Skip to main content

Research Repository

Advanced Search

All Outputs (862)

A Double-Clock or Jetlag Mechanism is Unlikely to be Involved in Detection of East–West Displacements in a Long-Distance Avian Migrant (2010)
Journal Article
Kishkinev, D., Chernetsov, N., & Mouritsen, H. (2010). A Double-Clock or Jetlag Mechanism is Unlikely to be Involved in Detection of East–West Displacements in a Long-Distance Avian Migrant. Auk, 127(4), 773-780. https://doi.org/10.1525/auk.2010.10032

Migratory birds are known to be able to navigate—to determine their position on the globe and the direction toward their distant goal—even if they cannot perceive any information emanating from the goal. One hypothesis, that of true bicoordinate navi... Read More about A Double-Clock or Jetlag Mechanism is Unlikely to be Involved in Detection of East–West Displacements in a Long-Distance Avian Migrant.

Multiplex reactions for the molecular detection of predation on pest and nonpest invertebrates in agroecosystems (2010)
Journal Article
KING, R. A., MORENO-RIPOLL, R., AGUSTÍ, N., SHAYLER, S. P., BELL, J. R., BOHAN, D. A., & SYMONDSON, W. O. (2011). Multiplex reactions for the molecular detection of predation on pest and nonpest invertebrates in agroecosystems. Molecular Ecology Resources, 11(2), 370-373. https://doi.org/10.1111/j.1755-0998.2010.02913.x

Species- and group-specific PCR primers were developed to study predation on pest and nonpest invertebrate species by generalist carabid predators in agroecosystems. To ensure the amplification of degraded DNA in predator gut samples, amplicons were... Read More about Multiplex reactions for the molecular detection of predation on pest and nonpest invertebrates in agroecosystems.

Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5) (2010)
Journal Article
Mourtada-Maarabouni, M., Hasan, A. M., Farzaneh, F., & Williams, G. T. (2010). Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5). Molecular Pharmacology, 78(1), 19 - 28. https://doi.org/10.1124/mol.110.064055

BACKGROUND: Eosinophils are characteristic participants in allergic inflammation. The intracellular signalling mechanisms involved in the migration of eosinophils to sites of allergic inflammation are poorly understood. Chemotactic responses of eosin... Read More about Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5).

Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5) (2010)
Journal Article
Mourtada-Maarabouni, M., Hasan, A. M., Farzaneh, F., & Williams, G. T. (2010). Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5). Molecular Pharmacology, 78(1), 19-28. https://doi.org/10.1124/mol.110.064055

The central importance of the serine/threonine protein kinase mTOR (mammalian Target of Rapamycin) in the control of cell growth and proliferation is well established. However, our knowledge both of the upstream pathways controlling mTOR activity and... Read More about Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5).

Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor (2010)
Journal Article
Matar Hasan, A., Mourtada-Maarabouni, M., Hameed, M. S., Williams, G. T., & Dent, G. (2010). Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor. International Immunopharmacology, 10(9), 1017-1021. https://doi.org/10.1016/j.intimp.2010.05.014

Background Eosinophils are characteristic participants in allergic inflammation. The intracellular signalling mechanisms involved in the migration of eosinophils to sites of allergic inflammation are poorly understood. Chemotactic responses of eosin... Read More about Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor.

Prey choice by carabid beetles feeding on an earthworm community analysed using species- and lineage-specific PCR primers (2010)
Journal Article
KING, R. A., VAUGHAN, I. P., BELL, J. R., BOHAN, D. A., & SYMONDSON, W. O. (2010). Prey choice by carabid beetles feeding on an earthworm community analysed using species- and lineage-specific PCR primers. Molecular Ecology, 19(8), 1721-1732. https://doi.org/10.1111/j.1365-294X.2010.04602.x

The carabid beetle Pterostichus melanarius is a major natural enemy of pests, such as aphids and slugs in agricultural systems. Earthworms are a dominant non-pest component of the diet of P. melanarius which help sustain the beetles during periods wh... Read More about Prey choice by carabid beetles feeding on an earthworm community analysed using species- and lineage-specific PCR primers.

