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Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome (2020)
Journal Article
Rashid, & Mamas. (2020). Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome. International Journal of Cardiology, https://doi.org/10.1016/j.ijcard.2020.12.063

Background Risk factors for further bleeding and ischemic events after acute coronary syndrome (ACS) often overlap. Little is known about sex-based differences in the management and outcomes of ACS patients according to their combined bleeding-ische... Read More about Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome.

Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. (2020)
Journal Article
Mamas. (2020). Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. European Journal of Epidemiology, https://doi.org/10.1007/s10654-020-00710-8

The role of dietary calcium in cardiovascular disease prevention is unclear. We aimed to determine the association between calcium intake and incident cardiovascular disease and mortality. Data were extracted from the European Prospective Investigati... Read More about Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis..

The British Association of Dermatologists Biologics and Immunomodulators Register: a centenary celebration of research collaboration in British dermatology (2020)
Journal Article
Yiu, Z., Mason, K., Smith, C., Griffiths, C., & Study Group, B. (2020). The British Association of Dermatologists Biologics and Immunomodulators Register: a centenary celebration of research collaboration in British dermatology. British Journal of Dermatology, 183(6), 981-983. https://doi.org/10.1111/bjd.19536

The coronavirus disease 2019 (COVID‐19) pandemic has led to unexpected challenges and adversity in the centenary year of the British Association of Dermatologists (BAD). However, through challenge comes opportunity. Two national organizations were bo... Read More about The British Association of Dermatologists Biologics and Immunomodulators Register: a centenary celebration of research collaboration in British dermatology.

Indicators of dementia disease progression in primary care: an electronic health record cohort study (2020)
Journal Article
Rathod-Mistry, T., Marshall, M., Campbell, P., Bailey, J., Chew-Graham, C. A., Croft, P., …Jordan, K. P. (2021). Indicators of dementia disease progression in primary care: an electronic health record cohort study. European Journal of Neurology, 28(5), 1499-1510. https://doi.org/10.1111/ene.14710

BACKGROUND: The objectives were to assess the feasibility and validity of using markers of dementia-related health as indicators of dementia progression in primary care, by assessing the frequency they are recorded and by testing the hypothesis they... Read More about Indicators of dementia disease progression in primary care: an electronic health record cohort study.

Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units (2020)
Journal Article
Cheshire, J., Lissauer, D., Parry-Smith, W., Tobias, A., Smith, G. B., Isaacs, R., & Hundley, V. (in press). Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units. Resuscitation Plus, 5, Article 100060. https://doi.org/10.1016/j.resplu.2020.100060

Background The use of obstetric early warning systems (OEWS) are recommended as an adjunct to reduce maternal morbidity and mortality. The aim of this review was to document the variation in OEWS trigger thresholds and the quality of information inc... Read More about Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units.

Exploring women's experiences of identifying, negotiating and managing perinatal anxiety: a qualitative study (2020)
Journal Article
Oh, S., Chew-Graham, C., Silverwood, V., Aksa Shaheen, S., Walsh-House, J., Sumathipala, A., & Kingstone, T. (2020). Exploring women's experiences of identifying, negotiating and managing perinatal anxiety: a qualitative study. BMJ Open, 10(12), Article e040731. https://doi.org/10.1136/bmjopen-2020-040731

OBJECTIVES: Anxiety affects around 15% of women during the perinatal period and can adversely impact both mother and child, with potential implications for long-term health; few studies have examined women's experiences of perinatal anxiety (PNA). In... Read More about Exploring women's experiences of identifying, negotiating and managing perinatal anxiety: a qualitative study.

Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. (2020)
Journal Article
Roddy, & Mamas. (2020). Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. American Journal of Cardiovascular Drugs, https://doi.org/10.1007/s40256-020-00459-1

Hyperuricemia and gout have been linked to an increased risk for cardiovascular (CV) disease, stroke, hypertension, heart failure, and chronic kidney disease, possibly through a proinflammatory milieu. However, not all the drugs used in gout treatmen... Read More about Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes..

Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial (2020)
Journal Article
(2020). Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial. Clinical Rehabilitation, 269215520984025 - ?

OBJECTIVE: To investigate acceptability, barriers to adherence with the interventions, and which outcome measures best reflect the participants' rehabilitation goals in a pilot and feasibility randomised controlled trial evaluating early patient-dire... Read More about Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial.

Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. (2020)
Journal Article
Mycroft-West, C. J., Su, D., Pagani  , I., Rudd  , T. R., Elli  , S., Gandhi  , N. S., …Skidmore   , M. A. (2020). Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. Thrombosis and Haemostasis, 120(12), 1700 - 1715. https://doi.org/10.1055/s-0040-1721319

The dependence of development and homeostasis in animals on the interaction of hundreds of extracellular regulatory proteins with the peri- and extracellular glycosaminoglycan heparan sulfate (HS) is exploited by many microbial pathogens as a means o... Read More about Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin..

Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. (2020)
Journal Article
Mamas. (2020). Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. Heart, 113-119. https://doi.org/10.1101/2020.07.14.20153734

Objective. To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic. Methods. Retrospective cohort of adult (age =18 years) acute cardiovascular deaths (n=587,225) in England and Wales, 1st January 2014 to 30th Jun... Read More about Place and causes of acute cardiovascular mortality during the COVID-19 pandemic..

How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. (2020)
Journal Article
Allen, K., Damery, S. L., Sein, K., Johnson, D. W., Davies, S. J., Lambie, M., …Combes, G. M. (2020). How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 42(3), https://doi.org/10.1177/0896860820975596

BACKGROUND: While numerous studies have explored the patient experience of dialysis or other end-stage kidney disease (ESKD) treatments, few have explored the process of transitioning between dialysis modalities. This study aimed to develop an in-dep... Read More about How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia..

Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care. (2020)
Journal Article
(2020). Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care. Primary Health Care Research and Development, -. https://doi.org/10.1017/S146342362000064X%5BOpens+in+a+new+window%5D

AIM: To explore the experiences of patients living with diabetic lower extremity amputation (DLEA) and its post-amputation wound in primary care. BACKGROUND: DLEA, including both minor and major amputation, is a life-altering condition that brings nu... Read More about Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care..

Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. (2020)
Journal Article
Twohig, H., Owen, C., Muller, S., Mallen, C., Mitchell, C., Hider, S., …Hill, C. (2021). Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. Journal of Rheumatology, 48(6), 883-893. https://doi.org/10.3899/jrheum.200248

OBJECTIVE: To systematically identify the outcome measures and instruments used in clinical studies of polymyalgia rheumatica (PMR) and to evaluate evidence about their measurement properties. METHODS: Searches based on the MeSH term 'polymyalgia rhe... Read More about Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review..

Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. (2020)
Journal Article
Mallen. (2020). Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care. Health Policy and Planning, 341-356. https://doi.org/10.1093/heapol/czaa152

Clinical records in primary healthcare settings in low- and middle-income countries (LMIC) are often lacking or of too poor quality to accurately assess what happens during the patient consultation. We examined the most common methods for assessing h... Read More about Comparing the use of direct observation, standardized patients and exit interviews in low- and middle-income countries: a systematic review of methods of assessing quality of primary care..

Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR) (2020)
Journal Article
Littlewood, C., Bateman, M., Butler-Walley, S., Bathers, S., Bromley, K., Lewis, M., …Foster, N. E. (2020). Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR). Clinical Rehabilitation, 35(6), 829-839. https://doi.org/10.1177/0269215520978859

OBJECTIVE: To evaluate the feasibility of a multi-centre randomised controlled trial to compare the clinical and cost-effectiveness of early patient-directed rehabilitation versus standard rehabilitation following surgical repair of the rotator cuff... Read More about Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR).

Radiation protection in the cardiac catheterisation lab: best practice (2020)
Journal Article
Roguin, A., & Nolan, J. (2021). Radiation protection in the cardiac catheterisation lab: best practice. Heart, 107(1), 76-82. https://doi.org/10.1136/heartjnl-2019-316369

Occupational doses of radiation in cardiac procedures guided by fluoroscopy are the highest registered among medical staff using X-rays.1–5 Electrophysiologists and interventional cardiologists are the group with the highest exposure. Patient and ope... Read More about Radiation protection in the cardiac catheterisation lab: best practice.

'As easy as riding a bike': a systematic review of injuries and illness in road cycling. (2020)
Journal Article
Rooney, D., Sarriegui, I., & Heron, N. (2020). 'As easy as riding a bike': a systematic review of injuries and illness in road cycling. BMJ Open Sport & Exercise Medicine, e000840 - ?. https://doi.org/10.1136/bmjsem-2020-000840

Objectives: To allow the implementation of effective injury and illness prevention programmes for road cyclists, we wanted to first identify the injury/illness burden to this group of athletes. We, therefore, undertook a systematic review of all repo... Read More about 'As easy as riding a bike': a systematic review of injuries and illness in road cycling..