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Correction: Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes (2024)
Journal Article
Gamez, M., Elhegni, H. E., Fawaz, S., Ho Ho, K., Campbell, N. W., Copland, D. A., …Foster, R. R. (in press). Correction: Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes. Cardiovascular Diabetology, 23(1), 74. https://doi.org/10.1186/s12933-024-02170-w

Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1 (2024)
Journal Article
Mycroft-West, C. J., Abdelkarim, S., Duyvesteyn, H. M. E., Gandhi, N. S., Skidmore, M. A., Owens, R. J., & Wu, L. (in press). Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nature Communications, 15(1), Article 1326. https://doi.org/10.1038/s41467-024-45419-4

Heparan sulfate (HS) polysaccharides are major constituents of the extracellular matrix, which are involved in myriad structural and signaling processes. Mature HS polysaccharides contain complex, non-templated patterns of sulfation and epimerization... Read More about Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1.

Genome assembly and transcriptomic analysis to elucidate the ability of Nasonovia ribisnigri to break host plant resistance (2024)
Journal Article
Garrett, D., Teakle, G., Collier, R., Bell, J. R., Cerezo‐Medina, S., & Morales‐Hojas, R. (in press). Genome assembly and transcriptomic analysis to elucidate the ability of Nasonovia ribisnigri to break host plant resistance. Insect Molecular Biology, https://doi.org/10.1111/imb.12894

Aphid genomic resources enable the study of complex life history traits and provide information on vector biology, host adaption and speciation. The currant–lettuce aphid (Nasonovia ribisnigri (Hemiptera: Aphididae) (Mosley)) is a cosmopolitan pest o... Read More about Genome assembly and transcriptomic analysis to elucidate the ability of Nasonovia ribisnigri to break host plant resistance.

Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model. (2024)
Journal Article
Hardisty, G., Nicol, M. Q., Shaw, D. J., Bennet, I. D., Bryson, K., Ligertwood, Y., …Dutia, B. M. (2024). Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model. Journal of General Virology, 105(2), https://doi.org/10.1099/jgv.0.001962

Infections with persistent or latent viruses alter host immune homeostasis and have potential to affect the outcome of concomitant acute viral infections such as influenza A virus (IAV). Gammaherpesviruses establish life-long infections and require a... Read More about Latent gammaherpesvirus infection enhances type I IFN response and reduces virus spread in an influenza A virus co-infection model..

Sources of prey availability data alter interpretation of outputs from prey choice null networks (2024)
Journal Article
Cuff, J. P., Tercel, M. P., Windsor, F. M., Hawthorne, B. S., Hambäck, P. A., Bell, J. R., …Vaughan, I. P. (2024). Sources of prey availability data alter interpretation of outputs from prey choice null networks. Ecological Entomology, https://doi.org/10.1111/een.13315

Null models provide a valuable baseline against which fundamental ecological hypotheses can be tested and foraging choices that cannot be explained by neutral processes or sampling biases can be highlighted. In this way, null models can advance our u... Read More about Sources of prey availability data alter interpretation of outputs from prey choice null networks.

Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages (2024)
Journal Article
D’Amato, R., Taxiarchi, C., Galardini, M., Trusso, A., Minuz, R. L., Grilli, S., …Müller, R. (2024). Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages. Nature Communications, 15(1), Article 952. https://doi.org/10.1038/s41467-024-44907-x

CRISPR-based gene drives have the potential to spread within populations and are considered as promising vector control tools. A doublesex-targeting gene drive was able to suppress laboratory Anopheles mosquito populations in small and large cages, a... Read More about Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages.

Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes (2024)
Journal Article
Gamez, M., Elhegni, H. E., Fawaz, S., Ho, K. H., Campbell, N. W., Copland, D. A., …Foster, R. R. (in press). Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes. Cardiovascular Diabetology, 23(1), Article 50. https://doi.org/10.1186/s12933-024-02133-1

Background
Diabetes mellitus is a chronic disease which is detrimental to cardiovascular health, often leading to secondary microvascular complications, with huge global health implications. Therapeutic interventions that can be applied to multiple... Read More about Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes.

Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function (2024)
Journal Article
Chang, C., Banerjee, S. L., Soon Park, S., Lei Zhang, X., Cotnoir-White, D., Opperman, K. J., …Kania, A. (2024). Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function. eLife, 12, Article RP89176. https://doi.org/10.7554/eLife.89176.4

Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes during development and throughout adulthood. This versatility is likely facilitated by the ability of Eph receptors to signal through diverse cellular signallin... Read More about Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function.

Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function (2024)
Journal Article
Chang, C., Banerjee, S. L., Park, S. S., Zhang, X. L., Cotnoir-White, D., Opperman, K. J., …Kania, A. (2024). Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function. eLife, 12, Article RP89176. https://doi.org/10.7554/elife.89176

Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes during development and throughout adulthood. This versatility is likely facilitated by the ability of Eph receptors to signal through diverse cellular signallin... Read More about Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Nayeem Hasan, M., Khalil, I., Baker Chowdhury, M. A., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. GreSIS - Greater South Information System, https://doi.org/10.60692/x6t6v-mbt18

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000-2010 vs. 2011-2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Hasan, M. N., Khalil, I., Chowdhury, M. A. B., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. Journal of Medical Entomology, Article tjae001. https://doi.org/10.1093/jme/tjae001

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000–2010 vs. 2011–2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.

Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics (2024)
Journal Article
Nayeem Hasan, M., Khalil, I., Baker Chowdhury, M. A., Rahman, M., Asaduzzaman, M., Billah, M., …Haider, N. (in press). Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics. GreSIS - Greater South Information System, https://doi.org/10.60692/gc5zx-3tc77

The objectives of this study were to compare dengue virus (DENV) cases, deaths, case-fatality ratio [CFR], and meteorological parameters between the first and the recent decades of this century (2000-2010 vs. 2011-2022) and to describe the trends, se... Read More about Two decades of endemic dengue in Bangladesh (2000–2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.

How ‘hidden hearing loss’ noise exposure affects neural coding in the inferior colliculus of rats (2024)
Journal Article
Bakay, W. M., Cervantes, B., Lao-Rodríguez, A. B., Johannesen, P. T., Lopez-Poveda, E. A., Furness, D. N., & Malmierca, M. S. (2024). How ‘hidden hearing loss’ noise exposure affects neural coding in the inferior colliculus of rats. Hearing Research, 443, Article 108963. https://doi.org/10.1016/j.heares.2024.108963

Exposure to brief, intense sound can produce profound changes in the auditory system, from the internal structure of inner hair cells to reduced synaptic connections between the auditory nerves and the inner hair cells. Moreover, no... Read More about How ‘hidden hearing loss’ noise exposure affects neural coding in the inferior colliculus of rats.

Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells (2024)
Journal Article
Gilbert, H. T. J., Wignall, F. E. J., Zeef, L., Hoyland, J. A., & Richardson, S. M. (2024). Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells. JOR Spine, 7(1), Article 1315. https://doi.org/10.1002/jsp2.1315

Macular pigment profile characteristics and stability over periods of up to 25 years (2024)
Journal Article
Robson, A. G., Van Kuijk, F., Pauleikhoff, D., & Moreland, J. (2024). Macular pigment profile characteristics and stability over periods of up to 25 years. Acta ophthalmologica, 102(S279), https://doi.org/10.1111/aos.16432

This study compares the foveal and total retinal macular pigment (MP) amount in healthy subjects and examines the stability of MP spatial distribution profiles, measured almost annually for periods of up to 25 years.Measurements of MP spatial distrib... Read More about Macular pigment profile characteristics and stability over periods of up to 25 years.

Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes (2024)
Journal Article
Hegde, S., Brettell, L. E., Quek, S., Etebari, K., Saldaña, M. A., Asgari, S., …Hughes, G. L. (2024). Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes. Environmental Microbiology, 26(2), Article e16576. https://doi.org/10.1111/1462-2920.16576

The mosquito microbiome is critical for host development and plays a major role in many aspects of mosquito biology. While the microbiome is commonly dominated by a small number of genera, there is considerable variation in composition among mosquito... Read More about Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field‐caught or laboratory‐reared mosquitoes.