All Outputs (4)

A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex. (2022)
Journal Article
Butcher, J., Sims, R., Ngum, N., Bazzari, A. H., Jenkins, S. I., King, M., …Glazewski. (2022). A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex. Frontiers in Cellular Neuroscience, 16, Article 905285. https://doi.org/10.3389/fncel.2022.905285

Changes to sensory experience result in plasticity of synapses in the cortex. This experience-dependent plasticity (EDP) is a fundamental property of the brain. Yet, while much is known about neuronal roles in EDP, very little is known about the role... Read More about A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex..

Time-course and mechanisms of homeostatic plasticity in layers 2/3 and 5 of the barrel cortex (2017)
Journal Article
Glazewski, S., Greenhill, S., & Fox, K. (2017). Time-course and mechanisms of homeostatic plasticity in layers 2/3 and 5 of the barrel cortex. Philosophical Transactions B: Biological Sciences, 372(1715), https://doi.org/10.1098/rstb.2016.0150

Recent studies have shown that ocular dominance plasticity in layer 2/3 of the visual cortex exhibits a form of homeostatic plasticity that is related to synaptic scaling and depends on TNFa. In this study, we tested whether a similar form of plastic... Read More about Time-course and mechanisms of homeostatic plasticity in layers 2/3 and 5 of the barrel cortex.

Astrocyte and Neuronal Plasticity in the Somatosensory System (2015)
Journal Article
Sims, R. E., Butcher, J. B., Rheinallt Parri, H., & Glazewski, S. (2015). Astrocyte and Neuronal Plasticity in the Somatosensory System. Neural Plasticity, 2015, Article 732014. https://doi.org/10.1155/2015/732014

Changing the whisker complement on a rodent’s snout can lead to two forms of experience-dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are somatotopically represented. One form, termed coding plasticity, concerns chang... Read More about Astrocyte and Neuronal Plasticity in the Somatosensory System.

Stimulus intensity determines experience-dependent modifications in neocortical neuron firing rates. (2015)
Journal Article
Glazewski, S., & Barth, A. L. (2015). Stimulus intensity determines experience-dependent modifications in neocortical neuron firing rates. European Journal of Neuroscience, 41(4), 410 - 419. https://doi.org/10.1111/ejn.12805

Although subthreshold inputs of neocortical sensory neurons are broadly tuned, the spiking output is more restricted. These subthreshold inputs provide a substrate for stimulus intensity-dependent changes their spiking output, as well as for experien... Read More about Stimulus intensity determines experience-dependent modifications in neocortical neuron firing rates..