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Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals (2025)
Journal Article
Chaplin, H., Simpson, C., Wilkins, K., Meehan, J., Ng, N., Galloway, J., Scott, I. C., Sen, D., Tattersall, R., Moss‐Morris, R., Lempp, H., & Norton, S. (2025). Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals. British Journal of Health Psychology, 30(1), Article e12780. https://doi.org/10.1111/bjhp.12780

Objectives: This study aims to explore patients' and clinicians' understanding and experiences of refractory disease (RD) and persistent physical and emotional symptoms (PPES) in patients with inflammatory arthritis (IA), namely rheumatoid arthritis... Read More about Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals.

Pharmaco-Invasive Strategy Vs Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction in Latin America: A Meta-Analysis (2025)
Journal Article
Diaz-Arocutipa, C., Vargas-Rivas, C., Mendoza-Quispe, D., Benites-Moya, C. J., Torres-Valencia, J., Valenzuela-Rodriguez, G., Gamarra-Valverde, N. N., Chacon-Diaz, M., Costabel, J. P., Mamas, M. A., & Vicent, L. (in press). Pharmaco-Invasive Strategy Vs Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction in Latin America: A Meta-Analysis. CJC Open, 7(1), 78-87. https://doi.org/10.1016/j.cjco.2024.10.005

Background
Primary percutaneous coronary intervention (PCI) is the established treatment for ST-segment elevation myocardial infarction (STEMI), but often it is not readily available in low-resource settings. We a... Read More about Pharmaco-Invasive Strategy Vs Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction in Latin America: A Meta-Analysis.

The 2023 fatal dengue outbreak in Bangladesh highlights a paradigm shift of geographical distribution of cases (2025)
Journal Article
Hasan, M. N., Rahman, M., Uddin, M., Ashrafi, S. A. A., Rahman, K. M., Paul, K. K., Sarker, M. F. R., Haque, F., Sharma, A., Papakonstantinou, D., Paudyal, P., Asaduzzaman, M., Zumla, A., & Haider, N. (2025). The 2023 fatal dengue outbreak in Bangladesh highlights a paradigm shift of geographical distribution of cases. Epidemiology and Infection, 153, https://doi.org/10.1017/S0950268824001791

In 2023, Bangladesh experienced its largest and deadliest outbreak of the Dengue virus (DENV), reporting the highest-ever recorded annual cases and deaths. Historically, most of the cases were recorded in the capital city, Dhaka. We aimed to characte... Read More about The 2023 fatal dengue outbreak in Bangladesh highlights a paradigm shift of geographical distribution of cases.

Sexual Health, Pleasure, Justice, and Well‐Being in People With Rheumatic and Musculoskeletal Diseases: A Scoping Review Protocol (2025)
Journal Article
Giardulli, B., Prior, Y., Bumin, G., Kinikli, G. I., Stones, S. R., Prior, J. A., Flurey, C., Testa, M., Lavender, A., & Battista, S. (2025). Sexual Health, Pleasure, Justice, and Well‐Being in People With Rheumatic and Musculoskeletal Diseases: A Scoping Review Protocol. Musculoskeletal Care, 23(1), Article e70040. https://doi.org/10.1002/msc.70040

Introduction: Sexual health, pleasure, justice (equity in sexual rights and experiences), and well‐being are crucial determinants of health and life quality, yet often overlooked in the rheumatic and musculoskeletal diseases (RMD) field. However, thi... Read More about Sexual Health, Pleasure, Justice, and Well‐Being in People With Rheumatic and Musculoskeletal Diseases: A Scoping Review Protocol.

AB0149 Is chemokine receptor CCR9 required for leukocyte recruitment in inflammation in rheumatoid arthritis? deficiency of CCR9 in a murine model of antigen-induced arthritis (2025)
Journal Article
Cartwright, A., Middleton, J., Askari, A., & Kehoe, O. (in press). AB0149 Is chemokine receptor CCR9 required for leukocyte recruitment in inflammation in rheumatoid arthritis? deficiency of CCR9 in a murine model of antigen-induced arthritis. Annals of the Rheumatic Diseases, 71(3), 646. https://doi.org/10.1136/annrheumdis-2012-eular.149

Background
Rheumatoid arthritis (RA) is characterized by accumulation of leukocytes in the synovial membrane and fluid of affected joints. Chemokine receptors on leukocytes mediate recruitment of these cells and i... Read More about AB0149 Is chemokine receptor CCR9 required for leukocyte recruitment in inflammation in rheumatoid arthritis? deficiency of CCR9 in a murine model of antigen-induced arthritis.

