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All Outputs (623)

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer (2023)
Journal Article
Mamas, M. A., Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., …Petersen, S. E. (2023). Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer. Heart, heartjnl-2022-321888. https://doi.org/10.1136/heartjnl-2022-321888

Objectives: To evaluate incident cardiovascular outcomes and imaging phenotypes in UK Biobank participants with previous cancer. Methods: Cancer and cardiovascular disease (CVD) diagnoses were ascertained using health record linkage. Participants wit... Read More about Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer.

Design and evaluation of a new consolidation exercise for students studying cardiac physiology: a digital escape room. (2023)
Journal Article
Horn. (2023). Design and evaluation of a new consolidation exercise for students studying cardiac physiology: a digital escape room. Advances in physiology education, 47(1), 82 - 92. https://doi.org/10.1152/advan.00176.2022

The current student body will, by and large, seek online resources to supplement their learning. However, resources that are freely available online vary in accuracy and quality, and the vast majority rely on passive learning. Therefore, there is a n... Read More about Design and evaluation of a new consolidation exercise for students studying cardiac physiology: a digital escape room..

CKD-Associated Cardiovascular Mortality in the United States: Temporal Trends From 1999 to 2020. (2023)
Journal Article
Kobo, O., Abramov, D., Davies, S., Ahmed, S. B., Sun, L. Y., Mieres, J. H., …Mamas, M. A. (2023). CKD-Associated Cardiovascular Mortality in the United States: Temporal Trends From 1999 to 2020. KIDNEY MEDICINE, 5(3), Article 100597. https://doi.org/10.1016/j.xkme.2022.100597

RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular (CV) mortality, but there are limited data on temporal trends disaggregated by sex, race, and urban/rural status in this population. STUDY DESI... Read More about CKD-Associated Cardiovascular Mortality in the United States: Temporal Trends From 1999 to 2020..

Novel capsaicin cough endpoints effectively discriminate between healthy controls and patients with refractory chronic cough (2023)
Journal Article
Smith, J., Holt, K., & Belcher, J. (2023). Novel capsaicin cough endpoints effectively discriminate between healthy controls and patients with refractory chronic cough. Respiratory Medicine, 107142 - 107142. https://doi.org/10.1016/j.rmed.2023.107142

Rationale Chronic cough is a common problem, substantially affecting quality of life. Effective treatments and diagnostic clinical tools for refractory chronic cough are lacking which remains a diagnosis of exclusion. Objectives To investigate capsai... Read More about Novel capsaicin cough endpoints effectively discriminate between healthy controls and patients with refractory chronic cough.

Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. (2023)
Journal Article
Faux-Nightingale, A., Burton, C., Twohig, H., Bucknall, M., Carroll, W., Chew-Graham, C., …Welsh, V. (2023). Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol. British Journal of General Practice Open (BJGP Open), 7(2), Article BJGPO20220149. https://doi.org/10.3399/bjgpo.2022.0149

Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks. Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP)... Read More about Symptom patterns and life with post-acute COVID-19 in children aged 8-17: a mixed methods studyprotocol..

Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study (2023)
Journal Article
Mason, K. J., Jordan, K. P., Heron, N., Edwards, J. J., Bailey, J., Achana, F. A., …Marshall, M. (2023). Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study. Musculoskeletal Care, 21(3), 749-762. https://doi.org/10.1002/msc.1748

OBJECTIVE: Musculoskeletal painful conditions are a risk factor for cardiovascular disease (CVD), but less is known about whether musculoskeletal pain also worsens prognosis from CVD. The objective was to determine whether patients with musculoskelet... Read More about Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study.

Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents (2023)
Journal Article
Dunn, K., Montgomery, L. R., Andreucci, A., Kamper, S. J., van der Windt, D., Michaleff, Z. A., …Swain, M. S. (2023). Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents. Cochrane Database of Systematic Reviews, 2023(2), https://doi.org/10.1002/14651858.cd014773

Objectives This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: We aim to describe the overall prognosis (focusing on the pain course) and the negative impact(s) of acute and chronic musculoskeletal, widespread, an... Read More about Overall prognosis of acute and chronic musculoskeletal, widespread, and neuropathic pain in children and adolescents.

Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction (2023)
Journal Article
Sethupathi, P., Matetic, A., Bang, V., Myint, P. K., Rendon, I., Bagur, R., …Mamas, M. A. (2023). Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction. Cardiovascular Revascularization Medicine, 52, 16-22. https://doi.org/10.1016/j.carrev.2023.02.008

Background: Diabetes mellitus (DM) is an important risk factor for adverse outcomes following acute myocardial infarction (AMI), but large-scale studies investigating the differential impact of Type 1 DM (T1DM) and Type 2 DM (T2DM) on AMI outcomes ar... Read More about Association of Diabetes Mellitus and Its Types with In-Hospital Management and Outcomes of Patients with Acute Myocardial Infarction.

Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet? (2023)
Journal Article
Averbuch, T., Mamas, M. A., & Van Spall, H. G. C. (in press). Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?. Jama Network Open, 6(2), e230577. https://doi.org/10.1001/jamanetworkopen.2023.0577

People with breast cancer are at increased risk of cardiovascular disease, myocardial injury, and heart failure (HF) due to underlying risk factors, a proinflammatory milieu, and cancer therapy–related cardiovascular toxic effects (CTR-CVT).1 Of the... Read More about Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?.

