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THE SUBGROUP EFFECTS OF NON-SURGICAL AND NON-PHARMACOLOGICAL TREATMENT OF PATIENTS WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK (2022)
Journal Article
Thissen, G., van Middelkoop, M., Colaris, J., Selles, R., Dziedzic, K., Nicholls, E., & Bierma-Zeinstra, S. (2022). THE SUBGROUP EFFECTS OF NON-SURGICAL AND NON-PHARMACOLOGICAL TREATMENT OF PATIENTS WITH HAND OSTEOARTHRITIS - A PROTOCOL FOR AN INDIVIDUAL PATIENT DATA META-ANALYSIS IN THE OA TRIAL BANK. Osteoarthritis and Cartilage, 30(S1), S423. https://doi.org/10.1016/j.joca.2022.02.576

Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis (2022)
Journal Article
Helliwell, T., Wright, T., Mughal, F., Babatunde, O., Dikomitis, L., & Mallen, C. (2022). Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis. Bulletin of the World Health Organization, 385 - 401A. https://doi.org/10.2471/blt.22.288300

Objective To estimate the prevalence of burnout among primary health-care professionals in low- and middle-income countries and to identify factors associated with burnout. Methods We systematically searched nine databases up to February 2022 to... Read More about Burnout among primary health-care professionals in low- and middle-income countries: systematic review and meta-analysis.

Clinical trial management: a profession in crisis? (2022)
Journal Article
Mitchell, E., Goodman, K., Wakefield, N., Cochran, C., Cockayne, S., Connolly, S., …Youssouf, N. (2022). Clinical trial management: a profession in crisis?. Trials, 23(1), Article ARTN 357. https://doi.org/10.1186/s13063-022-06315-8

Clinical trial managers play a vital role in the design and conduct of clinical trials in the UK. There is a current recruitment and retention crisis for this specialist role due to a complex set of factors, most likely to have come to a head due to... Read More about Clinical trial management: a profession in crisis?.

Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals (2022)
Journal Article
Mamas. (2022). Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals. The Lancet Regional Health Europe, https://doi.org/10.1016/j.lanepe.2022.100386

Background Population-based studies of atrial fibrillation (AF) incidence are needed to inform health-service planning, but evidence is conflicting. We assessed trends of AF incidence in a large general population cohort from England. Methods We used... Read More about Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3·4 million individuals.

Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation? (2022)
Journal Article
Hoban, K. A., Downie, S., Adamson, D. J., MacLean, J. G., Cool, P., & Jariwala, A. C. (2022). Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation?. https://doi.org/10.1016/j.jseint.2022.03.006

The aim of this study was to investigate the reproducibility, reliability and accuracy of Mirels’s score in upper limb bony metastatic disease and validate its use in predicting pathological fractures. Methods 45 patients with upper limb bony metasta... Read More about Mirels’ score for upper limb metastatic lesions: do we need a different cutoff for recommending prophylactic fixation?.

Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. (2022)
Journal Article
Sokhal, B., Matetić, A., Bharadwaj, A., Helliwell, T., Abhishek, A., Mallen, C., …Mamas, M. (2022). Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis. American Journal of Cardiology, 12-19. https://doi.org/10.1016/j.amjcard.2022.03.034

This study analyzed the characteristics, management, and outcomes of patients with polymyalgia rheumatica (PMR) hospitalized with acute myocardial infarction (AMI), including sensitivity analysis for presence of giant cell arteritis (GCA). Using the... Read More about Treatment and Outcomes of Acute Myocardial Infarction in Patients With Polymyalgia Rheumatica With and Without Giant Cell Arteritis..

P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study (2022)
Journal Article
Mason, K. J., Jordan, K. P., Achana, F. A., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2022). P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.180

Abstract Background/Aims There is some evidence of an increased risk of cardiovascular disease in patients with painful musculoskeletal conditions, but it is unclear if musculoskeletal pain also worsens its prognosis. The aim was to determine whethe... Read More about P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study.

P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.182

Abstract Background/Aims The substantial personal and socioeconomic costs associated with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) make understanding their epidemiology crucial. The Clinical Practice Re... Read More about P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data.

