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All Outputs (22)

Advances in Neurorestoratology—Current status and future developments (2023)
Book Chapter
Huang, H., Ramon-Cueto, A., El Masri, W., Moviglia, G. A., Saberi, H., Sharma, H. S., …Sarnowska, A. (2023). Advances in Neurorestoratology—Current status and future developments. . Elsevier. https://doi.org/10.1016/bs.irn.2023.04.003

Neurorestoratology constitutes a novel discipline aimed at the restoration of damaged neural structures and impaired neurological functions. This area of knowledge integrates and compiles all concepts and strategies dealing with the neurorestoration.... Read More about Advances in Neurorestoratology—Current status and future developments.

Chondrocyte Isolation and Expansion (2022)
Book Chapter
Harrison, P., Hopkins, T., Hulme, C., McCarthy, H., & Wright, K. Chondrocyte Isolation and Expansion. In Cartilage Tissue Engineering (9-19). Springer. https://doi.org/10.1007/978-1-0716-2839-3_2

Chondrocyte isolation requires a combination of enzymatic and mechanical digestion of cartilaginous tissues in order to release the chondrocytes. Extracted primary chondrocytes will then adhere to standard tissue culture plastics, typically in small... Read More about Chondrocyte Isolation and Expansion.

PCSK9 Inhibitors in Diabetic Dyslipidemia (2019)
Book Chapter
(2019). PCSK9 Inhibitors in Diabetic Dyslipidemia. In RSSDI Diabetes Update 2018 (374-378). https://doi.org/10.5005/jp/books/18092_77

The association between cardiovascular disease (CVD) risk and raised serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) has been demonstrated in epidemiology1 and intervention trials showing significant decreases in CVD foll... Read More about PCSK9 Inhibitors in Diabetic Dyslipidemia.

Use of fibrates in the Metabolic Syndrome and Diabetics: practical tips (2018)
Book Chapter
(2018). Use of fibrates in the Metabolic Syndrome and Diabetics: practical tips. In RSSDI Diabetes Update 2018 (356-361). https://doi.org/10.5005/jp/books/18092_73

Cardiovascular disease (CVD), a cause of mortality worldwide, accounted for 28% of United Kingdom deaths in 20121. Risk reduction is based on improving modifiable risk factors with lipid lowering therapy being particularly useful2. Because of the imp... Read More about Use of fibrates in the Metabolic Syndrome and Diabetics: practical tips.

Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging (2017)
Book Chapter
Bardsley, K., Deegan, A. J., El Haj, A., & Yang, Y. (2017). Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging. In Multi-Parametric Live Cell Microscopy of 3D Tissue Models (3-18). (1). Springer. https://doi.org/10.1007/978-3-319-67358-5_1

Mammalian cells grow within a complex three-dimensional (3D) microenvironment where multiple cells are organized and surrounded by extracellular matrix (ECM). The quantity and types of ECM components, alongside cell-to-cell and cell-to-matrix interac... Read More about Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging.

Magnetic Nanoparticle-Mediated Gene Delivery to Two- and Three-Dimensional Neural Stem Cell Cultures: Magnet-Assisted Transfection and Multifection Approaches to Enhance Outcomes. (2017)
Book Chapter
Pickard, M., Adams, C., & Chari, D. (2017). Magnetic Nanoparticle-Mediated Gene Delivery to Two- and Three-Dimensional Neural Stem Cell Cultures: Magnet-Assisted Transfection and Multifection Approaches to Enhance Outcomes. In Current Protocols in Stem Cell Biology (2D.19.1 - 2D.19.16). https://doi.org/10.1002/9780470151808

Neural stem cells (NSCs) have high translational potential in transplantation therapies for neural repair. Enhancement of their therapeutic capacity by genetic engineering is an important goal for regenerative neurology. Magnetic nanoparticles (MNPs)... Read More about Magnetic Nanoparticle-Mediated Gene Delivery to Two- and Three-Dimensional Neural Stem Cell Cultures: Magnet-Assisted Transfection and Multifection Approaches to Enhance Outcomes..

