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All Outputs (21)

THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE (2021)
Presentation / Conference
Roffe, C., Bath, P., Warusevitane, A., Smith, C., Dixit, A., Sprigg, N., …Ogollah, R. (2021, November). THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE. Presented at UK Stroke Forum 2021, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mallen, Mason, Frisher, Mamas, Jordan, Marshall, …White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Hypoxic and pro-inflammatory priming of mesenchymal stem cell-derived extracellular vesicles to reduce disease severity and immune responses in inflammatory arthritis (2021)
Presentation / Conference
Kay, A. G., Treadwell, K., Roach, P., Morgan, R., Lodge, R., Hyland, M., …Kehoe, O. (2021, September). Hypoxic and pro-inflammatory priming of mesenchymal stem cell-derived extracellular vesicles to reduce disease severity and immune responses in inflammatory arthritis. Poster presented at 6th European Congress of Immunology, Virtual meeting

Novel biological therapies have revolutionised the management of Rheumatoid Arthritis (RA) but no cure currently exists. Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion... Read More about Hypoxic and pro-inflammatory priming of mesenchymal stem cell-derived extracellular vesicles to reduce disease severity and immune responses in inflammatory arthritis.

ACCEPTABILITY OF BISPHOSPHONATE TREATMENT REGIMENS FOR OSTEOPOROSIS: A QUALITATIVE SYSTEMATIC REVIEW (2021)
Presentation / Conference
Manning, F., Paskins, Z., Jinks, C., Cotterell, E., Sahota, O., Bishop, S., …Corp, N. (2021, August). ACCEPTABILITY OF BISPHOSPHONATE TREATMENT REGIMENS FOR OSTEOPOROSIS: A QUALITATIVE SYSTEMATIC REVIEW. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020)

Objective: To investigate the acceptability of different bisphosphonates treatment regimens for osteoporosis among patients and clinicians. Methods: A systematic review of qualitative research exploring patients’ and clinicians’ views of the accep... Read More about ACCEPTABILITY OF BISPHOSPHONATE TREATMENT REGIMENS FOR OSTEOPOROSIS: A QUALITATIVE SYSTEMATIC REVIEW.

Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy (2021)
Presentation / Conference
Phannajit, J., Kanjanabuch, T., Ponpirul, K., Narenpitak, S., Puapatanakul, P., Johnson, D. W., …PDOPPS Steering Committee, O. B. O. T. (2021, August). Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy. Presented at 19th Asian Pacific Congress of Nephrology, Virtual Congress

Background: There are conflicting results concerning the survival differences between patients with and without hemodialysis (HD) transfer (HDT). Using the Peritoneal Dialysis (PD) Outcomes and Practice Patterns Study (PDOPPS), a prospective cohort s... Read More about Unplanned peritoneal dialysis (PD) and patient survival under Thailand “PD first” policy.

SHOULD THE PRESENCE OF NEURODEGENERATIVE DISEASE ALTER OUR MANAGEMENT AND UNDERSTANDING OF PSYCHIATRIC COMORBIDITIES? (2021)
Presentation / Conference
Blake, J., List, P., & El-Nimr, G. (2021, July). SHOULD THE PRESENCE OF NEURODEGENERATIVE DISEASE ALTER OUR MANAGEMENT AND UNDERSTANDING OF PSYCHIATRIC COMORBIDITIES?

As people are living longer, we are seeing more neurodegenerative diseases (NDs). NDs have both neurological and psychiatric manifestations. Depression and anxiety are common comorbidities in Alzheimers and Parkinsons disease. The diagnosis and inter... Read More about SHOULD THE PRESENCE OF NEURODEGENERATIVE DISEASE ALTER OUR MANAGEMENT AND UNDERSTANDING OF PSYCHIATRIC COMORBIDITIES?.

Combining expert judgment and psychometric information to create the Global Scale for Early Development (GSED) (2021)
Presentation / Conference
McCray, G., Gladstone, M., Cavallera, V., McCoy, D., Waldman, M., Eekhout, I., …Weber, A. (2021, June). Combining expert judgment and psychometric information to create the Global Scale for Early Development (GSED). Paper presented at Proceedings of the Patient Reported Outcome Measures (PROMs) Research Conference, Sheffield, UK

Background: The Global Scale for Early Development (GSED) a global and culturally neutral measure of child development under 3 years of age is designed to allow comparisons within and across countries. The project has been undertaken by an experience... Read More about Combining expert judgment and psychometric information to create the Global Scale for Early Development (GSED).

37 Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and scai criteria fit for purpose? (2021)
Presentation / Conference
Hinton, J., Augustine, M., Gabara, L., Mariathas, M., Allan, R., Borca, F., …Curzen, N. (2021, June). 37 Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and scai criteria fit for purpose?. Paper presented at British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021

Introduction The diagnosis and clinical implication of periprocedural myocardial infarction (PPMI) following coronary artery bypass grafting (CABG) is contentious, especially given its importance in the interpretation of trial data. Two accepted defi... Read More about 37 Incidence and one year outcome of periprocedural myocardial infarction following cardiac surgery: are the universal definition and scai criteria fit for purpose?.

184 Association between high-sensitivity troponin and one year mortality in 20,000 consecutive hospital patients undergoing a blood test for any reason (2021)
Presentation / Conference
Hinton, J., Mariathas, M., Gabara, L., Allan, R., Nicholas, Z., Kwok, C. S., …Curzen, N. (2021, June). 184 Association between high-sensitivity troponin and one year mortality in 20,000 consecutive hospital patients undergoing a blood test for any reason. Paper presented at British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021

Introduction High sensitivity troponin (hs-cTn) concentrations above the manufacturer recommended upper limit of normal (ULN) are seen frequently in patients without a clinical presentation consistent with an acute coronary syndrome. There is increas... Read More about 184 Association between high-sensitivity troponin and one year mortality in 20,000 consecutive hospital patients undergoing a blood test for any reason.

TRENDS OF IN-HOSPITAL AND 30-DAY MORTALITY AFTER PERCUTANEOUS CORONARY INTERVENTION IN ENGLAND BEFORE AND AFTER THE COVID-19 ERA (2021)
Presentation / Conference
Mohamed, M., Curzen, N., Ludman, P., Rashid, M., Shoaib, A., de Belder, M., …Mamas, M. (2021, May). TRENDS OF IN-HOSPITAL AND 30-DAY MORTALITY AFTER PERCUTANEOUS CORONARY INTERVENTION IN ENGLAND BEFORE AND AFTER THE COVID-19 ERA. Poster presented at ACC.21, Virtual

Background Public reporting of percutaneous coronary intervention (PCI) outcomes is a performance metric and a requirement in many healthcare systems. There are inconsistent data on the causes of death after PCI, and what proportion of these are att... Read More about TRENDS OF IN-HOSPITAL AND 30-DAY MORTALITY AFTER PERCUTANEOUS CORONARY INTERVENTION IN ENGLAND BEFORE AND AFTER THE COVID-19 ERA.

Metformin use and the risk of total knee replacement among diabetic patients in primary care (2021)
Presentation / Conference
Sit, R., Lai, F., Yip, B., Hunter, D., Rabago, D., Mallen, C., & Wong, S. (2021, April). Metformin use and the risk of total knee replacement among diabetic patients in primary care. Presented at Virtual 2021 OARSI World Congress on Osteoarthritis, Virtual

Purpose: Metformin, apart from its glucose lowering and weight reduction effects, has recently been shown to modulate meta-inflammation, an important pathogenesis in knee osteoarthritis (OA). We aim to study the association between regular metformin... Read More about Metformin use and the risk of total knee replacement among diabetic patients in primary care.