Skip to main content

Research Repository

Advanced Search

All Outputs (103)

Salt and Water Balance (2022)
Book Chapter
Tabinor, M., Lambie, M., & Davies, S. J. Salt and Water Balance. In Evidence-Based Nephrology, Second Edition (113-126). Wiley. https://doi.org/10.1002/9781119105954.ch46

Achieving salt and water balance is fundamental to optimizing fluid status, one of the key objectives of peritoneal dialysis (PD) treatment. The relative importance of salt and water management to patient outcomes was historically underestimated by e... Read More about Salt and Water Balance.

Genetic Determinants of Ultrafiltration With Peritoneal Dialysis (2022)
Presentation / Conference
Stanaway, I. B., Devuyst, O., Perl, J., Lambie, M., Morelle, J., Jarvik, G. P., …Mehrotra, R. (2022, November). Genetic Determinants of Ultrafiltration With Peritoneal Dialysis. Poster presented at Kidney Week, Orlando, Florida

The Bioimpedance Spectroscopy to Preserve Renal Output (BISTRO) Multicentre Randomised Controlled Trial: Quality of Life and Blood Pressure Outcomes (2022)
Presentation / Conference
Davies, S. J., Zanganeh, M., Solis-Trapala, I., Keane, D. F., Davenport, A., Wilkie, M. E., …Caskey, F. (2022, November). The Bioimpedance Spectroscopy to Preserve Renal Output (BISTRO) Multicentre Randomised Controlled Trial: Quality of Life and Blood Pressure Outcomes. Poster presented at ASN Kidney Week, Orlando, FL, USA

Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR (2022)
Journal Article
Lindley, E., Keane, D., Belcher, J., Fernandes Da Silva Jeffcoat, N., Davies, S., & trial investigators, B. (2022). Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR. Physiological Measurement, 43(8), Article 08NT01. https://doi.org/10.1088/1361-6579/ac80e8

OBJECTIVE: With growing recognition of the benefits of preserving residual kidney function (RKF) and use of incremental treatment regimes, the incentive to measure residual clearance in haemodialysis patients is increasing. Interdialytic urine collec... Read More about Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR.

Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle (2022)
Journal Article
Tshimologo, M., Allen, K., Coyle, D., Damery, S., Dikomitis, L., Fotheringham, J., …Davies, S. (2022). Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle. BMJ Open, e060922 - ?. https://doi.org/10.1136/bmjopen-2022-060922

INTRODUCTION: Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth understanding of centre cultural and organisatio... Read More about Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle.

Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study. (2022)
Journal Article
Lambie, M., Zhao, J., McCullough, K., Davies, S. J., Kawanishi, H., Johnson, D. W., …Perl, J. (2022). Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study. Clinical Journal of the American Society of Nephrology, 17(6), 861-871. https://doi.org/10.2215/CJN.16341221

Background and objectives Quantifying contemporary peritoneal dialysis time on therapy is important for patients and providers. We describe time on peritoneal dialysis in the context of outcomes of hemodialysis transfer, death, and kidney transplanta... Read More about Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study..

International Icodextrin Use and Association with Peritoneal Membrane Function, Fluid Removal, Patient and Technique Survival (2022)
Journal Article
Davies, S., Zhao, J., McCullough, K. P., Kim, Y., Wang, A. Y., Badve, S. V., …Perl, J. (2022). International Icodextrin Use and Association with Peritoneal Membrane Function, Fluid Removal, Patient and Technique Survival. Kidney360, 3(5), 872-882. https://doi.org/10.34067/kid.0006922021

Key Points There are important national and center differences in the prescription of icodextrin, with the United States a clear outlier; across all countries, icodextrin was more likely to be used if membrane function tests indicated reduced ultrafi... Read More about International Icodextrin Use and Association with Peritoneal Membrane Function, Fluid Removal, Patient and Technique Survival.

Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis (2022)
Journal Article
Davies, & Lambie. (2022). Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis. Kidney International Reports, https://doi.org/10.1016/j.ekir.2022.02.016

Introduction Transition to hemodialysis (HD) is a common outcome in peritoneal dialysis (PD), but the associated mortality risk is poorly understood. This study sought to identify rates of and risk factors for mortality after transitioning from PD t... Read More about Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis.

Spiritual well-being and its relationship with patient characteristics and other patient-reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS (2022)
Journal Article
Cheawchanwattana, A., Kanjanabuch, T., Puapatanakul, P., Narenpitak, S., Halue, G., Tungsanga, K., …Steering Groups, T. P. (2022). Spiritual well-being and its relationship with patient characteristics and other patient-reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS. Nephrology, 27(7), 621-631. https://doi.org/10.1111/nep.14034

Background Spiritual well-being (SWB), an individual's understanding of the meaning and purpose of life, may help patients with chronic or terminal illnesses cope with their diseases. This study aimed to assess SWB in patients on peritoneal dialysis... Read More about Spiritual well-being and its relationship with patient characteristics and other patient-reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS.

Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability (2021)
Journal Article
Davies. (2021). Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 533-541. https://doi.org/10.1177/08968608211049882

Background: In Europe, the number of elderly end-stage kidney disease patients is increasing. Few of those patients receive peritoneal dialysis (PD), as many cannot perform PD autonomously. Assisted PD programmes are available in most European coun... Read More about Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability.

AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. (2021)
Journal Article
Morelle, J., Marechal, C., Yu, Z., Debaix, H., Corre, T., Lambie, M., …Devuyst, O. (2021). AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. New England Journal of Medicine, 385, 1570 - 1580. https://doi.org/10.1056/NEJMoa2034279

BACKGROUND: Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in AQP1, the gene that encodes the archetypal water channel aquaporin-1, may contribut... Read More about AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis..

Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy (2021)
Presentation / Conference
Phannajit, J., Kanjanabuch, T., Ponpirul, K., Narenpitak, S., Puapatanakul, P., Johnson, D. W., …PDOPPS Steering Committee, O. B. O. T. (2021, August). Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy. Presented at 19th Asian Pacific Congress of Nephrology, Virtual Congress

Background: There are conflicting results concerning the survival differences between patients with and without hemodialysis (HD) transfer (HDT). Using the Peritoneal Dialysis (PD) Outcomes and Practice Patterns Study (PDOPPS), a prospective cohort s... Read More about Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy.

The Peritoneal Dialysis Outcomes and Practice Patterns Study (2021)
Book Chapter
Stallard, B., Johnson, D. W., Perl, J., & Davies, S. J. (2021). The Peritoneal Dialysis Outcomes and Practice Patterns Study. In Applied Peritoneal Dialysis (395-410). Springer. https://doi.org/10.1007/978-3-030-70897-9_28

Background: Peritoneal dialysis (PD) technique failure remains a significant barrier to improving the outcomes for PD patients and increasing the uptake of PD worldwide. The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) has been d... Read More about The Peritoneal Dialysis Outcomes and Practice Patterns Study.

Renal staffs' understanding of patients' experiences of transition from peritoneal dialysis to in-centre haemodialysis and their views on service improvement: A multi-site qualitative study in England and Australia. (2021)
Journal Article
Jones, J. E., Damery, S. L., Allen, K., Johnson, D. W., Lambie, M., Holvoet, E., & Davies, S. J. (2021). Renal staffs' understanding of patients' experiences of transition from peritoneal dialysis to in-centre haemodialysis and their views on service improvement: A multi-site qualitative study in England and Australia. PloS one, 15(7), Article e0254931. https://doi.org/10.1371/journal.pone.0254931

INTRODUCTION: Many studies have explored patients' experiences of dialysis and other treatments for kidney failure. This is the first qualitative multi-site international study of how staff perceive the process of a patient's transition from peritone... Read More about Renal staffs' understanding of patients' experiences of transition from peritoneal dialysis to in-centre haemodialysis and their views on service improvement: A multi-site qualitative study in England and Australia..

