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British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., …Williams, E. (2022). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), e48-e88. https://doi.org/10.1093/rheumatology/keac551

Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. (2022)
Journal Article
Elbadawi, A., Sedhom, R., Gad, M., Hamed, M., Elwagdy, A., Barakat, A. F., …Jneid, H. (2022). Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials. European Journal of Internal Medicine, 105, 38 - 45. https://doi.org/10.1016/j.ejim.2022.07.015

BACKGROUND: Randomized controlled trials (RCTs) investigating the optimal screening strategy for atrial fibrillation (AF) have yielded conflicting results. OBJECTIVE: To examine the comparative efficacy of different AF screening strategies in old... Read More about Screening for atrial fibrillation in the elderly: A network meta-analysis of randomized trials..

Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme (2022)
Journal Article
Philp, F., Faux-Nightingale, A., Bateman, J., Clark, H., Johnson, O., Klaire, V., …M Singh, B. (2022). Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme. BMJ Open, 12(11), Article e065709. https://doi.org/10.1136/bmjopen-2022-065709

OBJECTIVES: The association between impaired digital provision, access and health outcomes has not been systematically studied. The Wolverhampton Digital ENablement programme (WODEN) is a multiagency collaborative approach to determine and address di... Read More about Observational cross-sectional study of the association of poor broadband provision with demographic and health outcomes: the Wolverhampton Digital ENablement (WODEN) programme.

Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations (2022)
Journal Article
Campanholo, C. B., Maharaj, A. B., Corp, N., Bell, S., Costa, L., de Vlam, K., …Ogdie, A. (2022). Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations. The Journal of Rheumatology, 50(3), 426 - 432. https://doi.org/10.3899/jrheum.220310

Objective: The 2021 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations provide an evidence-based guide for selecting therapy based on the individual’s disease features. Beyond the disease feature... Read More about Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations.

Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry) (2022)
Journal Article
Mamas. (2022). Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry). American Journal of Cardiology, 1 - 7. https://doi.org/10.1016/j.amjcard.2022.07.039

QRS duration (QRSd) is ill-defined and under-researched as a prognosticator in patients with non–ST-segment myocardial infarction (NSTEMI). We analyzed 240,866 adult (=18 years) hospitalizations with non–ST-segment elevation myocardial infarction usi... Read More about Impact of QRS Duration on Non–ST-Segment Elevation Myocardial Infarction (from a National Registry).

Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes (2022)
Journal Article
Mamas. (2022). Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes. Diabetes Care, 2737-2745. https://doi.org/10.2337/dc22-0894

OBJECTIVE Heart failure (HF) often develops in patients with diabetes and is recognized for its role in increased cardiovascular morbidity and mortality in this population. Most existing models predict risk in patients with prevalent rather than i... Read More about Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients with Incident Diabetes.

Systematic reviews of the management of premenstrual disorder through the elimination of ovulation (2022)
Thesis
Naheed, B. (2022). Systematic reviews of the management of premenstrual disorder through the elimination of ovulation. (Thesis). Keele University

Premenstrual syndrome (PMS) is a distressing psychological and somatic disorder of unidentified aetiology occurring during the luteal phase of the menstrual cycle. This thesis includes systematic reviews of the published literature on the therapeutic... Read More about Systematic reviews of the management of premenstrual disorder through the elimination of ovulation.

A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia (2022)
Thesis
Chacko, S. M. (2022). A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia. (Thesis). Keele University

Introduction: Acute myocardial ischaemia and the transition from reversible to irreversible myocardial injury are associated with abnormal metabolic patterns. Advances in metabolomics have extended our capabilities to define these metabolic perturbat... Read More about A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia.

Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. (2022)
Journal Article
Nolan. (2022). Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis. Frontiers in Cardiovascular Medicine, 1022415 - ?. https://doi.org/10.3389/fcvm.2022.1022415

BACKGROUND: Old age and the presence of aortic stenosis are associated with the unfolding of the intrathoracic aorta. This may result in increased difficulties navigating catheters from the right compared to the left radial approach. OBJECTIVE: To in... Read More about Left vs. right radial approach for coronary catheterization: Relation to age and severe aortic stenosis..

Developing tools for inter-site transport of brain tissue models in tissue engineering research (2022)
Thesis
Kabiri, B. (2022). Developing tools for inter-site transport of brain tissue models in tissue engineering research. (Thesis). Keele University

Penetrating traumatic brain injury (pTBI) remains one of the leading causes of death in the younger population in the UK, as no clinical regenerative therapies are available. Experimental therapies currently being screened for efficacy are wide rangi... Read More about Developing tools for inter-site transport of brain tissue models in tissue engineering research.

Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group (2022)
Journal Article
Holden, M., Metcalf, B., Lawford, B., Hinman, R., Boyd, M., Button, K., …Bennell, K. (2023). Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group. Osteoarthritis and Cartilage, 31(3), 386-396. https://doi.org/10.1016/j.joca.2022.10.009

Objective To develop evidence-informed recommendations to support the delivery of best practice therapeutic exercise for people with knee and/or hip osteoarthritis (OA). Design A multi-stage, evidence-informed, international multi-disciplinary c... Read More about Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group.

Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. (2022)
Journal Article
Mamas. (2022). Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States. https://doi.org/10.1080/14779072.2022.2138858

BACKGROUND: A significant proportion of the world's population lives with physical disability (PD) requiring healthcare services. Risk factors for cardiovascular disease (CVD) such as hypertension and diabetes are more prevalent among patients with P... Read More about Outcomes of acute myocardial infarction in patients with preexisting physical disability: a report in the United States..

Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions (2022)
Journal Article
Bullock-Palmer, R. P., Bravo-Jaimes, K., Mamas, M. A., & Grines, C. L. (2022). Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions. European Cardiology Review, 17, https://doi.org/10.15420/ecr.2022.23

In the past few decades, the accelerated improvement in technology has allowed the development of new and effective coronary and structural heart disease interventions. There has been inequitable patient access to these advanced therapies and signifi... Read More about Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions.

Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies. (2022)
Journal Article
Kwok, C., Muntean, E., Mallen, C., & Borovac, J. (2022). Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies. Clinics and Practice, 832 - 844. https://doi.org/10.3390/clinpract12060088

There is considerable interest in data analytics because of its value in informing decisions in healthcare. Data variables can be derived from routinely collected records or from primary studies. The level of detail for individual variables in quanti... Read More about Data Collection Theory in Healthcare Research: The Minimum Dataset in Quantitative Studies..

Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. (2022)
Journal Article
Roddy, E. (2022). Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. Arthritis and Rheumatology, 75(5), 816-825. https://doi.org/10.1002/art.42393

OBJECTIVE: To determine whether a gout polygenic risk score (PRS) associates with age at gout onset and tophaceous disease in European (EUR), East Polynesian (EP), and West Polynesian (WP) men/women with gout. METHODS: A 19-variant gout PRS was p... Read More about Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout..

Stroke and TIA Survivors' Perceptions of the COVID-19 Vaccine and Influences on Its Uptake: Cross Sectional Survey. (2022)
Journal Article
Hughes, S., Turner, G., Heron, N., Crow, J., & Kontou, E. (2022). Stroke and TIA Survivors' Perceptions of the COVID-19 Vaccine and Influences on Its Uptake: Cross Sectional Survey. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph192113861

BACKGROUND: People who have experienced a stroke or transient ischaemic attack (TIA) have greater risks of complications from COVID-19. Therefore, vaccine uptake in this vulnerable population is important. To prevent vaccine hesitancy and maximise co... Read More about Stroke and TIA Survivors' Perceptions of the COVID-19 Vaccine and Influences on Its Uptake: Cross Sectional Survey..

Is vaccination against COVID-19 associated with psoriasis or eczema flare? Self-controlled case series analysis using data from the Clinical Practice Research Datalink (Aurum) (2022)
Journal Article
Adams, L., Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Van-Tam, J. S. N., …Abhishek, A. (2023). Is vaccination against COVID-19 associated with psoriasis or eczema flare? Self-controlled case series analysis using data from the Clinical Practice Research Datalink (Aurum). British Journal of Dermatology, 188(2), 297-299. https://doi.org/10.1093/bjd/ljac061

Patient and public involvement in implementation of evidence-based guidance for musculoskeletal conditions: a scoping review of current advances and gaps (2022)
Journal Article
Babatunde, O. O., Dawson, S., Brammar, J., Parton, L., Dziedzic, K., & Adebajo, A. O. (2022). Patient and public involvement in implementation of evidence-based guidance for musculoskeletal conditions: a scoping review of current advances and gaps. BMC Rheumatology, 6, Article 84. https://doi.org/10.1186/s41927-022-00310-x

Advances in musculoskeletal (MSK) research have been successfully curated into widely endorsed evidence-based recommendations and guidelines. However, there continues to exist significant variations in care and quality of care, and the global health... Read More about Patient and public involvement in implementation of evidence-based guidance for musculoskeletal conditions: a scoping review of current advances and gaps.

Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model. (2022)
Journal Article
Moledina, S. M., Kontopantelis, E., & Mamas, M. (2022). Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model. European Heart Journal, 4212 - ?. https://doi.org/10.1093/eurheartj/ehac477

This commentary refers to ‘Ethnicity-dependent performance of the Global Registry of Acute Coronary Events risk score for prediction of non-ST-segment elevation myocardial infarction in-hospital mortality: nationwide cohort study’, by S.M. Moledina e... Read More about Phenotypical differences in the characteristics of a population affects both the mortality and the performance of a risk-scoring model..

Intermediate care in caring for dementia, the point of view of general practitioners: A key informant survey across Europe. (2022)
Journal Article
Dibao-Dina, C., Oger, C., Foley, T., Torzsa, P., Lazic, V., Kreitmayer Peštiae, S., …Petrazzuoli, F. (2022). Intermediate care in caring for dementia, the point of view of general practitioners: A key informant survey across Europe. Frontiers in Medicine, https://doi.org/10.3389/fmed.2022.1016462

Background: Intermediate care is often defined as healthcare occurring somewhere between traditional primary (community) and secondary (hospital) care settings. High quality intermediate care is important in dementia, may prevent caregiver burnout an... Read More about Intermediate care in caring for dementia, the point of view of general practitioners: A key informant survey across Europe..