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All Outputs (133)

Raising the standard of trial registration, conduct, and reporting (2020)
Journal Article
Cho, Y., Davies, S. J., & Johnson, D. W. (2020). Raising the standard of trial registration, conduct, and reporting. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(2), 112-114. https://doi.org/10.1177/0896860820902009

Evidence-based medicine can be defined as the conscientious, explicit, judicious, and reasonable use of modern, best evidence in making decisions about the care of individual patients.1 A randomized controlled trial (RCT) serves as the gold standard... Read More about Raising the standard of trial registration, conduct, and reporting.

International Society for Peritoneal Dialysis practice recommendations: Prescribing high-quality goal-directed peritoneal dialysis (2020)
Journal Article
Brown, E. A., Blake, P. G., Boudville, N., Davies, S., de Arteaga, J., Dong, J., …Warady, B. (2020). International Society for Peritoneal Dialysis practice recommendations: Prescribing high-quality goal-directed peritoneal dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(3), 244- 253. https://doi.org/10.1177/0896860819895364

The International Society for Peritoneal Dialysis last published a guideline on prescribing peritoneal dialysis (PD) in 2006. This focused on clearance of toxins and used a measure of waste product removal by dialysis using urea as an example. This g... Read More about International Society for Peritoneal Dialysis practice recommendations: Prescribing high-quality goal-directed peritoneal dialysis.

Incremental peritoneal dialysis (2020)
Journal Article
Blake, P. G., Dong, J., & Davies, S. J. (2020). Incremental peritoneal dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(3), 320 - 326. https://doi.org/10.1177/0896860819895362

Incremental peritoneal dialysis (PD) has been variably defined. It involves taking advantage of the residual renal function that is usually present at initiation of dialysis to initially prescribe less onerous lower doses of PD while still achieving... Read More about Incremental peritoneal dialysis.

Accuracy of the estimation of V and the implications this has when applying Kt/Vurea for measuring dialysis dose in peritoneal dialysis (2020)
Journal Article
Davies, S., & Finkelstein, F. O. (2020). Accuracy of the estimation of V and the implications this has when applying Kt/Vurea for measuring dialysis dose in peritoneal dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(3), 261 - 269. https://doi.org/10.1177/0896860819893817

BACKGROUND: Current guidelines for the prescription of peritoneal dialysis dose rely on a single cut-off 'minimal' value of Kt/V. To apply this in the clinic, this requires an accurate estimation of V, the volume of urea distribution that equates to... Read More about Accuracy of the estimation of V and the implications this has when applying Kt/Vurea for measuring dialysis dose in peritoneal dialysis.

International comparison of peritoneal dialysis prescriptions from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) (2020)
Journal Article
Wang, A. Y., Zhao, J., Bieber, B., Kanjanabuch, T., Wilkie, M., Marshall, M. R., …Working Group, P. D. P. A. F. M. (2020). International comparison of peritoneal dialysis prescriptions from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(3), 310-319. https://doi.org/10.1177/0896860819895356

Background:
We describe peritoneal dialysis (PD) prescription variations among Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) participants on continuous ambulatory PD (CAPD) and automated PD (APD; n = 4657) from Australia/New Zeal... Read More about International comparison of peritoneal dialysis prescriptions from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).

Patients’ experiences of transitioning between different renal replacement therapy modalities: A qualitative study (2020)
Journal Article
Holvoet, E., Verhaeghe, S., Davies, S., Combes, G., François, K., Johnson, D., …Van Humbeeck, L. (2020). Patients’ experiences of transitioning between different renal replacement therapy modalities: A qualitative study. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 40(6), 548-555. https://doi.org/10.1177/0896860819896219

Background:
Different kidney replacement therapy modalities are available to manage end-stage kidney disease, such as home-based dialysis, in-center hemodialysis, and kidney transplantation. Although transitioning between modalities is common, data... Read More about Patients’ experiences of transitioning between different renal replacement therapy modalities: A qualitative study.

Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018) (2019)
Journal Article
Davies, & Lambie. (2019). Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018). Clinical Journal of the American Society of Nephrology, 909 - 909. https://doi.org/10.2215/CJN.02830319

Background and objectives: The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bio... Read More about Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018).

Increasing access to integrated ESKD care as part of universal health coverage. (2019)
Journal Article
Davies. (2019). Increasing access to integrated ESKD care as part of universal health coverage. Kidney International, S1 - S33. https://doi.org/10.1016/j.kint.2018.12.005

The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted a summit on integrated ESKD care, including 9... Read More about Increasing access to integrated ESKD care as part of universal health coverage..

Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death (2019)
Journal Article
Lambie, M., Teece, L., Johnson, D. W., Petrie, M., Mactier, R., Solis-Trapala, I., …Davies, S. J. (2019). Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death. Nephrology Dialysis Transplantation, 1585-1591. https://doi.org/10.1093/ndt/gfz034

Background
Risk of Encapsulating Peritoneal Sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate risk o... Read More about Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

International Variations in Peritoneal Dialysis Utilization and Implications for Practice (2019)
Journal Article
Davies. (2019). International Variations in Peritoneal Dialysis Utilization and Implications for Practice. American Journal of Kidney Diseases, https://doi.org/10.1053/j.ajkd.2018.12.033

In many countries, the use of peritoneal dialysis (PD) remains low despite arguments that support its greater use, including dialysis treatment away from hospital settings, avoidance of central venous catheters, and potential health economic advantag... Read More about International Variations in Peritoneal Dialysis Utilization and Implications for Practice.

Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients (2019)
Journal Article
Yu, Z., Lambie, M., Chess, J., Williams, A., Do, J., Topley, N., & Davies, S. J. (2019). Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients. Frontiers in Physiology, 10, 105 -105. https://doi.org/10.3389/fphys.2019.00105

It is not clear whether the association of increased peritoneal protein clearance with worse survival on PD is a consequence of either local or systemic inflammation or indicative of generalized endothelial dysfunction associated with comorbidity. To... Read More about Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients.

Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative (2019)
Journal Article
Chan, C., Combes, G., Davies, S., Finkelstein, F., Firanek, C., Gomez, R., …Van Biesen, W. (2019). Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 39(1), 4 -12. https://doi.org/10.3747/pdi.2017.00242

Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The "integrated care" model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such... Read More about Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.

Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility? (2018)
Journal Article
Davies. (2018). Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?. Kidney International, 1050 -1052. https://doi.org/10.1016/j.kint.2018.09.012

Peritoneal dialysis technique survival remains challenging due to peritonitis and long-term alterations to peritoneal membrane function and integrity. Up to now, the development of less bio-incompatible dialysis solutions have not had a major impact... Read More about Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?.

The use of bioimpedance spectroscopy to guide fluid management in patients receiving dialysis (2018)
Journal Article
Tabinor, M., & Davies, S. (2018). The use of bioimpedance spectroscopy to guide fluid management in patients receiving dialysis. Current Opinion in Nephrology and Hypertension, 27(6), 406-412. https://doi.org/10.1097/MNH.0000000000000445

PURPOSE OF REVIEW
To summarize the findings of recent trials and meta-analyses designed to determine whether bioimpedance spectroscopy adds value to the clinical assessment of fluid status in dialysis patients so as to achieve a normally hydrated we... Read More about The use of bioimpedance spectroscopy to guide fluid management in patients receiving dialysis.

Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport (2018)
Journal Article
Davies, & Lambie. (2018). Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport. Clinical Journal of the American Society of Nephrology, 1526-1533. https://doi.org/10.2215/%3FCJN.02380218

Background and objectives
The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bio... Read More about Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport.