All Outputs (4695)

A person-centred primary care pharmacist-led osteoporosis review for optimising medicines (PHORM): a protocol for the development and co-design of a model consultation intervention (2024)
Journal Article
Sturrock, A., Grabrovaz, M., Bullock, L., Clark, E., Finch, T., Haining, S., …Paskins, Z. (2024). A person-centred primary care pharmacist-led osteoporosis review for optimising medicines (PHORM): a protocol for the development and co-design of a model consultation intervention. BMJ Open, 14(11), https://doi.org/10.1136/bmjopen-2024-085323

Introduction: Adherence to medicines in osteoporosis is poor, with estimated 1 year persistence rates between 16% and 60%. Poor adherence is complex, relating to combinations of fear of side effects, beliefs about medication being unnecessary, doubts... Read More about A person-centred primary care pharmacist-led osteoporosis review for optimising medicines (PHORM): a protocol for the development and co-design of a model consultation intervention.

Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. (2024)
Journal Article
Istanbuly, S., Matetić, A., Bang, V., Sharma, K., Golwala, H., Kheiri, B., …Mamas, M. A. (2024). Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. Croatian Medical Journal, 65(5), 405-416

To evaluate outcomes after percutaneous coronary intervention (PCI) in patients with cancer and atrial fibrillation (AF). Data of all adult discharges undergoing PCI between October 2015 and December 2018 were obtained from the National Inpatient Sam... Read More about Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study..

Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials (2024)
Journal Article
Elbadawi, A., Hamed, M., Gad, M., Elseidy, S. A., Barghout, M., Jneid, H., …Elgendy, I. Y. (in press). Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials. Journal of the American Heart Association, 13(21), https://doi.org/10.1161/jaha.124.035535

Background The comparative outcomes with immediate, staged in‐hospital, and staged out‐of‐hospital complete revascularization for patients with ST‐segment–elevation myocardial infarction and multivessel disease remain unclear. Methods and Results An... Read More about Immediate Versus Staged Complete Revascularization for Patients With ST‐Segment–Elevation Myocardial Infarction and Multivessel Disease: A Network Meta‐Analysis of Randomized Trials.

A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2 (2024)
Journal Article
Todd, F., Wong, C., Gogola, L., Skyrme-Jones, A., Ghosh, A. K., Garg, P., …Dastidar, A. (2024). A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1190

Background Admission with acute heart failure carries a poor prognosis. Multiple predictive risk scores exist in heart failure presentation, however the utility of these scores in acute heart failure setting among older adults is limited. Aim The pur... Read More about A practical risk score for prediction of 6-month mortality in patients with acute heart failure: CHAM2P2.

In at the Deep End: Innovative approaches to engaging underserved communities in Northern England (2024)
Journal Article
Jeffries, J., Wearn, A., Hassan, S., Fryer, K., Mitchell, C., & Sowden, S. (2024). In at the Deep End: Innovative approaches to engaging underserved communities in Northern England. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.956

Background People living in socio-economically deprived communities have greater health needs, but worse access and outcomes from care. A growing international movement of Deep End (DE) general practice networks established to promote health equity,... Read More about In at the Deep End: Innovative approaches to engaging underserved communities in Northern England.

Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies (2024)
Journal Article
Moriarty, A. S., Paton, L. W., Snell, K. I., Archer, L., Riley, R. D., Buckman, J. E., …McMillan, D. (2024). Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies. BMJ Mental Health, 27(1), https://doi.org/10.1136/bmjment-2024-301226

Background: Relapse of depression is common and contributes to the overall associated morbidity and burden. We lack evidence-based tools to estimate an individual’s risk of relapse after treatment in primary care, which may help us more effectively t... Read More about Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data from multiple studies.

Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD (2024)
Journal Article
Kobo, O., Kaur, G., Gulati, M., & Mamas, M. (2024). Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.3071

Background The American Heart Association’s Life’s Essential 8 (LE8) score is a helpful tool to quantify cardiovascular health (CVH) metrics. Sex differences in relation to LE8 and its association with mortality are not known. Methods The National He... Read More about Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD.

Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study (2024)
Journal Article
Cole, A., Weight, N., Mishra, S., Grapsa, J., Rutter, M., Siudak, Z., …Mamas, M. (2024). Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1533

Background Diabetes mellitus (DM) is an important risk factor for non−ST segment elevation myocardial infarction (NSTEMI). How DM is related to management and longer-term clinical outcomes in contemporary NSTEMI cohorts is not well described. Methods... Read More about Addressing disparities in the long-term mortality of non-ST segment myocardial infarction (NSTEMI) patients according to the presence of diabetes mellitus: a nationwide cohort study.

Hemodynamic and clinical outcomes with balloon-expandable valves versus self-expanding valves in patients with small aortic annulus undergoing transcatheter aortic valve replacement: A meta-analysis of randomized controlled trials and propensity score matched studies (2024)
Journal Article
Ahmed, M., Ahsan, A., Tabassum, S., Tariq, I., Zulfiqar, E., Raja, M. F., …Mamas, M. A. (2024). Hemodynamic and clinical outcomes with balloon-expandable valves versus self-expanding valves in patients with small aortic annulus undergoing transcatheter aortic valve replacement: A meta-analysis of randomized controlled trials and propensity score matched studies. IJC Heart & Vasculature, 55, Article 101542. https://doi.org/10.1016/j.ijcha.2024.101542

Transcatheter aortic valve replacement (TAVR) is considered more effective than surgical aortic valve implantation for patients with a small aortic annulus (SAA), however, the comparative efficacy of different transcatheter heart valves (THVs) remain... Read More about Hemodynamic and clinical outcomes with balloon-expandable valves versus self-expanding valves in patients with small aortic annulus undergoing transcatheter aortic valve replacement: A meta-analysis of randomized controlled trials and propensity score matched studies.

Family-based sexual health intervention for adolescents; A systematic review and meta-analysis (2024)
Journal Article
Mataraarachchi, D., Shepherd, T., Ariyadasa, G., Bajpai, R., Corp, N., & Paudyal, P. (2024). Family-based sexual health intervention for adolescents; A systematic review and meta-analysis. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.1057

Background Family-based interventions are important in promoting adolescent sexual health outcomes. However, the effectiveness of these interventions in promoting adolescent sexual and reproductive health (ASRH) in Lower and middle-income countries (... Read More about Family-based sexual health intervention for adolescents; A systematic review and meta-analysis.

Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry (2024)
Journal Article
Yera, H., Weight, N., Moledina, S. M., & Mamas, M. A. (2024). Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1559

Background Previous examination of data from the United Kingdom indicates no apparent ethnic disparity in the treatment of patients hospitalised with non-ST-segment elevation myocardial infarction (NSTEMI). However, it remains uncertain whether this... Read More about Ethnic disparity in the care and management of non-ST-segment elevation myocardial infarction and its impact on short-term and long-term survival: a long-term study of a national registry.

Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials (2024)
Journal Article
Lee, E., Tan, B., Chin, Y. H., Chan, Y. H., Ong, J., Goh, R. S. J., …Mamas, M. A. (2024). Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1556

Background and Purpose Major adverse cardiovascular event (MACE) is one of the most used composite outcomes in coronary artery disease (CAD) trials, though its lack of a standardised definition has led to ambiguity and challenges in its interpretatio... Read More about Insights into the reporting of major adverse cardiovascular events in coronary artery disease trials.

Association of lifes essential 8 and mortality among adults with and without CVD (2024)
Journal Article
Kobo, O., Kaur, G., Gulati, M., & Mamas, M. (2024). Association of lifes essential 8 and mortality among adults with and without CVD. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2698

Background Differences in the American Heart Association’s Life’s Essential 8 (LE8) score and its association with mortality based on the presence of clinically prevalent cardiovascular disease (CVD) has not been assessed previously. Methods Data fro... Read More about Association of lifes essential 8 and mortality among adults with and without CVD.

Sex differences in cancer incidence amongst people with cardiovascular disease: a large British population study (2024)
Journal Article
Thuemmler, R., Pana, T. A., Mamas, M. A., & Myint, P. K. (2024). Sex differences in cancer incidence amongst people with cardiovascular disease: a large British population study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.3166

Background
Studies have shown that patients with cardiovascular disease (CVD) have an incremental risk of death due to noncardiac causes. This is especially attributable to cancer developments during long term follow up. The two diseases share patho... Read More about Sex differences in cancer incidence amongst people with cardiovascular disease: a large British population study.

Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland (2024)
Journal Article
Pana, T., Mamas, M. A., Myint, P. K., & Dawson, D. (2024). Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2781

Background Sex differences in outcomes after myocardial infarction (MI) are of increasing interest. Differential receipt of evidence-based treatments may contribute to such disparities. Purpose In this study, we investigate sex differences in the bur... Read More about Sex differences in secondary prevention and outcomes post-myocardial infarction in Scotland.

Myocardial infarction risk across cancer subtypes - nationwide registry study (2024)
Journal Article
Shanmuganathan, J., Jacobsen, P. A. J., Schou, M. S., Torp Pedersen, C. T. P., Poulsen, L., Polcwiartek, C. B. P., …Kragholm, K. K. (2024). Myocardial infarction risk across cancer subtypes - nationwide registry study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1551

Background Progress in cancer treatments have significantly improved patient outcomes, leading to increased survival rates. However, patients with cancer continue to have higher rates of cardiovascular events an area that has traditionally not receiv... Read More about Myocardial infarction risk across cancer subtypes - nationwide registry study.

Co-producing COVID-19 health education resources with ethnic minority communities in the UK (2024)
Journal Article
Paudyal, P., Majeed-Hajaj, S., Khapangi Magar, N., Hughes, L., Keeling, D., Armes, J., …Cassell, J. (2024). Co-producing COVID-19 health education resources with ethnic minority communities in the UK. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.2052

Background Effective communication of relevant health information is challenging in elderly minority ethnic groups due to language barriers and cultural differences. During the COVID-19 pandemic, much of the public health guidance around COVID-19 was... Read More about Co-producing COVID-19 health education resources with ethnic minority communities in the UK.

Blood pressure lowering efficacy of antihypertensive drugs and their combinations: a systematic review and meta-analysis of 500 randomised, double-blind placebo-controlled trials (2024)
Journal Article
Wang, N., Salam, A., Pant, R., Kota, V., Dhurjati, R., Kumar, A., …Rodgers, A. (2024). Blood pressure lowering efficacy of antihypertensive drugs and their combinations: a systematic review and meta-analysis of 500 randomised, double-blind placebo-controlled trials. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2594

Background Each 1 mmHg reduction in systolic blood pressure (SBP) reduces the risk of major cardiovascular disease events by about 2%. However, there are currently no tools to provide randomised trial-derived estimates of blood pressure (BP)-lowering... Read More about Blood pressure lowering efficacy of antihypertensive drugs and their combinations: a systematic review and meta-analysis of 500 randomised, double-blind placebo-controlled trials.

Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid (2024)
Journal Article
Clutterbuck, D., Smyth, N., Begum, F., Chew-Graham, C., Mcgowan, A., Pantelic, M., …Alwan, N. A. (2024). Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.1822

Background Long Covid (also known as Post-COVID19 Condition or Post-COVID Syndrome) is characterised by persistent symptoms following SARSCoV2 infection not explained by other pathology. Some evidence suggests that people from marginalised communitie... Read More about Supporting Long Covid Care: a webtool to facilitate help-seeking among people with Long Covid.

Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study (2024)
Journal Article
Barlas, R., Pana, T., Myint, P., & Mamas, M. A. (2024). Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.1969

Background Acute Ischaemic stroke (AIS) is a common complication in infective endocarditis (IE) and associated is with high mortality. There is a paucity of data evaluating mechanical thrombectomy (MT) in patients with AIS secondary to IE. Our retros... Read More about Mechanical thrombectomy is associated with worse outcomes in infective endocarditis: a retrospective cohort study.