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Association between meniscal volume and development of knee osteoarthritis. (2021)
Journal Article
(2021). Association between meniscal volume and development of knee osteoarthritis. Rheumatology, 1392 - 1399. https://doi.org/10.1093/rheumatology/keaa522

OBJECTIVE: To assess the association between meniscal volume, its change over time and the development of knee OA after 30?months in overweight/obese women. METHODS: Data from the PRevention of knee Osteoarthritis in Overweight Females study were use... Read More about Association between meniscal volume and development of knee osteoarthritis..

Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. (2021)
Journal Article
Mamas. (2021). Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. https://doi.org/10.1007/s11886-021-01453-y

PURPOSE OF REVIEW: This article reviews the evidence on optimal medical therapy (OMT) versus coronary revascularization in patients with stable ischemic heart disease (SIHD) and advanced chronic kidney disease (CKD). RECENT FINDINGS: A post hoc analy... Read More about Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease..

Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease (2021)
Journal Article
Paul, T. K., Mamas, M. A., Shanmugasundaram, M., Nagarajarao, H. S., Ojha, C. P., Jneid, H., …White, C. J. (2021). Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease. Current Cardiology Reports, 23(4), https://doi.org/10.1007/s11886-021-01453-y

Purpose of Review This article reviews the evidence on optimal medical therapy (OMT) versus coronary revascularization in patients with stable ischemic heart disease (SIHD) and advanced chronic kidney disease (CKD). Recent Findings A post hoc an... Read More about Medical Therapy Versus Revascularization in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease.

Are psychological symptoms a risk factor for musculoskeletal pain in adolescents? (2021)
Journal Article
Andreucci, A., Campbell, P., & Dunn, K. (2021). Are psychological symptoms a risk factor for musculoskeletal pain in adolescents?. European Journal of Pediatrics, https://doi.org/10.1007/s00431-021-04002-5

AbstractAdolescent musculoskeletal pain is common and is associated with musculoskeletal pain in adulthood. Psychological symptoms, also common in adolescence, have been shown to be associated with musculoskeletal pain, but the current evidence is mi... Read More about Are psychological symptoms a risk factor for musculoskeletal pain in adolescents?.

Measuring the Effect of Examiner Variability in a Multiple-Circuit Objective Structured Clinical Examination (OSCE) (2021)
Journal Article
Yeates, P., Moult, A., Cope, N., McCray, G., Xilas, E., Lovelock, T., …McKinley, R. K. (. (2021). Measuring the Effect of Examiner Variability in a Multiple-Circuit Objective Structured Clinical Examination (OSCE). Academic Medicine, 96(8), 1189-1196. https://doi.org/10.1097/acm.0000000000004028

Purpose Ensuring that examiners in different parallel circuits of objective structured clinical examinations (OSCEs) judge to the same standard is critical to the chain of validity. Recent work suggests examiner-cohort (i.e., the particular group of... Read More about Measuring the Effect of Examiner Variability in a Multiple-Circuit Objective Structured Clinical Examination (OSCE).

Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting. (2021)
Journal Article
Mallen. (2021). Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting. Rheumatology, 4327-4339. https://doi.org/10.1093/rheumatology/keab067

OBJECTIVE: To determine the burden of comorbidities in osteoarthritis (OA) and their temporal relationships in the UK. METHODS: The Clinical Practice Research Datalink (CPRD) GOLD was used to identify people with incident OA and age, gender and pract... Read More about Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting..

Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database. (2021)
Journal Article
(2021). Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database. Mechanisms of Ageing and Development, https://doi.org/10.1016/j.mad.2021.111436

The prevalence of multimorbidity and polypharmacy increases significantly with age and are associated with negative health consequences. However, most current interventions to optimize medication have failed to show significant effects on patient-rel... Read More about Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database..

Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability (2021)
Journal Article
Faux-Nightingale, A., De Quincey, E., Philp, F., Woolley, S., Pandyan, A., & de Quincey, E. (in press). Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability. BMC Medical Informatics and Decision Making, 21(1), Article ARTN 78. https://doi.org/10.1186/s12911-021-01446-5

Abstract Background Currently the diagnosis of shoulder instability, particularly in children, is difficult and can take time. These diagnostic delays can lead to poorer outcome and long-term complications. A Diagnostic Decision Support System (DDSS)... Read More about Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability.

Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth (2021)
Journal Article
Kwong. (2021). Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth. Cancers,

Thymic stromal lymphopoietin (TSLP) is an epithelial cell derived cytokine belonging to the IL-7 family and a key initiator of allergic inflammation. Two main isoforms of TSLP, classified as long- (lfTSLP) and short-form (sfTSLP), have been reported... Read More about Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth.

Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases (2021)
Journal Article
Dakroub, A., Nasser, S. A., Kobeissy, F., Yassine, H. M., Orekhov, A., Sharifi‐Rad, J., …Eid, A. H. (2021). Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases. Journal of Cellular Physiology, 236(9), 6282-6296. https://doi.org/10.1002/jcp.30345

Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been implicated in vascular remodeling, vascular inflammation, and atherosclerosis... Read More about Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases.

Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample (2021)
Journal Article
Ullah, W., Al-Khadra, Y., Mir, T., Darmoch, F., Pacha, H. M., Sattar, Y., …Alraies, M. C. (2021). Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample. Journal of Cardiovascular Medicine, 22(7), 586 - 593. https://doi.org/10.2459/JCM.0000000000001172

AIM: We sought to determine the racial and ethnical disparities in the delivery of TAVR and to evaluate the in-hospital outcomes and utilization of TAVR stratified by patient ethnicity. METHOD: Using a national inpatient sample database between 2011... Read More about Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample.

Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives (2021)
Journal Article
Nash, A., Kingstone, T., Farooq, S., Tunmore, J., & Chew-Graham, C. A. (2021). Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives. BMJ Open, e042497 - ?. https://doi.org/10.1136/bmjopen-2020-042497

OBJECTIVES: The side effects of antipsychotic medications (APs) can increase the risk of developing physical health conditions. Some APs pose a higher risk than others. Evidence suggests switching to lower risk APs can support physical health outcome... Read More about Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives.

Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions (2021)
Journal Article
Western, L. F., Dhawan, R., Cribb, G., Shepherd, K., & Cool, P. (2021). Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions. Cureus, 13(2), Article e13565. https://doi.org/10.7759/cureus.13565

Background Bone tumours of the talus are a rare cause of ankle pain. This study aims to provide additional clinical clarity regarding the presentation and management of a minimally researched topic. Methods Sixteen patients were diagnosed with b... Read More about Bone Tumours of the Talus: 18-Year Cohort of Patients With Rare Osteoid Lesions.

Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis (2021)
Journal Article
Karia, A. M., Duff, C. J., Heald, A. H., Britton, I., Fryer, A. A., & Wu, P. (2021). Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis. Cardiovascular Endocrinology & Metabolism, 10(2), 120-124. https://doi.org/10.1097/xce.0000000000000245

Objective Accurate diagnosis of polycystic ovarian syndrome (PCOS) enables clinical interventions/cardiometabolic risk factor management. Diagnosis can take over 2 years and multiple clinician contacts. We examined patterns of PCOS-associated biochem... Read More about Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis.

Cross-cultural validation of the start back screening tool in a Greek low back pain sample. (2021)
Journal Article
Billis, E., Fousekis, K., Tsekoura, M., Lampropoulou, S., Matzaroglou, C., Gliatis, J., …Strimpakos, N. (2021). Cross-cultural validation of the start back screening tool in a Greek low back pain sample. Musculoskeletal Science and Practice, 53, 1-6. https://doi.org/10.1016/j.msksp.2021.102352

BACKGROUND: Keele STarT Back Screening Tool (SBST) is a popular 9-item prognostic recovery questionnaire for low back pain (LBP) with validation studies in several cultural settings, but not Greek. OBJECTIVES: The cross-cultural adaptation and valida... Read More about Cross-cultural validation of the start back screening tool in a Greek low back pain sample..

Judo Injuries Frequency in Europe's Top-Level Competitions in the Period 2005-2020. (2021)
Journal Article
(2021). Judo Injuries Frequency in Europe's Top-Level Competitions in the Period 2005-2020. Journal of Clinical Medicine, https://doi.org/10.3390/jcm10040852

BACKGROUND: The present study assesses the frequency of injury in Europe's top-level judokas, during top-level competitions, and defines risk factors. METHODS: The members of the EJU Medical Commission collected injury data over the period of 2005 to... Read More about Judo Injuries Frequency in Europe's Top-Level Competitions in the Period 2005-2020..