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Genetic and environmental factors associated with laboratory rearing affect survival and assortative mating but not overall mating success in Anopheles gambiae sensu stricto. (2013)
Journal Article
(2013). Genetic and environmental factors associated with laboratory rearing affect survival and assortative mating but not overall mating success in Anopheles gambiae sensu stricto. PloS one, e82631 - ?. https://doi.org/10.1371/journal.pone.0082631

Anopheles gambiae sensu stricto, the main vector of malaria in Africa, is characterized by its vast geographical range and complex population structure. Assortative mating amongst the reproductively isolated cryptic forms that co-occur in many areas... Read More about Genetic and environmental factors associated with laboratory rearing affect survival and assortative mating but not overall mating success in Anopheles gambiae sensu stricto..

Identification of differentially expressed proteins in sulfadiazine resistant and sensitive strains of Toxoplasma gondii using difference-gel electrophoresis (DIGE). (2013)
Journal Article
(2013). Identification of differentially expressed proteins in sulfadiazine resistant and sensitive strains of Toxoplasma gondii using difference-gel electrophoresis (DIGE). International Journal for Parasitology: Drugs and Drug Resistance, 35 - 44. https://doi.org/10.1016/j.ijpddr.2012.12.002

Treatment options for toxoplasmosis in humans are generally limited to the use of sulfonamide and/or pyrimethamine-based compounds. However, there is increasing evidence for clinical therapy failures in patients suggesting the existence of drug resis... Read More about Identification of differentially expressed proteins in sulfadiazine resistant and sensitive strains of Toxoplasma gondii using difference-gel electrophoresis (DIGE)..

Risk practices for animal and human anthrax in Bangladesh: an exploratory study (2013)
Journal Article
Islam, M., Hossain, M., Mikolon, A., Parveen, S., Khan, M., Haider, N., …Luby, S. (2013). Risk practices for animal and human anthrax in Bangladesh: an exploratory study. https://doi.org/10.3402/iee.v3i0.21356

From August 2009 to October 2010, International Centre for Diarrheal Disease Research, Bangladesh and the Institute of Epidemiology, Disease Control and Research together investigated 14 outbreaks of anthrax which included 140 animal and 273 human ca... Read More about Risk practices for animal and human anthrax in Bangladesh: an exploratory study.

Can mass trapping reduce thrips damage and is it economically viable?: management of the western flower thrips in strawberry (2013)
Journal Article
(2013). Can mass trapping reduce thrips damage and is it economically viable?: management of the western flower thrips in strawberry. PloS one, e80787. https://doi.org/10.1371/journal.pone.0080787

The western flower thrips Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) is a cosmopolitan, polyphagous insect pest that causes bronzing to fruit of strawberry (Fragaria x ananassa). The main aim of this study was to test whether mas... Read More about Can mass trapping reduce thrips damage and is it economically viable?: management of the western flower thrips in strawberry.

Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5 (2013)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2013). Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5. BioMed Research International, 2013, Article 358015. https://doi.org/10.1155/2013/358015

Nonsense-mediated decay is a key RNA surveillance mechanism responsible for the rapid degradation of mRNAs containing premature termination codons and hence prevents the synthesis of truncated proteins. More recently, it has been shown that nonsense-... Read More about Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5.

On the catalytic mechanism of polysaccharide lyases: evidence of His and Tyr involvement in heparin lysis by heparinase I and the role of Ca2+ (2013)
Journal Article
Córdula, C. R., Lima, M. A., Shinjo, S. K., Gesteira, T. F., Pol-Fachin, L., Coulson-Thomas, V. J., …Tersariol, I. L. S. (2013). On the catalytic mechanism of polysaccharide lyases: evidence of His and Tyr involvement in heparin lysis by heparinase I and the role of Ca2+. Molecular BioSystems, 10(1), 54-64. https://doi.org/10.1039/C3MB70370C

The structurally diverse polysaccharide lyase enzymes are distributed from plants to animals but share common catalytic mechanisms. One, heparinase I (F. heparinum), is employed in the production of the major anticoagulant drug, low molecular weight... Read More about On the catalytic mechanism of polysaccharide lyases: evidence of His and Tyr involvement in heparin lysis by heparinase I and the role of Ca2+.

Integrated transcriptomic and proteomic analysis of the global response of Wolbachia to doxycycline-induced stress. (2013)
Journal Article
(2013). Integrated transcriptomic and proteomic analysis of the global response of Wolbachia to doxycycline-induced stress. ISME Journal, 925 - 937. https://doi.org/10.1038/ismej.2013.192

The bacterium Wolbachia (order Rickettsiales), representing perhaps the most abundant vertically transmitted microbe worldwide, infects arthropods and filarial nematodes. In arthropods, Wolbachia can induce reproductive alterations and interfere with... Read More about Integrated transcriptomic and proteomic analysis of the global response of Wolbachia to doxycycline-induced stress..

"Wrong, but useful": negotiating uncertainty in infectious disease modelling. (2013)
Journal Article
(2013). "Wrong, but useful": negotiating uncertainty in infectious disease modelling. PloS one, e76277 - ?. https://doi.org/10.1371/journal.pone.0076277

For infectious disease dynamical models to inform policy for containment of infectious diseases the models must be able to predict; however, it is well recognised that such prediction will never be perfect. Nevertheless, the consensus is that althoug... Read More about "Wrong, but useful": negotiating uncertainty in infectious disease modelling..

The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels (2013)
Journal Article
(2013). The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels. Journal of General Physiology, 493 -505. https://doi.org/10.1085/jgp.201311068

Sound stimuli elicit movement of the stereocilia that make up the hair bundle of cochlear hair cells, putting tension on the tip links connecting the stereocilia and thereby opening mechanotransducer (MT) channels. Tmc1 and Tmc2, two members of the t... Read More about The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels.

Draft Genome Sequence of a Meningitic Isolate of Cronobacter sakazakii Clonal Complex 4, Strain 8399 (2013)
Journal Article
(2013). Draft Genome Sequence of a Meningitic Isolate of Cronobacter sakazakii Clonal Complex 4, Strain 8399. Genome Announcements, https://doi.org/10.1128/genomeA.00833-13

The Cronobacter sakazakii clonal lineage defined as clonal complex 4 (CC4), composed of nine sequence types, is associated with severe cases of neonatal meningitis. To date, only closely related C. sakazakii sequence type 4 (ST4) strains have been s... Read More about Draft Genome Sequence of a Meningitic Isolate of Cronobacter sakazakii Clonal Complex 4, Strain 8399.

Phanta: a non-fluorescent photochromic acceptor for pcFRET. (2013)
Journal Article
(2013). Phanta: a non-fluorescent photochromic acceptor for pcFRET. PloS one, e75835 - ?. https://doi.org/10.1371/journal.pone.0075835

We have developed an orange non-fluorescent photochromic protein (quantum yield, 0.003) we call Phanta that is useful as an acceptor in pcFRET applications. Phanta can be repeatedly inter-converted between the two absorbing states by alternate exposu... Read More about Phanta: a non-fluorescent photochromic acceptor for pcFRET..

Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti (2013)
Journal Article
(2013). Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti. Biology open BiO / Company of Biologists, 1192 -1202. https://doi.org/10.1242/bio.20135603

Dramatic structural changes in microtubules (MT) and the assembly of complicated intercellular connections are seen during the development of the cellular matrix of the sense organ for hearing, the organ of Corti. This report examines the expression... Read More about Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti.

Draft Genome Sequences of Three Newly Identified Species in the Genus Cronobacter, C. helveticus LMG23732T, C. pulveris LMG24059, and C. zurichensis LMG23730T (2013)
Journal Article
Masood. (2013). Draft Genome Sequences of Three Newly Identified Species in the Genus Cronobacter, C. helveticus LMG23732T, C. pulveris LMG24059, and C. zurichensis LMG23730T. Genome Announcements, https://doi.org/10.1128/genomeA.00783-13

Cronobacter helveticus, Cronobacter pulveris, and Cronobacter zurichensis are newly described species in the Cronobacter genus, which is associated with serious infections of neonates. This is the first report of draft genome sequences for these spe... Read More about Draft Genome Sequences of Three Newly Identified Species in the Genus Cronobacter, C. helveticus LMG23732T, C. pulveris LMG24059, and C. zurichensis LMG23730T.

