All Outputs (12)

Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles (2017)
Journal Article
Boriachek, K., Islam, M. N., Möller, A., Salomon, C., Nguyen, N.-T., Hossain, M. A., Yamauchi, Y., & Shiddiky, M. J. (2017). Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles. Small, 14(6), Article 1702153. https://doi.org/10.1002/smll.201702153

Exosomes are nanoscale (≈30–150 nm) extracellular vesicles of endocytic origin that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific composition of proteins, lipids, RNA, and DNA and can work as cargo to trans... Read More about Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles.

Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose. (2017)
Journal Article
Tanaka, S., Valentino Kaneti, Y., Bhattacharjee, R., Islam, M. N., Nakahata, R., Abdullah, N., Yusa, S.-I., Nguyen, N.-T., Shiddiky, M. J., Yamauchi, Y., & Hossain, M. A. (2017). Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose. ACS applied materials & interfaces, 10(1), https://doi.org/10.1021/acsami.7b13835

Herein, we report the soft-templated preparation of mesoporous iron oxide using an asymmetric poly(styrene-b-acrylic acid-b-ethylene glycol) (PS-b-PAA-b-PEG) triblock copolymer. This polymer forms a micelle consisting of a PS core, a PAA shell, and a... Read More about Mesoporous Iron Oxide Synthesized Using Poly(styrene-b-acrylic acid-b-ethylene glycol) Block Copolymer Micelles as Templates for Colorimetric and Electrochemical Detection of Glucose..

Microalgae as a Sustainable Source of Nutraceuticals (2017)
Book Chapter
Islam, M. N., Alsenani, F., & M. Schenk, P. (2017). Microalgae as a Sustainable Source of Nutraceuticals. . Wiley. https://doi.org/10.1002/9781119048961.ch1

Microalgae have become a popular target in the research community and biotechnology industry based on findings that many microalgal strains are very good sources of various nutraceuticals, such as vitamins, carotenoids, polyunsaturated fatty acids (P... Read More about Microalgae as a Sustainable Source of Nutraceuticals.

Gold-Loaded Nanoporous Ferric Oxide Nanocubes with Peroxidase-Mimicking Activity for Electrocatalytic and Colorimetric Detection of Autoantibody (2017)
Journal Article
Kamal Masud, M., Yadav, S., Islam, N., Nguyen, N.-T., Salomon, C., Kline, R., Alamri, H. R., Alothman, Z. A., Yamauchi, Y., Hossain, S. A., & Shiddiky, M. J. A. (2017). Gold-Loaded Nanoporous Ferric Oxide Nanocubes with Peroxidase-Mimicking Activity for Electrocatalytic and Colorimetric Detection of Autoantibody. Analytical Chemistry, 89(20), 11005-11013. https://doi.org/10.1021/acs.analchem.7b02880

The enzyme-mimicking activity of iron oxide based nanostructures has provided a significant advantage in developing advanced molecular sensors for biomedical and environmental applications. Herein, we introduce the horseradish peroxidase (HRP)-like a... Read More about Gold-Loaded Nanoporous Ferric Oxide Nanocubes with Peroxidase-Mimicking Activity for Electrocatalytic and Colorimetric Detection of Autoantibody.

Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level. (2017)
Journal Article
Islam, M. N., Kamal Masud, M., Nguyen, N.-T., Gopalan, V., Alamri, H. R., Alothman, Z. A., Al Hossain, M. S., Yamauchi, Y., Lamd, A. K., & Shiddiky, M. J. (2017). Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level. Biosensors & bioelectronics, 101, 275-281. https://doi.org/10.1016/j.bios.2017.09.027

A crucial issue in microRNA (miRNA) detection is the lack of sensitive method capable of detecting the low levels of miRNA in RNA samples. Herein, we present a sensitive and specific method for the electrocatalytic detection of miR-107 using gold-loa... Read More about Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level..

A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples (2017)
Journal Article
Islam, M. N., Gopalan, V., Haque, M. H., Kamal Masud, M., Al Hossain, M. S., Yamauchi, Y., Nguyen, N.-T., King-Yin Lam, A., & Shiddiky, M. J. (2017). A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples. Biosensors and Bioelectronics, 98, 227-233. https://doi.org/10.1016/j.bios.2017.06.051

Despite having reliable and excellent diagnostic performances, the currently available messenger RNA (mRNA) detection methods mostly use enzymatic amplification steps of the target mRNA which is generally affected by the sample manipulations, amplifi... Read More about A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples.

