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Burden of smoking-related stroke in Saudi Arabia: trends from 1990 to 2021 (2025)
Journal Article
Alqahtani, J. S., AlDraiwiesh, I. A., Aldhahir, A. M., & Oyelade, T. (2025). Burden of smoking-related stroke in Saudi Arabia: trends from 1990 to 2021. PloS one, 20(5), Article e0324039. https://doi.org/10.1371/journal.pone.0324039

Background: Stroke ranks among the top causes of death and disability globally, with smoking being a significant risk factor for its development. This study aims to assess the impact of smoking-related strokes in Saudi Arabia from 1990 to 2021. Metho... Read More about Burden of smoking-related stroke in Saudi Arabia: trends from 1990 to 2021.

Geographical Association of Bird Species Richness with All-Cause and Cause-Specific Mortality Rates of Local Residents: An Ecological Study in China (2025)
Journal Article
Zhang, N., You, J., Xu, Q., Cai, J., Jordan, K. P., Li, L., Yu, T., & Chen, Y. (2025). Geographical Association of Bird Species Richness with All-Cause and Cause-Specific Mortality Rates of Local Residents: An Ecological Study in China. Life, 15(6), Article 875. https://doi.org/10.3390/life15060875

The pressing ecological challenges of the twenty-first century underscore the need for biodiversity protection. The “One Health” approach, which integrates human, animal, and environmental health, has become increasingly vital. This study investigate... Read More about Geographical Association of Bird Species Richness with All-Cause and Cause-Specific Mortality Rates of Local Residents: An Ecological Study in China.

Waking Salivary Cortisone vs Serum Cortisol in the Short Synacthen Test in Screening for Adrenocortical Insufficiency: Results of a Service Evaluation (2025)
Journal Article
Heald, A., Mordaunt, M., Gallant, N., Baker, H., Majeed, W., Kochhar, R., Syed, A. A., Mudaliar, R., Abushufa, R., Hanna, F., Marshall, D., Laing, I., Keevil, B., & Fryer, A. A. (online). Waking Salivary Cortisone vs Serum Cortisol in the Short Synacthen Test in Screening for Adrenocortical Insufficiency: Results of a Service Evaluation. Clinical Endocrinology, https://doi.org/10.1111/cen.15279

The Cost-Effectiveness of Initiating Patients on Home Dialysis Compared with In-Centre Haemodialysis (2025)
Journal Article
Hill, H., Fotheringham, J., Potts, J., Solis-Trapala, I., Lambie, M., Damery, S., Allen, K., Wailoo, A., Williams, I., & Davies, S. (2025). The Cost-Effectiveness of Initiating Patients on Home Dialysis Compared with In-Centre Haemodialysis. Applied Health Economics and Health Policy, https://doi.org/10.1007/s40258-025-00976-7

Objectives
Kidney failure can be treated at home with peritoneal dialysis or home haemodialysis. The combination of reduced staffing, transport and overhead costs and improved quality of life through treatment at home could make initiating dialysis... Read More about The Cost-Effectiveness of Initiating Patients on Home Dialysis Compared with In-Centre Haemodialysis.

Evidence from other healthcare professions to support the standardisation of clinical assessment in pre-registration education for diagnostic radiography: a systematic review (2025)
Journal Article
Wyke, E., Coleman, G., Holdcroft, D., Tulloch, R., Whitehead, B., & Hyde, E. (in press). Evidence from other healthcare professions to support the standardisation of clinical assessment in pre-registration education for diagnostic radiography: a systematic review. Radiography, 31(4), Article 102986. https://doi.org/10.1016/j.radi.2025.102986

Introduction
This review aimed to gather, assess and synthesise the existing literature pertaining to the standardisation of clinical assessment tools in pre-registration education for competency-based healthcare... Read More about Evidence from other healthcare professions to support the standardisation of clinical assessment in pre-registration education for diagnostic radiography: a systematic review.

