All Outputs (10)

Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction (2023)
Journal Article
Dimmock, R. L., Rotherham, M., El Haj, A. J., & Yang, Y. (in press). Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction. Gels, 9(11), Article 915. https://doi.org/10.3390/gels9110915

In the biomedical field, there is a demand for the development of novel approaches for the investigation of optical epithelial anatomical features with biomimetic materials. These materials are not only required to replicate structures but also enabl... Read More about Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction.

Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation (2023)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Z., Yang, Y., & Yuan, C. (2023). Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation. Journal of Materials Science, 58, Article 15499–15512

Marine biofouling presents a significant challenge to the sustainable development of the maritime industry. Antimicrobial peptide (AMP) offers a promising strategy to combat biofouling. However, the inherent susceptibility of natural AMPs composed of... Read More about Antifouling performance of D-enantiomers-based peptide-modified aluminum alloy surfaces with enhanced stability against proteolytic degradation.

Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method (2023)
Journal Article
Wang, X., Cabrera, D., Yang, Y., & Telling, N. (in press). Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method. Frontiers in Nanotechnology, 5, Article 1214313. https://doi.org/10.3389/fnano.2023.1214313

Magnetic nanoparticles (MNPs) are promising as local heat generators for magnetic hyperthermia under AC magnetic fields. The heating efficacy of MNPs is determined by the AC hysteresis loop area, which in turn is affected by the dynamic magnetic prop... Read More about Probing magnetization dynamics of iron oxide nanoparticles using a point-probe magneto-optical method.

Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models (2023)
Journal Article
Ranjbar, J., Njoroge, W., Gibbins, J. M., Roach, P., Yang, Y., & Harper, A. G. S. (2023). Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models. Gels, 9(6), Article 477. https://doi.org/10.3390/gels9060477

Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here w... Read More about Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models.

Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties (2023)
Journal Article
Mason, J. H., Luo, L., Reinwald, Y., Taffetani, M., Hallas-Potts, A., Herrington, C. S., …Bagnaninchi, P. O. (2023). Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties. Communications Biology, 6(1), Article 543. https://doi.org/10.1038/s42003-023-04788-0

The role of the mechanical environment in defining tissue function, development and growth has been shown to be fundamental. Assessment of the changes in stiffness of tissue matrices at multiple scales has relied mostly on invasive and often speciali... Read More about Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties.

INVESTIGATION OF CELL AGGREGATE SIZE AND POTENTIAL BONE GROWTH WITH BONE CELL LINE AND HUMAN MESENCHYMAL STEM CELLS (2023)
Conference Proceeding
Deegan, A., Lawlor, L., Yang, X., & Yang, Y. (2023). INVESTIGATION OF CELL AGGREGATE SIZE AND POTENTIAL BONE GROWTH WITH BONE CELL LINE AND HUMAN MESENCHYMAL STEM CELLS. . https://doi.org/10.1302/1358-992x.2023.8.041

Our previous research has demonstrated that minor adjustments to in vitro cellular aggregation parameters, i.e. alterations to aggregate size, can influence temporal and spatial mineral depositions within maturing bone cell nodules. What remains uncl... Read More about INVESTIGATION OF CELL AGGREGATE SIZE AND POTENTIAL BONE GROWTH WITH BONE CELL LINE AND HUMAN MESENCHYMAL STEM CELLS.

Spectroscopic modalities for detection of biomaterial degradation through macrophage activation (2023)
Presentation / Conference
Yang, Y., Xie, B., & Kalokoh, I. (2023, March). Spectroscopic modalities for detection of biomaterial degradation through macrophage activation. Poster presented at TERMIS 2023 – European Chapter, Manchester Central Conference Centre Manchester, UK

Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts (2023)
Journal Article
Ceylan, S., Dimmock, R., & Yang, Y. (in press). Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts. Polymers, 15(7), 1653. https://doi.org/10.3390/polym15071653

Cryogel formation is an effective approach to produce porous scaffolds for tissue engineering. In this study, cryogelation was performed to produce boron-containing scaffolds for bone tissue engineering. A combination of the synthetic polymer, poly(v... Read More about Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts.

Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network (2023)
Journal Article
Wang, X., Yang, Y., & Mandal, B. (2023). Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network. AIP conference proceedings, 2562, Article ARTN 020009. https://doi.org/10.1063/5.0111909

As the deadliest type of skin cancer, melanoma has a high mortality rate and takes away thousands of lives in the UK every year. However, if detected at earlier stage, the survival rate largely increases. With the development of machine learning, man... Read More about Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network.

Enhanced antifouling properties of marine antimicrobial peptides by PEGylation. (2023)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Z., Yang, Y., & Yuan, C. (2023). Enhanced antifouling properties of marine antimicrobial peptides by PEGylation. Frontiers in Bioengineering and Biotechnology, 1124389 - ?. https://doi.org/10.3389/fbioe.2023.1124389

Covalent immobilisation of antimicrobial peptides (AMPs) on underwater surfaces to combat marine biofouling is of great interest as it is an efficient, broad-spectrum and environmentally friendly strategy. Similar to post-translational modifications... Read More about Enhanced antifouling properties of marine antimicrobial peptides by PEGylation..