New horizons in evidence-based care for older people: individual participant data meta-analysis (2022)
Journal Article
Clegg, A., Bandeen-Roche, K., Farrin, A., Forster, A., Gill, T., Gladman, J., …Witham, M. (2022). New horizons in evidence-based care for older people: individual participant data meta-analysis. Age and ageing, 51(4), https://doi.org/10.1093/ageing/afac090

Evidence-based decisions on clinical and cost-effectiveness of interventions are ideally informed by meta-analyses of intervention trial data. However, when undertaken, such meta-analyses in ageing research have typically been conducted using standar... Read More about New horizons in evidence-based care for older people: individual participant data meta-analysis.

Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019 (2022)
Journal Article
Mamas. (2022). Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcac016

Aims: We report disease-specific cardiovascular causes of mortality among cancer patients in the USA between 1999 and 2019, considering temporal trends by age, sex, and cancer site. Methods and results: We used the Multiple Cause of Death databas... Read More about Temporal trends in disease-specific causes of cardiovascular mortality amongst patients with cancer in the USA between 1999 and 2019.

Financial Incentives for Transcatheter Aortic Valve Implantation in Ontario, Canada: A Cost-Utility Analysis (2022)
Journal Article
Peel, J. K., Miranda, R. N., Naimark, D., Woodward, G., Mamas, M. A., Madan, M., & Wijeysundera, H. C. (2022). Financial Incentives for Transcatheter Aortic Valve Implantation in Ontario, Canada: A Cost-Utility Analysis. Journal of the American Heart Association, 11(8), Article ARTN e025085. https://doi.org/10.1161/jaha.121.025085

Background Transcatheter aortic valve implantation (TAVI) is a minimally invasive therapy for patients with severe aortic stenosis, which has become standard of care. The objective of this study was to determine the maximum cost-effective investment... Read More about Financial Incentives for Transcatheter Aortic Valve Implantation in Ontario, Canada: A Cost-Utility Analysis.

Overall Effects and Moderators of Rehabilitation in Patients With Wrist Fracture: A Systematic Review. (2022)
Journal Article
Pradhan, S., Chiu, S., Burton, C., Forsyth, J., Corp, N., Paskins, Z., …Babatunde, O. (2022). Overall Effects and Moderators of Rehabilitation in Patients With Wrist Fracture: A Systematic Review. Physical Therapy, 102(6), https://doi.org/10.1093/ptj/pzac032

OBJECTIVE: Wrist fractures constitute the most frequently occurring upper limb fracture. Many patients report persistent pain and functional limitations up to 18 months following wrist fracture. Identifying which patients are likely to gain the great... Read More about Overall Effects and Moderators of Rehabilitation in Patients With Wrist Fracture: A Systematic Review..

Feasibility study of student telehealth interviews (2022)
Journal Article
Zaccariah, Z. R., Irvine, A. W., & Lefroy, J. E. (2022). Feasibility study of student telehealth interviews. Clinical Teacher, 19(4), 308-315. https://doi.org/10.1111/tct.13490

Background The COVID-19 pandemic has led to medical students being taught remote clinical communication modalities (telephone and video). Junior students have not generally been included in this and have had less patient contact than previously. Thi... Read More about Feasibility study of student telehealth interviews.

Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review. (2022)
Journal Article
(2022). Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review. BMC medical research methodology, 101 - ?. https://doi.org/10.1186/s12874-022-01577-x

BACKGROUND: Describe and evaluate the methodological conduct of prognostic prediction models developed using machine learning methods in oncology. METHODS: We conducted a systematic review in MEDLINE and Embase between 01/01/2019 and 05/09/2019,... Read More about Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review..

Osteoarthritis Flares. (2022)
Journal Article
Thomas, M., Guillemin, F., & Neogi, T. (2022). Osteoarthritis Flares. Clinics in Geriatric Medicine, 38(2), 239 - 257. https://doi.org/10.1016/j.cger.2021.11.001

The phenomenon of flares is a common feature in the daily life of people with osteoarthritis (OA). Characterized by episodes of sudden-onset increases in signs and symptoms, their impact can often be distressing and disabling. Despite their potential... Read More about Osteoarthritis Flares..