Draft Genome Sequence of the Earliest Cronobacter sakazakii Sequence Type 4 Strain, NCIMB 8272 (2013)
Journal Article
Masood. (2013). Draft Genome Sequence of the Earliest Cronobacter sakazakii Sequence Type 4 Strain, NCIMB 8272. Genome Announcements, https://doi.org/10.1128/genomeA.00782-13

The Cronobacter sakazakii clonal lineage defined as sequence type 4 (ST4) is associated with severe cases of neonatal meningitis and persistence in powdered infant formula. For genome sequencing of the earliest deposited culture collection strain of... Read More about Draft Genome Sequence of the Earliest Cronobacter sakazakii Sequence Type 4 Strain, NCIMB 8272.

Imaging African trypanosomes (2013)
Journal Article
MacLean, L., Myburgh, E., Rodgers, J., & Price, H. (2013). Imaging African trypanosomes. Parasite immunology, 35(9-10), 283 -294. https://doi.org/10.1111/pim.12046

Trypanosoma brucei are extracellular kinetoplastid parasites transmitted by the blood-sucking tsetse fly. They are responsible for the fatal disease human African trypanosomiasis (HAT), also known as sleeping sickness. In late-stage infection, trypan... Read More about Imaging African trypanosomes.

Matrix-assisted laser desorption ionization--time of flight mass spectrometry: an emerging tool for the rapid identification of mosquito vectors. (2013)
Journal Article
(2013). Matrix-assisted laser desorption ionization--time of flight mass spectrometry: an emerging tool for the rapid identification of mosquito vectors. PloS one, e72380 - ?. https://doi.org/10.1371/journal.pone.0072380

BACKGROUND: The identification of mosquito vectors is typically based on morphological characteristics using morphological keys of determination, which requires entomological expertise and training. The use of protein profiling by matrix-assisted las... Read More about Matrix-assisted laser desorption ionization--time of flight mass spectrometry: an emerging tool for the rapid identification of mosquito vectors..

Contrasted Fitness Costs of Docking and Antibacterial Constructs in the EE and EVida3 Strains Validates Two-Phase Anopheles gambiae Genetic Transformation System (2013)
Journal Article
(2013). Contrasted Fitness Costs of Docking and Antibacterial Constructs in the EE and EVida3 Strains Validates Two-Phase Anopheles gambiae Genetic Transformation System. PloS one, e67364 -?. https://doi.org/10.1371/journal.pone.0067364

The deployment of transgenic mosquitoes carrying genes for refractoriness to malaria has long been seen as a futuristic scenario riddled with technical difficulties. The integration of anti-malarial effector genes and a gene-drive system into the mos... Read More about Contrasted Fitness Costs of Docking and Antibacterial Constructs in the EE and EVida3 Strains Validates Two-Phase Anopheles gambiae Genetic Transformation System.

Migratory Reed Warblers Need Intact Trigeminal Nerves to Correct for a 1,000 km Eastward Displacement (2013)
Journal Article
Kishkinev, D., Chernetsov, N., Heyers, D., & Mouritsen, H. (2013). Migratory Reed Warblers Need Intact Trigeminal Nerves to Correct for a 1,000 km Eastward Displacement. PloS one, https://doi.org/10.1371/journal.pone.0065847

Several studies have shown that experienced night-migratory songbirds can determine their position, but it has remained a mystery which cues and sensory mechanisms they use, in particular, those used to determine longitude (east-west position). One p... Read More about Migratory Reed Warblers Need Intact Trigeminal Nerves to Correct for a 1,000 km Eastward Displacement.

Sialic acid utilization by Cronobacter sakazakii (2013)
Journal Article
Masood. (2013). Sialic acid utilization by Cronobacter sakazakii. Microbial Informatics and Experimentation, 3 - 3. https://doi.org/10.1186/2042-5783-3-3

Background The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis a... Read More about Sialic acid utilization by Cronobacter sakazakii.