Sex and country differences in gout: cross-country comparison between Sweden and the UK (2023)
Journal Article
Dehlin, M., Muller, S., Mallen, C., Landgren, A., Watson, L., Jacobsson, L., & Roddy, E. (2023). Sex and country differences in gout: cross-country comparison between Sweden and the UK. Scandinavian Journal of Rheumatology, 52(6), 673-682. https://doi.org/10.1080/03009742.2023.2177383

OBJECTIVE: Compare characteristics, sex differences, and management of gout in Sweden and the UK. METHOD: The results from two separate primary care gout surveys from Sweden and the UK were compared. Participants aged =18 years with gout were sent a... Read More about Sex and country differences in gout: cross-country comparison between Sweden and the UK.

The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation (2023)
Journal Article
Holland, D., Heald, A. H., Hanna, F. F., Stedman, M., Wu, P., Sim, J., …Fryer, A. A. (2023). The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation. Diabetes Therapy, 14, 691-707. https://doi.org/10.1007/s13300-023-01380-x

INTRODUCTION: Studies show that the COVID-19 pandemic disproportionately affected people with diabetes and those from disadvantaged backgrounds. During the first 6 months of the UK lockdown,?>?6.6 M glycated haemoglobin (HbA1c) tests were missed. We... Read More about The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation.

Disparities in the age at osteoarthritis diagnosis: an indicator for equity-focused prevention (2023)
Journal Article
Peat, G., Kiadaliri, A., & Yu, D. (2023). Disparities in the age at osteoarthritis diagnosis: an indicator for equity-focused prevention. Rheumatology, 62(8), e240-e241. https://doi.org/10.1093/rheumatology/kead080

Objectives: To investigate the association between vaccination against COVID-19 and inflammatory bowel disease (IBD) flare. Methods: Patients with IBD vaccinated against COVID-19 who consulted for disease flare between 01/12/2020 and 31/12/2021 were... Read More about Disparities in the age at osteoarthritis diagnosis: an indicator for equity-focused prevention.

Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis (2023)
Journal Article
Sedhom, R., Dang, A. T., Elwagdy, A., Megaly, M., Elgendy, I. Y., Zahr, F., …Mamas, M. (2023). Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis. Catheterization and Cardiovascular Interventions, 101(4), 817-827. https://doi.org/10.1002/ccd.30597

AbstractBackgroundStudies comparing plug‐based (i.e., MANTA) with suture‐based (i.e., ProStar XL and ProGlide) vascular closure devices (VCDs) for large‐bore access closure after transcatheter aortic valve replacement (TAVR) have yielded mixed result... Read More about Outcomes with plug-based versus suture-based vascular closure device after transfemoral transcatheter aortic valve replacement: A systematic review and meta-analysis.

A Scoping Review of Transgender Policies in the 15 Most Commonly Played UK Professional Sports (2023)
Journal Article
McLarnon, M., Thornton, J., Knudson, G., Jones, N., Glover, D., Murray, A., …Heron, N. (2023). A Scoping Review of Transgender Policies in the 15 Most Commonly Played UK Professional Sports. International Journal of Environmental Research and Public Health, 20(4), 3568. https://doi.org/10.3390/ijerph20043568

INTRODUCTION: There has been much debate recently on the participation of transgender and gender-diverse (TGD) athletes in sport, particularly in relation to fairness, safety and inclusion. The 2021 IOC Framework on Fairness, Inclusion and Non-discri... Read More about A Scoping Review of Transgender Policies in the 15 Most Commonly Played UK Professional Sports.

Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019 (2023)
Journal Article
Chong, B., Jayabaskaran, J., Kong, G., Huak Chan, Y., Han Chin, Y., Goh, R., …Chew, N. W. (2023). Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019. EClinicalMedicine, 57, 3164-3178. https://doi.org/10.1016/j.eclinm.2023.101850

Aims The effect of the COVID-19 pandemic on care and outcomes across non-COVID-19 cardiovascular (CV) diseases is unknown. A systematic review and meta-analysis was performed to quantify the effect and investigate for variation by CV disease, geogra... Read More about Trends and Predictions of Malnutrition and Obesity in 204 Countries and Territories: an analysis of the Global Burden of Disease Study 2019.

The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study. (2023)
Journal Article
Mughal, F., Chew-Graham, C., Babatunde, O., Saunders, B., Meki, A., & Dikomitis, L. (2023). The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study. Health Expectations, 26(3), 1180-1188. https://doi.org/10.1111/hex.13733

BACKGROUND: Self-harm in young people is a serious concern but a deeper understanding of the functions of self-harm in young people can tailor care and inform new clinical interventions to reduce repeat self-harm and suicide risk. General practitione... Read More about The functions of self-harm in young people and their perspectives about future general practitioner-led care: A qualitative study..

High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study. (2023)
Journal Article
Bromley. (2023). High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph20043470

Over 250 million infants in low and middle-income countries do not fulfill their neurodevelopment potential. In this study, we assessed the incidence and risk factors for neurodevelopmental delay (NDD) among children born following obstructed labor i... Read More about High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study..

Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study (2023)
Journal Article
Ashworth, J., Bajpai, R., Muller, S., Bailey, J., Helliwell, T., Harrisson, S., …Mallen, C. (2023). Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study. The Lancet Regional Health Europe, 27, Article ARTN 100579. https://doi.org/10.1016/j.lanepe.2022.100579

Background The UK government reclassified gabapentin and pregabalin as ‘controlled drugs’ from April 2019. This study aimed to describe the trends in gabapentinoid prescribing before and immediately after reclassification, in the UK Clinical Practic... Read More about Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study.