Self-management interventions for common long-term conditions in low- and middle-income countries: a synthesis of current evidence. (2025)
Journal Article
Akhal, T., Gabra, M., Adesokan, M., & Babatunde, O. O. (in press). Self-management interventions for common long-term conditions in low- and middle-income countries: a synthesis of current evidence. Journal of Global Health, 15(04148), https://doi.org/10.7189/jogh.15.04148

In addition to endemic communicable diseases, resource-poor health systems in low- and middle-income countries (LMICs) are buckling under an increasing prevalence, morbidity, and mortality attributable to non-communicable diseases (NCD) - 'NCDs crisi... Read More about Self-management interventions for common long-term conditions in low- and middle-income countries: a synthesis of current evidence..

Physiotherapy Capabilities in the Health Care of Adult Patients at Increased Risk of Osteoporotic Fractures: A Scoping Review Protocol (2025)
Journal Article
Blackman, F., Walsh, N., & Paskins, Z. (2025). Physiotherapy Capabilities in the Health Care of Adult Patients at Increased Risk of Osteoporotic Fractures: A Scoping Review Protocol. Musculoskeletal Care, 23(2 - June 2025), Article e70125. https://doi.org/10.1002/msc.70125

Objectives: This scoping review will explore and map the extent and type of literature related to physiotherapy capabilities in the health care of adult patients at increased risk of osteoporotic fractures and identify gaps in the literature. Backgro... Read More about Physiotherapy Capabilities in the Health Care of Adult Patients at Increased Risk of Osteoporotic Fractures: A Scoping Review Protocol.

Secondary healthcare utilization among users of a self-management application for musculoskeletal pain: A prospective cohort study based on 12,842 individuals in Denmark. (2025)
Journal Article
Simonsen, N. S., Nielsen, R. Ø., Budtz, C. R., Christiansen, D. H., Bibby, B. M., Skejø, S. D., Hill, J., & Jacobsen, J. S. (in press). Secondary healthcare utilization among users of a self-management application for musculoskeletal pain: A prospective cohort study based on 12,842 individuals in Denmark. Musculoskeletal Science and Practice, 78(August 2025), Article 103356. https://doi.org/10.1016/j.msksp.2025.103356

To identify which users of a self-management app for musculoskeletal pain are more likely to utilize secondary healthcare (i.e., specialist services within the musculoskeletal domain following primary care referrals). Cohort study with one-year follo... Read More about Secondary healthcare utilization among users of a self-management application for musculoskeletal pain: A prospective cohort study based on 12,842 individuals in Denmark..

Remote digital health interventions to support physical, functional and/or psychological rehabilitation of adult patients with major traumatic injuries: Protocol for a systematic review of randomised controlled trials (Preprint) (2025)
Journal Article
Al-Jabr, H., Salt, E., Stephenson, J., Hamdan, E., & Helliwell, T. (in press). Remote digital health interventions to support physical, functional and/or psychological rehabilitation of adult patients with major traumatic injuries: Protocol for a systematic review of randomised controlled trials (Preprint). JMIR Research Protocols, https://doi.org/10.2196/67675

Background:

Digital health (DH) interventions have increased across the past two decades, providing patients with alternative remote pathways to receiving healthcare services. Patients with major trauma frequently require long-term access to healt... Read More about Remote digital health interventions to support physical, functional and/or psychological rehabilitation of adult patients with major traumatic injuries: Protocol for a systematic review of randomised controlled trials (Preprint).

The impact of intensive management on pain intensity in patients with rheumatoid arthritis and psoriatic arthritis: secondary analysis of three clinical trials. (2025)
Journal Article
Ibrahim, F., Scott, D. L., & Scott, I. C. (2025). The impact of intensive management on pain intensity in patients with rheumatoid arthritis and psoriatic arthritis: secondary analysis of three clinical trials. BMC Rheumatology, 9(1), Article 55. https://doi.org/10.1186/s41927-025-00493-z

Understanding the impact of intensive treatment on pain in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) is crucial to informing the application of evidence-based arthritis pain care. The impact of intensive treatment on infla... Read More about The impact of intensive management on pain intensity in patients with rheumatoid arthritis and psoriatic arthritis: secondary analysis of three clinical trials..

Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline. (2025)
Journal Article
Lamelas, P., Pompeu Sá, M., Izcovich, A., Bottaro, F., Tisi Baña, M., Sosa Liprandi, M. I., Lanas, F., Vilca Mejia, O. A., Zuñiga Luna, M., Aubanel, P., Munera, A., Contreras Reyes, J., Bagur, R., Whitlock, R., Garcia Garcia, H., Mamas, M., Cohen, M. G., Ricalde, A., Abizaid, A., Mendiz, O., …Ragusa, M. A. (2025). Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline. International Journal of Cardiology, 436(1 October 2025), Article 133401. https://doi.org/10.1016/j.ijcard.2025.133401

Severe left main coronary artery disease (LMD) poses a major treatment challenge in Latin America, where both percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are used. This guideline was developed de novo using the... Read More about Percutaneous or surgical revascularization in patients with severe left main coronary artery disease in Latin America: A GRADE clinical practice guideline..

Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper (2025)
Journal Article
Escaned, J., Lombardi, M., Götberg, M., Amabile, N., Banning, A., Barbato, E., Brugaletta, S., Chen, S.-L., Doshi, D., Koo, B.-K., Kozuma, K., Mahadevan, K., Milasinovic, D., Sinning, J.-M., Toth, G., Gonzalo, N., Mamas, M. A., & Kirtane, A. J. (2025). Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper. Journal of the Society for Cardiovascular Angiography & Interventions, 103607. https://doi.org/10.1016/j.jscai.2025.103607

Intracoronary imaging (ICI) was introduced over 3 decades ago to complement conventional coronary angiography, yet its widespread uptake remains limited. This paper seeks to explore the potential causes behind low ICI utilization. The concepts of acc... Read More about Factors Contributing to Low Utilization of Intracoronary Imaging in Clinical Practice: A White Paper.

A mental imagery intervention targeting suicidal ideation in university students: An assessor-blind, randomised controlled feasibility trial. (2025)
Journal Article
Palmier-Claus, J., Duxbury, P., Pratt, D., Parker, S., Sutton, C., Lobban, F., Moorhouse, J., Kerry, E., Russell, C., Nyakutsikwa, B., Drake, R., Eccles, S., Randles, N., Patel, R., Kelly, J., Tattersall, R., & Taylor, P. J. (2025). A mental imagery intervention targeting suicidal ideation in university students: An assessor-blind, randomised controlled feasibility trial. Behaviour Research and Therapy, 191(August 2025), Article 104780. https://doi.org/10.1016/j.brat.2025.104780

The Broad-Minded Affective Coping (BMAC) intervention is a theory-driven cognitive therapy aiming to reduce suicidal ideation through guided positive mental imagery. We explored the feasibility and acceptability of a randomised controlled trial to ev... Read More about A mental imagery intervention targeting suicidal ideation in university students: An assessor-blind, randomised controlled feasibility trial..

Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease. (2025)
Journal Article
Abomoawad, A., Sedhom, R., Golwala, H., Abdelazeem, M., Mamas, M., Jneid, H., Bavry, A. A., Kumbhani, D. J., Kapadia, S., & Elbadawi, A. (2025). Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease. Cardiology and Therapy, https://doi.org/10.1007/s40119-025-00415-7

There is a paucity of data regarding the trends and comparative outcomes of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) among patients with polyvascular disease (PVD). The Nationwide Readmissions Data... Read More about Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease..

