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All Outputs (12)

Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain (2023)
Journal Article
Gu, S. H., Miñarro, M., Feliu, C., Hugot, J., Forrester, N. L., Weaver, S. C., …Forrester, N. L. (2023). Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain. Viruses, 15(6), Article 1313. https://doi.org/10.3390/v15061313

The recent detection of both Nova virus (NVAV) and Bruges virus (BRGV) in European moles (Talpa europaea) in Belgium and Germany prompted a search for related hantaviruses in the Iberian mole (Talpa occidentalis). RNAlater®-preserved lung tissue from... Read More about Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain.

The potential future role of antiviral fabrics within healthcare systems (2023)
Journal Article
Morris, H., Forrester-Soto, N., & Ogrodnik, P. (in press). The potential future role of antiviral fabrics within healthcare systems. Journal of the Textile Institute, 115(3), 453-459. https://doi.org/10.1080/00405000.2023.2193278

Health care-associated infection is acquired by patients while receiving care and represents the most frequent adverse event with a prevalence internationally ranging from 5.7% to 19.1%. Whilst the role of textiles as a fomite in infection has been q... Read More about The potential future role of antiviral fabrics within healthcare systems.

Low-fidelity Venezuelan equine encephalitis virus polymerase mutants to improve live-attenuated vaccine safety and efficacy. (2018)
Journal Article
Forrester-Soto. (2018). Low-fidelity Venezuelan equine encephalitis virus polymerase mutants to improve live-attenuated vaccine safety and efficacy. Virus Evolution, vey004 - vey004. https://doi.org/10.1093/ve/vey004

During RNA virus replication, there is the potential to incorporate mutations that affect virulence or pathogenesis. For live-attenuated vaccines, this has implications for stability, as replication may result in mutations that either restore the wil... Read More about Low-fidelity Venezuelan equine encephalitis virus polymerase mutants to improve live-attenuated vaccine safety and efficacy..

Evolution and spread of Venezuelan equine encephalitis complex alphavirus in the Americas. (2017)
Journal Article
Forrester-Soto, Auguste, A., Dugan, V., Lin, D., Adams, A., Forrester, N., …Weaver, S. (2017). Evolution and spread of Venezuelan equine encephalitis complex alphavirus in the Americas. PLoS Neglected Tropical Diseases, https://doi.org/10.1371/journal.pntd.0005693

Venezuelan equine encephalitis (VEE) complex alphaviruses are important re-emerging arboviruses that cause life-threatening disease in equids during epizootics as well as spillover human infections. We conducted a comprehensive analysis of VEE comple... Read More about Evolution and spread of Venezuelan equine encephalitis complex alphavirus in the Americas..

Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity. (2016)
Journal Article
Forrester-Soto. (2016). Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity. Scientific reports, 35819 - 35819. https://doi.org/10.1038/srep35819

The trade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between vertebrate and invertebrate hosts presents significant constraints on genetic change of arboviruses. Studying these constraints in mosquito-borne vir... Read More about Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity..

Characterization of Genetic Variability of Venezuelan Equine Encephalitis Viruses. (2016)
Journal Article
Forrester-Soto. (2016). Characterization of Genetic Variability of Venezuelan Equine Encephalitis Viruses. PloS one, e0152604 - e0152604. https://doi.org/10.1371/journal.pone.0152604

Venezuelan equine encephalitis virus (VEEV) is a mosquito-borne alphavirus that has caused large outbreaks of severe illness in both horses and humans. New approaches are needed to rapidly infer the origin of a newly discovered VEEV strain, estimate... Read More about Characterization of Genetic Variability of Venezuelan Equine Encephalitis Viruses..

Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage. (2015)
Journal Article
Forrester-Soto. (2015). Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage. Frontiers in Microbiology, 1037 - 1037. https://doi.org/10.3389/fmicb.2015.01037

Previous imported cases of Lassa fever (LF) into the United Kingdom from the Ivory Coast and Mali, as well as the detection of Lassa virus (LASV) among the Mastomys natalensis population within Mali has led to the suggestion that the endemic area for... Read More about Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage..

New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences. (2015)
Journal Article
Forrester-Soto. (2015). New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences. PloS one, e0117849 - e0117849. https://doi.org/10.1371/journal.pone.0117849

To generate the most diverse phylogenetic dataset for the flaviviruses to date, we determined the genomic sequences and phylogenetic relationships of 14 flaviviruses, of which 10 are primarily associated with Culex spp. mosquitoes. We analyze these d... Read More about New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences..

Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission. (2014)
Journal Article
Forrester-Soto. (2014). Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission. Viruses, 3991 - 4004. https://doi.org/10.3390/v6103991

The term arbovirus denotes viruses that are transmitted by arthropods, such as ticks, mosquitoes, and other biting arthropods. The infection of these vectors produces a certain set of evolutionary pressures on the virus; involving migration from the... Read More about Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission..

A novel live-attenuated vaccine candidate for mayaro Fever. (2014)
Journal Article
Forrester-Soto. (2014). A novel live-attenuated vaccine candidate for mayaro Fever. PLoS Neglected Tropical Diseases, e2969 - e2969. https://doi.org/10.1371/journal.pntd.0002969

Mayaro virus (MAYV) is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we ca... Read More about A novel live-attenuated vaccine candidate for mayaro Fever..

Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range. (2014)
Journal Article
Forrester-Soto. (2014). Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range. Virology Journal, 97 - 97. https://doi.org/10.1186/1743-422X-11-97

Background The family Mesoniviridae (order Nidovirales) comprises of a group of positive-sense, single-stranded RNA ([+]ssRNA) viruses isolated from mosquitoes. Findings Thirteen novel insect-specific virus isolates were obtained from mosquitoes c... Read More about Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range..