1 overexpression protects against goniothalamin-induced cell death (2009)
Journal Article
Inayat-Hussain, S., Wong, L., Chan, K., Rajab, N., Din, L., Harun, R., …Williams, G. (2009). RACK-1 overexpression protects against goniothalamin-induced cell death. Toxicology Letters, 191(2-3), 118-122. https://doi.org/10.1016/j.toxlet.2009.08.012

Goniothalamin, a styryllactone, has been shown to induce cytotoxicity via apoptosis in several tumor cell lines. In this study, we have examined the potential role of several genes, which were stably transfected into T-cell lines and which regulate a... Read More about RACK-1 overexpression protects against goniothalamin-induced cell death.

Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells (2009)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2009). Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells. Leukemia Research, 33(11), 1539-1551. https://doi.org/10.1016/j.leukres.2009.05.013

The control of T-cell survival is of overwhelming importance for preventing leukemia and lymphoma. The present report demonstrates that the serine/threonine protein phosphatase PP4 regulates the survival of both leukemic T-cells and untransformed hum... Read More about Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.