All Outputs (623)

Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis (2023)
Journal Article
Khan, S. U., Agarwal, S., Arshad, H. B., Akbar, U. A., Mamas, M. A., Arora, S., …Shah, A. R. (in press). Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis. BMJ, 383, e077848. https://doi.org/10.1136/bmj-2023-077848

Objective: To assess the absolute treatment effects of intravascular imaging guided versus angiography guided percutaneous coronary intervention in patients with coronary artery disease, considering their baseline risk. Design: Systematic review and... Read More about Intravascular imaging guided versus coronary angiography guided percutaneous coronary intervention: systematic review and meta-analysis.

Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis. (2023)
Journal Article
Gomes, L. A., Rodrigues, A. M., Windt, D., Pires, D., Afreixo, V., Canhão, H., & Cruz, E. B. (in press). Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis. Journal of Orthopaedic & Sports Physical Therapy, 1-39. https://doi.org/10.2519/jospt.2023.11865

To explore the effects of minimal intervention of patient education (MIPE) for reducing disability and pain intensity in patients with low back pain (LBP). Intervention systematic review with meta-analysis of randomized controlled trials. We sea... Read More about Minimal Intervention of Patient Education for Low Back Pain: A Systematic Review with Meta-Analysis..

Outcome data from 15 years of cystic fibrosis newborn screening in a large UK region (2023)
Journal Article
Driscoll, S. J., Heinz, K., Goddard, P., Desai, M., & Gilchrist, F. J. (in press). Outcome data from 15 years of cystic fibrosis newborn screening in a large UK region. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2023-325955

Background: The West Midlands Newborn Bloodspot Screening Laboratory is one of 16 in the UK and serves two tertiary paediatric cystic fibrosis (CF) centres (Staffordshire Children’s Hospital at Royal Stoke and Birmingham Children’s Hospital). CF newb... Read More about Outcome data from 15 years of cystic fibrosis newborn screening in a large UK region.

How do clinicians prescribe bridging glucocorticoids in people starting or escalating disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a service evaluation survey (2023)
Journal Article
Prior, J. A., Roddy, E., Solis-Trapala, I., Cornwall, N., Jinks, C., Abhishek, A., …Hider, S. (in press). How do clinicians prescribe bridging glucocorticoids in people starting or escalating disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a service evaluation survey. Rheumatology Advances in Practice, 7(3), Article rkad102. https://doi.org/10.1093/rap/rkad102

Aneurysmal bone cysts: A UK wide tumor center experience (2023)
Journal Article
Bavan, L., Eastley, N., Stevenson, J., Mifsud, M., Bayliss, L., Mahmoud, S., …Kothari, A. (in press). Aneurysmal bone cysts: A UK wide tumor center experience. Journal of Surgical Oncology, 129(3), 601-608. https://doi.org/10.1002/jso.27499

Background and Objectives This multicenter retrospective series of consecutive extra-spinal aneurysmal bone cysts aims to identify risk factors for treatment failure. Methods Aneurysmal bone cysts treated within seven collaborating centers with... Read More about Aneurysmal bone cysts: A UK wide tumor center experience.

Perceived Epidemic Impacts and Mental Symptom Trajectories in Adolescents Back to School After COVID-19 Restriction: A Longitudinal Latent Class Analysis (2023)
Journal Article
Rong, R., Xu, Q., Jordan, K. P., & Chen, Y. (2023). Perceived Epidemic Impacts and Mental Symptom Trajectories in Adolescents Back to School After COVID-19 Restriction: A Longitudinal Latent Class Analysis. Journal of Adolescent Health, 74(3), 487-495. https://doi.org/10.1016/j.jadohealth.2023.09.011

Purpose This study aimed to assess the impacts of COVID-19 epidemic on various life aspects and identify the trajectories of common mental symptoms among adolescents back to school after COVID-19 restriction. Furthermore, potential predictors associ... Read More about Perceived Epidemic Impacts and Mental Symptom Trajectories in Adolescents Back to School After COVID-19 Restriction: A Longitudinal Latent Class Analysis.

Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort. (2023)
Journal Article
Maher, G. M., Kenny, L. C., Navaratnam, K., Alfirevic, Z., Sheehan, D., Baker, P. N., …Khashan, A. S. (2023). Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort. HRB Open Research, 6(65), 1-19. https://doi.org/10.12688/hrbopenres.13812.2

BackgroundImproved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the assessment and refinement of innovative prototype preeclampsia risk assessment tes... Read More about Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort..

Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations] (2023)
Journal Article
Maher, G. M., Kenny, L. C., Navaratnam, K., Alfirevic, Z., Sheehan, D., Baker, P. N., …Khashan, A. S. (2023). Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations]. HRB Open Research, 6(65), https://doi.org/10.12688/hrbopenres.13812.1

Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the assessment and refinement of innovative prototype preeclampsia risk assessment t... Read More about Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 1; peer review: 1 approved with reservations].

Nonsurgical management of hallux valgus: findings of a randomised pilot and feasibility trial (2023)
Journal Article
Menz, H. B., Lim, P. Q. X., Hurn, S. E., Mickle, K. J., Buldt, A. K., Cotchett, M. P., …Munteanu, S. E. (in press). Nonsurgical management of hallux valgus: findings of a randomised pilot and feasibility trial. Journal of Foot and Ankle Research, 16(1), Article 78. https://doi.org/10.1186/s13047-023-00677-1

Background Hallux valgus is a common and disabling condition. This randomised pilot and feasibility trial aimed to determine the feasibility of conducting a parallel group randomised trial to evaluate the effectiveness of a nonsurgical intervention... Read More about Nonsurgical management of hallux valgus: findings of a randomised pilot and feasibility trial.

Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study. (2023)
Journal Article
Beaudart, C., Sharma, M., Clark, P., Fujiwara, S., Adachi, J. D., Messina, O. D., …Hiligsmann, M. (in press). Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study. Osteoporosis International, 35, 451–468. https://doi.org/10.1007/s00198-023-06955-9

The RICO study indicated that most patients would like to receive information regarding their fracture risk but that only a small majority have actually received it. Patients globally preferred a visual presentation of fracture risk and were interest... Read More about Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study..

A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina. (2023)
Journal Article
Rajkumar, C. A., Foley, M. J., Ahmed-Jushuf, F., Nowbar, A. N., Simader, F. A., Davies, J. R., …Al-Lamee, R. K. (in press). A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina. New England Journal of Medicine, https://doi.org/10.1056/NEJMoa2310610

Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving antianginal medication remains unknown. We conducted... Read More about A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina..

Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study (2023)
Journal Article
Mason, K. J., Alabas, O. A., Dand, N., Warren, R. B., Reynolds, N. J., Barker, J. N. W. N., …Warren, R. (2024). Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study. British Journal of Dermatology, 190(3), 441–444. https://doi.org/10.1093/bjd/ljad446

It is unknown why some psoriasis patients experience long-term effectiveness with their first biologic monotherapy. Our aim was to compare the baseline demographic, disease, genotypic, clinical and lifestyle characteristics of patients with psoriasis... Read More about Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study.

Machine learning models based on routinely sampled blood tests can predict the presence of malignancy amongst patients with suspected musculoskeletal malignancy (2023)
Journal Article
Bentick, K., Runevic, J., Akula, S., Kyriacou, T., Cool, P., & Andras, P. (2023). Machine learning models based on routinely sampled blood tests can predict the presence of malignancy amongst patients with suspected musculoskeletal malignancy. Methods, 220, 55-60. https://doi.org/10.1016/j.ymeth.2023.10.012

This study explores the possibility of using routinely taken blood tests in the diagnosis and triage of patients with suspected musculoskeletal malignancy. A retrospective study was performed on results of patients who had presented for assessment to... Read More about Machine learning models based on routinely sampled blood tests can predict the presence of malignancy amongst patients with suspected musculoskeletal malignancy.

Sex-based analysis of NSTEMI processes of care and outcomes by hospital: a nationwide cohort study (2023)
Journal Article
Moledina, S., Weight, N., Dafaalla, M., Chen, D., Rashid, M., Mohamed, M., …Mamas, M. (2023). Sex-based analysis of NSTEMI processes of care and outcomes by hospital: a nationwide cohort study. European Heart Journal, 44(Supplement_2), Article ehad655.3027. https://doi.org/10.1093/eurheartj/ehad655.3027

Background Contemporary studies have demonstrated that in non-ST-segment elevation myocardial infarction (NSTEMI), processes of care vary significantly according to biological sex. Little is known regarding variation in practice between geographical... Read More about Sex-based analysis of NSTEMI processes of care and outcomes by hospital: a nationwide cohort study.

Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among patients with cardiogenic shock (2023)
Journal Article
Mohamed, M., Kinnaird, T., Rab, T., Zaman, S., Banerjee, A., Sirker, A., …Mamas, M. (2023). Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among patients with cardiogenic shock. European Heart Journal, 44(Supplement_2), https://doi.org/10.1093/eurheartj/ehad655.2111

Background Intracoronary imaging (ICI), including intravascular ultrasound (IVUS) or optical coherence tomography (OCT), is known to correlate with a reduction in rates of cardiac death after percutaneous coronary intervention (PCI), driven by lower... Read More about Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among patients with cardiogenic shock.

Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists (2023)
Dataset
Jordan, K., Mason, K., Bailey, J., Protheroe, J., Mughal, F., Thomas, M., …Dunn, K. (2023). Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists. [Dataset]

SNOMED Clinical terminology and Clinical Practice Record Datalink (CPRD) AURUM dataset code lists from CAM-Pain programme 2023: The aim of the CAM-Pain programme is to improve the understanding, self-management, impact and healthcare of musculoske... Read More about Addressing Child and Adolescent Musculoskeletal Pain: the CAM-Pain Programme - Code Lists.

Risk of myocardial infarction following capecitabine treatment in patients with gastrointestinal cancer - a nationwide registry-based study (2023)
Journal Article
Shanmuganathan, J., Kragholm, K. H., Schou, M., Torp-Pedersen, C., Ostergaard Poulsen, L., Pareek, M., …Freeman, P. (2023). Risk of myocardial infarction following capecitabine treatment in patients with gastrointestinal cancer - a nationwide registry-based study. European Heart Journal, 44(Supplement_2), https://doi.org/10.1093/eurheartj/ehad655.1208

Background Myocardial infarction is a cardiac adverse event associated with fluoropyrimidines such as 5-fluorouracil and its orally available prodrug capecitabine. There are limited data on the incidence, risk, and prognosis of capecitabine associate... Read More about Risk of myocardial infarction following capecitabine treatment in patients with gastrointestinal cancer - a nationwide registry-based study.

Sex specific lifetime risk of incident cardiovascular events. Results from a large British population-based cohort study (2023)
Journal Article
Pana, T. A., Mamas, M. A., Wareham, N. J., Khaw, K. T., Dawson, D. K., & Myint, P. K. (2023). Sex specific lifetime risk of incident cardiovascular events. Results from a large British population-based cohort study. European Heart Journal, 44(Supplement_2), https://doi.org/10.1093/eurheartj/ehad655.2375

Background There are marked sex differences in cardiovascular (CV) disease, most characteristically with men having a higher risk of coronary heart disease and myocardial infarction (MI). The sex differences in the absolute lifetime risk of CV diseas... Read More about Sex specific lifetime risk of incident cardiovascular events. Results from a large British population-based cohort study.

Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among complex patient groups (2023)
Journal Article
Mohamed, M., Kinnaird, T., Wijeysundera, H. C., Johnson, T. W., Zaman, S., Moledina, S., & Mamas, M. (2023). Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among complex patient groups. European Heart Journal, 44(Supplement_2), https://doi.org/10.1093/eurheartj/ehad655.2112

Background Intracoronary imaging (ICI) has been previously shown to improve survival and clinical outcomes after percutaneous coronary intervention (PCI). However, whether this prognostic benefit is sustained across different indications/patient grou... Read More about Impact of intracoronary imaging-guided percutaneous coronary intervention on procedural outcomes among complex patient groups.

Cardiovascular events following vascular endothelial growth factor inhibitor therapy with sunitinib or pazopanib in patients with renal cell carcinoma - a nationwide registry-based follow-up study (2023)
Journal Article
Shanmuganathan, J., Schou, M., Haider Butt, J., Torp-Pedersen, C., Ostergaard Poulsen, L., Pareek, M., …Kragholm, K. H. (2023). Cardiovascular events following vascular endothelial growth factor inhibitor therapy with sunitinib or pazopanib in patients with renal cell carcinoma - a nationwide registry-based follow-up study. European Heart Journal, 44(Supplement_2), https://doi.org/10.1093/eurheartj/ehad655.2699

Background Use of oral vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) with focus on sunitinib and pazopanib approved for treatment of patients with renal cell carcinoma (RCC) may be associated with cardiovascula... Read More about Cardiovascular events following vascular endothelial growth factor inhibitor therapy with sunitinib or pazopanib in patients with renal cell carcinoma - a nationwide registry-based follow-up study.