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Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis. (2022)
Journal Article
Mamas. (2022). Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis. https://doi.org/10.1080/07853890.2022.2059559

Atherosclerotic heart disease is the leading cause of mortality and morbidity in the USA. Low density lipoprotein (LDL) has been the target for many hypolipidemic agents to modify atherosclerotic risk. Bempedoic acid is a novel hypolipidemic drug tha... Read More about Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis..

Negotiating agency and belonging during the first lockdown of the COVID-19 pandemic: an interview study among older adults in England, UK. (2022)
Journal Article
Wenning, B., Polidano, K., Mallen, C., & Dikomitis, L. (2022). Negotiating agency and belonging during the first lockdown of the COVID-19 pandemic: an interview study among older adults in England, UK. BMJ Open, e060405 - ?. https://doi.org/10.1136/bmjopen-2021-060405

OBJECTIVES: The aim of this study was to explore the agency of older adults and their strategies to restructure ways of being and belonging in a rapidly and radically changed social environment during the UK's first COVID-19 lockdown in Spring 2020.... Read More about Negotiating agency and belonging during the first lockdown of the COVID-19 pandemic: an interview study among older adults in England, UK..

The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis (2022)
Journal Article
Mughal, F., Troya, M., Dikomitis, L., Tierney, S., Corp, N., Evans, N., …Chew-Graham, C. (2022). The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis. EClinicalMedicine, 48, 101437 - 101437. https://doi.org/10.1016/j.eclinm.2022.101437

Self-harm in young people is a serious international health concern that impacts on those providing informal support: the supporting individuals of young people. We aimed to highlight the experiences, views, and needs of these supporting individuals... Read More about The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis.

“I Do Not Have to Hurt My Body Anymore”: Reproductive Chronicity and Sterilization as Ambivalent Care in Rural North India (2022)
Journal Article
Lukšaitė, E. (2022). “I Do Not Have to Hurt My Body Anymore”: Reproductive Chronicity and Sterilization as Ambivalent Care in Rural North India. Medical Anthropology Quarterly, 36(3), 312-328. https://doi.org/10.1111/maq.12709

Drawing on 18 months of ethnographic fieldwork in rural Rajasthan, India, I examine women's narratives of chronic reproductive suffering and the practices they employed to relieve it. Cumulative effects of adverse and ordinary reproductive events and... Read More about “I Do Not Have to Hurt My Body Anymore”: Reproductive Chronicity and Sterilization as Ambivalent Care in Rural North India.

Quantifying the population burden of musculoskeletal disorders, including impact on sickness absence: analysis of national Scottish data (2022)
Journal Article
Hill, J. (2022). Quantifying the population burden of musculoskeletal disorders, including impact on sickness absence: analysis of national Scottish data. Rheumatology Advances in Practice, https://doi.org/10.1093/rap/rkac030

Objectives Musculoskeletal disorders (MSDs) account for the greatest burden of years lived with disability globally. To prevent disability, good-quality services need to be commissioned, appropriate for local need. We analysed data collected systema... Read More about Quantifying the population burden of musculoskeletal disorders, including impact on sickness absence: analysis of national Scottish data.

Suicide and death by other causes among patients with a severe mental illness: cohort study comparing risks among patients discharged from inpatient care v. those treated in the community. (2022)
Journal Article
Musgrove, R., Carr, M., Kapur, N., Chew-Graham, C., Mughal, F., Ashcroft, D., & Webb, R. (2022). Suicide and death by other causes among patients with a severe mental illness: cohort study comparing risks among patients discharged from inpatient care v. those treated in the community. Epidemiology and Psychiatric Sciences, e32 - ?. https://doi.org/10.1017/S2045796022000075

AIMS: People diagnosed with a severe mental illness (SMI) are at elevated risk of dying prematurely compared to the general population. We aimed to understand the additional risk among people with SMI after discharge from inpatient psychiatric care,... Read More about Suicide and death by other causes among patients with a severe mental illness: cohort study comparing risks among patients discharged from inpatient care v. those treated in the community..

Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis (2022)
Journal Article
Mamas. (2022). Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 2581 - 2581. https://doi.org/10.3390/jcm11092581

The following study aimed to systematically review and meta-analyse the literature on the relations between markers of nutritional status and long-term mortality, recurrence and all-cause hospital readmission following myocardial infarction (MI). Med... Read More about Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis.

Young people who have fallen through the mental health transition gap: a qualitative study on primary care support (2022)
Journal Article
Appleton, R., Loew, J., & Mughal, F. (2022). Young people who have fallen through the mental health transition gap: a qualitative study on primary care support. British Journal of General Practice (BJGP), BJGP.2021.0678 - BJGP.2021.0678. https://doi.org/10.3399/bjgp.2021.0678

Background Owing to poor continuity of care between child and adult mental health services, young people are often discharged to their GP when they reach the upper boundary of child and adolescent mental health services (CAMHS). This handover is poor... Read More about Young people who have fallen through the mental health transition gap: a qualitative study on primary care support.