Biocompatibility of biodegradable medical polymers (2016)
Book Chapter
Ozdil, D., Wimpenny, I., Aydin, H., & Yang, Y. (2017). Biocompatibility of biodegradable medical polymers. . Elsevier. https://doi.org/10.1016/b978-0-08-100372-5.00013-1

Biomaterials have various applications in the medical field; whilst biodegradable biomaterials play an important role in regenerative medicine, tissue engineering and drug delivery. In addition to conversional biocompatibility, biodegradable material... Read More about Biocompatibility of biodegradable medical polymers.

Iron Oxides in the Human Brain (2016)
Book Chapter
Collingwood, J. F., & Telling, N. D. Iron Oxides in the Human Brain. In Iron Oxides: From Nature to Applications (143-176). Wiley. https://doi.org/10.1002/9783527691395.ch7

The presence and formation of iron oxide in the human brain are of interest to those engaged in understanding fundamental processes of biomineralization and of iron metabolism in neurobiology and neuropathology. There is evidence for the formation of... Read More about Iron Oxides in the Human Brain.

Image analysis and quantification of tissue scaffolds (2015)
Book Chapter
Yang, Y., & Wimpenny, I. (2015). Image analysis and quantification of tissue scaffolds. In Characterisation and Design of Tissue Scaffolds (201-223). Elsevier. https://doi.org/10.1016/b978-1-78242-087-3.00009-2

If you can measure something, then you can improve it. Measurement of the structural and functional parameters of tissue-engineering scaffolds is important in the context of better scaffold design, regulation of cellular activities, and the predictio... Read More about Image analysis and quantification of tissue scaffolds.

Potential use of hybrid iron oxide gold nanoparticles as drug carriers (2015)
Book Chapter
Curtis, A., & Hoskins, C. Potential use of hybrid iron oxide gold nanoparticles as drug carriers. In Nano Based Drug Delivery (535-546). IAPC Publishing (International Association of Physical Chemists). https://doi.org/10.5599/obp.8.21

Hybrid nanoparticles are composed of more than one material fused together to increase functionality. These often consist of polymers coated onto the surface of metallic nanoparticles to render them useful in biomedicine [1,2]. In this chapter the te... Read More about Potential use of hybrid iron oxide gold nanoparticles as drug carriers.

Introduction (2015)
Book Chapter
Moss, G. P. (2015). Introduction. In Novel Delivery Systems for Transdermal and Intradermal Drug Delivery (1-40). Wiley. https://doi.org/10.1002/9781118734506.ch1

This chapter describes the physiology and structure of the skin, emphasising and focusing on the skin's main barrier to permeation – the stratum corneum – and how its structure and nature, compared to other regions and layers of the skin, results in... Read More about Introduction.

A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function (2015)
Book Chapter
Mamas. (2015). A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function. In Medinfo 2015: Proceedings of the 15th World Congress on Health and Biomedical Informatics (696-700). https://doi.org/10.3233/978-1-61499-564-7-696

We demonstrate the use of electronic records and repeated measures of risk factors therein, to enable deeper understanding of the relationship between the full longitudinal trajectory of risk factors and outcomes. To illustrate, dynamic mixed effect... Read More about A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: illustrated with Kidney Function.

Public health (2014)
Book Chapter
White, S. (2014). Public health. In Pharmaceutical Practice. (5). Churchill Livingstone

Oocyte-Secreted Factors in Domestic Animals (2013)
Book Chapter
Thompson, J. G., Mottershead, D. G., & Gilchrist, R. B. Oocyte-Secreted Factors in Domestic Animals. . Wiley. https://doi.org/10.1002/9781118538074.ch4

Summary This chapter contains sections titled: Introduction Historical Background Localization and Specificity Structure and Genetic Diversity of Gdf9 and Bmp15 Signalling Mechanisms of Gdf9 and Bmp15 Roles of Oocyte-Secreted Factors Manipula... Read More about Oocyte-Secreted Factors in Domestic Animals.