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Highest oxygen consumption prediction: introducing variable theoretical proportional factors for different sports (2024)
Journal Article
Lorenzo-Capellá, I., Ramos-Álvarez, J. J., Jiménez-Herranz, M. E., Maffulli, N., de Borba, E. F., Iuliano, E., Calderón-Montero, F. J., Ardigò, L. P., Russo, L., & Padulo, J. (in press). Highest oxygen consumption prediction: introducing variable theoretical proportional factors for different sports. European Journal of Applied Physiology, https://doi.org/10.1007/s00421-024-05625-w

Purpose
The use of a fixed theoretical-proportional-factor (TPF15) is one of the indirect highest-oxygen-consumptions (HOC) assessment methods, but it may not accurately reflect the physiological differences across various sports (cycling-triathlon-... Read More about Highest oxygen consumption prediction: introducing variable theoretical proportional factors for different sports.

Pediatric wrist fractures: variations in management across countries. An evidence-based summary of evidence (2024)
Journal Article
Labianca, L., Calderaro, C., & Maffulli, N. (2024). Pediatric wrist fractures: variations in management across countries. An evidence-based summary of evidence. British Medical Bulletin, 152(1), 28-34. https://doi.org/10.1093/bmb/ldae014

Introduction Fractures of the distal radius are common in pediatric population, with considerable variation in the management of pediatric wrist fractures across different countries. It is crucial to consider the different approaches to conservative... Read More about Pediatric wrist fractures: variations in management across countries. An evidence-based summary of evidence.

Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols (2024)
Journal Article
Butt, S. E., Kepski, K., Sotiropoulos, J.-M., & Moran, W. J. (2024). Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols. Beilstein Journal of Organic Chemistry, 20, 2455-2460. https://doi.org/10.3762/bjoc.20.209

A change in mechanism was observed in the hypervalent iodine mediated cyclization of N-alkenylamides when the carbon chain between the alkene and the amide increased from two to three atoms. In the latter case, cyclization at the amide nitrogen to fo... Read More about Hypervalent iodine mediated cyclization of bishomoallylamides to prolinols.

Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence (2024)
Journal Article
Gupta, A., & Maffulli, N. (2024). Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence. Pain and Therapy, 13(6), 1377-1386. https://doi.org/10.1007/s40122-024-00661-y

Introduction: Osteoarthritis (OA) of the knee affects millions of people with sizable socioeconomic burden. Conventional treatment modalities are prioritized, turning to surgical intervention only when they have failed. However, these traditional mod... Read More about Platelet Lysate and Osteoarthritis of the Knee: A Review of Current Clinical Evidence.

Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography (2024)
Journal Article
Dimmock, R., Zhang, Y., Butt, G., Rauz, S., Huang, Z., & Yang, Y. (in press). Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography. Journal of Biophotonics, Article e202400172. https://doi.org/10.1002/jbio.202400172

The limbal niche is an adult source of epithelial stem cells which regenerate the cornea epithelium. The architecture and biomechanical properties of the limbus have previously been demonstrated to change due to aging and disease. This study aims to... Read More about Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography.

Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Vaishya, R., Kämmer, D., & Maffulli, N. (2024). Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review. British Medical Bulletin, 152(1), 16-27. https://doi.org/10.1093/bmb/ldae011

Introduction
Historically, anterior cruciate ligament (ACL) ruptures in the paediatric age group were managed conservatively with bracing, casting, activity modification, and physical therapy. However, most of these patients had to reduce their spor... Read More about Bone-patellar tendon-bone, hamstring, and quadriceps tendon autografts for anterior cruciate ligament reconstruction in skeletally immature patients: a systematic review.

Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review (2024)
Journal Article
Migliorini, F., Maffulli, N., Memminger, M. K., Simeone, F., Rath, B., & Huber, T. (in press). Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review. Archives of Orthopaedic and Trauma Surgery, https://doi.org/10.1007/s00402-024-05579-w

Introduction
In orthopaedic research, it is crucial to determine changes that are statistically significant and clinically meaningful. One approach to accomplish this is by calculating the Minimal Clinically Important Difference (MCID), the Clinical... Read More about Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review.

MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation (2024)
Journal Article
Al Saihati, H. A., Dessouky, A. A., Salim, R. F., Elgohary, I., El-Sherbiny, M., Ali, F. E. M., Moustafa, M. M. A., Shaheen, D., Forsyth, N. R., Badr, O. A., & Ebrahim, N. (in press). MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation. Stem Cell Research and Therapy, 15(1), 1-22. https://doi.org/10.1186/s13287-024-03889-9

Background: Coronavirus disease 2019 (COVID-19) has created a global pandemic with significant morbidity and mortality. SARS-CoV-2 primarily infects the lungs and is associated with various organ complications. Therapeutic approaches to combat COVID-... Read More about MSC–extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation.

Sacroiliac joint pain: what treatment and when. (2024)
Journal Article
Cocconi, F., Maffulli, N., Bell, A., Memminger, M. K., Simeone, F., & Migliorini, F. (in press). Sacroiliac joint pain: what treatment and when. Expert Review of Neurotherapeutics, 1-8. https://doi.org/10.1080/14737175.2024.2400682

Spinal and non-spinal pathologies can cause low back pain. Non-spinal sources of low back pain include the sacroiliac joint (SIJ) and the hip. SIJ pain can be treated either conservatively or surgically. Current strategies for managing sacroiliac joi... Read More about Sacroiliac joint pain: what treatment and when..

Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis (2024)
Journal Article
Migliorini, F., Betsch, M., Maffulli, N., Schäfer, L., Hildebrand, F., Kubach, J., & Pasurka, M. (in press). Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis. Scientific Reports, 14(1), Article 21162. https://doi.org/10.1038/s41598-024-71326-1

The present Bayesian network meta-analysis compared different types of polyethylene liners in total hip arthroplasty (THA) in terms of wear penetration (mm/year) and rate of revision. The type of liners compared were the crosslinked ultra-high molecu... Read More about Rate of revision and wear penetration in different polyethylene liner compositions in total hip arthroplasty: a Bayesian network meta-analysis.

Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma (2024)
Journal Article
Lan, Y.-L., Zou, S., & Chen, R. (2024). Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma. Annals of Medicine, 56(1), https://doi.org/10.1080/07853890.2024.2401111

Aquaporin 4 (AQP4) isabundant in the human brain and has an important role in brain homeostatsis and diseases. AQP4 expression has been found to be associated with glioma malignancies. However, the complete understanding of the biological processes... Read More about Update on the intriguing roles of AQP4 expression and redistribution in the progression and treatment of glioma.

Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review (2024)
Journal Article
Lucenti, L., Maffulli, N., Bardazzi, T., Saggini, R., Memminger, M., Simeone, F., & Migliorini, F. (in press). Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review. Journal of Clinical Medicine, 13(17), https://doi.org/10.3390/jcm13175219

Background: Femoroacetabular impingement (FAI) is common. The present systematic review updates the current evidence on return to sport (RTS) in patients who have undergone arthroscopic surgery for FAI in any of its variants (CAM, pincer, or both). M... Read More about Return to Sport Following Arthroscopic Management of Femoroacetabular Impingement: A Systematic Review.

State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons (2024)
Journal Article
Basso, V., Döbrössy, M. D., Thompson, L. H., Kirik, D., Fuller, H. R., & Gates, M. A. (2024). State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons. Biology, 13(9), 690. https://doi.org/10.3390/biology13090690

Dopaminergic neurons in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNpc) comprise around 75% of all dopaminergic neurons in the human brain. While both groups of dopaminergic neurons are in close proximity in the midbrai... Read More about State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons.

Pharmacological management of secondary chronic spinal cord injury: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Simeone, F., Jeyaraman, M., & Maffulli, N. (2024). Pharmacological management of secondary chronic spinal cord injury: a systematic review. British Medical Bulletin, 151(1), 49–68. https://doi.org/10.1093/bmb/ldae009

Introduction Spinal cord injury (SCI) may bring lifelong consequences for affected patients and a high financial burden to the health care system. Source of data Published peer-reviewed scientific articles identified from EMBASE, Google Scholar, PubM... Read More about Pharmacological management of secondary chronic spinal cord injury: a systematic review.

A novel neuronal circuit: Tanycytes mediate defensive metabolic responses following acute high‐temperature exposure (2024)
Journal Article
Chen, Q., Brüning‐Richardson, A., Chen, R., Zou, S., & Lan, Y. (2024). A novel neuronal circuit: Tanycytes mediate defensive metabolic responses following acute high‐temperature exposure. Brain-X, 2(3), 1-3. https://doi.org/10.1002/brx2.70003

The core body temperature, plays a vital role in influencing metabolic rate, enzyme activity, and various other physiological processes.1 Significant progress has been achieved in unraveling the neural mechanisms responsible for lowering body tempera... Read More about A novel neuronal circuit: Tanycytes mediate defensive metabolic responses following acute high‐temperature exposure.