Synthetic sex pheromone attracts the leishmaniasis vector Lutzomyia longipalpis to experimental chicken sheds treated with insecticide (2010)
Journal Article
(2010). Synthetic sex pheromone attracts the leishmaniasis vector Lutzomyia longipalpis to experimental chicken sheds treated with insecticide. Parasites and Vectors, 16 -?. https://doi.org/10.1186/1756-3305-3-16

Current strategies for controlling American visceral leishmaniasis (AVL) have been unable to prevent the spread of the disease across Brazil. With no effective vaccine and culling of infected dogs an unpopular and unsuccessful alternative, new tools... Read More about Synthetic sex pheromone attracts the leishmaniasis vector Lutzomyia longipalpis to experimental chicken sheds treated with insecticide.

Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model? (2010)
Journal Article
(2010). Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model?. Parasitology, 425 - 438. https://doi.org/10.1017/S0031182010000107

Since its use as a model to study metazoan parasite culture and in vitro development, the plerocercoid of the tapeworm, Ligula intestinalis, has served as a useful scientific tool to study a range of biological factors, particularly within its fish i... Read More about Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model?.

Rapid, learning-induced inhibitory synaptogenesis in murine barrel field (2010)
Journal Article
(2010). Rapid, learning-induced inhibitory synaptogenesis in murine barrel field. Journal of Neuroscience, 1176 - 1184. https://doi.org/10.1523/JNEUROSCI.2970-09.2010

The structure of neurons changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape, and dimensions of dendritic spines together with their synapses. However, precise data on these cha... Read More about Rapid, learning-induced inhibitory synaptogenesis in murine barrel field.

Effects of larval growth condition and water availability on desiccation resistance and its physiological basis in adult Anopheles gambiae sensu stricto (2010)
Journal Article
(2010). Effects of larval growth condition and water availability on desiccation resistance and its physiological basis in adult Anopheles gambiae sensu stricto. Malaria Journal, 225 -?. https://doi.org/10.1186/1475-2875-9-225

BACKGROUND: Natural populations of the malaria mosquito Anopheles gambiae s.s. are exposed to large seasonal and daily fluctuations in relative humidity and temperature, which makes coping with drought a crucial aspect of their ecology. METHODS: To b... Read More about Effects of larval growth condition and water availability on desiccation resistance and its physiological basis in adult Anopheles gambiae sensu stricto.

Hydric stress-dependent effects of Plasmodium falciparum infection on the survival of wild-caught Anopheles gambiae female mosquitoes. (2010)
Journal Article
(2010). Hydric stress-dependent effects of Plasmodium falciparum infection on the survival of wild-caught Anopheles gambiae female mosquitoes. Malaria Journal, 243 -?. https://doi.org/10.1186/1475-2875-9-243

BACKGROUND: Whether Plasmodium falciparum, the agent of human malaria responsible for over a million deaths per year, causes fitness costs in its mosquito vectors is a burning question that has not yet been adequately resolved. Understanding the evol... Read More about Hydric stress-dependent effects of Plasmodium falciparum infection on the survival of wild-caught Anopheles gambiae female mosquitoes..

Ecological immunology of mosquito-malaria interactions: Of non-natural versus natural model systems and their inferences (2009)
Journal Article
(2009). Ecological immunology of mosquito-malaria interactions: Of non-natural versus natural model systems and their inferences. Parasitology, 1935 -1942. https://doi.org/10.1017/S0031182009006234

There has been a recent shift in the literature on mosquito/Plasmodium interactions with an increasingly large number of theoretical and experimental studies focusing on their population biology and evolutionary processes. Ecological immunology of mo... Read More about Ecological immunology of mosquito-malaria interactions: Of non-natural versus natural model systems and their inferences.

