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Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial (2016)
Report
Richards, D. A., Bower, P., Chew-Graham, C., Gask, L., Lovell, K., Cape, J., …Russell, A. Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial. Medical Research Council, HTA, NIHR

Background
Collaborative care is effective for depression management in the USA. There is little UK evidence on its clinical effectiveness and cost-effectiveness.

Objective
To determine the clinical effectiveness and cost-effectiveness of collab... Read More about Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial.

Integrating mental health into primary care for post-conflict populations: a pilot study (2016)
Journal Article
Siriwardhana, C., Adikari, A., Jayaweera, K., Abeyrathna, B., & Sumathipala, A. (2016). Integrating mental health into primary care for post-conflict populations: a pilot study. International Journal of Mental Health Systems, 10, Article 12. https://doi.org/10.1186/s13033-016-0046-x

Background
Mental health care in post-conflict settings is often not prioritized, despite its important public health role. There is a salient gap in integrating mental health into primary care, especially in post-conflict settings. In the post-conf... Read More about Integrating mental health into primary care for post-conflict populations: a pilot study.

Self-management of health care behaviors for COPD: a systematic review and meta-analysis (2016)
Journal Article
(2016). Self-management of health care behaviors for COPD: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease, 305 -326. https://doi.org/10.2147/COPD.S90812

PURPOSE: This systematic review aimed to identify the most effective components of interventions to facilitate self-management of health care behaviors for patients with COPD. PROSPERO registration number CRD42011001588. METHODS: We used standard rev... Read More about Self-management of health care behaviors for COPD: a systematic review and meta-analysis.

Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study. (2016)
Journal Article
Chew-Graham, C. (2016). Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study. BMC Health Services Research, 58 -?. https://doi.org/10.1186/s12913-016-1298-5

BACKGROUND: Many people with mental distress are disadvantaged because care is not available or does not address their needs. In order to increase access to high quality primary mental health care for under-served groups, we created a model of care w... Read More about Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study..

Musculoskeletal pain in children and adolescents (2016)
Journal Article
Dunn. (2016). Musculoskeletal pain in children and adolescents. Brazilian Journal of Physical Therapy, 275 - 284. https://doi.org/10.1590/bjpt-rbf.2014.0149

INTRODUCTION: Musculoskeletal (MSK) pain in children and adolescents is responsible for substantial personal impacts and societal costs, but it has not been intensively or systematically researched. This means our understanding of these conditions is... Read More about Musculoskeletal pain in children and adolescents.

Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial. (2016)
Journal Article
(2016). Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial. Pilot and Feasibility Studies, 10 - ?. https://doi.org/10.1186/s40814-016-0051-5

BACKGROUND: Evidence suggests acupuncture may be effective for treating the symptoms of knee osteoarthritis. Offering this in a group setting may offer cost savings. The aim of this study was to establish the feasibility of a definitive trial to asse... Read More about Western medical acupuncture in a group setting for knee osteoarthritis: results of a pilot randomised controlled trial..

UK National Survey of Practice Patterns of Fluid Volume Management in Haemodialysis Patients: A Need for Evidence (2016)
Journal Article
Dasgupta, I., Farrington, K., Davies, S. J., Davenport, A., & Mitra, S. (2016). UK National Survey of Practice Patterns of Fluid Volume Management in Haemodialysis Patients: A Need for Evidence. Blood Purification, 41(4), 324-331. https://doi.org/10.1159/000444246

Background: Fluid management in haemodialysis (HD) affects patient experience, morbidity and mortality. Standards for best practice are lacking. A national survey of the United Kingdom was undertaken to define prevalent practice. Methods: An online q... Read More about UK National Survey of Practice Patterns of Fluid Volume Management in Haemodialysis Patients: A Need for Evidence.

A randomised trial evaluating anakinra in early active rheumatoid arthritis. (2016)
Journal Article
Scott, I. C., Ibrahim, F., Simpson, G., Kowalczyk, A., White-Alao, B., Hassell, A., …Scott, D. L. (2016). A randomised trial evaluating anakinra in early active rheumatoid arthritis. Clinical and Experimental Rheumatology, 34(1), 88-93

OBJECTIVES:
The effectiveness of anakinra (interleukin-1 receptor antagonist) in early rheumatoid arthritis (RA) is unknown. We evaluated the efficacy of anakinra (combined with methotrexate) in a randomised clinical trial of early active RA patient... Read More about A randomised trial evaluating anakinra in early active rheumatoid arthritis..

ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country (2016)
Journal Article
Bajpai. (2016). ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country. Pediatric Blood and Cancer, 1024 - 1030. https://doi.org/10.1002/pbc.25935

Background
As Hodgkin lymphoma (HL) is a highly curable malignancy, most current pediatric trials focus on strategies aimed at reducing late effects of therapy. We report our results with doxorubicin, bleomycin, vinblastine, dacarbazine (ABVD) thera... Read More about ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country.

Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial (2016)
Journal Article
Tallon, D., Wiles, N., Campbell, J., Chew-Graham, C., Dickens, C., Macleod, U., …Kessler, D. (2016). Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial. Trials, 17, 66. https://doi.org/10.1186/s13063-016-1199-2

Background
People with depression are usually managed in primary care and antidepressants are often the first-line treatment, but only one third of patients respond fully to a single antidepressant. This paper describes the protocol for a randomised... Read More about Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): study protocol for a randomised controlled trial.

The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids (2016)
Journal Article
van Middelkoop, M., Arden, N. K., Atchia, I., Birrell, F., Chao, J., Rezende, M. U., …Bierma-Zeinstra, S. M. A. (2016). The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids. Osteoarthritis and Cartilage, 24(7), 1143-1152. https://doi.org/10.1016/j.joca.2016.01.983

Knowing, planning for and fearing death: Do adults with intellectual disability and disability staff differ? (2016)
Journal Article
(2016). Knowing, planning for and fearing death: Do adults with intellectual disability and disability staff differ?. Research in Developmental Disabilities, 47 - 59. https://doi.org/10.1016/j.ridd.2015.11.016

BACKGROUND: Adults with intellectual disability (ID) are thought to understand less about death than the general population but there is no available research demonstrating this. Further, the detail of any possible differences in understanding is unk... Read More about Knowing, planning for and fearing death: Do adults with intellectual disability and disability staff differ?.

Qualitative exploration of illness perceptions of Rheumatoid Arthritis in the General Public (2016)
Journal Article
Mallen. (2016). Qualitative exploration of illness perceptions of Rheumatoid Arthritis in the General Public. Musculoskeletal Care, 13-22. https://doi.org/10.1002/msc.1135

Treating patients with rheumatoid arthritis (RA) within three months of symptom onset leads to significantly improved outcomes. However, many people delay seeking medical attention. In order to understand the reasons for this delay, it is important t... Read More about Qualitative exploration of illness perceptions of Rheumatoid Arthritis in the General Public.

Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study. (2016)
Journal Article
(2016). Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study. BMJ Open, e009981. https://doi.org/10.1136/bmjopen-2015-009981

OBJECTIVES

Health systems with strong primary care tend to have better population outcomes, but in many countries demand for care is growing. We sought to identify mechanisms of primary care that influence premature mortality.

DESIGN

We deve... Read More about Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study..

Epidemiology of Shoe Wearing Patterns Over Time in Older Women: Associations With Foot Pain and Hallux Valgus (2016)
Journal Article
Menz, H. B., Roddy, E., Marshall, M., Thomas, M. J., Rathod, T., Peat, G. M., & Croft, P. R. (2016). Epidemiology of Shoe Wearing Patterns Over Time in Older Women: Associations With Foot Pain and Hallux Valgus. Journals of Gerontology, Series A, 71(12), 1682 - 1687. https://doi.org/10.1093/gerona/glw004

Background:
Foot problems are prevalent in older women and are thought to be associated with footwear. This study examined women’s shoe wearing patterns over time and evaluated associations between footwear characteristics and foot pain and hallux v... Read More about Epidemiology of Shoe Wearing Patterns Over Time in Older Women: Associations With Foot Pain and Hallux Valgus.

Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation. (2016)
Journal Article
(2016). Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation. Health Technology Assessment, i - 190. https://doi.org/10.3310/hta20120

BACKGROUND: Unprovoked first venous thromboembolism (VTE) is defined as VTE in the absence of a temporary provoking factor such as surgery, immobility and other temporary factors. Recurrent VTE in unprovoked patients is highly prevalent, but easily p... Read More about Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation..

Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the multicentre osteoarthritis study (2016)
Journal Article
(2016). Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the multicentre osteoarthritis study. Osteoarthritis and Cartilage, 1160-1166. https://doi.org/10.1016/j.joca.2016.01.981

Objectives
To investigate changes in cartilage damage and bone marrow lesions (BMLs) on MRI in the patellofemoral and tibiofemoral joints (TFJs) over 7 years.

Methods
The Multicenter Osteoarthritis (MOST) Study is a cohort study of persons aged... Read More about Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the multicentre osteoarthritis study.