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All Outputs (553)

Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia (2022)
Journal Article
Farooq, S., Hattle, M., Dazzan, P., Kingstone, T., Ajnakina, O., Shiers, D., …Van Der Windt, D. (in press). Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia. BMJ Open, 12(4), https://doi.org/10.1136/bmjopen-2021-056420

ABSTRACTIntroductionTreatment Resistant Schizophrenia (TRS) is associated with significant impairment of functioning and high treatment costs. Identification of patients at high risk of TRS at their initial diagnosis may significantly improve clinica... Read More about Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia.

The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial (2022)
Journal Article
Burton, C., Rathod-Mistry, T., Blackburn, S., Blagojevic-Bucknall, M., Bucknall, M., Chesterton, L., …Roddy, E. (2023). The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial. Rheumatology, 62(2), 546–554. https://doi.org/10.1093/rheumatology/keac219

Objectives This follow-up study of the INSTinCTS (INjection vs SplinTing in Carpal Tunnel Syndrome) trial compared the effects of corticosteroid injection (CSI) and night splinting (NS) for the initial management of mild-to-moderate carpal tunnel sy... Read More about The effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of a randomized trial.

Age stratified sex‐related differences in incidence, management, and outcomes of cardiogenic shock (2022)
Journal Article
Mamas, M. A., Osman, M., Syed, M., Kheiri, B., Bianco, C., Kalra, A., …Balla, S. (2022). Age stratified sex‐related differences in incidence, management, and outcomes of cardiogenic shock. Catheterization and Cardiovascular Interventions, 99(7), 1984-1995. https://doi.org/10.1002/ccd.30177

BACKGROUND: There is a lack of data on age-stratified sex differences in the incidence, treatment, and outcomes of cardiogenic shock (CS). We sought to study these differences from a contemporary database. METHODS: Patients admitted with CS (2004-201... Read More about Age stratified sex‐related differences in incidence, management, and outcomes of cardiogenic shock.

Evidence for overuse of cardiovascular healthcare services in high-income countries: protocol for a systematic review and meta-analysis. (2022)
Journal Article
Mamas. (2022). Evidence for overuse of cardiovascular healthcare services in high-income countries: protocol for a systematic review and meta-analysis. BMJ Open, e053920 - ?. https://doi.org/10.1136/bmjopen-2021-053920

INTRODUCTION: Overuse of cardiovascular healthcare services, defined as the provision of low-value (ineffective, harmful, cost-ineffective) tests, medications and procedures, may be common and associated with increased patient harm and health system... Read More about Evidence for overuse of cardiovascular healthcare services in high-income countries: protocol for a systematic review and meta-analysis..

Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries. (2022)
Journal Article
Zhang, W., Runhaar, J., Dell'Isola, A., Turkiewicz, A., Swain, S., Kamps, A., …Bierma-Zeinstra, S. (2022). Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries. BMJ Open, e052816 - ?. https://doi.org/10.1136/bmjopen-2021-052816

INTRODUCTION: Osteoarthritis (OA) is one of the leading chronic conditions in the older population. People with OA are more likely to have one or more other chronic conditions than those without. However, the temporal associations, clusters of the co... Read More about Comorbidities in osteoarthritis (ComOA): a combined cross-sectional, case-control and cohort study using large electronic health records in four European countries..

Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure (2022)
Journal Article
Chen, K., Li, C., Cornelius, V., Yu, D., Wang, Q., Shi, R., …Jiang, Z. (2022). Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure. JACC: Heart Failure, 10(6), 369-379. https://doi.org/10.1016/j.jchf.2022.01.010

BACKGROUND Blood pressure (BP) is a continuous and dynamic measure. However, standard BP control metrics may not reflect the variability in BP over time. OBJECTIVES This study assessed the prognostic value of time in BP target range among hypertensiv... Read More about Prognostic Value of Time in Blood Pressure Target Range Among Patients With Heart Failure.

Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial (2022)
Journal Article
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Hennings, S., …Mallen, C. D. (2022). Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial. BMJ, 377, Article ARTN e068446. https://doi.org/10.1136/bmj-2021-068446

Objectives: to compare the clinical effectiveness of best current treatment (BCT) plus single ultrasound-guided intra-articular hip injection (USGI) of 40mg triamcinolone acetonide and 4ml 1% lidocaine hydrochloride [BCT+US-Triamcinolone-Lidocaine] w... Read More about Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.

A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature (2022)
Journal Article
Darlington, D., Mayer, J., Panchal, G., Zachariah, D., Phan, T., Mallen, C., …Walker, V. (2022). A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature. Hearts, https://doi.org/10.3390/hearts3020007

Implantable loop recorders (ILR) are devices that are implanted subcutaneously on the chest, which enables the continuous monitoring of arrhythmias for up to three years. These devices have an important role in helping to make a diagnosis and support... Read More about A Review of the Wide Range of Indications and Uses of Implantable Loop Recorders: A Review of the Literature.