RNA Biomarkers: Diagnostic and Prognostic Potentials and Recent Developments of Electrochemical Biosensors (2017)
Journal Article
Islam, M. N., Kamal Masud, M., Haque, M. H., Al Hossain, M. S., Yamauchi, Y., Nguyen, N.-T., & Shiddiky, M. J. (2017). RNA Biomarkers: Diagnostic and Prognostic Potentials and Recent Developments of Electrochemical Biosensors. Small Methods, 1(7), Article 1700131. https://doi.org/10.1002/smtd.201700131

Ribonucleic acids (RNAs) are considered as effective and minimally invasive biomarkers for disease diagnosis and prognosis due to their critical role in the regulation of different cellular processes. Over the past several years, the rapid progress i... Read More about RNA Biomarkers: Diagnostic and Prognostic Potentials and Recent Developments of Electrochemical Biosensors.

Quantum dot-based sensitive detection of disease specific exosome in serum (2017)
Journal Article
Boriachek, K., Islam, M. N., Gopalan, V., Lam, A. K., Nguyen, N.-T., & Shiddiky, M. J. (2017). Quantum dot-based sensitive detection of disease specific exosome in serum. Analyst, 2211-2219. https://doi.org/10.1039/c7an00672a

Tumor-derived exosomes have emerged as promising cancer biomarkers due to their unique composition and functions. Herein, we report a stripping voltammetric immunoassay for the electrochemical detection of disease-specific exosomes using quantum dots... Read More about Quantum dot-based sensitive detection of disease specific exosome in serum.

Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry (2017)
Journal Article
Haque, M. H., Gopalan, V., Islam, M. N., Kamal Masud, M., Bhattacharjee, R., Al Hossain, M. S., Nguyen, N.-T., Lam, A. K., & Shiddiky, M. J. (2017). Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry. Analytica Chimica Acta, 976(11 July 2017), 84-93. https://doi.org/10.1016/j.aca.2017.04.034

Development of simple and inexpensive method for the analysis of gene-specific DNA methylation is important for the diagnosis and prognosis of patients with cancer. Herein, we report a relatively simple and inexpensive electrochemical method for the... Read More about Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry.

Colorimetric and electrochemical quantification of global DNA methylation using a methyl cytosine-specific antibody (2017)
Journal Article
Haque, M. H., Bhattacharjee, R., Islam, M. N., Gopalan, V., Nguyen, N.-T., Lam, A. K., & Shiddiky, M. J. (2017). Colorimetric and electrochemical quantification of global DNA methylation using a methyl cytosine-specific antibody. Analyst, https://doi.org/10.1039/c7an00526a

We report a simple colorimetric (naked-eye) and electrochemical method for the rapid, sensitive and specific quantification of global methylation levels using only 25 ng of input DNA. Our approach utilises a three-step strategy; (i) initial adsorptio... Read More about Colorimetric and electrochemical quantification of global DNA methylation using a methyl cytosine-specific antibody.

An electrochemical method for sensitive and rapid detection of FAM134B protein in colon cancer samples. (2017)
Journal Article
Islam, F., Haque, M. H., Yadav, S., Islam, M. N., Gopalan, V., Nguyen, N.-T., Lam, A. K., & Shiddiky, M. J. (2017). An electrochemical method for sensitive and rapid detection of FAM134B protein in colon cancer samples. Scientific Reports, 7(133), https://doi.org/10.1038/s41598-017-00206-8

Despite the excellent diagnostic applications of the current conventional immunoassay methods such as ELISA, immunostaining and Western blot for FAM134B detection, they are laborious, expensive and required a long turnaround time. Here, we report an... Read More about An electrochemical method for sensitive and rapid detection of FAM134B protein in colon cancer samples..

Electrochemical biosensing strategies for DNA methylation analysis (2017)
Journal Article
Hossain, T., Mahmudunnabi, G., Kamal Masud, M., Islam, M. N., Ooi, L., Konstantinov, K., Al Hossain, M. S., Martinac, B., Alici, G., Nguyen, N.-T., & Shiddiky, M. J. (2017). Electrochemical biosensing strategies for DNA methylation analysis. Biosensors and Bioelectronics, 94, 63-73. https://doi.org/10.1016/j.bios.2017.02.026

DNA methylation is one of the key epigenetic modifications of DNA that results from the enzymatic addition of a methyl group at the fifth carbon of the cytosine base. It plays a crucial role in cellular development, genomic stability and gene express... Read More about Electrochemical biosensing strategies for DNA methylation analysis.