Visual but not trigeminal mediation of magnetic compass information in a migratory bird (2009)
Journal Article
Zapka, M., Heyers, D., Hein, C. M., Engels, S., Schneider, N., Hans, J., …Mouritsen, H. (2009). Visual but not trigeminal mediation of magnetic compass information in a migratory bird. Nature, 461(7268), 1274-1277. https://doi.org/10.1038/nature08528

Magnetic compass information has a key role in bird orientation1,2,3, but the physiological mechanisms enabling birds to sense the Earth’s magnetic field remain one of the unresolved mysteries in biology2,4. Two biophysical mechanisms have become est... Read More about Visual but not trigeminal mediation of magnetic compass information in a migratory bird.

FAU regulates carboplatin resistance in ovarian cancer (2009)
Journal Article
(2010). FAU regulates carboplatin resistance in ovarian cancer. Genes, Chromosomes and Cancer, 49(1), 70-77. https://doi.org/10.1002/gcc.20721

The development of chemotherapy resistance by cancer cells is complex, using different mechanisms and pathways. The gene FAU (Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV)-associated ubiquitously expressed gene) was identified through function... Read More about FAU regulates carboplatin resistance in ovarian cancer.

RACK-1 overexpression protects against goniothalamin-induced cell death (2009)
Journal Article
Inayat-Hussain, S., Wong, L., Chan, K., Rajab, N., Din, L., Harun, R., …Williams, G. (2009). RACK-1 overexpression protects against goniothalamin-induced cell death. Toxicology Letters, 191(2-3), 118-122. https://doi.org/10.1016/j.toxlet.2009.08.012

Goniothalamin, a styryllactone, has been shown to induce cytotoxicity via apoptosis in several tumor cell lines. In this study, we have examined the potential role of several genes, which were stably transfected into T-cell lines and which regulate a... Read More about RACK-1 overexpression protects against goniothalamin-induced cell death.

Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells (2009)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2009). Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells. Leukemia Research, 33(11), 1539-1551. https://doi.org/10.1016/j.leukres.2009.05.013

The control of T-cell survival is of overwhelming importance for preventing leukemia and lymphoma. The present report demonstrates that the serine/threonine protein phosphatase PP4 regulates the survival of both leukemic T-cells and untransformed hum... Read More about Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.

PfeIK1, a eukaryotic initiation factor 2a kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation (2009)
Journal Article
Russo. (2009). PfeIK1, a eukaryotic initiation factor 2a kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation. Malaria Journal, 99 - 99. https://doi.org/10.1186/1475-2875-8-99

Background: Post-transcriptional control of gene expression is suspected to play an important role in malaria parasites. In yeast and metazoans, part of the stress response is mediated through phosphorylation of eukaryotic translation initiation fact... Read More about PfeIK1, a eukaryotic initiation factor 2a kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation.

Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus (2009)
Journal Article
Russo. (2009). Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus. Molecular Microbiology, 229 - 245. https://doi.org/10.1111/j.1365-2958.2009.06639.x

The Plasmodium falciparum genome encodes a single calpain. By generating P. falciparum clones expressing C-terminally tagged calpain, we localized this protein to the nucleolus. Pf_calpain possesses an unusual and long N-terminal domain in which we i... Read More about Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus.

Cooperative blood-feeding and the function and implications of feeding aggregations in the sand fly, Lutzomyia longipalpis (Diptera: Psychodidae) (2009)
Journal Article
(2009). Cooperative blood-feeding and the function and implications of feeding aggregations in the sand fly, Lutzomyia longipalpis (Diptera: Psychodidae). PLoS Neglected Tropical Diseases, e503 - ?. https://doi.org/10.1371/journal.pntd.0000503

Given the importance that the evolution of cooperation bears in evolutionary biology and the social sciences, extensive theoretical work has focused on identifying conditions that promote cooperation among individuals. In insects, cooperative or altr... Read More about Cooperative blood-feeding and the function and implications of feeding aggregations in the sand fly, Lutzomyia longipalpis (Diptera: Psychodidae).