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All Outputs (395)

Defining acute flares in knee osteoarthritis: A systematic review (2018)
Journal Article
Thomas, M., Peat, G., & Parry, E. (2018). Defining acute flares in knee osteoarthritis: A systematic review. BMJ Open, 8(7), Article e019804. https://doi.org/10.1136/bmjopen-2017-019804

OBJECTIVE: To identify and critically synthesise definitions of acute flares in knee osteoarthritis (OA) reported in the medical literature. DESIGN: Systematic review and narrative synthesis. We searched Medline, EMBASE, Web of science and six other... Read More about Defining acute flares in knee osteoarthritis: A systematic review.

Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review (2018)
Journal Article
Jordan, Babatunde, & Paskins. (2018). Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review. Archives of Osteoporosis, 13(55), https://doi.org/10.1007/s11657-018-0470-4

This systematic review identified patients have unmet information needs about the nature of osteoporosis, medication, self-management and follow-up. Clinician knowledge and attitudes appear to be of key importance in determining whether these needs a... Read More about Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review.

Real world practice level data analysis confirms link between variability within blood glucose monitoring strip and glycosylated haemoglobin in type 1 diabetes (2018)
Presentation / Conference Contribution
Stedman, M., Young, R. J., Moreno, G., Lunt, M., Livingston, M., Laing, I., Heald, A., Gadsby, R., Fryer, A., & Anderson, S. (2018, December). Real world practice level data analysis confirms link between variability within blood glucose monitoring strip and glycosylated haemoglobin in type 1 diabetes

Erratum to pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis (2018)
Journal Article
Solo, K., Lavi, S., Choudhury, T., Martin, J., Nevis, I. F., Kwok, C. S., Kotronias, R. A., Nishina, N., Sponga, S., Ayan, D., Tzemos, N., Mamas, M. A., & Bagur, R. (2018). Erratum to pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis. Journal of thoracic disease, 10(12), E860-E860. https://doi.org/10.21037/jtd.2018.10.120

Pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis

In the article that appeared on Page 3444-3459, Vol 10, No 6 (June 2018) Issue of the Journal of Thoracic Disease (J... Read More about Erratum to pre-operative use of aspirin in patients undergoing coronary artery bypass grafting: a systematic review and updated meta-analysis.

Gabapentinoid prescriptions in patients with osteoarthritis: an analysis of data from the Clinical Practice Research Datalink (2018)
Thesis
Appleyard, T. Gabapentinoid prescriptions in patients with osteoarthritis: an analysis of data from the Clinical Practice Research Datalink. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417947

Amid a substantial rise in gabapentin and pregabalin (gabapentinoid) prescribing and increasing concerns with their potential for misuse and diversion, there are anecdotal reports of their use for osteoarthritis. The aim of my thesis was to understan... Read More about Gabapentinoid prescriptions in patients with osteoarthritis: an analysis of data from the Clinical Practice Research Datalink.

Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study (2018)
Thesis
Nell, M. Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417946

Low back pain (LBP) is a common, often long-term problem which occurs at all stages of life from childhood to old age. This thesis focuses on persistent LBP in ‘emerging adulthood’ (18-29 years), a developmental stage characterised by delayed subscri... Read More about Persistent back pain in emerging adults: an analysis of the 1970 British Birth Cohort Study.

Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain (2018)
Thesis
Harrisson, S. A. Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. (Thesis). Keele University. https://keele-repository.worktribe.com/output/412647

Neuropathic pain (pain caused by nerve damage) is considered challenging to manage. One of the most common neuropathic pain conditions is believed to be the presence of sciatica in low back-related leg pain (LBLP). A systematic review of the literatu... Read More about Epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain.

‘Through the looking glass’ - primary care consultations, work and health: a qualitative study (2018)
Thesis
Dalgarno, E. L. ‘Through the looking glass’ - primary care consultations, work and health: a qualitative study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/412293

Musculoskeletal conditions are believed to cost UK society approximately £7.4 billion per year, with 30 million working days lost each year due to musculoskeletal conditions. Currently, within the UK, sickness certification can be self-certified for... Read More about ‘Through the looking glass’ - primary care consultations, work and health: a qualitative study.

Osteoarthritis: Treatment (2018)
Book Chapter
Edwards, J., Paskins, Z., & Dziedzic, K. (2018). Osteoarthritis: Treatment. In EULAR Textbook on Rheumatic Diseases. (3). BMJ Publishing Group

Prevalence of foot pain across an international consortium of population based cohorts. (2018)
Journal Article
Gates, L. S., Arden, N. K., Hannan, M. T., Roddy, E., Gill, T. K., Hill, C. L., Dufour, A. B., Rathod-Mistry, T., Thomas, M. J., Menz, H. B., Bowen, C. J., & Golightly, Y. M. (2019). Prevalence of foot pain across an international consortium of population based cohorts. Arthritis Care and Research, 71(5), 661-670. https://doi.org/10.1002/acr.23829

OBJECTIVE:
Despite the potential burden of foot pain, some of the most fundamental epidemiological questions surrounding the foot remain poorly explored. The prevalence of foot pain has proved difficult to compare across existing studies due to var... Read More about Prevalence of foot pain across an international consortium of population based cohorts..

Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care. (2018)
Journal Article
Hill, J. (2018). Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care. BMJ Open, https://doi.org/10.1136/bmjopen-2018-021748

OBJECTIVES: The predictive ability of the STarT Back Tool (SBT) has not yet been examined among acute/subacute back and/or neck pain in a primary care setting in respect to health-related quality of life (HRQoL) and work ability outcomes. The aim of... Read More about Can the STarT Back Tool predict health-related quality of life and work ability after an acute/subacute episode with back or neck pain? A psychometric validation study in primary care..

Developing a video-based method to compare and adjust examiner effects in fully nested OSCEs (2018)
Journal Article
Yeates, P., Cope, N., Hawarden, A., Bradshaw, H., McCray, G., & Homer, M. (2019). Developing a video-based method to compare and adjust examiner effects in fully nested OSCEs. Medical Education, 53(3), 250-263. https://doi.org/10.1111/medu.13783

Background:
Whilst averaging across multiple examiners judgements reduces unwanted overall score variability in Objective Structured Clinical Examinations (OSCE), designs involving several parallel circuits of the OSCE require that different examin... Read More about Developing a video-based method to compare and adjust examiner effects in fully nested OSCEs.

Effect on hospital length of stay of tourniquet use during internal fixation of ankle fracture: randomized controlled trial (2018)
Journal Article
Sim, J., Grocott, N., Majeed, H., & McClelland, D. (2019). Effect on hospital length of stay of tourniquet use during internal fixation of ankle fracture: randomized controlled trial. Journal of Foot and Ankle Surgery, 58(1), 114-118. https://doi.org/10.1053/j.jfas.2018.08.023

Approximately 50% of ankle fractures require internal fixation. A tourniquet is often employed to create a bloodless operative field, but its effect on hospital length of stay (LOS) is unclear. This paper reports a parallel-group observer-blinded ran... Read More about Effect on hospital length of stay of tourniquet use during internal fixation of ankle fracture: randomized controlled trial.

HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis (2018)
Journal Article
Dand, N., Duckworth, M., Baudry, D., Russell, A., Curtis, C. J., Hyuck Lee, S., Evans, I., Mason, K., Alsharqi, A., Becher, G., David Burden, A., Goodwin, R. G., McKenna, K., Murphy, R., Perera, G. K., Rotarescu, R., Wahie, S., Wright, A., Reynolds, N. J., Warren, R. B., …Study Group, B. (2019). HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis. Journal of Allergy and Clinical Immunology, 143(6), 2120-2130. https://doi.org/10.1016/j.jaci.2018.11.038

BACKGROUND: Biologic therapies can be highly effective for the treatment of severe psoriasis, but response for individual patients can vary according to drug. Predictive biomarkers to guide treatment selection could improve patient outcomes and treat... Read More about HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis.

Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease (2018)
Journal Article
Mamas. (2018). Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease. Journal of the American Medical Association, https://doi.org/10.1001/jamanetworkopen.2018.5489

IMPORTANCE
In heart failure (HF), chronic obstructive pulmonary disease (COPD) increases the risk of poor outcomes, but the effect of COPD severity is unknown. This information is important for early intervention tailored to the highest-risk groups.... Read More about Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.

The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners (2018)
Journal Article
Chew-Graham, C., Shepherd, T., Burroughs, H., Dixon, K., & Kessler, D. (2018). The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners. BMC Family Practice, https://doi.org/10.1186/s12875-018-0877-4

BACKGROUND: Depression is the leading cause of disability worldwide, and is a major contributor to the overall global burden of disease. The number of prescriptions for antidepressants has risen dramatically in recent years yet up to 50% of patients... Read More about The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners.

Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis. (2018)
Journal Article
(2018). Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis. The Lancet Gastroenterology & Hepatology, 825 - 836. https://doi.org/10.1016/S2468-1253%2818%2930301-7

BACKGROUND: In patients with rectal cancer who achieve clinical complete response after neoadjuvant chemoradiotherapy, watch and wait is a novel management strategy with potential to avoid major surgery. Study-level meta-analyses have reported wide v... Read More about Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis..

The temporal relationship between cancer and adult onset anti-transcriptional intermediary factor 1 antibody–positive dermatomyositis (2018)
Journal Article
Oldroyd, A., Sergeant, J. C., New, P., McHugh, N. J., Betteridge, Z., Lamb, J. A., Ollier, W. E., Cooper, R. G., Chinoy, H., Ahmed, Y., Armstrong, R., Bernstein, R., Black, C., Bowman, S., Bruce, I., Butler, R., Carty, J., Chattopadhyay, C., Chelliah, E., Clarke, F., …UKMyoNet. (2019). The temporal relationship between cancer and adult onset anti-transcriptional intermediary factor 1 antibody–positive dermatomyositis. Rheumatology, 58(4), 650-655. https://doi.org/10.1093/rheumatology/key357