Image Guided Needle Biopsies for Musculoskeletal Soft Tissue Lesions: A 9-Year Analysis of Non-Diagnostic Biopsies (2022)
Journal Article
Morris, R., Winn, N., Singh, J., Tyrrell, P., Kaur, S., Amary, F., & Cool, P. (2022). Image Guided Needle Biopsies for Musculoskeletal Soft Tissue Lesions: A 9-Year Analysis of Non-Diagnostic Biopsies. Journal of Orthopaedic Oncology, 8(3), Article 168. https://doi.org/10.4172/2472-016X.1000168

Background: Non-diagnostic (ND) musculoskeletal biopsies of soft tissue lesions can increase patient anxiety and delay definitive diagnosis and treatment. It is thought the specific histotype of the lesion may influence accuracy of the biopsy. This s... Read More about Image Guided Needle Biopsies for Musculoskeletal Soft Tissue Lesions: A 9-Year Analysis of Non-Diagnostic Biopsies.

Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention. (2022)
Journal Article
Mamas. (2022). Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention. https://doi.org/10.1016/j.carrev.2021.08.018

BACKGROUND: The aim was to determine the impact of diabetes mellitus (DM) on outcomes after percutaneous coronary intervention (PCI). There is limited data on the impact of DM and its subtypes among patients who underwent PCI during hospitalization.... Read More about Differential Impact of Type 1 and Type 2 Diabetes Mellitus on Outcomes Among 1.4 Million US Patients Undergoing Percutaneous Coronary Intervention..

Burden of allergic disease among ethnic minority groups in high-income countries (2022)
Journal Article
Jones, C. J., Paudyal, P., West, R. M., Mansur, A. H., Jay, N., Makwana, N., …Krishna, M. T. (2022). Burden of allergic disease among ethnic minority groups in high-income countries. Clinical and Experimental Allergy, 604 - 615. https://doi.org/10.1111/cea.14131

The COVID-19 pandemic raised acute awareness regarding inequities and inequalities and poor clinical outcomes amongst ethnic minority groups. Studies carried out in North America, the UK and Australia have shown a relatively high burden of asthma and... Read More about Burden of allergic disease among ethnic minority groups in high-income countries.

Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission (2022)
Journal Article
Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., de Silva, T. I., Siggins, M. K., …Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators, I. S. A. R. A. E. I. (2022). Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission. Open Forum Infectious Diseases, 9(5), https://doi.org/10.1093/ofid/ofac179

Abstract Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium Wo... Read More about Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission.

In defence of the bioethics scoping review: Largely systematic literature reviewing with broad utility. (2022)
Journal Article
Parsons. (2022). In defence of the bioethics scoping review: Largely systematic literature reviewing with broad utility. Bioethics, 423 - 433. https://doi.org/10.1111/bioe.12991

There is growing interest in the possible role of systematic methods of reviewing literature in bioethics. This has arisen alongside the growth of empirical bioethics and a general push towards introducing some level of rigour and reproducibility int... Read More about In defence of the bioethics scoping review: Largely systematic literature reviewing with broad utility..

P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article
Paskins, Z., Bullock, L., Manning, F., Bishop, S., Campbell, P., Cottrell, E., …Ryan, S. (2022). P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.058

Abstract Background/Aims The COVID-19 pandemic led to the widespread adoption of remote consultations. Whilst remote consultations offer many potential advantages to patients and healthcare services, they are unlikely to be suitable for all. Guidanc... Read More about P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

P182 Health literacy and gout characteristics in a primary care cohort (2022)
Journal Article
Watson, L., Protheroe, J., Mallen, C., Muller, S., & Roddy, E. (2022). P182 Health literacy and gout characteristics in a primary care cohort. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.181

Abstract Background/Aims Gout is the most common inflammatory arthritis, affecting 2.5% of the UK population. It is often suboptimally managed, despite the availability of effective urate-lowering therapy. Health literacy has been conceptualised to... Read More about P182 Health literacy and gout characteristics in a primary care cohort.

P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies (2022)
Journal Article
Roddy, E., Bajpai, R., Forrester, H., Partington, R., Mallen, C. D., Clarson, L., …Muller, S. (2022). P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.144

Abstract Background/Aims Initiating urate-lowering therapy for gout commonly triggers a gout flare and hence co-prescription of colchicine or non-steroidal anti-inflammatory drug (NSAID) prophylaxis is recommended. However, little is known about the... Read More about P145 Safety of colchicine or NSAID prophylaxis when initiating allopurinol for gout: propensity score-matched cohort studies.

P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey (2022)
Journal Article
Roddy, Hider, Muller, & Paskins. (2022). P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.063

Abstract Background/Aims Concerns about the risk of COVID-19 infection led to guidelines advocating shielding for many people with inflammatory conditions. We aimed to assess the impact of the pandemic on the self-reported physical and mental health... Read More about P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey.

P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement (2022)
Journal Article
Paskins. (2022). P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement. Rheumatology, https://doi.org/10.1093/rheumatology/keac133.007

Abstract Background/Aims Osteoporosis is a burdensome disease internationally, that is commonly diagnosed following fragility fracture. In line with national guidance, in 2018 the North Staffordshire Fracture Liaison Service (FLS) changed their mana... Read More about P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement.