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All Outputs (623)

Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study (2023)
Thesis
Ghosal, S. (2023). Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study. (Thesis). Keele University

Introduction The incidence of type 2 Diabetes mellitus (T2DM) is increasing and is a major public health burden. Obesity is one of the main modifiable risk factors for T2DM. However no UK studies have assessed the relationship of orlistat, a medica... Read More about Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study.

Implementing treat-to-target urate-lowering therapy during hospitalizations for gout flares (2023)
Journal Article
Russell, M. D., Ameyaw-Kyeremeh, L., Dell'Accio, F., Lapham, H., Head, N., Stovin, C., …Galloway, J. B. (in press). Implementing treat-to-target urate-lowering therapy during hospitalizations for gout flares. Rheumatology, https://doi.org/10.1093/rheumatology/kead574

Objectives To evaluate a strategy designed to optimize care and increase uptake of urate-lowering therapy (ULT) during hospitalizations for gout flares. Methods We conducted a prospective cohort study to evaluate a strategy that combined optimal... Read More about Implementing treat-to-target urate-lowering therapy during hospitalizations for gout flares.

Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth. (2023)
Journal Article
Benlefki, S., Younes, R., Challuau, D., Bernard-Marissal, N., Hilaire, C., Scamps, F., …Raoul, C. (in press). Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth. Cellular and Molecular Biology, 69(10), 1-8. https://doi.org/10.14715/cmb/2023.69.10.1

Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron diseases affecting adults and infants, respectively. ALS and SMA are both characterized by the selective degeneration of motoneurons. Although differ... Read More about Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth..

Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article
Hawarden, A., Holden, M. A., Paskins, Z., Roddy, E., Mallen, C. D., Liddle, J., …Jinks, C. (2023). Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study. Musculoskeletal Care, https://doi.org/10.1002/msc.1830

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic, or local anaesthetic alone, to advice and education among people with... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study.

Physiotherapist-led exercise versus usual care (waiting-list) control for patients awaiting rotator cuff repair surgery: A pilot randomised controlled trial (POWER). (2023)
Journal Article
Littlewood, C., Moffatt, M., Beckhelling, J., Davis, D., Burden, A., Pitt, L., …Foster, N. E. (in press). Physiotherapist-led exercise versus usual care (waiting-list) control for patients awaiting rotator cuff repair surgery: A pilot randomised controlled trial (POWER). Musculoskeletal Science and Practice, 68, Article 102874. https://doi.org/10.1016/j.msksp.2023.102874

Once a decision to undergo rotator cuff repair surgery is made, patients are placed on the waiting list. It can take weeks or months to receive surgery. There has been a call to move from waiting lists to 'preparation' lists to better prepare patient... Read More about Physiotherapist-led exercise versus usual care (waiting-list) control for patients awaiting rotator cuff repair surgery: A pilot randomised controlled trial (POWER)..

Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process. (2023)
Journal Article
Munce, S. E., Steele Gray, C., Pomeroy, B. C., Bayley, M., Kokorelias, K. M., Luong, D., …Kuluski, K. (in press). Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process. JMIR Research Protocols, 12, Article e50463. https://doi.org/10.2196/50463

Background: There is increasing evidence that co-design can lead to more engaging, acceptable, relevant, feasible, and even effective interventions. However, no guidance is provided on the specific designs and associated methods or methodologies inv... Read More about Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process..

Role of pan-national associations such as the European College of Sports and Exercise Physicians (ECOSEP) in advancing the specialty of sports and exercise medicine in the 21st century. (2023)
Journal Article
Scheer, V., Lohrer, H., Pakravan, A., Tsapralis, K., Valle, X., Ghrairi, M., …Bueno Padilla, J. M. (in press). Role of pan-national associations such as the European College of Sports and Exercise Physicians (ECOSEP) in advancing the specialty of sports and exercise medicine in the 21st century. BMJ Open Sport & Exercise Medicine, 9(4), Article e001703. https://doi.org/10.1136/bmjsem-2023-001703

Using video-based examiner score comparison and adjustment (VESCA) to compare the influence of examiners at different sites in a distributed objective structured clinical exam (OSCE) (2023)
Journal Article
Yeates, P., Maluf, A., Cope, N., McCray, G., McBain, S., Beardow, D., …McKinley, R. B. (2023). Using video-based examiner score comparison and adjustment (VESCA) to compare the influence of examiners at different sites in a distributed objective structured clinical exam (OSCE). BMC Medical Education, 23(1), Article 803. https://doi.org/10.1186/s12909-023-04774-4

Purpose: Ensuring equivalence of examiners’ judgements within distributed objective structured clinical exams (OSCEs) is key to both fairness and validity but is hampered by lack of cross-over in the performances which different groups of examiners o... Read More about Using video-based examiner score comparison and adjustment (VESCA) to compare the influence of examiners at different sites in a distributed objective structured clinical exam (OSCE).

Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study (2023)
Journal Article
Zghebi, S. S., Rutter, M. K., Sun, L. Y., Ullah, W., Rashid, M., Ashcroft, D. M., …Mamas, M. A. (in press). Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study. PloS one, 18(10), e0293314. https://doi.org/10.1371/journal.pone.0293314

Background: The prevalence of multimorbidity in patients with acute myocardial infarction (AMI) is increasing. It is unclear whether comorbidities cluster into distinct phenogroups and whether are associated with clinical trajectories. Methods: Surve... Read More about Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study.

Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis (2023)
Journal Article
Istanbuly, O., Belcher, J., Tabinor, M., Solis-Trapala, I., Lambie, M., & Davies, S. J. (in press). Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis. BMC Nephrology, 24(1), Article 312. https://doi.org/10.1186/s12882-023-03370-4

Background: Systemic inflammation, measured as circulating Interleukin-6 (IL-6) levels, is associated with cardiovascular and all-cause mortality in chronic kidney disease. However, this has not been convincingly demonstrated in a systematic review o... Read More about Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.

The INSIGHT project: reflections on the co-production of a quality recognition programme to showcase excellence in public involvement in health and care research (2023)
Journal Article
Blackburn, S., Hine, R., Fairbanks, S., Parkes, P., Murinas, D., Meakin, A., …Fryer, A. A. (2023). The INSIGHT project: reflections on the co-production of a quality recognition programme to showcase excellence in public involvement in health and care research. Research Involvement and Engagement, 9(1), 99. https://doi.org/10.1186/s40900-023-00508-4

Background: The quality of Patient and Public Involvement (PPI) in healthcare research varies considerably and is frequently tokenistic. We aimed to co-produce the Insight | Public Involvement Quality Recognition and Awards programme, based on the UK... Read More about The INSIGHT project: reflections on the co-production of a quality recognition programme to showcase excellence in public involvement in health and care research.

CSP2023: 185 THE LIVED EXPERIENCE OF PATIENTS WITH LATERAL ELBOW TENDINOPATHY – A QUALITATIVE STUDY FROM THE OPTIMISE PILOT & FEASIBILITY TRIAL (2023)
Presentation / Conference
Bateman, M., Saunders, B., Cooper, K., Littlewood, C., & Hill, J. (2023, October). CSP2023: 185 THE LIVED EXPERIENCE OF PATIENTS WITH LATERAL ELBOW TENDINOPATHY – A QUALITATIVE STUDY FROM THE OPTIMISE PILOT & FEASIBILITY TRIAL. Poster presented at Chartered Society of Physiotherapy (CSP) 2023 Annual Conference, London, England, UK

Complementary and alternative therapies for PTSD in refugees and asylum seekers: a systematic review (2023)
Journal Article
Paudyal, P., Less, E., & Cooper, M. (in press). Complementary and alternative therapies for PTSD in refugees and asylum seekers: a systematic review. European Journal of Public Health, 33(Supplement_2), ckad160.929. https://doi.org/10.1093/eurpub/ckad160.929

Background: Over 100 million people worldwide are displaced every year, including 26.3 million refugees and 4.5 million asylum seekers. Previous research has identified that up to 46% of asylum seekers and refugees (ASRs) use complementary and altern... Read More about Complementary and alternative therapies for PTSD in refugees and asylum seekers: a systematic review.

Impact of access to housing on mental health and coping amongst Ukrainian refugees in England (2023)
Journal Article
Seguin, M., Deinekhovska, T., Fokaf, O., Iemelianchuk, K., Poppleton, A., Roberts, B., …Egan, M. (2023). Impact of access to housing on mental health and coping amongst Ukrainian refugees in England. European Journal of Public Health, 33(Supplement_2), https://doi.org/10.1093/eurpub/ckad160.1633

Background Though the link between war-related trauma and poor mental health is well-established, less is known about stressors due to prolonged displacement, and how these relate to mental health. As the numbers of forcibly displaced persons rise wo... Read More about Impact of access to housing on mental health and coping amongst Ukrainian refugees in England.