POS1458-HPR TRENDS OF PREVALENCE AND INCIDENCE OF CHRONIC SHOULDER PAIN IN THE UNITED KINGDOM: FINDINGS FROM THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) (2025)
Journal Article
Alotaibi, N., Swain, S., Vinogradova, Y., Iyen, B., Doherty, M., Zhang, W., & Hall, M. (in press). POS1458-HPR TRENDS OF PREVALENCE AND INCIDENCE OF CHRONIC SHOULDER PAIN IN THE UNITED KINGDOM: FINDINGS FROM THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD). Annals of the Rheumatic Diseases, 83, 1186. https://doi.org/10.1136/annrheumdis-2024-eular.1411

Background:
Chronic shoulder pain (CSP) is a common musculoskeletal condition that can lead to sleeping difficulties, work disability and functional limitations in daily activities [1,2]. There is a gap in the evi... Read More about POS1458-HPR TRENDS OF PREVALENCE AND INCIDENCE OF CHRONIC SHOULDER PAIN IN THE UNITED KINGDOM: FINDINGS FROM THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD).

Long-range directional growth of neurites induced by magnetic forces (2025)
Journal Article
Nahar, T., Gates, M., Secret, E., Siaugue, J.-M., Fresnais, J., Rotherham, M., Fuller, H. R., Brown, S. J., El Haj, A. J., & Telling, N. D. (2025). Long-range directional growth of neurites induced by magnetic forces. Acta biomaterialia, https://doi.org/10.1016/j.actbio.2024.12.057

The ability to control the growth and orientation of neurites over long distances has significant implications for regenerative therapies and the development of physiologically relevant brain tissue models. In this study, the forces generated on magn... Read More about Long-range directional growth of neurites induced by magnetic forces.

How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England (2024)
Journal Article
Allen, K., Shaw, K. L., Spry, J. L., Dikomitis, L., Coyle, D., Damery, S., Fotheringham, J., Lambie, M., Williams, I. P., & Davies, S. (2024). How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England. BMJ Open, 14(12), https://doi.org/10.1136/bmjopen-2024-085754

Objective: The proportion of people having home dialysis for kidney disease varies considerably by treating centre, socioeconomic deprivation levels in the area and to some extent ethnicity. This study aimed to gain in-depth insights into cultural an... Read More about How does organisational culture facilitate uptake of home dialysis? An ethnographic study of kidney centres in England.

Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs (2024)
Journal Article
Slob, E. M. A., Vijverberg, S. J. H., Ruffles, T., Noij, L. C. E., Biermann, J., Brouwer, A. F. J., van den Brink, K., de Bruin‐Kok, A., Van Ewijk, B. E., Haarman, E., Hammer, S. C., Hashimoto, S., Hogarth, F., Jones, C. J., Kamps, A. W. A., Kersten, E. T. G., de Kleer, I., Lipworth, B. J., Littleford, R., Mérelle, M., …Maitland‐van der Zee, A. H. (in press). Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs. Allergy, https://doi.org/10.1111/all.16438

Background: Long‐acting beta2‐agonists (LABA) in combination with inhaled corticosteroids (ICS) are commonly used to treat asthma, however, some children lack response to the addition of LABA. This might be partially due to the presence of the Arg16G... Read More about Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two RCTs.

Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. (2024)
Journal Article
Chew, N. W. S., Mehta, A., Goh, R. S. J., Zhang, A., Chen, Y., Chong, B., Chew, H. S. J., Shabbir, A., Brown, A., Dimitriadis, G. K., Huang, D. Q., Foo, R., le Roux, C. W., Figtree, G. A., Fudim, M., Pandey, A., Mamas, M. A., Hausenloy, D. J., Richards, A. M., Nicholls, S. J., …Sperling, L. S. (2025). Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. Circulation, 151(1), 98-119. https://doi.org/10.1161/CIRCULATIONAHA.124.070535

There is a new awareness of the widespread nature of metabolic dysfunction-associated steatotic liver disease (MASLD) and its connection to cardiovascular disease (CVD). This has catalyzed collaboration between cardiologists, hepatologists, endocrino... Read More about Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach..

How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. (2024)
Journal Article
Murphy, A. C., Carroll, W., Gotsell, M., Potter, C., Quint, J. K., & Malone, R. (in press). How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. BMJ Open Respiratory Research, 11(1), e002579. https://doi.org/10.1136/bmjresp-2024-002579

Inhalers are widely used for the management of asthma and chronic obstructive pulmonary disease. However, there is little knowledge about the extent to which an inhaler is used and when it is disposed of, despite the implications for an individual's... Read More about How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey..

Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review] (2024)
Journal Article
Raquel Nunes, A., Atherton, H., Dahlmann, F., Eccles, A., Geddes, O., Gregg, M., Jowett, S., Karaba, F., Nelson, L., Spencer, R., Twohig, H., & Dale, J. (2024). Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review]. NIHR Open Research, 1-11. https://doi.org/10.3310/nihropenres.13833.1

Introduction
The urgency to address climate change and reduce carbon emissions in healthcare, highlighted in the United Kingdom (UK) by the 'Delivering a 'Net Zero' National Health Service (NHS)' report, emphasises the need for healthcare organisati... Read More about Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review].

Cardiovascular diseases in patients with cancer: A comprehensive review of epidemiological trends, cardiac complications, and prognostic implications (2024)
Journal Article
Alshahrani, A. A., Kontopantelis, E., Morgan, C., Ravindrarajah, R., Martin, G. P., & Mamas, M. A. (in press). Cardiovascular diseases in patients with cancer: A comprehensive review of epidemiological trends, cardiac complications, and prognostic implications. Chinese Medical Journal, https://doi.org/10.1097/cm9.0000000000003419

This article provides an overview of the current evidence on the epidemiology, overlapping risk factors, and pathophysiology of cardiovascular disease (CVD) in patients with cancer. It explores the cardiotoxic effects of anticancer therapy and their... Read More about Cardiovascular diseases in patients with cancer: A comprehensive review of epidemiological trends, cardiac complications, and prognostic implications.

Evaluating the use of electromyography in UK and European gait laboratories for the assessment of cerebral palsy and other neurological and musculoskeletal conditions (2024)
Journal Article
Shepherd, H., Reeves, J., & Stewart, C. (in press). Evaluating the use of electromyography in UK and European gait laboratories for the assessment of cerebral palsy and other neurological and musculoskeletal conditions. Gait & Posture, 117, 143-152. https://doi.org/10.1016/j.gaitpost.2024.12.018


Background
Electromyography (EMG) can estimate the magnitude and timing of muscle activation during walking in those with gait disorders. Despite the potential of EMG use in assessment and clinical decision-making... Read More about Evaluating the use of electromyography in UK and European gait laboratories for the assessment of cerebral palsy and other neurological and musculoskeletal conditions.

Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. (2024)
Journal Article
Cole, A., Weight, N., Misra, S., Grapsa, J., Rutter, M. K., Siudak, Z., Moledina, S., Kontopantelis, E., Khunti, K., & Mamas, M. A. (in press). Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. Diabetologia, https://doi.org/10.1007/s00125-024-06337-8

The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population. (2024)
Journal Article
Stedman, M., Heald, A. H., Holland, D., Halsall, I., Green, L., Wu, P., Patel, K., Scargill, J., Gibson, M., Hanna, F. W. F., & Fryer, A. A. (in press). The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population. Diabetes Therapy, https://doi.org/10.1007/s13300-024-01680-w

We previously reported sex differences in the distribution of glycated haemoglobin (HbA1c) for men/women aged < 50 years vs older individuals, with implications for delayed diabetes diagnosis. Here, we explored whether this pattern was also seen in m...

Psoriatic Arthritis Priority Setting Partnership: patient- and clinician-informed considerations for future UK health service delivery. (2024)
Journal Article
James, L., Hailey, L., Bundy, C., Burstow, H., Chandler, D., Cowper, R., Helliwell, P., Joannes, L., Kelly, A., Kennedy, B., Kinsella, S., McAteer, H., Mukherjee, S., Packham, J., Wise, E., Young, H., Dures, E., & Coates, L. C. (in press). Psoriatic Arthritis Priority Setting Partnership: patient- and clinician-informed considerations for future UK health service delivery. Rheumatology, 1-6. https://doi.org/10.1093/rheumatology/keae680

Little is known about the ideal service delivery model and shortcomings in patient experiences in the NHS for patients with Psoriatic Arthritis (PsA). To identify unmet needs perceived within the current health service delivery model for PsA from the... Read More about Psoriatic Arthritis Priority Setting Partnership: patient- and clinician-informed considerations for future UK health service delivery..

A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides (2024)
Journal Article
Shen, Z., Simard, M., Brand, D., Andrei, V., Al-Khader, A., Oumlil, F., Trevers, K., Butters, T., Haefliger, S., Kara, E., Amary, F., Tirabosco, R., Cool, P., Royle, G., Hawkins, M. A., Flanagan, A. M., & Collins-Fekete, C.-A. (in press). A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides. Communications Biology, 7(1), 1674. https://doi.org/10.1038/s42003-024-07398-6

Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incor... Read More about A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

How Does Thyroid Hormone Profile Differ on and Off Replacement Treatment? (2024)
Journal Article
Heald, A. H., Premawardhana, L. D., Taylor, P. N., Baker, A., Chaudhury, N., Fryer, A. A., Okosieme, O. E., Dayan, C. M., & Stedman, M. (in press). How Does Thyroid Hormone Profile Differ on and Off Replacement Treatment?. Clinical Endocrinology, 1-6. https://doi.org/10.1111/cen.15185

Introduction: There continues to be much discussion around optimisation of thyroid hormone status in hypothyroid individuals. We here looked the way that free T4(FT4) and thyroid‐stimulating hormone (TSH) related to each other in a large laboratory s... Read More about How Does Thyroid Hormone Profile Differ on and Off Replacement Treatment?.