Machine Learning-Based Dose Prediction in [177Lu]Lu-PSMA-617 Therapy by Integrating Biomarkers and Radiomic Features from [68Ga]Ga-PSMA-11 Positron Emission Tomography/Computed Tomography (2025)
Journal Article
Yazdani, E., Sadeghi, M., Karamzade-Ziarati, N., Jabari, P., Amini, P., Vosoughi, H., Akbari, M. S., Asadi, M., Kheradpisheh, S. R., & Geramifar, P. (2025). Machine Learning-Based Dose Prediction in [177Lu]Lu-PSMA-617 Therapy by Integrating Biomarkers and Radiomic Features from [68Ga]Ga-PSMA-11 Positron Emission Tomography/Computed Tomography. International Journal of Radiation Oncology - Biology - Physics, https://doi.org/10.1016/j.ijrobp.2025.05.014

The study aimed to develop machine learning (ML) models for pretherapy prediction of absorbed doses (ADs) in kidneys and tumoral lesions for metastatic castration-resistant prostate cancer (mCRPC) patients undergoing [ Lu]Lu-PSMA-617 (Lu-PSMA) radiol... Read More about Machine Learning-Based Dose Prediction in [177Lu]Lu-PSMA-617 Therapy by Integrating Biomarkers and Radiomic Features from [68Ga]Ga-PSMA-11 Positron Emission Tomography/Computed Tomography.

A non-specialist worker delivered digital assessment of cognitive development (DEEP) in young children: a longitudinal validation study in rural India (2025)
Journal Article
Bhavnani, S., Ranjan, A., Mukherjee, D., Divan, G., Prakash, A., Yadav, A., Lal, C., Gajria, D., Irfan, H., Sharma, K. K., Todkar, S. D., Patel, V., & McCray, G. (2025). A non-specialist worker delivered digital assessment of cognitive development (DEEP) in young children: a longitudinal validation study in rural India. PLOS Digital Health, 4(5), Article e0000824. https://doi.org/10.1371/journal.pdig.0000824

Cognitive development in early childhood is critical for life-long well-being. Existing cognitive development surveillance tools require lengthy parental interviews and observations of children. Developmental Assessment on an E-Platform (DEEP) is a d... Read More about A non-specialist worker delivered digital assessment of cognitive development (DEEP) in young children: a longitudinal validation study in rural India.

Predicting mortality risk using the PREVENT equation across diverse racial groups. (2025)
Journal Article
Kobo, O., Rutter, M. K., Misra, S., Michos, E. D., Myint, P. K., Roguin, A., Sun, L. Y., & Mamas, M. A. (2025). Predicting mortality risk using the PREVENT equation across diverse racial groups. American Journal of Managed Care, 31(5), e113-e119. https://doi.org/10.37765/ajmc.2025.89734

The Predicting Risk of CVD Events (PREVENT) score offers a contemporary tool for assessing cardiovascular risk without incorporating race, which has raised concerns about its performance across diverse racial and ethnic groups. We aimed to validate t... Read More about Predicting mortality risk using the PREVENT equation across diverse racial groups..

Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database. (2025)
Journal Article
Castaldi, G., Matetić, A., Bagur, R., Abbott, J. D., Alasnag, M., Chieffo, A., Wijeysundera, H. C., & Mamas, M. A. (2025). Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database. Journal of the American Heart Association, 14(10), Article e038463. https://doi.org/10.1161/JAHA.124.038463

Referral for valve intervention for severe aortic stenosis (AS) may exhibit sex-associated disparities independent of the growth of transcatheter interventions. This study aimed to determine whether there were sex-associated differences in the use of... Read More about Sex-Associated Disparities in Surgical and Percutaneous Management of Aortic Stenosis With Severe Features: Retrospective Analysis From the National Readmission Database..

Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway (2025)
Journal Article
Ebrahim, N., Al Saihati, H. A., Alali, Z., Mahmoud, S. Y. M., Rabaan, A. A., Dessouky, A. A., Salim, R. F., Shamaa, A. A., Abdallah, A. N., Elsherbiny, N. M., Othman, G., Badawy, A. A., Di Leva, G., & Badr, O. A. (2025). Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway. Current Stem Cell Research and Therapy, 16(1), Article 244. https://doi.org/10.1186/s13287-025-04284-8

Background: The JAK/STAT signaling pathway plays a crucial role in the release of interferons (IFNs) and the proinflammatory response during SARS-CoV-2 infection, contributing to the cytokine storm characteristic of severe COVID-19 cases. STAT3, a ke... Read More about Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway.