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Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial (2019)
Journal Article
Wu. (2019). Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial. The Lancet, 394(10204), 1181 - 1190. https://doi.org/10.1016/S0140-6736%2819%2931963-4

BACKGROUND: In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease progression needs to be balanced against infant complications. The aim of this trial was to determine whethe... Read More about Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.

Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics (2019)
Journal Article
Mamas, & Wu. (2019). Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics. Journal of Women's Health, 1037-1050. https://doi.org/10.1089/jwh.2018.7480

Globally, cardiovascular disease is the most common cause of mortality in women accounting for 1 in 3 deaths. There remains an under recognition of cardiovascular disease as well as a lack of awareness of risk in women. Promotion of cardiovascular di... Read More about Pregnancy as a Predictor of Maternal Cardiovascular Disease: The era of CardioObstetrics.

Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics (2019)
Journal Article
Mamas, & Wu. (2019). Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics. Journal of Women's Health, 1037 - 1050. https://doi.org/10.1089/jwh.2018.7480

Globally, cardiovascular disease (CVD) is the most common cause of mortality in women accounting for one in three deaths. There remains an under recognition of CVD as well as a lack of awareness of risk in women. Promotion of CVD prevention is essent... Read More about Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics.

Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies (2018)
Journal Article
Wu, P., Farrell, W., Haworth, K., Emes, R., Kitchen, M., Glossop, J., …Fryer, A. (2018). Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies. Epigenetics, 122-128. https://doi.org/10.1080/15592294.2016.1166321

Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450K array analysis to det... Read More about Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies.

Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care (2017)
Journal Article
Heald, A. H., Livingston, M., Holland, D., Robinson, J., Moreno, G. Y., Donnahey, G., …Fryer, A. A. (2018). Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care. International Journal of Clinical Practice, 72(1), Article ARTN e13046. https://doi.org/10.1111/ijcp.13046

Introduction Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine disorders affecting women of reproductive age. We examined the specific tests that are done in primary care to lead to the diagnosis of PCOS, and to support the diagno... Read More about Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care.

Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene (1998)
Journal Article
Shiau, A., Yang, H., Wu, P., & Wu, C. (1998). Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene. Gene Therapy, 5, 1571–1574. https://doi.org/10.1038/sj.gt.3300757

The E. coli cytosine deaminase (CD) provides a negative selection system for suicide gene therapy as CD transfectants are eliminated following 5-fluorocytosine (5FC) treatment. Here we report a positive selection system for the CD gene using 5-fluoro... Read More about Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene.

General practitioners' attitudes to psychiatric and medical illness (1998)
Journal Article
LAWRIE, S., MARTIN, K., McNEILL, G., DRIFE, J., CHRYSTIE, P., REID, A., …BALL, J. (1998). General practitioners' attitudes to psychiatric and medical illness. Psychological Medicine, 28(6), 1463 - 1467. https://doi.org/10.1017/s0033291798007004

Background. General practitioners are increasingly involved in the care of patients with long-term psychiatric disorders. We have previously reported that general practitioners are less willing to treat patients with schizophrenia than those without... Read More about General practitioners' attitudes to psychiatric and medical illness.