UK clinical guideline for the prevention and treatment of osteoporosis (2022)
Journal Article
Paskins. (2022). UK clinical guideline for the prevention and treatment of osteoporosis. Archives of Osteoporosis, 17, Article 58. https://doi.org/10.1007/s11657-022-01061-5

The National Osteoporosis Guideline Group (NOGG) has revised the UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. Accredited by NICE, thi... Read More about UK clinical guideline for the prevention and treatment of osteoporosis.

A Comparision of Node Detection Algorithms Over Wireless Sensor Network (2022)
Journal Article
Mahdi, H., Alwan, M., Al-Bander, B., & Zuhair, A. (2022). A Comparision of Node Detection Algorithms Over Wireless Sensor Network. International Journal of Interactive Mobile Technologies, 16(7), 38 - 53. https://doi.org/10.3991/ijim.v16i07.24609

MANET is standing for Network as Mobile Ad-hoc which is a self-directed mobile handlers group which communicates over relatively bandwidth constrained wireless channels. Many services with different classes of Quality of Services (QoS) could be provi... Read More about A Comparision of Node Detection Algorithms Over Wireless Sensor Network.

A Scoping Review: Mapping the Evidence for Undergraduate Concussion Education and Proposing the Content for Medical Student Concussion Teaching. (2022)
Journal Article
Gardner, N., & Heron, N. (2022). A Scoping Review: Mapping the Evidence for Undergraduate Concussion Education and Proposing the Content for Medical Student Concussion Teaching. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph19074328

INTRODUCTION: Concussion is a common yet complex condition, with each new case requiring assessment by a medical doctor. Recent research has shown that doctors working in the UK have significant knowledge deficits regarding concussion diagnosis and m... Read More about A Scoping Review: Mapping the Evidence for Undergraduate Concussion Education and Proposing the Content for Medical Student Concussion Teaching..

Clinician views on optimism and empathy in primary care consultations: a qualitative interview study (2022)
Journal Article
Hughes, S., Vennik, J., Smith, K., Bostock, J., Howick, J., Mallen, C., …Everitt, H. (2022). Clinician views on optimism and empathy in primary care consultations: a qualitative interview study. British Journal of General Practice Open (BJGP Open), 6(3), Article 0221. https://doi.org/10.3399/BJGPO.2021.0221

Background: Practitioner expressions of optimism and empathy may improve treatment engagement, adherence, and patient satisfaction but are not delivered consistently amid the challenges of everyday clinical practice. Aim: To explore primary care p... Read More about Clinician views on optimism and empathy in primary care consultations: a qualitative interview study.

Outcomes of rotational atherectomy followed by cutting balloon versus plain balloon before drug‐eluting stent implantation for calcified coronary lesions: A meta‐analysis (2022)
Journal Article
Mamas, M. A., Patel, N., Bandyopadhyay, D., Agarwal, G., Chakraborty, S., Kumar, A., …Naidu, S. S. (2022). Outcomes of rotational atherectomy followed by cutting balloon versus plain balloon before drug‐eluting stent implantation for calcified coronary lesions: A meta‐analysis. Catheterization and Cardiovascular Interventions, 99(6), 1741-1749. https://doi.org/10.1002/ccd.30159

AbstractObjectiveThe aim of this study is to compare outcomes of rotational atherectomy and cutting balloon (RACB) versus rotational atherectomy and plain balloon (RAPB) before drug‐eluting stent (DES) implantation in calcified coronary lesions.Metho... Read More about Outcomes of rotational atherectomy followed by cutting balloon versus plain balloon before drug‐eluting stent implantation for calcified coronary lesions: A meta‐analysis.

COMPARATIVE ANALYSIS OF PERCUTANEOUS REVASCULARIZATION PRACTICE IN THE UNITED STATES AND THE UNITED KINGDOM: INSIGHTS FROM THE BMC2 AND BCIS DATABASES (2022)
Presentation / Conference
Mamas. (2022, April). COMPARATIVE ANALYSIS OF PERCUTANEOUS REVASCULARIZATION PRACTICE IN THE UNITED STATES AND THE UNITED KINGDOM: INSIGHTS FROM THE BMC2 AND BCIS DATABASES. Presented at ACC 22, Washington DC, USA

Background: We compared clinical practice patterns, procedural outcomes, and trends in percutaneous coronary intervention (PCI) utilization using a state-wide PCI registry in the United States and a national registry from the United Kingdom (UK).... Read More about COMPARATIVE ANALYSIS OF PERCUTANEOUS REVASCULARIZATION PRACTICE IN THE UNITED STATES AND THE UNITED KINGDOM: INSIGHTS FROM THE BMC2 AND BCIS DATABASES.

Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article
Paskins, Z., Bullock, L., Manning, F., Bishop, S., Campbell, P., Cottrell, E., …Ryan, S. (2022). Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice. BMC Musculoskeletal Disorders, 23, Article 312. https://doi.org/10.1186/s12891-022-05273-1

Background Guidance for choosing face-to-face vs remote consultations (RCs) encourages clinicians to consider patient preferences, however, little is known about acceptability of, and preferences for RCs, particularly amongst patients with musculoske... Read More about Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.