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Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records (2014)
Journal Article
(2014). Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records. PloS one, e99825 - e99825. https://doi.org/10.1371/journal.pone.0099825

Lists of clinical codes are the foundation for research undertaken using electronic medical records (EMRs). If clinical code lists are not available, reviewers are unable to determine the validity of research, full study replication is impossible, re... Read More about Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records.

Statistical analysis plan for the Stroke Oxygen Study (SO2S): a multi-center randomized controlled trial to assess whether routine oxygen supplementation in the first 72 hours after a stroke improves long-term outcome. (2014)
Journal Article
Ives, N., Sim, J., Gray, R., Roffe, C., Nevatte, T., & Howman, A. (2014). Statistical analysis plan for the Stroke Oxygen Study (SO2S): a multi-center randomized controlled trial to assess whether routine oxygen supplementation in the first 72 hours after a stroke improves long-term outcome. Trials, 15, Article ARTN 229. https://doi.org/10.1186/1745-6215-15-229

BACKGROUND: The Stroke Oxygen Study (SO2S) is a multi-center randomized controlled trial of oxygen supplementation in patients with acute stroke. The main hypothesis for the trial is that fixed-dose oxygen treatment during the first 3 days after an a... Read More about Statistical analysis plan for the Stroke Oxygen Study (SO2S): a multi-center randomized controlled trial to assess whether routine oxygen supplementation in the first 72 hours after a stroke improves long-term outcome..

The SIFT and FALP techniques; applications to ionic and electronic reactions studies and their evolution to the SIFT-MS and FA-MS analytical methods (2014)
Journal Article
(2014). The SIFT and FALP techniques; applications to ionic and electronic reactions studies and their evolution to the SIFT-MS and FA-MS analytical methods. International Journal of Mass Spectrometry, 467 - 478. https://doi.org/10.1016/j.ijms.2014.05.016

Flow tube reactors coupled with quantitative mass spectrometry have made, and continue to make, major contributions to gas phase ion–molecule chemistry, to recombination and electron attachment studies and, most recently, to gas phase trace gas analy... Read More about The SIFT and FALP techniques; applications to ionic and electronic reactions studies and their evolution to the SIFT-MS and FA-MS analytical methods.

MicroRNA Profiles Discriminate among Colon Cancer Metastasis (2014)
Journal Article
Drusco, A., Nuovo, G. J., Zanesi, N., Di Leva, G., Pichiorri, F., Volinia, S., …Croce, C. M. (in press). MicroRNA Profiles Discriminate among Colon Cancer Metastasis. PloS one, 9(6), Article e96670. https://doi.org/10.1371/journal.pone.0096670

MicroRNAs are being exploited for diagnosis, prognosis and monitoring of cancer and other diseases. Their high tissue specificity and critical role in oncogenesis provide new biomarkers for the diagnosis and classification of cancer as well as predic... Read More about MicroRNA Profiles Discriminate among Colon Cancer Metastasis.

The influence of storage parameters on measurement of survival motor neuron (SMN) protein levels: Implications for pre-clinical studies and clinical trials for spinal muscular atrophy (2014)
Journal Article
Hunter, G., Roche, S. L., Somers, E., Fuller, H. R., & Gillingwater, T. H. (2014). The influence of storage parameters on measurement of survival motor neuron (SMN) protein levels: Implications for pre-clinical studies and clinical trials for spinal muscular atrophy. Neuromuscular Disorders, 24(11), 973-977. https://doi.org/10.1016/j.nmd.2014.05.013

Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide ß-amyloid (1-42). (2014)
Journal Article
Everett, & Telling. (2014). Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide ß-amyloid (1-42). https://doi.org/10.1098/rsif.2014.0165

For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide ß-amyloid (Aß). Despite many observations of this association, the relationship be... Read More about Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide ß-amyloid (1-42)..

Similarity of patient characteristics and outcomes in consecutive data collection on stroke admissions over one month compared to longer periods (2014)
Journal Article
(2014). Similarity of patient characteristics and outcomes in consecutive data collection on stroke admissions over one month compared to longer periods. BMC Research Notes, 342. https://doi.org/10.1186/1756-0500-7-342

Background The usefulness of time-limited consecutive data collection compared to continuous consecutive data collection in conditions which show seasonal variations is unclear. The objective of this study is to assess whether one month of admission... Read More about Similarity of patient characteristics and outcomes in consecutive data collection on stroke admissions over one month compared to longer periods.

Stable Isotope Dilution Gas Chromatography–Mass Spectrometry for Quantification of Thymoquinone in Black Cumin Seed Oil (2014)
Journal Article
Johnson-Ajinwo, O. R., & Li, W. (2014). Stable Isotope Dilution Gas Chromatography–Mass Spectrometry for Quantification of Thymoquinone in Black Cumin Seed Oil. Journal of Agricultural and Food Chemistry, 62(24), 5466-5471. https://doi.org/10.1021/jf500357x

Black cumin seed (Nigella sativa L.) is a widely used spice and herb, where thymoquinone (2-isopropyl-5-methyl-1,4-benzoquinone) is the major bioactive compound. Here, a stable isotope dilution (SID) gas chromatography–mass spectrometry (GC–MS) techn... Read More about Stable Isotope Dilution Gas Chromatography–Mass Spectrometry for Quantification of Thymoquinone in Black Cumin Seed Oil.

Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis (2014)
Journal Article
Kehoe, O., Cartwright, A., Askari, A., El Haj, A., & Middleton, J. (2014). Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis. Journal of Translational Medicine, 157 - ?. https://doi.org/10.1186/1479-5876-12-157

BACKGROUND: Rheumatoid arthritis (RA) is a debilitating and painful disease leading to increased morbidity and mortality and novel therapeutic approaches are needed. The purpose of this study was to elucidate if mesenchymal stem cells (MSCs) injected... Read More about Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis.

A Pedagogic Trinity – Exploring the Art, Craft and Science of Teaching (2014)
Journal Article
(2014). A Pedagogic Trinity – Exploring the Art, Craft and Science of Teaching

This article aims to convince the reader that teachers in the current Higher Education (HE) climate should be conducting educational research and offers a number of points exploring the potential benefits of regular teacher engagement with current pe... Read More about A Pedagogic Trinity – Exploring the Art, Craft and Science of Teaching.

Adults see vision to be more informative than it is (2014)
Journal Article
(2014). Adults see vision to be more informative than it is. https://doi.org/10.1080/17470218.2014.915331

Humans gain a wide range of knowledge through interacting with the environment. Each aspect of our perceptual experiences offers a unique source of information about the world—colours are seen, sounds heard and textures felt. Understanding how percep... Read More about Adults see vision to be more informative than it is.

Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy (2014)
Journal Article
Rutter, A. V., Siddique, M. R., Filik, J., Sandt, C., Dumas, P., Cinque, G., …Sulé-Suso, J. (2014). Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry Part A, 85(8), 688-697. https://doi.org/10.1002/cyto.a.22488

Over the last few years, significant scientific insight on the effects of chemotherapy drugs at cellular level using synchrotron-based FTIR (S-FTIR) microspectroscopy has been obtained. The work carried out so far has identified spectral differences... Read More about Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy.

Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron (2014)
Journal Article
Yousef, I., Seksek, O., Gil, S., Prezado, Y., Sulé-Suso, J., & Martínez-Rovira, I. (2014). Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron. Analyst, 141(7), 2238-2249. https://doi.org/10.1039/c5an02378e

Over the last few years, significant scientific insight on the effects of chemotherapy drugs at cellular level using synchrotron-based FTIR (S-FTIR) microspectroscopy has been obtained. The work carried out so far has identified spectral differences... Read More about Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron.

Improving alkynyl(aryl)iodonium salts: 2-anisyl as a superior aryl group (2014)
Journal Article
Moran, W., & Hamnett, D. (2014). Improving alkynyl(aryl)iodonium salts: 2-anisyl as a superior aryl group. Organic and Biomolecular Chemistry, 12(24), https://doi.org/10.1039/c4ob00556b

The majority of alkynyl(aryl)iodonium salts reported in the literature are derived from iodobenzene. This article describes the effects of varying this iodoarene building block on the synthesis, reactivity and stability of these salts. Two procedures... Read More about Improving alkynyl(aryl)iodonium salts: 2-anisyl as a superior aryl group.

Three-dimensional hypoxic culture of human mesenchymal stem cells encapsulated in a photocurable, biodegradable polymer hydrogel: A potential injectable cellular product for nucleus pulposus regeneration (2014)
Journal Article
Kumar, D., Gerges, I., Tamplenizza, M., Lenardi, C., Forsyth, N. R., & Liu, Y. (2014). Three-dimensional hypoxic culture of human mesenchymal stem cells encapsulated in a photocurable, biodegradable polymer hydrogel: A potential injectable cellular product for nucleus pulposus regeneration. Acta biomaterialia, 10(8), 3463-3474. https://doi.org/10.1016/j.actbio.2014.04.027

Nucleus pulposus (NP) tissue damage can induce detrimental mechanical stresses and strains on the intervertebral disc, leading to disc degeneration. This study demonstrates the potential of a novel, photo-curable, injectable, synthetic polymer hydrog... Read More about Three-dimensional hypoxic culture of human mesenchymal stem cells encapsulated in a photocurable, biodegradable polymer hydrogel: A potential injectable cellular product for nucleus pulposus regeneration.

Cells isolated from fat pad and synovial fluid. are they suitable for cartilage repair? (2014)
Journal Article
Garica, J., Mennan, C., Richardson, J., Wright, K., & Roberts, S. (2014). Cells isolated from fat pad and synovial fluid. are they suitable for cartilage repair?. Osteoarthritis and Cartilage, 22, S445. https://doi.org/10.1016/j.joca.2014.02.843

Purpose: Autologous Chondrocyte Implantation (ACI) is used as a cellular therapy for treating defects in articular cartilage. Successful ACI depends on high cell number and quality of the cells which varies between patients. Alternative cell sources... Read More about Cells isolated from fat pad and synovial fluid. are they suitable for cartilage repair?.

Sorption and biodegradation of organic micropollutants during river bank filtration: A laboratory column study (2014)
Journal Article
Bertelkamp, C., Reungoat, J., Cornelissen, E., Singhal, N., Reynisson, J., Cabo, A., …Verliefde, A. (2014). Sorption and biodegradation of organic micropollutants during river bank filtration: A laboratory column study. Water Research, 52, 231-241. https://doi.org/10.1016/j.watres.2013.10.068

This study investigated sorption and biodegradation behaviour of 14 organic micropollutants (OMP) in soil columns representative of the first metre (oxic conditions) of the river bank filtration (RBF) process. Breakthrough curves were modelled to dif... Read More about Sorption and biodegradation of organic micropollutants during river bank filtration: A laboratory column study.

The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry (2014)
Journal Article
Fuller, H. R., Hurtado, M. L., Wishart, T. M., & Gates, M. A. (2014). The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry. Proteome Science, 1-20. https://doi.org/10.1186/1477-5956-12-20

BACKGROUND: Idiopathic Parkinson's disease is marked by degeneration of dopamine neurons projecting from the substantia nigra to the striatum. Although proteins expressed by the target striatum can positively affect the viability and growth of dopami... Read More about The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry.