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All Outputs (18)

Development of a comprehensive musculoskeletal model of the shoulder and elbow (2011)
Journal Article
(2011). Development of a comprehensive musculoskeletal model of the shoulder and elbow. Medical and Biological Engineering and Computing, 1425 -1435. https://doi.org/10.1007/s11517-011-0839-7

The Delft Shoulder and Elbow Model (DSEM), a musculoskeletal model of the shoulder and elbow has been extensively developed since its introduction in 1994. Extensions cover both model structures and anatomical data focusing on the addition of an elbo... Read More about Development of a comprehensive musculoskeletal model of the shoulder and elbow.

X-ray magnetic circular dichroism study of the blocking process in nanostructured iron-iron oxide core-shell systems (2011)
Journal Article
Jiménez-Villacorta, F., Prieto, C., Huttel, Y., Telling, N. D., & van der Laan, G. X-ray magnetic circular dichroism study of the blocking process in nanostructured iron-iron oxide core-shell systems. Physical review B: Condensed matter and materials physics, 84(17), https://doi.org/10.1103/physrevb.84.172404

Experimental evidence for magnetothermal behavior in iron-iron oxide nanostructured systems has been obtained using x-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) at the Fe L 2 , 3 edges. The purpose of this s... Read More about X-ray magnetic circular dichroism study of the blocking process in nanostructured iron-iron oxide core-shell systems.

Control of nanoparticle size, reactivity and magnetic properties during the bioproduction of magnetite byGeobacter sulfurreducens (2011)
Journal Article
Byrne, J. M., Telling, N. D., Coker, V. S., Pattrick, R. A. D., van der Laan, G., Arenholz, E., …Lloyd, J. R. (2011). Control of nanoparticle size, reactivity and magnetic properties during the bioproduction of magnetite byGeobacter sulfurreducens. Nanotechnology, 22(45), Article 455709. https://doi.org/10.1088/0957-4484/22/45/455709

The bioproduction of nanoscale magnetite by Fe(III)-reducing bacteria offers a potentially tunable, environmentally benign route to magnetic nanoparticle synthesis. Here, we demonstrate that it is possible to control the size of magnetite nanoparticl... Read More about Control of nanoparticle size, reactivity and magnetic properties during the bioproduction of magnetite byGeobacter sulfurreducens.

The views of patients and the general public about expensive anti-cancer drugs in the NHS: a questionnaire-based study. (2011)
Journal Article
Solis-Trapala. (2011). The views of patients and the general public about expensive anti-cancer drugs in the NHS: a questionnaire-based study. JRSM Short Reports, 69. https://doi.org/10.1258/shorts.2011.011050

OBJECTIVES: To determine the views of patients and members of the public about who should pay for expensive new cancer drugs not recommended by the National Institute for Health and Clinical Excellence (NICE). DESIGN: A study-specific questionnaire w... Read More about The views of patients and the general public about expensive anti-cancer drugs in the NHS: a questionnaire-based study..

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis (2011)
Journal Article
(2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature, 214 -219. https://doi.org/10.1038/nature10251

Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disabi... Read More about Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Evidence for consistency of the glycation gap in diabetes (2011)
Journal Article
(2011). Evidence for consistency of the glycation gap in diabetes. Diabetes Care, 1712 -1716. https://doi.org/10.2337/dc10-1767

OBJECTIVE: Discordance between HbA(1c) and fructosamine estimations in the assessment of glycemia is often encountered. A number of mechanisms might explain such discordance, but whether it is consistent is uncertain. This study aims to coanalyze pai... Read More about Evidence for consistency of the glycation gap in diabetes.

A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae (2011)
Journal Article
(2011). A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryotic Cell, 1241 -1250. https://doi.org/10.1128/ec.05029-11

Potassium homeostasis is crucial for living cells. In the yeast Saccharomyces cerevisiae, the uptake of potassium is driven by the electrochemical gradient generated by the Pma1 H(+)-ATPase, and this process represents a major consumer of the gradien... Read More about A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae.

The SOS pilot study: a RCT of routine oxygen supplementation early after acute stroke--effect on recovery of neurological function at one week (2011)
Journal Article
(2011). The SOS pilot study: a RCT of routine oxygen supplementation early after acute stroke--effect on recovery of neurological function at one week. PloS one, e19113 - ?. https://doi.org/10.1371/journal.pone.0019113

Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no significant benefit at 7 and 12 months. Th... Read More about The SOS pilot study: a RCT of routine oxygen supplementation early after acute stroke--effect on recovery of neurological function at one week.

Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets (2011)
Journal Article
Mamas. (2011). Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets. Bioinformatics, 1108 -1112. https://doi.org/10.1093/bioinformatics/btr079

MOTIVATION: The study of metabolites (metabolomics) is increasingly being applied to investigate microbial, plant, environmental and mammalian systems. One of the limiting factors is that of chemically identifying metabolites from mass spectrometric... Read More about Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets.

Phase-resolved x-ray ferromagnetic resonance measurements in fluorescence yield (2011)
Journal Article
Marcham, M. K., Keatley, P. S., Neudert, A., Hicken, R. J., Cavill, S. A., Shelford, L. R., …Arenholz, E. (2011). Phase-resolved x-ray ferromagnetic resonance measurements in fluorescence yield. Journal of Applied Physics, 109(7), https://doi.org/10.1063/1.3567143

Phase-resolved x-ray ferromagnetic resonance (XFMR) has been measured in fluorescence yield, extending the application of XFMR to opaque samples on opaque substrates. Magnetization dynamics were excited in a Co50Fe50(0.7)/Ni90Fe10(5) bilayer by means... Read More about Phase-resolved x-ray ferromagnetic resonance measurements in fluorescence yield.

A variational Bayesian approach for the robust analysis of the cortical silent period from EMG recordings of brain stroke patients (2011)
Journal Article
(2011). A variational Bayesian approach for the robust analysis of the cortical silent period from EMG recordings of brain stroke patients. Neurocomputing, 1301 -1314. https://doi.org/10.1016/j.neucom.2010.12.006

Transcranial magnetic stimulation (TMS) is a powerful tool for the calculation of parameters related to the intracortical excitability and inhibition of the motor cortex. The cortical silent period (CSP) is one such parameter that corresponds to the... Read More about A variational Bayesian approach for the robust analysis of the cortical silent period from EMG recordings of brain stroke patients.

Comparative cardiovascular effects of the thiazolidinediones: Systematic review and meta-analysis of Observational Studies (2011)
Journal Article
(2011). Comparative cardiovascular effects of the thiazolidinediones: Systematic review and meta-analysis of Observational Studies. BMJ, https://doi.org/10.1136/bmj.d1309

Objective To determine the comparative effects of the thiazolidinediones (rosiglitazone and pioglitazone) on myocardial infarction, congestive heart failure, and mortality in patients with type 2 diabetes. Design Systematic review and meta-analysi... Read More about Comparative cardiovascular effects of the thiazolidinediones: Systematic review and meta-analysis of Observational Studies.

Bone Marrow for the Treatment of Spinal Cord Injury: Mechanisms and Clinical Application. (2011)
Journal Article
(2011). Bone Marrow for the Treatment of Spinal Cord Injury: Mechanisms and Clinical Application. STEM CELLS, 169-178. https://doi.org/10.1002/stem.570

Transplantation of bone marrow stem cells into spinal cord lesions enhances axonal regeneration and promotes functional recovery in animal studies. There are two types of adult bone marrow stem cell; haematopoietic stem cells (HSCs) and mesenchymal s... Read More about Bone Marrow for the Treatment of Spinal Cord Injury: Mechanisms and Clinical Application..

Anisotropic x-ray magnetic linear dichroism and spectromicroscopy of interfacial Co/NiO(001) (2011)
Journal Article
van der Laan, G., Telling, N. D., Potenza, A., Dhesi, S. S., & Arenholz, E. Anisotropic x-ray magnetic linear dichroism and spectromicroscopy of interfacial Co/NiO(001). Physical review B: Condensed matter and materials physics, 83(6), Article 064409. https://doi.org/10.1103/physrevb.83.064409

Photoemission electron microscopy (PEEM) with linearly polarized x rays is used to determine the orientation of antiferromagnetic domains by monitoring the relative peak intensities at the 3 d transition metal L 2 absorption edge. In such a... Read More about Anisotropic x-ray magnetic linear dichroism and spectromicroscopy of interfacial Co/NiO(001).

Raltegravir is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir (2011)
Journal Article
(2011). Raltegravir is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir. Antimicrobial Agents and Chemotherapy, 879-887. https://doi.org/10.1128/AAC.00623-10

The identification of transporters of the HIV integrase inhibitor raltegravir could be a factor in an understanding of the pharmacokinetic-pharmacodynamic relationship and reported drug interactions of raltegravir. Here we determined whether raltegr... Read More about Raltegravir is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir.