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All Outputs (127)

Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts (2023)
Journal Article
Ceylan, S., Dimmock, R., & Yang, Y. (in press). Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts. Polymers, 15(7), 1653. https://doi.org/10.3390/polym15071653

Cryogel formation is an effective approach to produce porous scaffolds for tissue engineering. In this study, cryogelation was performed to produce boron-containing scaffolds for bone tissue engineering. A combination of the synthetic polymer, poly(v... Read More about Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts.

Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network (2023)
Presentation / Conference Contribution
Wang, X., Yang, Y., & Mandal, B. Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network. Presented at INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING (ICoBE 2021), Perlis, Malaysia

As the deadliest type of skin cancer, melanoma has a high mortality rate and takes away thousands of lives in the UK every year. However, if detected at earlier stage, the survival rate largely increases. With the development of machine learning, man... Read More about Automatic Detection of Skin Cancer Melanoma Using Transfer Learning in Deep Network.

Enhanced antifouling properties of marine antimicrobial peptides by PEGylation. (2023)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Z., Yang, Y., & Yuan, C. (2023). Enhanced antifouling properties of marine antimicrobial peptides by PEGylation. Frontiers in Bioengineering and Biotechnology, 1124389 - ?. https://doi.org/10.3389/fbioe.2023.1124389

Covalent immobilisation of antimicrobial peptides (AMPs) on underwater surfaces to combat marine biofouling is of great interest as it is an efficient, broad-spectrum and environmentally friendly strategy. Similar to post-translational modifications... Read More about Enhanced antifouling properties of marine antimicrobial peptides by PEGylation..

Research Progress of Antimicrobial Peptides in the Field of Marine Antifouling (2022)
Journal Article
Lou, T., Bai, X., He, X., Yang, Y., Yang, Z., & Yuan, C. (2022). Research Progress of Antimicrobial Peptides in the Field of Marine Antifouling. China Surface Engineering, 35(2), 1-11. https://doi.org/10.11933/j.issn.1007-9289.20210611001

Marine biofouling is still a problem that needs to be urgently solved. However, comprehensive studies and reports on the research progress of antimicrobial peptides in the field of marine antifouling remain scant. Three types of antimicrobial peptide... Read More about Research Progress of Antimicrobial Peptides in the Field of Marine Antifouling.

Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation (2022)
Journal Article
Ranjbar, J., Yang, Y., & Harper, A. (2022). Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation. Platelets, 34(1), https://doi.org/10.1080/09537104.2022.2153823

Thrombus formation is highly dependent upon the physico-chemical environment in which it is triggered. Our ability to understand how thrombus formation is initiated, regulated, and resolved in the human body is dependent upon our ability to replicat... Read More about Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation.

Detection of lipid efflux from foam cell models using a label-free infrared method (2022)
Journal Article
Xie, B., Njoroge, W., Dowling, L. M., Sulé-Suso, J., Cinque, G., & Yang, Y. (2022). Detection of lipid efflux from foam cell models using a label-free infrared method. Analyst, 147(23), 5372-5385. https://doi.org/10.1039/D2AN01041K

Cardiovascular diseases are still among the leading causes of mortality and morbidity worldwide. The build-up of fatty plaques in the arteries, leading to atherosclerosis, is the most common cause of cardiovascular diseases. The central player in ath... Read More about Detection of lipid efflux from foam cell models using a label-free infrared method.

Antifouling performance and mechanism analysis of marine peptide modified aluminum alloy surface (2022)
Journal Article
Lou, T., Bai, X., He, X., Liu, W., Yang, Y., & Yuan, C. (2022). Antifouling performance and mechanism analysis of marine peptide modified aluminum alloy surface. Surface and Coatings Technology, 445, 128742. https://doi.org/10.1016/j.surfcoat.2022.128742

Biofouling, the settlement of nuisance fouling organisms on underwater surfaces, seriously affects the performance of the ship and the development of the maritime industry. Using antimicrobial peptides to obtain antifouling performance is one of the... Read More about Antifouling performance and mechanism analysis of marine peptide modified aluminum alloy surface.

Hydrostatic pressure stimulates the osteogenesis and angiogenesis of MSCs/HUVECs co-culture on porous PLGA scaffolds (2022)
Journal Article
Shen, H.-X., Liu, J.-Z., Yan, X.-Q., Yang, H.-N., Hu, S.-Q., Yan, X.-L., Xu, T., El Haj, A. J., Yang, Y., & Lü, L.-X. (2022). Hydrostatic pressure stimulates the osteogenesis and angiogenesis of MSCs/HUVECs co-culture on porous PLGA scaffolds. Colloids and Surfaces B: Biointerfaces, 213, 112419. https://doi.org/10.1016/j.colsurfb.2022.112419

In native bone tissue regeneration, blood vessels, providing oxygen and nutrition for tissues, can promote the regeneration of bone and accelerate the repair of a defected area. In this study, Poly(D, L-lactic-co-glycolic acid) (PLGA) inverse opal sc... Read More about Hydrostatic pressure stimulates the osteogenesis and angiogenesis of MSCs/HUVECs co-culture on porous PLGA scaffolds.

In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis. (2022)
Journal Article
Kaur Sandhu, A., Yang, Y., & Li, W.-W. (2022). In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis. ACS Biomaterials Science and Engineering, 8(5), 1749-1762. https://doi.org/10.1021/acsbiomaterials.1c01307

Biomaterial-associated infection is difficult to detect and brings consequences that can lead to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form biofilms. Antimicrobial peptides (AMPs) can target and kill bacterial... Read More about In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis..

New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. (2022)
Journal Article
Yang, & Wu. (2022). New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Scientific reports, 12, Article 5109. https://doi.org/10.1038/s41598-022-09005-2

Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indenta... Read More about New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties..

New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties (2022)
Journal Article
Yang, & Wu. (2022). New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Scientific reports, 12, Article 5109. https://doi.org/10.1038/s41598-022-09005-2

Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indenta... Read More about New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties.

Time-dependent mechanical behaviour of the aortic chronic dissection flap (2022)
Journal Article
Panpho, P., Yang, Y., Davies, H. A., Nawaytou, O., Harky, A., Torella, F., Field, M., Madine, J., & Akhtar, R. (2022). Time-dependent mechanical behaviour of the aortic chronic dissection flap. Interactive Cardiovascular and Thoracic Surgery, 34(5), 892-901. https://doi.org/10.1093/icvts/ivac029

The transition of aortic dissection from acute to chronic is poorly understood. We examined time-dependent mechanical behaviour and biochemical properties of chronic dissection tissues.

Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review (2021)
Journal Article
Ng, C. Y., Chai, J. Y., Foo, J. B., Mohamad Yahaya, N. H., Yang, Y., Ng, M. H., & Law, J. X. (in press). Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review. International Journal of Nanomedicine, Volume 16, 6749-6781. https://doi.org/10.2147/ijn.s327059

Treatment of cartilage defects such as osteoarthritis (OA) and osteochondral defect (OCD) remains a huge clinical challenge in orthopedics. OA is one of the most common chronic health conditions and is mainly characterized by the degeneration of arti... Read More about Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review.

Proceedings of International Conference on Biomedical Engineering (2021)
Presentation / Conference
Yang, & Naire. (2021, September). Proceedings of International Conference on Biomedical Engineering. Presented at International Conference on Biomedical Engineering (ICoBE 2021), UniMAP, Malaysia (Virtual)

Aspiration thrombectomy is a life-saving interventional procedure to remove a blood clot from the brain of stroke patients. The pressure and blood flow dynamics during this procedure are crucial in determining the clinical outcomes. A mathematical mo... Read More about Proceedings of International Conference on Biomedical Engineering.

Molecular dynamics simulation of peptide attachment on Al-based surfaces (2021)
Journal Article
Lou, T., Bai, X., He, X., Yang, Y., & Yuan, C. (2021). Molecular dynamics simulation of peptide attachment on Al-based surfaces. Progress in Organic Coatings, 157, 106310. https://doi.org/10.1016/j.porgcoat.2021.106310

Biofouling is a serious problem for devices or facilities working in marine environment that needs to be solved. Modifying the contact surface with antimicrobial peptides is a promised technique to inhibit biofouling. However, the attachment behavior... Read More about Molecular dynamics simulation of peptide attachment on Al-based surfaces.

The Combination of Tissue-Engineered Blood Vessel Constructs and Parallel Flow Chamber Provides a Potential Alternative to In Vivo Drug Testing Models (2021)
Journal Article
Njoroge, W., Hernández Hernández, A. C., Idris Musa, F., Butler, R., Harper, A. G. S., & Yang, Y. (2021). The Combination of Tissue-Engineered Blood Vessel Constructs and Parallel Flow Chamber Provides a Potential Alternative to In Vivo Drug Testing Models. Pharmaceutics, 13(3), Article 340. https://doi.org/10.3390/pharmaceutics13030340

Cardiovascular disease is a major cause of death globally. This has led to significant efforts to develop new anti-thrombotic therapies or re-purpose existing drugs to treat cardiovascular diseases. Due to difficulties of obtaining healthy human bloo... Read More about The Combination of Tissue-Engineered Blood Vessel Constructs and Parallel Flow Chamber Provides a Potential Alternative to In Vivo Drug Testing Models.

Quantitative measurement of mechanical properties in wound healing processes in a corneal stroma model by using vibrational optical coherence elastography (OCE) (2021)
Journal Article
Yang. (2021). Quantitative measurement of mechanical properties in wound healing processes in a corneal stroma model by using vibrational optical coherence elastography (OCE). Biomedical Optics Express, 588 - 603. https://doi.org/10.1364/BOE.404096

Corneal wound healing, caused by frequent traumatic injury to the cornea and increasing numbers of refractive surgeries, has become a vital clinical problem. In the cornea, wound healing is an extremely complicated process. However, little is known a... Read More about Quantitative measurement of mechanical properties in wound healing processes in a corneal stroma model by using vibrational optical coherence elastography (OCE).