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis. (2021)
Journal Article
Davies, & Lambie. (2021). A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis. Kidney International, 1101-1111. https://doi.org/10.1016/j.kint.2021.05.037

Movement of solutes across the peritoneum allows for the use of peritoneal dialysis to treat kidney failure. However, there is a large inter-individual variability in the peritoneal solute transfer rate (PSTR). Here, we tested the hypothesis that com... Read More about A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis..

MO681PERITONEAL DIALYSIS TIME ON THERAPY AND REGIONAL DIFFERENCES IN DEATH, TRANSFER TO HEMODIALYSIS AND KIDNEY TRANSPLANTATION: RESULTS FROM THE PDOPPS (2021)
Journal Article
Lambie, & Davies. (2021). MO681PERITONEAL DIALYSIS TIME ON THERAPY AND REGIONAL DIFFERENCES IN DEATH, TRANSFER TO HEMODIALYSIS AND KIDNEY TRANSPLANTATION: RESULTS FROM THE PDOPPS. Nephrology Dialysis Transplantation,

Abstract Background and Aims Comparing and interpreting regional differences in peritoneal dialysis (PD) time on therapy needs to consider differences in the rates of permanent transfer to hemodialysis (HDT), death or kidney transplantation. Here we... Read More about MO681PERITONEAL DIALYSIS TIME ON THERAPY AND REGIONAL DIFFERENCES IN DEATH, TRANSFER TO HEMODIALYSIS AND KIDNEY TRANSPLANTATION: RESULTS FROM THE PDOPPS.

MO680INTERNATIONAL COMPARISONS OF ICODEXTRIN PRESCRIPTION PRACTICE AND ITS ASSOCIATION WITH FLUID REMOVAL, BLOOD PRESSURE, PATIENT AND TECHNIQUE SURVIVAL* (2021)
Journal Article
Davies. (2021). MO680INTERNATIONAL COMPARISONS OF ICODEXTRIN PRESCRIPTION PRACTICE AND ITS ASSOCIATION WITH FLUID REMOVAL, BLOOD PRESSURE, PATIENT AND TECHNIQUE SURVIVAL*. Nephrology Dialysis Transplantation, https://doi.org/10.1093/ndt/gfab101.002

Abstract Background and Aims Icodextrin is designed to maintain ultrafiltration during the long dwell, especially when there is a risk of increased fluid reabsorption (fast peritoneal solute transfer rate, PSTR), without the need for excessive use o... Read More about MO680INTERNATIONAL COMPARISONS OF ICODEXTRIN PRESCRIPTION PRACTICE AND ITS ASSOCIATION WITH FLUID REMOVAL, BLOOD PRESSURE, PATIENT AND TECHNIQUE SURVIVAL*.

Expanding Utilization of Home Dialysis: An Action Agenda From the First International Home Dialysis Roundtable (2021)
Journal Article
Davies. (2021). Expanding Utilization of Home Dialysis: An Action Agenda From the First International Home Dialysis Roundtable. KIDNEY MEDICINE, 635-643. https://doi.org/10.1016/j.xkme.2021.04.004

In a groundbreaking meeting, leading global kidney disease organizations came together in the fall of 2020 as an International Home Dialysis Roundtable (IHDR) to address strategies to increase access to and uptake of home dialysis, both peritoneal di... Read More about Expanding Utilization of Home Dialysis: An Action Agenda From the First International Home Dialysis Roundtable.

Outcome measures for technique survival reported in peritoneal dialysis: A systematic review. (2021)
Journal Article
Lambie, & Davies. (2021). Outcome measures for technique survival reported in peritoneal dialysis: A systematic review. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/0896860821989874

BACKGROUND: Peritoneal dialysis (PD) technique survival is an important outcome for patients, caregivers and health professionals, however, the definition and measures used for technique survival vary. We aimed to assess the scope and consistency of... Read More about Outcome measures for technique survival reported in peritoneal dialysis: A systematic review..