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All Outputs (102)

Sources of prey availability data alter interpretation of outputs from prey choice null networks (2023)
Preprint / Working Paper
Cuff, J. P., Tercel, M. P., Windsor, F. M., Hawthorne, B. S., Hambäck, P. A., Bell, J. R., Symondson, W. O., & Vaughan, I. P. Sources of prey availability data alter interpretation of outputs from prey choice null networks

Null models provide an invaluable baseline against which to test fundamental ecological hypotheses and highlight patterns in foraging choices that cannot be explained by neutral processes or sampling artefacts. In this way, null models can advance ou... Read More about Sources of prey availability data alter interpretation of outputs from prey choice null networks.

Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming (2023)
Journal Article
Hyland, M., Mennan, C., Davies, R., Wilson, E., Tonge, D. P., Clayton, A., & Kehoe, O. (2023). Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming. Stem Cell Reviews and Reports, 19, 2391–2406. https://doi.org/10.1007/s12015-023-10586-2

Autoimmune conditions, such as rheumatoid arthritis, are characterised by a loss of immune tolerance, whereby the immune cells attack self-antigens causing pain and inflammation. These conditions can be brought into remission using pharmaceutical tre... Read More about Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming.

Parasite exchange and hybridisation at a wild-feral-domestic interface (2023)
Journal Article
Smith, W. J., Jezierski, M. T., Dunn, J. C., & Clegg, S. M. (2023). Parasite exchange and hybridisation at a wild-feral-domestic interface. International Journal for Parasitology, 53(14), 797-808. https://doi.org/10.1016/j.ijpara.2023.06.005

Interactions between wild, feral, and domestic animals are of economic and conservation significance. The pigeon Columba livia is a synanthropic species in a feral form, but it also includes the rare Rock Dove. Columba livia is an important player at... Read More about Parasite exchange and hybridisation at a wild-feral-domestic interface.

Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway (2023)
Journal Article
La Chapelle, M., Ruta, M., & Dunn, J. C. (2023). Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway. International Journal for Parasitology, 53(14), 787-796. https://doi.org/10.1016/j.ijpara.2023.06.002

Avian blood parasites, from the genera Plasmodium, Haemoproteus and Leucocytozoon, are predicted to alter their range and prevalence as global temperatures change, and host and vector ranges shift. Understanding large-scale patterns in the prevalence... Read More about Bird species with wider geographical ranges have higher blood parasite diversity but not prevalence across the African-Eurasian flyway.

Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. (2023)
Journal Article
Fezza, E., Roberts, J. M., Bruce, T. J. A., Walsh, L. E., Gaffney, M. T., Pope, T. W., Bruce, T. J. A., & Gaffney, M. T. (in press). Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues. Pest Management Science, 10.1002/ps.7665. https://doi.org/10.1002/ps.7665

Monitoring is an integral component of integrated pest management (IPM) programmes used to inform crop management decisions. Vine weevil, Otiorhynchus sulcatus F. (Coleoptera: Curculionidae), continues to cause economically significant losses in hort... Read More about Decoding attraction: improving vine weevil monitoring by exploiting key sensory cues..

Within- and between-host dynamics of producer and non-producer pathogens (2023)
Journal Article
Pike, V. L., Stevens, E. J., Griffin, A. S., & King, K. C. (2023). Within- and between-host dynamics of producer and non-producer pathogens. Parasitology, https://doi.org/10.1017/S0031182023000586

For infections to be maintained in a population, pathogens must compete to colonize hosts and transmit between them. We use an experimental approach to investigate within-and-between host dynamics using the pathogen Pseudomonas aeruginosa and the ani... Read More about Within- and between-host dynamics of producer and non-producer pathogens.

Food safety news events classification via a hierarchical transformer model (2023)
Journal Article
Xiong, S., Tian, W., Batra, V., Fan, X., Xi, L., Liu, H., & Liu, L. (2023). Food safety news events classification via a hierarchical transformer model. Heliyon, 9(7), Article e17806. https://doi.org/10.1016/j.heliyon.2023.e17806

In light of the significance of regulatory authorities and the rising demand for information disclosure, a vast amount of information on food safety news reports is readily accessible on the Internet. The extraction of such information for precise cl... Read More about Food safety news events classification via a hierarchical transformer model.

Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay (2023)
Thesis
Freakley, A. L. Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518051

Leishmaniasis is a neglected tropical disease associated with poverty, deprived socio-economic settings and population displacement, primarily due to conflict. The causative agent are species of Leishmania parasites that are transmitted by sand flies... Read More about Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay.

ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control (2023)
Thesis
Devlin, A. J. ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518613

Heparin is a member of the glycosaminoglycan (GAG) family of naturally occurring, polydisperse, linear polysaccharides. Heparin is a ubiquitous anticoagulant drug, a member of the WHO’s list of vital medicines and the second used drug by weight after... Read More about ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control.

The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner (2023)
Preprint / Working Paper
Shephard, M. T., Merkhan, M. M., Dale, T. P., & Forsyth, N. R. (2023). The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner

Background
Chronic disease states can share inflammation as an underlying pathology. Macrophages are associated with chronic inflammation; in general, M1 phenotype macrophage activity inhibits cell proliferation and causes tissue damage whilst M2 ma... Read More about The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner.

Timing of dense granule biogenesis in asexual malaria parasites (2023)
Preprint / Working Paper
Vallintine, T., & van Ooij, C. Timing of dense granule biogenesis in asexual malaria parasites

Malaria is an important infectious disease that continues to claim hundreds of thousands of lives annually. The disease is caused by infection of host erythrocytes by apicomplexan parasites of the genus Plasmodium. The parasite contains three differe... Read More about Timing of dense granule biogenesis in asexual malaria parasites.

Occurrence of tuberculosis among people exposed to cattle in Bangladesh (2023)
Journal Article
Sarkar, S., Haider, N., Islam, A., Hossain, M. B., Hossain, K., Mafij Uddin, M. K., Rahman, A., Ahmed, S. S. U., Banu, S., Rahim, Z., Heffelfinger, J. D., & Zeidner, N. (2023). Occurrence of tuberculosis among people exposed to cattle in Bangladesh. Veterinary Medicine and Science, 9(4), 1923-1933. https://doi.org/10.1002/vms3.1178

Background
Tuberculosis (TB) has been an important public health concern in Bangladesh. The most common cause of human TB is Mycobacterium tuberculosis, while bovine TB is caused by Mycobacterium bovis.

Objective
The objective of this study was... Read More about Occurrence of tuberculosis among people exposed to cattle in Bangladesh.

Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice (2023)
Journal Article
Cuff, J. P., Windsor, F. M., Tercel, M. P., Bell, J. R., Symondson, W. O., & Vaughan, I. P. (2023). Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice. Ecography, 2023(7), https://doi.org/10.1111/ecog.06737

Generalist invertebrate predators are sensitive to weather conditions, but the relationship between their trophic interactions and weather is poorly understood. This study investigates how weather affects the identity and frequency of spider trophic... Read More about Temporal variation in spider trophic interactions is explained by the influence of weather on prey communities, web building and prey choice.

Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans (2023)
Journal Article
Desbois, M., Pak, J. S., Opperman, K. J., Giles, A. C., & Grill, B. (2023). Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans. STAR Protocols, 4(2), https://doi.org/10.1016/j.xpro.2023.102262

We present an optimized protocol for in vivo affinity purification proteomics and biochemistry using the model organism C. elegans. We describe steps for target tagging, large-scale culture, affinity purification using a cryomill, mass spectrometry a... Read More about Optimized protocol for in vivo affinity purification proteomics and biochemistry using C. elegans.

Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain (2023)
Journal Article
Gu, S. H., Miñarro, M., Feliu, C., Hugot, J.-P., Forrester, N. L., Weaver, S. C., Yanagihara, R., Gu, S. H., Feliu, C., Hugot, J.-P., & Forrester, N. L. (2023). Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain. Viruses, 15(6), Article 1313. https://doi.org/10.3390/v15061313

The recent detection of both Nova virus (NVAV) and Bruges virus (BRGV) in European moles (Talpa europaea) in Belgium and Germany prompted a search for related hantaviruses in the Iberian mole (Talpa occidentalis). RNAlater®-preserved lung tissue from... Read More about Multiple Lineages of Hantaviruses Harbored by the Iberian Mole ( Talpa occidentalis ) in Spain.

Efficacy of selected botanical oils against the cassava whitefly (<i>Bemisia tabaci</i>) and their effects on its feeding behaviour (2023)
Journal Article
Amour, M., Wosula, E. N., Mrisho, L., Hoskins, C., Buss, D., Bruce, T., Stephano, F., & Legg, J. P. (2023). Efficacy of selected botanical oils against the cassava whitefly (Bemisia tabaci) and their effects on its feeding behaviour. Journal of Applied Entomology, 147(7), 473-485. https://doi.org/10.1111/jen.13128

The control of the whitefly Bemisia tabaci relies heavily on the use of synthetic insecticides. There is a need to develop alternative control strategies due to concerns about impact of these insecticides on the environmental and human health, and th... Read More about Efficacy of selected botanical oils against the cassava whitefly (<i>Bemisia tabaci</i>) and their effects on its feeding behaviour.